Protein: TPL
Protein TOPLESS (WUS-interacting protein 1)

Gene: TPL
Organism: Arabidopsis thaliana
Interactions: 175
UniProt ID: Q94AI7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0009733 - response to auxin
GO:0009867 - jasmonic acid mediated signaling pathway
GO:0010051 - xylem and phloem pattern formation
GO:0010072 - primary shoot apical meristem specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1375638

TPL
Protein TOPLESS

5

15

Small-scale

0.938

High

1375706

NINJA
AFP homolog 2

4

5

Small-scale

0.694

High

200717

IAA16
Auxin-responsive protein IAA16

3

20

High-throughput

0.656

High

886017

IAA2
Auxin-responsive protein IAA2

3

20

High-throughput

0.656

High

1181955

IAA10
Auxin-responsive protein IAA10

3

20

High-throughput

0.656

High

1181995

IAA11
Auxin-responsive protein IAA11

3

20

High-throughput

0.656

High

1181859

IAA7
Auxin-responsive protein IAA7

3

20

Small-scale

0.653

High

200822

IAA19
Auxin-responsive protein IAA19

3

20

High-throughput

0.639

High

1319582

TIF5A
Protein TIFY 5A

3

0

Small-scale

0.628

High

198960

MSI4
WD-40 repeat-containing protein MSI4

1

18

High-throughput

0.621

High

1375649

SUVH3
Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH3

1

2

High-throughput

0.621

High

1375666

VIL1
VIN3-like protein 1

1

1

High-throughput

0.621

High

1342745

BZR1
Protein BRASSINAZOLE-RESISTANT 1

2

6

Small-scale

0.620

High

1318305

NPR3
Regulatory protein NPR3

2

16

High-throughput

0.620

High

264821

SOC1
MADS-box protein SOC1

2

3

High-throughput

0.613

High

885974

IAA1
Auxin-responsive protein IAA1

2

20

High-throughput

0.613

High

1250946

WOX4
WUSCHEL-related homeobox 4

2

8

High-throughput

0.613

High

1300061

Q8GYE4
Myb-like HTH transcriptional regulator family protein

2

8

High-throughput

0.613

High

1372988

KAN1
Transcription repressor KAN1

2

8

High-throughput

0.613

High

1375665

TI11A
Protein TIFY 11A

2

11

High-throughput

0.613

High

1375678

TOE2
AP2-like ethylene-responsive transcription factor TOE2

2

20

High-throughput

0.613

High

1375712

IAA27
Auxin-responsive protein IAA27

2

20

High-throughput

0.613

High

868639

AP2
Floral homeotic protein APETALA 2

2

20

Small-scale

0.609

High

307586

SPL
Protein SPOROCYTELESS

2

4

Small-scale

0.584

High

749520

IAA4
Auxin-responsive protein IAA4

2

20

High-throughput

0.584

High

1182067

IAA13
Auxin-responsive protein IAA13

2

20

High-throughput

0.584

High

1182219

AGL15
Agamous-like MADS-box protein AGL15

2

4

High-throughput

0.584

High

1354718

ASR3
Trihelix transcription factor ASR3

2

2

High-throughput

0.584

High

1375640

AFP3
Ninja-family protein AFP3

2

5

Small-scale

0.584

High

1375711

IAA28
Auxin-responsive protein IAA28

2

20

High-throughput

0.584

High

70689

A8MRG4
Histone acetyltransferase

3

2

Small-scale

0.583

High

1181786

IAA3
Auxin-responsive protein IAA3

2

20

Small-scale

0.576

High

1235978

APRR5
Two-component response regulator-like APRR5

1

3

Small-scale

0.573

High

1318145

APRR9
Two-component response regulator-like APRR9

1

3

Small-scale

0.573

High

1373013

APRR7
Two-component response regulator-like APRR7

1

3

Small-scale

0.573

High

1375671

BZR2
Protein BRASSINAZOLE-RESISTANT 2

1

6

Small-scale

0.573

High

1300709

WOX5
WUSCHEL-related homeobox 5

1

8

Small-scale

0.561

High

1082121

Q0WQ76
Uncharacterized protein At3g24150

1

2

Small-scale

0.552

High

200459

GRXS3
Monothiol glutaredoxin-S3

1

1

High-throughput

0.541

High

308521

NGA1
B3 domain-containing transcription factor NGA1

1

20

High-throughput

0.541

High

1181891

IAA8
Auxin-responsive protein IAA8

1

20

High-throughput

0.541

High

1375654

ERF80
Ethylene-responsive transcription factor 9

1

20

High-throughput

0.541

High

1375655

Q9FGW7
Emb|CAB62340.1

1

1

High-throughput

0.541

High

1375668

Q9LMC7
AT1G19000 protein

1

10

High-throughput

0.541

High

1375695

MYB3
Transcription factor MYB3

1

14

High-throughput

0.541

High

1375708

MYB4
Transcription repressor MYB4

1

14

High-throughput

0.541

High

198831

HDA19
Histone deacetylase 19

1

12

Small-scale

0.527

High

1182038

IAA12
Auxin-responsive protein IAA12

1

20

Small-scale

0.527

High

1375660

NIMI3
Protein NIM1-INTERACTING 3

1

0

High-throughput

0.518

High

1375676

NIMI2
Protein NIM1-INTERACTING 2

1

0

High-throughput

0.518

High

1375696

WUS
Protein WUSCHEL

1

8

Small-scale

0.506

High

307545

O81801
At4g35700

1

2

High-throughput

0.494

High

1375673

DRIPH
Probable E3 ubiquitin protein ligase DRIPH

1

15

High-throughput

0.494

High

75233

RVE7
Protein REVEILLE 7

1

10

High-throughput

0.481

High

90526

C0Z2P1
AT1G74840 protein

1

10

High-throughput

0.481

High

101607

F4J3S6
NAC domain containing protein 50

1

3

High-throughput

0.481

High

103866

RVE1
Protein REVEILLE 1

1

10

High-throughput

0.481

High

198945

ZAT6
Zinc finger protein ZAT6

1

7

High-throughput

0.481

High

199909

MYB73
Transcription factor MYB73

1

20

High-throughput

0.481

High

200774

IAA18
Auxin-responsive protein IAA18

1

20

High-throughput

0.481

High

200869

IAA20
Auxin-responsive protein IAA20

1

20

High-throughput

0.481

High

235924

MYB32
Transcription factor MYB32

1

14

High-throughput

0.481

High

265913

ZAT3
Zinc finger protein ZAT3

1

8

Small-scale

0.481

High

305872

ERF82
Ethylene-responsive transcription factor 3

1

20

High-throughput

0.481

High

305892

ERF78
Ethylene-responsive transcription factor 4

1

20

High-throughput

0.481

High

306680

AS1
Transcription factor AS1

1

19

High-throughput

0.481

High

306707

ZFP10
Zinc finger protein 10

1

7

High-throughput

0.481

High

307535

O81793
Zinc finger

1

4

High-throughput

0.481

High

857805

HAT1
Homeobox-leucine zipper protein HAT1

1

4

High-throughput

0.481

High

857868

HAT22
Homeobox-leucine zipper protein HAT22

1

2

High-throughput

0.481

High

976942

ARR12
Two-component response regulator ARR12

1

3

High-throughput

0.481

High

1020668

ZFP8
Zinc finger protein 8

1

7

High-throughput

0.481

High

1020750

IAA17
Auxin-responsive protein IAA17

1

20

High-throughput

0.481

High

1064199

CSK22
Casein kinase II subunit alpha-2

1

18

High-throughput

0.481

High

1169358

LEC2
B3 domain-containing transcription factor LEC2

1

20

High-throughput

0.481

High

1181925

IAA9
Auxin-responsive protein IAA9

1

20

High-throughput

0.481

High

1185102

ZFP3
Zinc finger protein 3

1

7

High-throughput

0.481

High

1185120

ZFP4
Zinc finger protein 4

1

7

High-throughput

0.481

High

1192504

MYB7
Transcription factor MYB7

1

14

High-throughput

0.481

High

1236566

Q6NLR3
E3 ubiquitin-protein ligase RMA

1

14

High-throughput

0.481

High

1250972

WOX2
WUSCHEL-related homeobox 2

1

8

High-throughput

0.481

High

1285165

ARFQ
Auxin response factor 17

1

18

High-throughput

0.481

High

1298893

BZP23
Basic leucine zipper 23

1

3

High-throughput

0.481

High

1300126

Y2608
B3 domain-containing protein At2g36080

1

20

High-throughput

0.481

High

1318515

JMJ19
Probable inactive lysine-specific demethylase JMJ19

1

5

High-throughput

0.481

High

1319297

IAA26
Auxin-responsive protein IAA26

1

20

High-throughput

0.481

High

1320451

TCP4
Transcription factor TCP4

1

5

High-throughput

0.481

High

1354248

Q8VY17
DNA-binding bromodomain-containing protein

1

10

High-throughput

0.481

High

1355042

HHO2
Transcription factor HHO2

1

6

High-throughput

0.481

High

1372682

TCP2
Transcription factor TCP2

1

5

High-throughput

0.481

High

1373595

TIF9
Protein TIFY 9

1

12

Small-scale

0.481

High

1375642

ERF81
Ethylene-responsive transcription factor 12

1

20

High-throughput

0.481

High

1375643

ARFB
Auxin response factor 2

1

20

High-throughput

0.481

High

1375645

ZAT10
Zinc finger protein ZAT10

1

7

High-throughput

0.481

High

1375646

HSFB1
Heat stress transcription factor B-1

1

11

High-throughput

0.481

High

1375648

ERF76
Ethylene-responsive transcription factor 11

1

20

High-throughput

0.481

High

1375650

RAVL3
AP2/ERF and B3 domain-containing transcription factor At1g51120

1

20

High-throughput

0.481

High

1375651

RAVL1
AP2/ERF and B3 domain-containing transcription repressor TEM1

1

20

High-throughput

0.481

High

1375652

RAVL2
AP2/ERF and B3 domain-containing transcription factor At1g50680

1

20

High-throughput

0.481

High

1375653

TI11B
Protein TIFY 11B

1

12

High-throughput

0.481

High

1375656

GAT16
GATA transcription factor 16

1

9

High-throughput

0.481

High

1375659

Y5625
B3 domain-containing protein At5g06250

1

20

High-throughput

0.481

High

1375661

BZIP9
Basic leucine zipper 9

1

4

High-throughput

0.481

High

1375664

ERF83
Ethylene-responsive transcription factor 7

1

20

High-throughput

0.481

High

1375667

TI10A
Protein TIFY 10A

1

12

High-throughput

0.481

High

1375669

AFP2
Ninja-family protein AFP2

1

5

Small-scale

0.481

High

1375672

HSOP1
Hsp70-Hsp90 organizing protein 1

1

11

High-throughput

0.481

High

1375674

BH121
Transcription factor bHLH121

1

2

High-throughput

0.481

High

1375682

EMF1
Protein EMBRYONIC FLOWER 1

1

1

High-throughput

0.481

High

1375685

IAA30
Auxin-responsive protein IAA30

1

20

High-throughput

0.481

High

1375686

NGA2
B3 domain-containing transcription factor NGA2

1

20

High-throughput

0.481

High

1375687

AGL18
Agamous-like MADS-box protein AGL18

1

4

High-throughput

0.481

High

1375691

TCP3
Transcription factor TCP3

1

5

High-throughput

0.481

High

1375692

ERF79
Ethylene-responsive transcription factor 8

1

20

High-throughput

0.481

High

1375693

NGA3
B3 domain-containing transcription factor NGA3

1

20

High-throughput

0.481

High

1375698

ZAT2
Zinc finger protein ZAT2

1

8

Small-scale

0.481

High

1375699

Q9SIZ5
Homeodomain-like superfamily protein

1

8

High-throughput

0.481

High

1375700

RAP27
Ethylene-responsive transcription factor RAP2-7

1

20

High-throughput

0.481

High

1375701

SPL1
Squamosa promoter-binding-like protein 1

1

3

High-throughput

0.481

High

1375702

MYB77
Transcription factor MYB77

1

20

High-throughput

0.481

High

1375703

MB3R2
Transcription factor MYB3R-2

1

20

High-throughput

0.481

High

1375704

NAC52
NAC domain containing protein 52

1

3

High-throughput

0.481

High

1375707

AGL21
Agamous-like MADS-box protein AGL21

1

3

High-throughput

0.481

High

1375709

HFB2B
Heat stress transcription factor B-2b

1

11

High-throughput

0.481

High

1375710

ARFI
Auxin response factor 9

1

20

High-throughput

0.481

High

1375713

ERF77
Ethylene-responsive transcription factor 10

1

20

High-throughput

0.481

High

1375714

RAV1
AP2/ERF and B3 domain-containing transcription factor RAV1

1

20

High-throughput

0.481

High

939056

SUMO1
Small ubiquitin-related modifier 1

1

3

Small-scale

0.479

High

1183039

KSG7
Shaggy-related protein kinase eta

1

13

High-throughput

0.479

High

1375657

HDA6
Histone deacetylase 6

1

11

Small-scale

0.479

High

99495

RTEL1
Regulator of telomere elongation helicase 1 homolog

1

0

High-throughput

0.460

High

101506

JAZ13
Protein JAZ13

1

0

Small-scale

0.460

High

101911

F4J9Z8
Homeodomain-like superfamily protein

1

0

High-throughput

0.460

High

1298902

UGPI6
Uncharacterized GPI-anchored protein At1g61900

1

0

High-throughput

0.460

High

1299951

TIF4B
Protein TIFY 4B

1

0

High-throughput

0.460

High

1341748

Y2172
B3 domain-containing protein At2g31720

1

0

High-throughput

0.460

High

1355018

REM3
B3 domain-containing protein REM3

1

0

High-throughput

0.460

High

1375683

SORIN
Sororin-like protein

1

0

High-throughput

0.460

High

1375697

ZWIP3
Zinc finger protein WIP3

1

0

High-throughput

0.460

High

1284183

TIF8
Protein TIFY 8

1

0

Small-scale

0.458

High

1284853

PCH1
Protein PHOTOPERIODIC CONTROL OF HYPOCOTYL 1

1

0

Small-scale

0.458

High

1180718

Q2VWA2
Auxin-responsive protein

1

20

High-throughput

0.457

High

1283896

Q84JY3
Histone acetyltransferase

1

2

High-throughput

0.457

High

1375694

Q9S7N6
F25A4.19 protein

1

10

High-throughput

0.457

High

146618

GRXS9
Monothiol glutaredoxin-S9

1

1

High-throughput

0.439

High

1298908

Q8GUJ6
At4g28530

1

3

High-throughput

0.439

High

1354459

Q8VYI7
At1g80610/T21F11_6

1

2

High-throughput

0.439

High

1375454

ARI1
Probable E3 ubiquitin-protein ligase ARI1

1

2

High-throughput

0.439

High

1375658

LBD37
LOB domain-containing protein 37

1

10

High-throughput

0.439

High

1375662

Q9FWW2
T28K15.14 protein

1

1

High-throughput

0.439

High

1375663

Q9FWY3
T14P4.7 protein

1

14

High-throughput

0.439

High

1375680

FB212
F-box protein At3g59150

1

2

High-throughput

0.439

High

1375681

FB206
Putative F-box protein At3g58820

1

2

High-throughput

0.439

High

1375688

Q9M2U8
At3g54390

1

1

High-throughput

0.439

High

1375689

LBD41
LOB domain-containing protein 41

1

10

High-throughput

0.439

High

1375690

Q9M9X2
F18C1.6 protein

1

19

High-throughput

0.439

High

1375705

MCT14
Multiple C2 domain and transmembrane region protein 14

1

1

High-throughput

0.439

High

99437

MD10B
Mediator of RNA polymerase II transcription subunit 10b

1

0

Small-scale

0.286

High

89647

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

Small-scale

0.286

High

101477

BASS4
Probable sodium/metabolite cotransporter BASS4, chloroplastic

1

0

High-throughput

0.251

Low

103836

S40A2
Solute carrier family 40 member 2

1

0

High-throughput

0.251

Low

235670

INDH
Iron-sulfur protein required for NADH dehydrogenase, mitochondrial

1

0

High-throughput

0.251

Low

305999

GPAT6
Glycerol-3-phosphate 2-O-acyltransferase 6

1

0

High-throughput

0.251

Low

1236458

LIL32
Light-harvesting complex-like protein 3 isotype 2, chloroplastic

1

0

High-throughput

0.251

Low

1284334

Q84MC3
At3g47980

1

0

High-throughput

0.251

Low

1375639

WIP3
WPP domain-interacting protein 3

1

0

High-throughput

0.251

Low

1375641

CX172
Cytochrome c oxidase copper chaperone 2

1

0

High-throughput

0.251

Low

1375644

TPC1
Two pore calcium channel protein 1

1

0

High-throughput

0.251

Low

1375647

Q9ASZ4
AT3g17900/MEB5_12

1

0

High-throughput

0.251

Low

1375670

Q9LMX9
F21F23.12 protein

1

0

High-throughput

0.251

Low

1375675

CALS4
Callose synthase 4

1

0

High-throughput

0.251

Low

1375677

Q9LVC4
Ras guanine nucleotide exchange factor Q-like protein

1

0

High-throughput

0.251

Low

1375679

Q9LW03
At3g15760

1

0

High-throughput

0.251

Low

1375684

Q9LZ71
AT5g04550/T32M21_140

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025