Protein: TEM1
Protein TEM1

Gene: TEM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 189
UniProt ID: P38987

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005816 - spindle pole body
GO:0023056 - positive regulation of signaling
GO:0031536 - positive regulation of exit from mitosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

643016

BUB2
Mitotic check point protein BUB2

8

20

Small-scale

0.970

High

649891

CDC15
Cell division control protein 15

7

12

Small-scale

0.963

High

758676

BFA1
Mitotic check point protein BFA1

16

0

Small-scale

0.731

High

758723

IQG1
Ras GTPase-activating-like protein IQG1

2

19

Small-scale

0.700

High

747767

AMN1
Antagonist of mitotic exit network protein 1

4

1

Small-scale

0.697

High

758657

TEM1
Protein TEM1

1

20

Small-scale

0.692

High

676049

XPO1
Exportin-1

1

3

High-throughput

0.691

High

339632

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.618

High

605531

DBF2
Cell cycle protein kinase DBF2

1

9

High-throughput

0.618

High

693112

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

7

Small-scale

0.618

High

758686

RHO5
GTP-binding protein RHO5

1

19

High-throughput

0.618

High

687873

NUD1
Protein NUD1

2

10

Small-scale

0.586

High

431365

LTE1
Guanine nucleotide exchange factor LTE1

1

0

Small-scale

0.586

High

623823

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

3

High-throughput

0.579

High

628974

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.578

High

633222

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.578

High

758689

CDC14
Tyrosine-protein phosphatase CDC14

1

10

Small-scale

0.573

High

758709

NMA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

1

High-throughput

0.566

High

758710

ATG17
Autophagy-related protein 17

2

1

High-throughput

0.566

High

554643

HSP26
Heat shock protein 26

2

1

High-throughput

0.565

High

636624

CDC48
Cell division control protein 48

2

8

High-throughput

0.558

High

698347

ELM1
Serine/threonine-protein kinase ELM1

1

8

High-throughput

0.555

High

614647

KC11
Casein kinase I homolog 1

1

13

High-throughput

0.553

High

691050

HOG1
Mitogen-activated protein kinase HOG1

1

3

High-throughput

0.553

High

704595

SEC3
Exocyst complex component SEC3

1

12

High-throughput

0.553

High

758691

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

3

High-throughput

0.553

High

758722

GIN4
Serine/threonine-protein kinase GIN4

1

18

High-throughput

0.553

High

758671

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

2

3

High-throughput

0.543

High

632530

DMC1
Meiotic recombination protein DMC1

2

2

High-throughput

0.539

High

723835

DHSO1
Sorbitol dehydrogenase 1

2

2

High-throughput

0.539

High

594401

SAR1
Small COPII coat GTPase SAR1

1

20

High-throughput

0.536

High

690927

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

3

High-throughput

0.536

High

748446

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

5

High-throughput

0.536

High

605645

KIN3
Serine/threonine-protein kinase KIN3

1

13

High-throughput

0.528

High

571893

SKI3
Superkiller protein 3

1

0

High-throughput

0.517

High

622020

SSD1
Protein SSD1

1

0

High-throughput

0.513

High

758701

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.513

High

360876

TBB
Tubulin beta chain

1

6

High-throughput

0.500

High

368059

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.500

High

454322

TBA1
Tubulin alpha-1 chain

1

7

High-throughput

0.500

High

454604

TBA3
Tubulin alpha-3 chain

1

8

High-throughput

0.500

High

664822

BMH1
Protein BMH1

1

2

High-throughput

0.500

High

687377

EF2
Elongation factor 2

1

2

High-throughput

0.500

High

758702

ATG16
Autophagy protein 16

1

0

High-throughput

0.494

High

341661

ARGI
Arginase

1

1

High-throughput

0.494

High

541547

AMPL
Vacuolar aminopeptidase 1

1

3

High-throughput

0.494

High

755606

DNPEP
Aspartyl aminopeptidase 4

1

3

High-throughput

0.494

High

758683

PRA1
Prenylated Rab acceptor 1

1

16

High-throughput

0.494

High

424082

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

High-throughput

0.489

High

485730

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.489

High

540580

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.489

High

562234

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.489

High

596641

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

6

High-throughput

0.489

High

637129

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

3

High-throughput

0.489

High

703155

UFD4
Ubiquitin fusion degradation protein 4

1

4

High-throughput

0.489

High

744993

DUG2
Probable di- and tripeptidase DUG2

1

1

High-throughput

0.489

High

752094

YHJ3
Uncharacterized protein YHR033W

1

2

High-throughput

0.489

High

758660

FHP
Flavohemoprotein

1

1

High-throughput

0.489

High

758678

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

5

High-throughput

0.489

High

758697

COFI
Cofilin

1

2

High-throughput

0.489

High

758699

HAS1
ATP-dependent RNA helicase HAS1

1

3

High-throughput

0.489

High

758700

CLU
Clustered mitochondria protein 1

1

1

High-throughput

0.489

High

758703

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.489

High

758707

YM71
NADP-dependent 3-hydroxy acid dehydrogenase

1

6

High-throughput

0.489

High

758719

YTM1
Ribosome biogenesis protein YTM1

1

6

High-throughput

0.489

High

758716

PRM3
Pheromone-regulated membrane protein 3

1

0

High-throughput

0.486

High

758718

CDC53
Cell division control protein 53

1

6

Small-scale

0.479

High

710546

UBX1
UBX domain-containing protein 1

1

1

High-throughput

0.470

High

659159

LAC1
Ceramide synthase LAC1

1

1

High-throughput

0.464

High

700722

MNS1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

1

High-throughput

0.464

High

758665

WRIP1
DNA-dependent ATPase MGS1

1

6

High-throughput

0.464

High

758704

HMO1
High mobility group protein 1

1

5

High-throughput

0.464

High

758708

ECI1
3,2-trans-enoyl-CoA isomerase

1

2

High-throughput

0.464

High

758712

DHSO2
Sorbitol dehydrogenase 2

1

2

High-throughput

0.464

High

343606

PMG1
Phosphoglycerate mutase 1

1

2

High-throughput

0.457

High

378345

LEU3
3-isopropylmalate dehydrogenase

1

1

High-throughput

0.457

High

381458

GAL1
Galactokinase

1

1

High-throughput

0.457

High

381705

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

3

High-throughput

0.457

High

389282

HXKA
Hexokinase-1

1

4

High-throughput

0.457

High

410998

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.457

High

423847

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.457

High

452995

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

498520

METK1
S-adenosylmethionine synthase 1

1

2

High-throughput

0.457

High

520832

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

8

High-throughput

0.457

High

543734

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.457

High

556046

VATB
V-type proton ATPase subunit B

1

9

High-throughput

0.457

High

558626

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

5

High-throughput

0.457

High

560660

BIP
Endoplasmic reticulum chaperone BiP

1

10

High-throughput

0.457

High

562383

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.457

High

570693

HXKG
Glucokinase-1

1

4

High-throughput

0.457

High

583224

METK2
S-adenosylmethionine synthase 2

1

2

High-throughput

0.457

High

604411

CLH
Clathrin heavy chain

1

4

High-throughput

0.457

High

619575

MPCP
Mitochondrial phosphate carrier protein

1

3

High-throughput

0.457

High

712917

BMH2
Protein BMH2

1

2

High-throughput

0.457

High

758658

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.457

High

758675

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.457

High

758715

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

2

High-throughput

0.457

High

758717

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

2

High-throughput

0.457

High

758726

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.457

High

342016

ATPB
ATP synthase subunit beta, mitochondrial

1

9

High-throughput

0.437

High

410378

SC160
Protein SCP160

1

4

High-throughput

0.437

High

597237

PSA7
Probable proteasome subunit alpha type-7

1

2

High-throughput

0.437

High

687697

BTAF1
TATA-binding protein-associated factor MOT1

1

5

High-throughput

0.437

High

688036

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

4

High-throughput

0.437

High

688977

VA0D
V-type proton ATPase subunit d

1

2

High-throughput

0.437

High

698235

CACP
Carnitine O-acetyltransferase, mitochondrial

1

1

High-throughput

0.437

High

716180

SKI2
Antiviral helicase SKI2

1

1

High-throughput

0.437

High

734007

NU133
Nucleoporin NUP133

1

1

High-throughput

0.437

High

752283

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

4

High-throughput

0.437

High

756244

KEL1
Kelch repeat-containing protein 1

1

1

Small-scale

0.437

High

758659

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

758661

BDH1
(R,R)-butanediol dehydrogenase

1

2

High-throughput

0.437

High

758666

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

2

High-throughput

0.437

High

758667

TM108
Protein TMA108

1

5

High-throughput

0.437

High

758670

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

6

High-throughput

0.437

High

758674

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.437

High

758679

KEL2
Kelch repeat-containing protein 2

1

1

Small-scale

0.437

High

758685

IPI3
Pre-rRNA-processing protein IPI3

1

4

High-throughput

0.437

High

758687

NOP13
Nucleolar protein 13

1

6

High-throughput

0.437

High

758694

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

1

High-throughput

0.437

High

478193

HSP77
Import motor subunit, mitochondrial

1

11

High-throughput

0.407

High

511313

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.407

High

694701

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.407

High

758664

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.407

High

730752

NDK
Nucleoside diphosphate kinase

2

0

High-throughput

0.330

High

757246

CH10
10 kDa heat shock protein, mitochondrial

2

0

High-throughput

0.323

High

758720

HUA2
Protein HUA2

2

0

High-throughput

0.323

High

758680

NIF3
NGG1-interacting factor 3

2

0

High-throughput

0.317

High

758698

DIG1
Down-regulator of invasive growth 1

2

0

High-throughput

0.314

High

758663

EDC3
Enhancer of mRNA-decapping protein 3

2

0

High-throughput

0.307

High

758677

YJ26
Uncharacterized protein YJR056C

2

0

High-throughput

0.307

High

400158

HEM2
Delta-aminolevulinic acid dehydratase

1

0

High-throughput

0.282

High

448207

F16P
Fructose-1,6-bisphosphatase

1

0

High-throughput

0.282

High

567475

KHSE
Homoserine kinase

1

0

High-throughput

0.282

High

699336

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.282

High

744538

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.282

High

747663

YBY7
UPF0303 protein YBR137W

1

0

High-throughput

0.282

High

758662

HPA3
D-amino-acid N-acetyltransferase HPA3

1

0

High-throughput

0.282

High

758668

YJV8
Putative acetyltransferase YJL218W

1

0

High-throughput

0.282

High

421765

KAD2
Adenylate kinase

1

0

High-throughput

0.279

Low

424863

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.279

Low

426381

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

456696

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

0

High-throughput

0.279

Low

599176

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

0

High-throughput

0.279

Low

680276

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.279

Low

690585

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.279

Low

693789

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.279

Low

704298

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.279

Low

730629

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.279

Low

756345

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.279

Low

758672

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

758681

YG29
Uncharacterized protein YGR066C

1

0

High-throughput

0.279

Low

758706

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

758724

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.279

Low

140780

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.265

Low

707196

SEC66
Translocation protein SEC66

1

0

High-throughput

0.265

Low

756895

AIM18
Altered inheritance of mitochondria protein 18, mitochondrial

1

0

High-throughput

0.265

Low

758673

BIT61
Target of rapamycin complex 2 subunit BIT61

1

0

High-throughput

0.265

Low

758684

SNZ2
Probable pyridoxal 5'-phosphate synthase subunit SNZ2

1

0

High-throughput

0.265

Low

758688

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.265

Low

758721

WTM2
Transcriptional modulator WTM2

1

0

High-throughput

0.265

Low

754333

GIC1
GTPase-interacting component 1

1

0

Small-scale

0.261

Low

342367

CISY1
Citrate synthase, mitochondrial

1

0

High-throughput

0.261

Low

404335

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.261

Low

424522

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.261

Low

537417

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

549671

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

584159

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.261

Low

588077

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

605032

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.261

Low

758669

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.261

Low

758695

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.261

Low

588989

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

High-throughput

0.249

Low

699786

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

755814

LSM12
Protein LSM12

1

0

High-throughput

0.249

Low

756736

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.249

Low

758682

YG5X
Putative methyltransferase YGR283C

1

0

High-throughput

0.249

Low

758690

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.249

Low

758693

MAP1
Methionine aminopeptidase 1

1

0

High-throughput

0.249

Low

758696

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.249

Low

758705

ARMT1
Damage-control phosphatase YMR027W

1

0

High-throughput

0.249

Low

758711

TRM3
tRNA

1

0

High-throughput

0.249

Low

758713

CMS1
Protein CMS1

1

0

High-throughput

0.249

Low

758714

GSHB
Glutathione synthetase GSH2

1

0

High-throughput

0.249

Low

758725

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.249

Low

636099

YCX7
Putative uncharacterized protein YCR087W

1

0

High-throughput

0.238

Low

754078

RRF1
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.238

Low

758692

BLH1
Cysteine proteinase 1, mitochondrial

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024