Protein: LSM5
U6 snRNA-associated Sm-like protein LSm5

Gene: LSM5
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: P40089

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

768230

LSM1
Sm-like protein LSm1

15

15

Small-scale

0.984

High

635869

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

11

1

Small-scale

0.977

High

768245

LSM3
U6 snRNA-associated Sm-like protein LSm3

9

17

Small-scale

0.972

High

768254

LSM6
U6 snRNA-associated Sm-like protein LSm6

9

6

Small-scale

0.971

High

746297

LSM2
U6 snRNA-associated Sm-like protein LSm2

7

7

Small-scale

0.965

High

768241

LSM7
U6 snRNA-associated Sm-like protein LSm7

6

14

Small-scale

0.934

High

768232

LSM8
U6 snRNA-associated Sm-like protein LSm8

5

14

Small-scale

0.924

High

767779

LSM4
U6 snRNA-associated Sm-like protein LSm4

4

3

Small-scale

0.909

High

704675

PRP8
Pre-mRNA-splicing factor 8

4

0

Small-scale

0.850

High

768253

SMD2
Small nuclear ribonucleoprotein Sm D2

2

2

High-throughput

0.800

High

768234

PRP24
U4/U6 snRNA-associated-splicing factor PRP24

3

0

Small-scale

0.796

High

731730

SN114
Pre-mRNA-splicing factor SNU114

2

0

High-throughput

0.761

High

697215

BRR2
Pre-mRNA-splicing helicase BRR2

6

2

Small-scale

0.722

High

605056

XRN1
5'-3' exoribonuclease 1

5

0

High-throughput

0.684

High

768222

RUXG
Small nuclear ribonucleoprotein G

1

13

High-throughput

0.665

High

586410

PRP6
Pre-mRNA-splicing factor 6

2

2

High-throughput

0.621

High

589080

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

2

High-throughput

0.621

High

766910

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

2

High-throughput

0.618

High

768248

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

1

High-throughput

0.618

High

768220

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

0

Small-scale

0.589

High

768267

DCP1
mRNA-decapping enzyme subunit 1

2

0

Small-scale

0.576

High

690934

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.549

High

627540

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.508

High

768259

TRM3
tRNA

1

1

High-throughput

0.508

High

768243

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.493

High

140781

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.486

High

409999

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.486

High

604563

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.486

High

768228

YFG6
Y' element ATP-dependent helicase YFL066C

1

0

High-throughput

0.486

High

768265

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

High-throughput

0.486

High

768263

CLF1
Pre-mRNA-splicing factor CLF1

1

3

Small-scale

0.479

High

768264

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

480133

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.460

High

548408

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

0

High-throughput

0.458

High

634625

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

662358

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

675745

RENT1
ATP-dependent helicase NAM7

1

0

Small-scale

0.458

High

696870

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

735276

RM07
Large ribosomal subunit protein uL5m

1

0

High-throughput

0.458

High

761952

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

768229

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

768244

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

768249

CWC21
Pre-mRNA-splicing factor CWC21

1

0

Small-scale

0.458

High

768250

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

768251

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

768256

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

768261

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

768262

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

511495

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

768221

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

743548

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

761124

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

695982

HSP79
Heat shock protein homolog SSE2

1

0

High-throughput

0.426

High

522420

STE6
Alpha-factor-transporting ATPase

1

0

High-throughput

0.265

Low

539987

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.265

Low

629809

SYNM
Asparagine--tRNA ligase, mitochondrial

1

0

High-throughput

0.265

Low

741186

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.265

Low

753608

YHA8
Uncharacterized transporter YHL008C

1

0

High-throughput

0.265

Low

765227

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.265

Low

768225

ATC7
Phospholipid-transporting ATPase NEO1

1

0

High-throughput

0.265

Low

768227

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.265

Low

768231

ALY2
Arrestin-related trafficking adapter 3

1

0

High-throughput

0.265

Low

768233

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.265

Low

768255

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.265

Low

768260

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

520527

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.249

Low

534487

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.249

Low

589383

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

607419

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low

607488

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.249

Low

615611

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.249

Low

629857

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.249

Low

635372

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

635782

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

679562

RM09
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.249

Low

689503

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

689586

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

700276

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

700926

SMY2
Protein SMY2

1

0

Small-scale

0.249

Low

710675

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.249

Low

729799

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.249

Low

735142

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.249

Low

735208

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.249

Low

735331

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

735396

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

735449

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

735510

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

735559

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

735600

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

735660

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

735723

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.249

Low

735765

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

735793

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

735826

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.249

Low

743348

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

762244

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

768224

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

768226

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.249

Low

768235

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

768236

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

768237

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

768238

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

768239

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

768240

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

768242

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.249

Low

768246

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

768247

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

768252

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

768257

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low

768258

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

768266

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.249

Low

478240

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

543830

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

705233

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

731108

LHS1
Heat shock protein 70 homolog LHS1

1

0

High-throughput

0.232

Low

768223

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024