Protein: ATAD2
ATPase histone chaperone YTA7 (EC 3.6.1.-) (ATPase family AAA domain-containing protein YTA7) (AAA-ATPase) (Tat-binding homolog 7)

Gene: ATAD2, YTA7
Organism: Saccharomyces cerevisiae S288C
Interactions: 195
UniProt ID: P40340

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751311

RFC1
Replication factor C subunit 1

2

6

High-throughput

0.754

High

636645

CDC48
Cell division control protein 48

2

17

High-throughput

0.737

High

772280

ATAD2
ATPase histone chaperone YTA7

2

18

High-throughput

0.737

High

772311

ORC1
Origin recognition complex subunit 1

2

7

High-throughput

0.737

High

772325

RUVB1
RuvB-like protein 1

2

7

High-throughput

0.737

High

772361

RUVB2
RuvB-like protein 2

2

7

High-throughput

0.737

High

772313

H3
Histone H3

6

14

Small-scale

0.719

High

692806

SPT16
FACT complex subunit SPT16

6

4

Small-scale

0.719

High

606031

RAD53
Serine/threonine-protein kinase RAD53

4

3

Small-scale

0.686

High

355908

H2B2
Histone H2B.2

4

6

High-throughput

0.672

High

356513

H4
Histone H4

4

5

High-throughput

0.672

High

392454

H2A2
Histone H2A.2

4

4

High-throughput

0.672

High

696215

STH1
Nuclear protein STH1/NPS1

4

5

Small-scale

0.672

High

710442

SAS3
Histone acetyltransferase SAS3

4

1

Small-scale

0.672

High

772331

POB3
FACT complex subunit POB3

4

1

Small-scale

0.672

High

772346

RSC3
Chromatin structure-remodeling complex protein RSC3

4

2

Small-scale

0.672

High

635511

RSC6
Chromatin structure-remodeling complex protein RSC6

4

0

Small-scale

0.643

High

772339

YL455
PWWP domain-containing protein YLR455W

4

0

Small-scale

0.643

High

772349

RSC58
Chromatin structure-remodeling complex protein RSC58

4

0

Small-scale

0.643

High

420133

TOP2
DNA topoisomerase 2

3

1

Small-scale

0.640

High

355504

H2B1
Histone H2B.1

3

6

High-throughput

0.633

High

697401

CHD1
Chromo domain-containing protein 1

3

3

High-throughput

0.633

High

744875

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

5

High-throughput

0.633

High

772317

RSC4
Chromatin structure-remodeling complex subunit RSC4

3

12

High-throughput

0.633

High

772321

HOS3
Histone deacetylase HOS3

3

8

High-throughput

0.633

High

772335

ARP9
Actin-like protein ARP9

3

5

High-throughput

0.633

High

772342

RSC2
Chromatin structure-remodeling complex subunit RSC2

3

11

High-throughput

0.633

High

772357

NTO1
NuA3 HAT complex component NTO1

3

3

High-throughput

0.633

High

772363

CMR1
DNA damage-binding protein CMR1

3

8

High-throughput

0.633

High

772365

H2AZ
Histone H2A.Z

3

6

High-throughput

0.633

High

339673

CDK1
Cyclin-dependent kinase 1

2

3

Small-scale

0.629

High

751268

RFC3
Replication factor C subunit 3

1

8

High-throughput

0.618

High

772281

RFC2
Replication factor C subunit 2

1

5

High-throughput

0.618

High

698660

RSC7
Chromatin structure-remodeling complex subunit RSC7

3

0

High-throughput

0.606

High

770086

RT106
Histone chaperone RTT106

3

0

Small-scale

0.606

High

772322

RSC9
Chromatin structure-remodeling complex subunit RSC9

3

0

High-throughput

0.606

High

772353

IOC2
ISWI one complex protein 2

3

0

High-throughput

0.606

High

392135

H2A1
Histone H2A.1

2

4

Small-scale

0.594

High

757942

CSK2C
Casein kinase II subunit beta'

3

4

Small-scale

0.587

High

375411

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

7

Small-scale

0.584

High

440043

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

5

Small-scale

0.584

High

558089

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

4

Small-scale

0.584

High

744774

MCM7
DNA replication licensing factor MCM7

2

4

Small-scale

0.584

High

772288

RSC8
Chromatin structure-remodeling complex protein RSC8

2

2

Small-scale

0.584

High

772290

CSK2B
Casein kinase II subunit beta

3

4

Small-scale

0.578

High

772312

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.575

High

584745

CSK22
Casein kinase II subunit alpha'

2

6

Small-scale

0.571

High

622166

MCM3
DNA replication licensing factor MCM3

2

5

High-throughput

0.571

High

667591

MCM2
DNA replication licensing factor MCM2

2

5

High-throughput

0.571

High

667858

MCM5
Minichromosome maintenance protein 5

2

3

High-throughput

0.571

High

687702

BTAF1
TATA-binding protein-associated factor MOT1

2

8

High-throughput

0.571

High

752914

YHI0
Putative proline--tRNA ligase YHR020W

2

1

High-throughput

0.571

High

757281

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

6

High-throughput

0.571

High

772298

TAF6
Transcription initiation factor TFIID subunit 6

2

1

High-throughput

0.571

High

772340

FKBP4
FK506-binding protein 4

2

6

High-throughput

0.571

High

140783

FOB1
DNA replication fork-blocking protein FOB1

2

0

High-throughput

0.547

High

772307

H1
Histone H1

2

0

High-throughput

0.547

High

772328

IOC4
ISWI one complex protein 4

2

0

High-throughput

0.547

High

772338

SFH1
Chromatin structure-remodeling complex subunit SFH1

2

0

High-throughput

0.547

High

772299

APC10
Anaphase-promoting complex subunit DOC1

1

2

High-throughput

0.541

High

511531

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.536

High

772294

NET1
Nucleolar protein NET1

2

1

High-throughput

0.521

High

772308

COPA
Coatomer subunit alpha

2

6

High-throughput

0.521

High

772318

TOF2
Topoisomerase 1-associated factor 2

2

1

High-throughput

0.521

High

699553

BEM3
GTPase-activating protein BEM3

1

1

High-throughput

0.489

High

560677

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.481

High

655714

PRP45
Pre-mRNA-processing protein 45

1

2

Small-scale

0.481

High

690211

CDC3
Cell division control protein 3

1

2

High-throughput

0.481

High

697218

BRR2
Pre-mRNA-splicing helicase BRR2

1

4

Small-scale

0.481

High

710770

CASP
Protein CASP

1

4

High-throughput

0.481

High

772286

GZF3
Protein GZF3

1

1

High-throughput

0.481

High

772345

HDA2
HDA1 complex subunit 2

1

1

High-throughput

0.481

High

334713

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.479

High

375606

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

7

High-throughput

0.479

High

388108

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.479

High

415997

DED1
ATP-dependent RNA helicase DED1

1

3

High-throughput

0.479

High

429709

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

4

High-throughput

0.479

High

501373

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

7

High-throughput

0.479

High

550050

CSK21
Casein kinase II subunit alpha

1

7

Small-scale

0.479

High

593146

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

Small-scale

0.479

High

599471

VPS1
Vacuolar protein sorting-associated protein 1

1

3

High-throughput

0.479

High

601759

RCC1
Guanine nucleotide exchange factor SRM1

1

3

High-throughput

0.479

High

604565

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

5

High-throughput

0.479

High

606664

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

5

High-throughput

0.479

High

607282

RFA1
Replication factor A protein 1

1

3

High-throughput

0.479

High

662392

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

664865

BMH1
Protein BMH1

1

10

High-throughput

0.479

High

675528

MCM4
DNA replication licensing factor MCM4

1

5

High-throughput

0.479

High

687392

EF2
Elongation factor 2

1

4

High-throughput

0.479

High

688270

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

698829

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

9

High-throughput

0.479

High

699688

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.479

High

703059

MRT4
Ribosome assembly factor MRT4

1

5

High-throughput

0.479

High

728698

BDF1
Bromodomain-containing factor 1

1

13

High-throughput

0.479

High

730819

CENPA
Histone H3-like centromeric protein CSE4

1

14

Small-scale

0.479

High

742829

GBLP
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.479

High

754240

RSC30
Chromatin structure-remodeling complex protein RSC30

1

2

High-throughput

0.479

High

772282

MAM33
Mitochondrial acidic protein MAM33

1

2

High-throughput

0.479

High

772283

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

772295

SMC3
Structural maintenance of chromosomes protein 3

1

1

Small-scale

0.479

High

772302

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

2

High-throughput

0.479

High

772303

NSA1
Ribosome biogenesis protein NSA1

1

2

High-throughput

0.479

High

772310

APJ1
J domain-containing protein APJ1

1

9

High-throughput

0.479

High

772315

ACAC
Acetyl-CoA carboxylase

1

5

High-throughput

0.479

High

772319

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.479

High

772326

HMO1
High mobility group protein 1

1

2

High-throughput

0.479

High

772327

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

772330

DPB4
DNA polymerase epsilon subunit D

1

1

Small-scale

0.479

High

772332

ERB1
Ribosome biogenesis protein ERB1

1

6

High-throughput

0.479

High

772336

SWR1
Helicase SWR1

1

5

High-throughput

0.479

High

772337

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

772348

BDF2
Bromodomain-containing factor 2

1

5

High-throughput

0.479

High

772350

SGO1
Shugoshin

1

2

High-throughput

0.479

High

772352

YTM1
Ribosome biogenesis protein YTM1

1

13

High-throughput

0.479

High

772354

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

772355

PSH1
RING finger protein PSH1

1

4

High-throughput

0.479

High

772356

MAK21
Ribosome biogenesis protein MAK21

1

3

High-throughput

0.479

High

772359

ARP7
Actin-related protein 7

1

3

High-throughput

0.479

High

772360

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

772364

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

772366

SMC6
Structural maintenance of chromosomes protein 6

1

4

High-throughput

0.479

High

702673

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

772293

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.460

High

772344

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

419480

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

604686

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

Small-scale

0.458

High

716257

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

746445

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

755825

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

757134

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

0

High-throughput

0.458

High

772287

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.458

High

772291

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.458

High

772304

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.458

High

772305

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.458

High

772316

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

772343

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

772358

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

772367

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.458

High

366384

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

472576

YL12B
Transposon Ty1-LR2 Gag-Pol polyprotein

1

2

High-throughput

0.445

High

491406

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

494118

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

519951

TCPA
T-complex protein 1 subunit alpha

1

7

High-throughput

0.445

High

543848

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.445

High

633271

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

650306

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.445

High

660917

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

4

High-throughput

0.445

High

678744

RAD16
DNA repair protein RAD16

1

8

High-throughput

0.445

High

690879

HIR2
Protein HIR2

1

6

High-throughput

0.445

High

694812

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.445

High

715806

MDJ1
DnaJ homolog 1, mitochondrial

1

10

High-throughput

0.445

High

744631

TAF5
Transcription initiation factor TFIID subunit 5

1

13

High-throughput

0.445

High

751031

RCK1
Serine/threonine-protein kinase RCK1

1

4

High-throughput

0.445

High

754234

YHL4
Uncharacterized protein YHR054C

1

1

High-throughput

0.445

High

766033

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.445

High

767650

IMB4
Importin subunit beta-4

1

2

High-throughput

0.445

High

768577

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

772296

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.445

High

772300

INO80
Chromatin-remodeling ATPase INO80

1

7

High-throughput

0.445

High

772323

GCN5
Histone acetyltransferase GCN5

1

12

High-throughput

0.445

High

772324

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.445

High

772333

RCO1
Transcriptional regulatory protein RCO1

1

4

High-throughput

0.445

High

772347

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

5

High-throughput

0.445

High

772351

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

6

High-throughput

0.445

High

772362

RLF2
Chromatin assembly factor 1 subunit p90

1

2

High-throughput

0.445

High

440153

ERG20
Farnesyl pyrophosphate synthase

1

1

Small-scale

0.439

High

772341

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

693851

SRP40
Suppressor protein SRP40

1

3

High-throughput

0.437

High

754128

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.437

High

772320

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.437

High

419344

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

554661

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

587858

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.426

High

609096

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

691322

NGG1
Chromatin-remodeling complexes subunit NGG1

1

0

High-throughput

0.426

High

716094

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.426

High

733253

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

752370

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.426

High

772292

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

772297

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

772301

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

772306

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.426

High

685534

COPG
Coatomer subunit gamma

1

5

High-throughput

0.407

High

764845

SNF7
Vacuolar-sorting protein SNF7

1

4

High-throughput

0.407

High

770504

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

8

High-throughput

0.407

High

772284

COPB2
Coatomer subunit beta'

1

6

High-throughput

0.407

High

772285

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

772289

ERJ5
ER-localized J domain-containing protein 5

1

7

High-throughput

0.407

High

772329

PFD5
Prefoldin subunit 5

1

2

High-throughput

0.407

High

772309

SNZ2
Probable pyridoxal 5'-phosphate synthase subunit SNZ2

2

0

High-throughput

0.298

High

629733

STE50
Protein STE50

1

0

High-throughput

0.251

Low

767881

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.251

Low

772314

DID2
Vacuolar protein-sorting-associated protein 46

1

0

High-throughput

0.232

Low

772334

SNO4
Probable glutathione-independent glyoxalase SNO4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024