Protein: METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) (Cobalamin-independent methionine synthase) (Delta-P8 protein) (Methionine synthase, vitamin-B12 independent isozyme)

Gene: METE, MET6
Organism: Saccharomyces cerevisiae S288C
Interactions: 123
UniProt ID: P05694

Gene Ontology (top 5):
GO:0003871 - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

404304

SIS1
Protein SIS1

2

1

High-throughput

0.588

High

365532

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.584

High

404295

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

404350

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

404289

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

404290

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

404345

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

404313

CDC12
Cell division control protein 12

1

0

High-throughput

0.513

High

404342

RSP5
E3 ubiquitin-protein ligase RSP5

1

1

Small-scale

0.501

High

404352

ENT3
Epsin-3

1

1

Small-scale

0.501

High

404371

ENT5
Epsin-5

1

1

Small-scale

0.501

High

404293

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

1

High-throughput

0.500

High

404376

IMB1
Importin subunit beta-1

1

0

High-throughput

0.493

High

404379

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

0

High-throughput

0.493

High

404294

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.479

High

404296

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.479

High

404298

GBB
Guanine nucleotide-binding protein subunit beta

1

0

High-throughput

0.479

High

404301

FKBP
FK506-binding protein 1

1

0

High-throughput

0.479

High

404303

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.479

High

404305

MSH3
DNA mismatch repair protein MSH3

1

0

High-throughput

0.479

High

404308

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.479

High

404312

CDC3
Cell division control protein 3

1

0

High-throughput

0.479

High

404314

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.479

High

404315

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.479

High

404316

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.479

High

404323

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.479

High

404328

VPS21
Vacuolar protein sorting-associated protein 21

1

0

High-throughput

0.479

High

404340

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.479

High

404341

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

0

High-throughput

0.479

High

404349

RIM15
Serine/threonine-protein kinase RIM15

1

0

High-throughput

0.479

High

404353

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.479

High

404360

RHO4
GTP-binding protein RHO4

1

0

High-throughput

0.479

High

404361

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.479

High

404365

IMA1
Importin subunit alpha

1

0

High-throughput

0.479

High

404369

STE20
Serine/threonine-protein kinase STE20

1

0

High-throughput

0.479

High

404378

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.479

High

404382

CDC53
Cell division control protein 53

1

0

High-throughput

0.479

High

404383

ATG5
Autophagy protein 5

1

0

High-throughput

0.479

High

334399

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

334571

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

334858

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.479

High

340572

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.479

High

342607

ENO1
Enolase 1

1

1

High-throughput

0.479

High

342805

ENO2
Enolase 2

1

1

High-throughput

0.479

High

404318

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

404368

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

141034

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

343321

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

343479

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.458

High

382832

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

389181

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

404278

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

404279

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

404280

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

404281

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

404282

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

404285

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

404286

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

404287

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

404291

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

404292

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

404297

MDHM
Malate dehydrogenase, mitochondrial

1

0

Small-scale

0.458

High

404306

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

404309

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

404311

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

404319

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

404321

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

404322

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

404325

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

404326

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

404329

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

404330

RMD9L
RNA-binding protein RMD9-like, mitochondrial

1

0

High-throughput

0.458

High

404332

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

404333

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

404334

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

404336

MET30
F-box protein MET30

1

0

High-throughput

0.458

High

404338

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

404339

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

404344

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

404347

EGH1
Ergosteryl-beta-glucosidase

1

0

High-throughput

0.458

High

404348

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.458

High

404357

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

404362

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

404366

ESP1
Separin

1

0

High-throughput

0.458

High

404367

COFI
Cofilin

1

0

High-throughput

0.458

High

404380

SGO1
Shugoshin

1

0

High-throughput

0.458

High

404384

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

404284

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

404288

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

404337

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

404343

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

404375

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.445

High

404307

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

404354

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

404327

LHS1
Heat shock protein 70 homolog LHS1

1

3

High-throughput

0.407

High

404385

SMC6
Structural maintenance of chromosomes protein 6

2

0

High-throughput

0.310

High

404351

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.279

Low

404363

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.279

Low

404373

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.279

Low

404374

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

355725

H2B2
Histone H2B.2

1

0

High-throughput

0.269

Low

404283

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.261

Low

404299

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.261

Low

404300

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

0

High-throughput

0.261

Low

404302

DBF2
Cell cycle protein kinase DBF2

1

0

High-throughput

0.261

Low

404317

CDC13
Cell division control protein 13

1

0

High-throughput

0.261

Low

404320

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

404335

TEM1
Protein TEM1

1

0

High-throughput

0.261

Low

404355

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.261

Low

404364

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

375191

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

388070

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.249

Low

404310

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

404324

IXR1
Intrastrand cross-link recognition protein

1

0

Small-scale

0.249

Low

404331

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

404346

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

404356

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.249

Low

404359

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

404370

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low

404372

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

404377

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

404381

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

404358

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024