Protein: NOT3
General negative regulator of transcription subunit 3

Gene: NOT3
Organism: Saccharomyces cerevisiae S288C
Interactions: 125
UniProt ID: P06102

Gene Ontology (top 5):
GO:0000289 - nuclear-transcribed mRNA poly(A) tail shortening
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

409955

NOT1
General negative regulator of transcription subunit 1

11

4

Small-scale

0.972

High

409814

NOT2
General negative regulator of transcription subunit 2

6

8

Small-scale

0.943

High

410041

NOT5
General negative regulator of transcription subunit 5

5

2

Small-scale

0.921

High

409979

NOT4
General negative regulator of transcription subunit 4

10

2

Small-scale

0.751

High

410018

CAF40
Protein CAF40

7

4

Small-scale

0.747

High

409992

POP2
Poly(A) ribonuclease POP2

4

6

Small-scale

0.693

High

409961

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

3

6

Small-scale

0.658

High

410031

WHI4
Protein WHI4

2

1

High-throughput

0.608

High

410037

YRA1
RNA annealing protein YRA1

2

1

High-throughput

0.588

High

410007

TAF1
Transcription initiation factor TFIID subunit 1

2

1

Small-scale

0.586

High

409926

PDC1
Pyruvate decarboxylase isozyme 1

2

0

High-throughput

0.563

High

409936

METK1
S-adenosylmethionine synthase 1

2

0

High-throughput

0.563

High

410040

AHA1
Hsp90 co-chaperone AHA1

2

0

High-throughput

0.563

High

409934

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

409935

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

409938

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.552

High

409978

WHI3
Protein WHI3

1

1

High-throughput

0.541

High

410021

NST1
Stress response protein NST1

1

1

High-throughput

0.541

High

409957

RL16A
Large ribosomal subunit protein uL13A

2

1

High-throughput

0.521

High

409986

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.518

High

410011

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

1

High-throughput

0.515

High

410023

NACB1
Nascent polypeptide-associated complex subunit beta-1

1

2

Small-scale

0.508

High

409941

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.501

High

409977

HSL1
Probable serine/threonine-protein kinase HSL1

1

1

High-throughput

0.501

High

409965

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

1

High-throughput

0.494

High

409999

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

0

High-throughput

0.486

High

409927

KAPB
cAMP-dependent protein kinase type 2

1

1

Small-scale

0.481

High

409939

TAF13
Transcription initiation factor TFIID subunit 13

1

1

Small-scale

0.481

High

409943

TUP1
General transcriptional corepressor TUP1

1

1

High-throughput

0.481

High

409946

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

1

Small-scale

0.481

High

409948

KIN3
Serine/threonine-protein kinase KIN3

1

2

High-throughput

0.481

High

409954

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

Small-scale

0.481

High

409974

NIP80
Protein NIP100

1

1

High-throughput

0.481

High

409991

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.481

High

410003

MAD1
Spindle assembly checkpoint component MAD1

1

1

High-throughput

0.481

High

410019

CNM67
Chaotic nuclear migration protein 67

1

1

High-throughput

0.481

High

409950

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.480

High

408211

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

409931

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.479

High

409932

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

2

High-throughput

0.479

High

409940

TBP
TATA-box-binding protein

1

1

High-throughput

0.479

High

409958

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

409970

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

409973

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

409980

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

409988

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.479

High

410001

TM108
Protein TMA108

1

1

High-throughput

0.479

High

410024

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

410035

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

410036

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

409945

MYO2
Myosin-2

1

0

High-throughput

0.460

High

409964

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.460

High

409972

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

409982

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.460

High

409983

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

409987

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.460

High

409996

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.460

High

409997

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.460

High

410006

BUD27
Bud site selection protein 27

1

0

High-throughput

0.460

High

410008

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

0

High-throughput

0.460

High

410014

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

410020

CBK1
Serine/threonine-protein kinase CBK1

1

0

Small-scale

0.460

High

410029

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

410030

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

410033

SLK19
Kinetochore protein SLK19

1

0

High-throughput

0.460

High

410034

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.460

High

409959

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

409963

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

409981

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.458

High

409984

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

410002

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

410010

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

410027

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

410028

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

410038

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

367597

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

399258

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

409928

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.445

High

409942

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

409952

GBP2
Serine/arginine

1

2

High-throughput

0.445

High

409962

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

409967

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

409968

HSP79
Heat shock protein homolog SSE2

1

7

High-throughput

0.445

High

409989

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

410000

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

410005

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

410013

KEL2
Kelch repeat-containing protein 2

1

1

High-throughput

0.439

High

410022

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.439

High

409985

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

409971

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

141047

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.426

High

404446

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

405093

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.426

High

407613

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.426

High

409929

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

409930

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

409937

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

409947

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.426

High

409951

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

409956

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

410004

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

409944

FAS2
Fatty acid synthase subunit alpha

2

0

High-throughput

0.307

High

409953

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

409960

ZIP1
Synaptonemal complex protein ZIP1

1

0

High-throughput

0.251

Low

409966

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

409969

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

409976

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

409990

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

409995

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

409998

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

410009

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

410012

NUP57
Nucleoporin NUP57

1

0

High-throughput

0.251

Low

410015

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.251

Low

410016

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

410017

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

410025

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

410026

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

410032

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

410039

RUD3
GRIP domain-containing protein RUD3

1

0

High-throughput

0.251

Low

410042

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

409975

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.249

Low

409994

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

409933

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.232

Low

409949

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.232

Low

409993

RS14B
Small ribosomal subunit protein uS11B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024