Protein: ILVB
Acetolactate synthase catalytic subunit, mitochondrial (EC 2.2.1.6) (Acetohydroxy-acid synthase catalytic subunit) (AHAS) (ALS)

Gene: ILVB, ILV2
Organism: Saccharomyces cerevisiae S288C
Interactions: 191
UniProt ID: P07342

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003984 - acetolactate synthase activity
GO:0005739 - mitochondrion
GO:0005948 - acetolactate synthase complex
GO:0008652 - amino acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427189

ILV6
Acetolactate synthase small subunit, mitochondrial

4

4

Small-scale

0.899

High

427182

SIS1
Protein SIS1

3

3

High-throughput

0.587

High

427155

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.584

High

427170

MDHM
Malate dehydrogenase, mitochondrial

2

1

Small-scale

0.584

High

427254

SSB2
Ribosome-associated molecular chaperone SSB2

3

9

High-throughput

0.579

High

427149

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

16

Small-scale

0.575

High

343066

THDH
Threonine dehydratase, mitochondrial

2

1

High-throughput

0.571

High

427167

HSC82
ATP-dependent molecular chaperone HSC82

2

8

High-throughput

0.571

High

427160

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

427232

GBLP
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.543

High

427279

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

427284

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

365590

HSP82
ATP-dependent molecular chaperone HSP82

2

8

High-throughput

0.533

High

406662

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.521

High

427216

RSSA1
Small ribosomal subunit protein uS2A

2

6

High-throughput

0.521

High

427159

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.504

High

427163

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.504

High

427176

MDHC
Malate dehydrogenase, cytoplasmic

1

1

High-throughput

0.500

High

427208

EI2BB
Translation initiation factor eIF2B subunit beta

1

3

High-throughput

0.500

High

427222

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.493

High

427280

TEP1
Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1

1

1

High-throughput

0.489

High

427295

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.489

High

341883

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

427158

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

427171

ACON
Aconitate hydratase, mitochondrial

1

2

High-throughput

0.479

High

427172

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.479

High

427174

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

427185

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

1

High-throughput

0.479

High

427193

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

1

High-throughput

0.479

High

427198

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

2

High-throughput

0.479

High

427223

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.479

High

427233

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

1

High-throughput

0.479

High

427248

SYPM
Probable proline--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

427252

ALDH5
Aldehyde dehydrogenase 5, mitochondrial

1

2

High-throughput

0.479

High

427264

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

427265

DLD2
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2

1

2

High-throughput

0.479

High

427274

LYS4
Homoaconitase, mitochondrial

1

2

High-throughput

0.479

High

427283

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

427291

RT10
Small ribosomal subunit protein uS10m

1

2

High-throughput

0.479

High

427307

NEW1
[NU+] prion formation protein 1

1

2

High-throughput

0.479

High

427313

RM23
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.479

High

427316

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

427150

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

1

High-throughput

0.470

High

427315

YP247
WD repeat-containing protein YPL247C

1

1

High-throughput

0.470

High

410732

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

423556

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.458

High

424160

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.458

High

427162

RT02
Small ribosomal subunit protein uS14m

1

0

High-throughput

0.458

High

427169

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

427175

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.458

High

427180

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.458

High

427190

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.458

High

427197

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

0

High-throughput

0.458

High

427199

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.458

High

427205

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.458

High

427213

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

427214

PREP
Presequence protease, mitochondrial

1

0

High-throughput

0.458

High

427215

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.458

High

427226

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

427228

PMIP
Mitochondrial intermediate peptidase

1

0

High-throughput

0.458

High

427229

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.458

High

427231

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

427234

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.458

High

427236

GRPE
GrpE protein homolog, mitochondrial

1

0

High-throughput

0.458

High

427240

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

427243

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

427253

AIM9
Altered inheritance of mitochondria protein 9, mitochondrial

1

0

High-throughput

0.458

High

427256

COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial

1

0

High-throughput

0.458

High

427262

RT18
Small ribosomal subunit protein uS11m

1

0

High-throughput

0.458

High

427263

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

427268

CAF17
Putative transferase CAF17, mitochondrial

1

0

High-throughput

0.458

High

427269

GCST
Aminomethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

427272

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

High-throughput

0.458

High

427273

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

427275

ALAM
Probable alanine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

427287

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

427288

RT51
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.458

High

427289

ESP1
Separin

1

0

High-throughput

0.458

High

427290

ISU1
Iron sulfur cluster assembly protein 1, mitochondrial

1

0

High-throughput

0.458

High

427297

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

427300

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

427305

ETFD
Probable electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.458

High

427312

ETFA
Probable electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

427164

EI2BD
Translation initiation factor eIF2B subunit delta

1

3

High-throughput

0.457

High

427173

PP11
Serine/threonine-protein phosphatase PP1-1

1

1

High-throughput

0.457

High

427181

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

2

High-throughput

0.457

High

427183

CDC10
Cell division control protein 10

1

1

High-throughput

0.457

High

427184

RV161
Reduced viability upon starvation protein 161

1

2

High-throughput

0.457

High

427187

DMC1
Meiotic recombination protein DMC1

1

2

High-throughput

0.457

High

427194

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

4

High-throughput

0.457

High

427204

ARP2
Actin-related protein 2

1

1

High-throughput

0.457

High

427207

MKK2
MAP kinase kinase MKK2/SSP33

1

1

High-throughput

0.457

High

427209

RPD3
Histone deacetylase RPD3

1

1

Small-scale

0.457

High

427221

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

2

High-throughput

0.457

High

427235

IMB2
Importin subunit beta-2

1

1

High-throughput

0.457

High

427241

PEX7
Peroxisomal targeting signal 2 receptor

1

2

High-throughput

0.457

High

427247

SLN1
Osmosensing histidine protein kinase SLN1

1

1

High-throughput

0.457

High

427258

COPB2
Coatomer subunit beta'

1

4

High-throughput

0.457

High

427276

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.457

High

427277

SSK2
MAP kinase kinase kinase SSK2

1

1

High-throughput

0.457

High

427278

COPA
Coatomer subunit alpha

1

4

High-throughput

0.457

High

427293

WDR59
Maintenance of telomere capping protein 5

1

5

High-throughput

0.457

High

427296

SPC24
Kinetochore protein SPC24

1

1

High-throughput

0.457

High

427298

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

2

High-throughput

0.457

High

427314

SKS1
Serine/threonine-protein kinase SKS1

1

1

High-throughput

0.457

High

427317

AP2M
AP-2 complex subunit mu

1

2

High-throughput

0.457

High

339969

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

367621

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

424278

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

427151

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.445

High

427218

UFD4
Ubiquitin fusion degradation protein 4

1

2

High-throughput

0.445

High

427225

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.445

High

427230

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

2

High-throughput

0.445

High

427250

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

427308

MDN1
Midasin

1

1

High-throughput

0.445

High

427178

SAN1
Protein SAN1

1

1

Small-scale

0.439

High

141062

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

357786

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

382858

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

402841

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

2

Small-scale

0.437

High

405333

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

407626

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.437

High

413211

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

425665

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

427153

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

427154

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

427156

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

427157

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

427165

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

427186

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.437

High

427196

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

427200

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

427217

SMY2
Protein SMY2

1

2

High-throughput

0.437

High

427224

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

427227

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.437

High

427237

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.437

High

427242

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.437

High

427244

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

427251

ARB1
ABC transporter ATP-binding protein ARB1

1

1

Small-scale

0.437

High

427255

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.437

High

427266

MPS3
Spindle pole body assembly component MPS3

1

4

High-throughput

0.437

High

427267

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.437

High

427270

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High

427271

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

427285

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

427286

MLP1
Protein MLP1

1

2

High-throughput

0.437

High

427304

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

427306

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.437

High

421543

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

427245

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.426

High

427282

DNM1
Dynamin-related protein DNM1

1

0

High-throughput

0.426

High

360696

TBB
Tubulin beta chain

1

1

High-throughput

0.407

High

427161

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.407

High

427168

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.407

High

427177

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

2

High-throughput

0.407

High

427201

HS104
Heat shock protein 104

1

5

High-throughput

0.407

High

427210

RPN2
26S proteasome regulatory subunit RPN2

1

3

High-throughput

0.407

High

427211

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.407

High

427212

HSP79
Heat shock protein homolog SSE2

1

16

High-throughput

0.407

High

427238

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.407

High

427239

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.407

High

427260

MPG1
Mannose-1-phosphate guanyltransferase

1

4

High-throughput

0.407

High

427261

EMW1
Essential for maintenance of the cell wall protein 1

1

1

High-throughput

0.407

High

427310

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.279

Low

427179

UBA1
Ubiquitin-activating enzyme E1 1

1

0

High-throughput

0.269

Low

427301

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.269

Low

427249

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.261

Low

427311

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.261

Low

427188

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.249

Low

427191

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

427203

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

427206

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

427259

MID1
Stretch-activated cation channel MID1

1

0

Small-scale

0.249

Low

427281

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

427294

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

427299

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

427302

YD053
Putative uncharacterized protein YDR053W

1

0

High-throughput

0.249

Low

427303

MCA1
Metacaspase-1

1

0

High-throughput

0.249

Low

427309

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.249

Low

399269

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

427152

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.232

Low

427166

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

427192

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

427195

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

427202

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

427219

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.232

Low

427220

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

High-throughput

0.232

Low

427246

NPR2
Nitrogen permease regulator 2

1

0

High-throughput

0.232

Low

427257

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low

427292

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024