Protein: ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)

Gene: ODP2, LAT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 146
UniProt ID: P12695

Gene Ontology (top 5):
GO:0004742 - dihydrolipoyllysine-residue acetyltransferase activity
GO:0005739 - mitochondrion
GO:0006086 - acetyl-CoA biosynthetic process from pyruvate

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520802

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

5

8

High-throughput

0.922

High

520782

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

4

11

High-throughput

0.892

High

452941

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

2

12

High-throughput

0.754

High

520783

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

2

14

High-throughput

0.754

High

520792

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

3

2

High-throughput

0.660

High

520808

PREP
Presequence protease, mitochondrial

2

8

High-throughput

0.621

High

520785

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

14

High-throughput

0.618

High

520844

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

424308

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.575

High

493047

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

520801

HS104
Heat shock protein 104

2

4

Small-scale

0.533

High

520809

RSSA1
Small ribosomal subunit protein uS2A

2

1

High-throughput

0.521

High

490160

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.504

High

500294

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

1

High-throughput

0.500

High

520787

FKBP
FK506-binding protein 1

1

1

High-throughput

0.500

High

520838

RSP5
E3 ubiquitin-protein ligase RSP5

1

5

High-throughput

0.500

High

520824

TYDP1
Tyrosyl-DNA phosphodiesterase 1

1

0

High-throughput

0.479

High

520831

MLH1
DNA mismatch repair protein MLH1

1

0

High-throughput

0.479

High

367522

EFTU
Elongation factor Tu, mitochondrial

1

6

High-throughput

0.479

High

429164

SEC4
Ras-related protein SEC4

1

3

Small-scale

0.479

High

482035

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

520786

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

520807

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

520812

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

520818

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

520835

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

1

High-throughput

0.479

High

520861

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

520873

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

520890

SMC6
Structural maintenance of chromosomes protein 6

1

4

High-throughput

0.479

High

520828

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.458

High

520830

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

Small-scale

0.458

High

520850

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

477093

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.457

High

339391

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.457

High

412508

CDC7
Cell division control protein 7

1

4

High-throughput

0.457

High

520776

KSS1
Mitogen-activated protein kinase KSS1

1

2

High-throughput

0.457

High

520778

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

520779

ABP1
Actin-binding protein

1

3

High-throughput

0.457

High

520788

DBF2
Cell cycle protein kinase DBF2

1

4

High-throughput

0.457

High

520799

RAD16
DNA repair protein RAD16

1

3

High-throughput

0.457

High

520800

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

2

High-throughput

0.457

High

520806

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

7

High-throughput

0.457

High

520823

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.457

High

520832

TEM1
Protein TEM1

1

8

High-throughput

0.457

High

520834

PEX7
Peroxisomal targeting signal 2 receptor

1

6

High-throughput

0.457

High

520841

FKH1
Fork head protein homolog 1

1

2

High-throughput

0.457

High

520853

BOL2
BolA-like protein 2

1

1

High-throughput

0.457

High

520855

BUD32
EKC/KEOPS complex subunit BUD32

1

1

High-throughput

0.457

High

520859

IPI3
Pre-rRNA-processing protein IPI3

1

6

High-throughput

0.457

High

520863

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.457

High

520865

COFI
Cofilin

1

1

High-throughput

0.457

High

520887

LAS17
Proline-rich protein LAS17

1

3

High-throughput

0.457

High

367670

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

520842

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.445

High

357838

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

405385

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

406722

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

413259

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

425715

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

470814

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

471979

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

479879

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

520781

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

520793

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

520796

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

520797

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.437

High

520814

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

520817

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.437

High

520819

NOP4
Nucleolar protein 4

1

1

High-throughput

0.437

High

520820

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.437

High

520826

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

520837

RCY1
Recyclin-1

1

1

High-throughput

0.437

High

520848

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

520857

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

520862

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.437

High

520864

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

520866

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.437

High

520867

ESC1
Silent chromatin protein ESC1

1

1

High-throughput

0.437

High

520870

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

520878

SEC10
Exocyst complex component SEC10

1

1

Small-scale

0.437

High

520882

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

520886

ARP8
Actin-like protein ARP8

1

2

High-throughput

0.437

High

520888

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.437

High

520889

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.437

High

339987

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.407

High

360712

TBB
Tubulin beta chain

1

3

High-throughput

0.407

High

454147

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.407

High

510070

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.407

High

520780

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

520784

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.407

High

520791

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.407

High

520829

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.407

High

520840

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.407

High

520843

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

520880

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.407

High

520816

UBX1
UBX domain-containing protein 1

2

0

Small-scale

0.318

High

520775

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.310

High

516834

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.261

Low

520777

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

High-throughput

0.261

Low

520790

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

High-throughput

0.261

Low

520794

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.261

Low

520798

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.261

Low

520805

GYP6
GTPase-activating protein GYP6

1

0

High-throughput

0.261

Low

520821

AP3M
AP-3 complex subunit mu

1

0

High-throughput

0.261

Low

520825

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

0

High-throughput

0.261

Low

520851

RL37B
Large ribosomal subunit protein eL37B

1

0

High-throughput

0.261

Low

520854

PESC
Pescadillo homolog

1

0

High-throughput

0.261

Low

520856

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.261

Low

520860

DMA2
E3 ubiquitin-protein ligase DMA2

1

0

High-throughput

0.261

Low

520883

DDC1
DNA damage checkpoint protein 1

1

0

High-throughput

0.261

Low

141114

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

252687

MRP10
Small ribosomal subunit protein mS37

1

0

High-throughput

0.249

Low

399303

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.249

Low

407679

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

515097

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.249

Low

520789

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

520795

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

520803

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

520804

IES6
Chromatin-remodeling complex subunit IES6

1

0

High-throughput

0.249

Low

520810

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

520813

SPC29
Spindle pole component 29

1

0

High-throughput

0.249

Low

520815

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.249

Low

520822

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

520827

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

520836

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

520846

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

520847

HGH1
Protein HGH1

1

0

Small-scale

0.249

Low

520849

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

520852

NBP1
NAP1-binding protein

1

0

High-throughput

0.249

Low

520869

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

520871

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

520872

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.249

Low

520876

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

520877

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.249

Low

520879

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

520881

ENB1
Siderophore iron transporter ENB1

1

0

High-throughput

0.249

Low

520884

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

High-throughput

0.249

Low

520885

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

520811

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.232

Low

520833

MNN9
Mannan polymerase complexes subunit MNN9

1

0

High-throughput

0.232

Low

520839

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.232

Low

520845

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low

520858

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.232

Low

520868

YMB8
Uncharacterized vacuolar membrane protein YML018C

1

0

High-throughput

0.232

Low

520874

YD338
Uncharacterized transporter YDR338C

1

0

High-throughput

0.232

Low

520875

NSE3
Non-structural maintenance of chromosome element 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024