Protein: VPS1
Vacuolar protein sorting-associated protein 1

Gene: VPS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 174
UniProt ID: P21576

Gene Ontology (top 5):
GO:0000266 - mitochondrial fission
GO:0000329 - fungal-type vacuole membrane
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

599539

VAM3
Syntaxin VAM3

3

0

Small-scale

0.651

High

577126

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

2

9

High-throughput

0.621

High

599431

BTAF1
TATA-binding protein-associated factor MOT1

2

5

High-throughput

0.621

High

599436

CHD1
Chromo domain-containing protein 1

2

1

High-throughput

0.621

High

599508

MSH6
DNA mismatch repair protein MSH6

2

1

High-throughput

0.621

High

599466

RV167
Reduced viability upon starvation protein 167

2

20

Small-scale

0.619

High

599416

VPS1
Vacuolar protein sorting-associated protein 1

1

19

Small-scale

0.618

High

599482

ATG36
Autophagy-related protein 36

2

1

Small-scale

0.609

High

599544

ATG11
Autophagy-related protein 11

3

1

Small-scale

0.606

High

599480

TAF1
Transcription initiation factor TFIID subunit 1

2

0

High-throughput

0.595

High

599537

ATG9
Autophagy-related protein 9

2

0

Small-scale

0.593

High

599429

RAD16
DNA repair protein RAD16

2

4

High-throughput

0.567

High

599454

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

3

High-throughput

0.567

High

599505

NHP10
Non-histone protein 10

2

4

High-throughput

0.567

High

599433

RPD3
Histone deacetylase RPD3

2

0

High-throughput

0.563

High

599485

RFX1
RFX-like DNA-binding protein RFX1

2

0

High-throughput

0.563

High

599497

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.563

High

599437

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

3

Small-scale

0.552

High

493196

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

355774

H2B2
Histone H2B.2

2

2

High-throughput

0.537

High

514233

NHP6B
Non-histone chromosomal protein 6B

2

4

High-throughput

0.537

High

539223

YAK1
Dual specificity protein kinase YAK1

1

11

High-throughput

0.536

High

599434

STH1
Nuclear protein STH1/NPS1

1

4

High-throughput

0.536

High

599492

ARP5
Actin-related protein 5

1

4

High-throughput

0.536

High

599499

ABF2
ARS-binding factor 2, mitochondrial

1

4

High-throughput

0.536

High

599504

GCN5
Histone acetyltransferase GCN5

1

6

High-throughput

0.536

High

599509

HMO1
High mobility group protein 1

1

5

High-throughput

0.536

High

599506

INP1
Inheritance of peroxisomes protein 1

1

0

Small-scale

0.527

High

599422

SIS1
Protein SIS1

1

2

High-throughput

0.515

High

425294

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

431340

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

579767

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.513

High

599489

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

565451

PHO85
Cyclin-dependent protein kinase PHO85

1

3

Small-scale

0.501

High

599494

ACT
Actin

1

2

Small-scale

0.501

High

599528

RTC1
Restriction of telomere capping protein 1

1

5

High-throughput

0.500

High

355343

H2B1
Histone H2B.1

1

2

High-throughput

0.489

High

599542

ARP7
Actin-related protein 7

1

4

High-throughput

0.489

High

599417

CLH
Clathrin heavy chain

1

2

Small-scale

0.481

High

599442

SNC2
Synaptobrevin homolog 2

1

2

Small-scale

0.481

High

599450

VPS24
Vacuolar protein-sorting-associated protein 24

1

6

Small-scale

0.481

High

599546

YPT6
GTP-binding protein YPT6

1

2

Small-scale

0.481

High

599519

NAT3
N-terminal acetyltransferase B complex catalytic subunit NAT3

1

0

Small-scale

0.480

High

365788

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

477122

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

11

High-throughput

0.479

High

477596

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

5

High-throughput

0.479

High

477897

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.479

High

485645

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.479

High

503046

ARF1
ADP-ribosylation factor 1

1

2

High-throughput

0.479

High

543192

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

593737

DBP5
ATP-dependent RNA helicase DBP5

1

2

High-throughput

0.479

High

595768

VPS33
Vacuolar protein sorting-associated protein 33

1

2

Small-scale

0.479

High

599418

VPS15
Serine/threonine-protein kinase VPS15

1

3

High-throughput

0.479

High

599420

RFA1
Replication factor A protein 1

1

3

Small-scale

0.479

High

599423

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

599428

XPO1
Exportin-1

1

2

High-throughput

0.479

High

599430

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

599438

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

4

High-throughput

0.479

High

599440

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

599443

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.479

High

599449

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

599457

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

599463

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

599467

IMB4
Importin subunit beta-4

1

4

High-throughput

0.479

High

599471

ATAD2
ATPase histone chaperone YTA7

1

3

High-throughput

0.479

High

599473

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.479

High

599475

MVP1
Sorting nexin MVP1

1

14

Small-scale

0.479

High

599477

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.479

High

599479

ATG18
Autophagy-related protein 18

1

2

High-throughput

0.479

High

599487

ATG1
Serine/threonine-protein kinase ATG1

1

3

High-throughput

0.479

High

599488

CDH1
APC/C activator protein CDH1

1

4

Small-scale

0.479

High

599490

ATG2
Autophagy-related protein 2

1

1

High-throughput

0.479

High

599491

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

599493

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.479

High

599496

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.479

High

599500

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.479

High

599510

SXM1
Importin beta SMX1

1

1

High-throughput

0.479

High

599511

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

599516

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

599517

IMB1
Importin subunit beta-1

1

3

High-throughput

0.479

High

599534

AP3D
AP-3 complex subunit delta

1

9

High-throughput

0.479

High

599538

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

599540

TPO4
Polyamine transporter 4

1

1

High-throughput

0.479

High

599452

VPS51
Vacuolar protein sorting-associated protein 51

1

0

Small-scale

0.460

High

599512

VTI1
t-SNARE VTI1

1

0

Small-scale

0.460

High

599524

VPS36
Vacuolar protein-sorting-associated protein 36

1

0

Small-scale

0.460

High

599526

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

Small-scale

0.460

High

599543

SNF8
Vacuolar-sorting protein SNF8

1

0

Small-scale

0.460

High

141152

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

375275

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

382951

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

406784

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

413303

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

425765

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

479921

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

480482

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

524165

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

541518

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.458

High

599421

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.458

High

599425

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

599441

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

599444

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

599448

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

599451

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

599453

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

599458

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

599459

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.458

High

599461

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

599462

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

599465

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

599469

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

599474

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

599476

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

599483

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

599484

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

599498

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

599501

IMA1
Importin subunit alpha

1

0

High-throughput

0.458

High

599502

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

599503

ESP1
Separin

1

0

High-throughput

0.458

High

599520

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.458

High

599525

CSR1
Phosphatidylinositol transfer protein CSR1

1

0

High-throughput

0.458

High

599529

SGO1
Shugoshin

1

0

High-throughput

0.458

High

599530

PEX27
Peroxisomal membrane protein PEX27

1

0

Small-scale

0.458

High

599531

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

599532

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

599535

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

599536

ATG29
Autophagy-related protein 29

1

0

High-throughput

0.458

High

367739

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

454178

TBA1
Tubulin alpha-1 chain

1

4

High-throughput

0.445

High

490333

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

510254

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

599427

MCM5
Minichromosome maintenance protein 5

1

1

High-throughput

0.445

High

599445

MSN2
Zinc finger protein MSN2

1

3

High-throughput

0.445

High

599446

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.445

High

599447

SPT7
Transcriptional activator SPT7

1

5

High-throughput

0.445

High

599468

MGDP1
Putative magnesium-dependent phosphatase YER134C

1

1

High-throughput

0.445

High

599470

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

599481

NMD5
Nonsense-mediated mRNA decay protein 5

1

4

High-throughput

0.445

High

599486

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.445

High

392290

H2A2
Histone H2A.2

1

3

High-throughput

0.437

High

599419

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

599426

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

599456

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

599495

H3
Histone H3

1

4

High-throughput

0.437

High

599513

SEC13
Protein transport protein SEC13

1

1

High-throughput

0.437

High

599533

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.437

High

515037

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

599435

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.426

High

599455

SEA4
SEH-associated protein 4

1

0

High-throughput

0.426

High

599460

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.426

High

599464

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

599523

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.426

High

514144

NHP6A
Non-histone chromosomal protein 6A

1

4

High-throughput

0.407

High

599439

PDC2
Protein PDC2

1

1

High-throughput

0.407

High

599514

RCO1
Transcriptional regulatory protein RCO1

1

2

High-throughput

0.407

High

526946

TBP
TATA-box-binding protein

2

0

High-throughput

0.324

High

599233

REB1
DNA-binding protein REB1

2

0

High-throughput

0.324

High

452070

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.279

Low

599478

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.279

Low

599507

TAF12
Transcription initiation factor TFIID subunit 12

1

0

High-throughput

0.279

Low

599521

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.279

Low

599541

IES3
Ino eighty subunit 3

1

0

High-throughput

0.279

Low

599424

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

599432

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

599518

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

599522

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

599547

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

535749

ABF1
ARS-binding factor 1

1

0

High-throughput

0.232

Low

599472

DLS1
Protein DLS1

1

0

High-throughput

0.232

Low

599515

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.232

Low

599527

THP1
Nuclear mRNA export protein THP1

1

0

High-throughput

0.232

Low

599545

NCB2
Negative cofactor 2 complex subunit beta

1

0

High-throughput

0.232

Low

599548

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024