Protein: RL8A
Large ribosomal subunit protein eL8A (60S ribosomal protein L8-A) (L4) (L4-2) (L7a-1) (Maintenance of killer protein 7) (RP6) (YL5)

Gene: RL8A, RPL8A
Organism: Saccharomyces cerevisiae S288C
Interactions: 244
UniProt ID: P17076

Gene Ontology (top 5):
GO:0000470 - maturation of LSU-rRNA
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

564239

RL8B
Large ribosomal subunit protein eL8B

2

4

High-throughput

0.754

High

564335

PESC
Pescadillo homolog

2

2

Small-scale

0.754

High

564286

NMD3
60S ribosomal export protein NMD3

8

1

Small-scale

0.744

High

564399

IF6
Eukaryotic translation initiation factor 6

4

1

Small-scale

0.676

High

564364

ARX1
Probable metalloprotease ARX1

6

2

Small-scale

0.658

High

564330

LSG1
Large subunit GTPase 1

3

6

Small-scale

0.650

High

564266

RPF2
Ribosome biogenesis protein RPF2

5

4

Small-scale

0.645

High

564342

NOG2
Nucleolar GTP-binding protein 2

5

6

Small-scale

0.641

High

564384

BRX1
Ribosome biogenesis protein BRX1

3

16

Small-scale

0.640

High

141133

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.618

High

145696

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.618

High

406287

RL15A
Large ribosomal subunit protein eL15A

1

2

High-throughput

0.618

High

407702

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.618

High

408263

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.618

High

471735

RL27A
Large ribosomal subunit protein eL27A

1

4

High-throughput

0.618

High

471875

RL27B
Large ribosomal subunit protein eL27B

1

4

High-throughput

0.618

High

479061

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.618

High

481111

RL1A
Large ribosomal subunit protein uL1A

1

5

High-throughput

0.618

High

534690

RL30
Large ribosomal subunit protein eL30

1

3

High-throughput

0.618

High

564222

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.618

High

564269

GBLP
Small ribosomal subunit protein RACK1

1

12

High-throughput

0.618

High

564282

CIC1
Proteasome-interacting protein CIC1

1

2

Small-scale

0.618

High

564308

RL34B
Large ribosomal subunit protein eL34B

1

5

High-throughput

0.618

High

564323

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.618

High

564350

RL34A
Large ribosomal subunit protein eL34A

1

5

High-throughput

0.618

High

564387

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.618

High

564295

NOC2
Nucleolar complex protein 2

4

2

Small-scale

0.617

High

365742

HSP82
ATP-dependent molecular chaperone HSP82

3

0

High-throughput

0.613

High

564294

IF2P
Eukaryotic translation initiation factor 5B

2

6

High-throughput

0.611

High

482971

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.586

High

564284

SSF1
Ribosome biogenesis protein SSF1

3

4

Small-scale

0.585

High

382930

RL25
Large ribosomal subunit protein uL23

2

4

High-throughput

0.584

High

405406

RL26A
Large ribosomal subunit protein uL24A

2

7

High-throughput

0.584

High

406755

RS3
Small ribosomal subunit protein uS3

2

2

Small-scale

0.584

High

471998

RL31A
Large ribosomal subunit protein eL31A

2

5

High-throughput

0.584

High

564229

SIS1
Protein SIS1

2

2

High-throughput

0.584

High

564232

KRR1
KRR1 small subunit processome component

2

4

Small-scale

0.584

High

564312

RLP7
Ribosome biogenesis protein RLP7

2

8

Small-scale

0.584

High

564314

RL10
Large ribosomal subunit protein uL16

2

2

Small-scale

0.584

High

564328

DXO
Decapping nuclease RAI1

2

1

Small-scale

0.584

High

564346

NOP15
Ribosome biogenesis protein 15

2

5

Small-scale

0.584

High

564379

NOC4
Nucleolar complex protein 4

2

7

Small-scale

0.584

High

564287

RIX1
Pre-rRNA-processing protein RIX1

2

0

Small-scale

0.559

High

564301

ARB1
ABC transporter ATP-binding protein ARB1

2

1

Small-scale

0.558

High

564382

RLP24
Ribosome biogenesis protein RLP24

2

6

Small-scale

0.558

High

564224

PWP1
Periodic tryptophan protein 1

1

14

High-throughput

0.553

High

564274

ENP1
Essential nuclear protein 1

1

3

High-throughput

0.553

High

564315

ELP2
Elongator complex protein 2

1

10

High-throughput

0.553

High

564339

COPA
Coatomer subunit alpha

1

5

High-throughput

0.553

High

564393

YTM1
Ribosome biogenesis protein YTM1

1

11

Small-scale

0.553

High

564398

NOP56
Nucleolar protein 56

1

9

Small-scale

0.553

High

490249

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.552

High

564304

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

419795

SNF1
Carbon catabolite-derepressing protein kinase

2

3

Small-scale

0.543

High

510168

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.536

High

564223

DBP4
ATP-dependent RNA helicase HCA4

1

14

High-throughput

0.536

High

564278

DBP8
ATP-dependent RNA helicase DBP8

1

4

High-throughput

0.536

High

564283

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.536

High

564352

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

High-throughput

0.536

High

564396

CFT2
Cleavage factor two protein 2

1

1

High-throughput

0.536

High

564263

EBP2
rRNA-processing protein EBP2

2

3

Small-scale

0.535

High

524147

CAF20
Cap-associated protein CAF20

2

2

High-throughput

0.533

High

564256

MRT4
Ribosome assembly factor MRT4

2

5

Small-scale

0.533

High

564329

NSA1
Ribosome biogenesis protein NSA1

2

2

Small-scale

0.533

High

564375

RQC1
Ribosome quality control complex subunit 1

2

1

Small-scale

0.533

High

564237

SBA1
Co-chaperone protein SBA1

1

1

Small-scale

0.527

High

564238

TF2B
Transcription initiation factor IIB

2

5

High-throughput

0.521

High

564395

NOP53
Ribosome biogenesis protein NOP53

2

2

Small-scale

0.521

High

564240

PAP
Poly(A) polymerase

1

0

High-throughput

0.513

High

564380

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.513

High

412644

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

477111

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

564338

SSK2
MAP kinase kinase kinase SSK2

1

2

High-throughput

0.501

High

564241

XPO1
Exportin-1

1

4

High-throughput

0.489

High

564303

IMB4
Importin subunit beta-4

1

3

Small-scale

0.489

High

564354

PVH1
Tyrosine-protein phosphatase YVH1

1

1

Small-scale

0.489

High

564383

BUD20
Bud site selection protein 20

1

1

High-throughput

0.489

High

357452

RLA4
Large ribosomal subunit protein P2B

1

4

High-throughput

0.479

High

357630

RL28
Large ribosomal subunit protein uL15

1

2

High-throughput

0.479

High

357861

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.479

High

382705

RL24A
Large ribosomal subunit protein eL24A

1

6

High-throughput

0.479

High

387874

RL39
Large ribosomal subunit protein eL39

1

1

High-throughput

0.479

High

399319

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.479

High

399723

RLA1
Large ribosomal subunit protein P1A

1

4

High-throughput

0.479

High

399842

RLA2
Large ribosomal subunit protein P2A

1

4

High-throughput

0.479

High

404486

RL7A
Large ribosomal subunit protein uL30A

1

8

High-throughput

0.479

High

404798

RL9A
Large ribosomal subunit protein uL6A

1

4

High-throughput

0.479

High

404966

RL6B
Large ribosomal subunit protein eL6B

1

4

High-throughput

0.479

High

405126

RL17A
Large ribosomal subunit protein uL22A

1

3

High-throughput

0.479

High

405949

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

406477

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

413283

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425739

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

450388

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

High-throughput

0.479

High

470841

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

471366

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.479

High

472486

RL31B
Large ribosomal subunit protein eL31B

1

5

High-throughput

0.479

High

478832

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.479

High

479225

RL44B
Large ribosomal subunit protein eL42B

1

2

High-throughput

0.479

High

479576

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.479

High

479900

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

480457

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.479

High

481277

RL2A
Large ribosomal subunit protein uL2A

1

2

High-throughput

0.479

High

481588

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

481859

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

482059

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

482662

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

482821

RL35A
Large ribosomal subunit protein uL29A

1

2

High-throughput

0.479

High

496017

RLA3
Large ribosomal subunit protein P1B

1

4

High-throughput

0.479

High

498779

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.479

High

534875

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

564225

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

Small-scale

0.479

High

564226

RL24B
Large ribosomal subunit protein eL24B

1

6

High-throughput

0.479

High

564231

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

564233

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.479

High

564234

RL16A
Large ribosomal subunit protein uL13A

1

4

High-throughput

0.479

High

564235

RL16B
Large ribosomal subunit protein uL13B

1

4

High-throughput

0.479

High

564236

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

564242

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

564246

ZUO1
Zuotin

1

5

Small-scale

0.479

High

564251

ECM32
Putative ATP-dependent RNA helicase ECM32

1

3

High-throughput

0.479

High

564255

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

564259

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

564260

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

564264

RL14A
Large ribosomal subunit protein eL14A

1

4

High-throughput

0.479

High

564270

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

564271

MAK5
ATP-dependent RNA helicase MAK5

1

14

High-throughput

0.479

High

564272

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

4

High-throughput

0.479

High

564273

GID4
Vacuolar import and degradation protein 24

1

1

High-throughput

0.479

High

564277

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

564280

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.479

High

564289

STM1
Suppressor protein STM1

1

2

High-throughput

0.479

High

564291

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

564293

RBG1
Ribosome-interacting GTPase 1

1

4

High-throughput

0.479

High

564296

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

High-throughput

0.479

High

564298

RS26B
Small ribosomal subunit protein eS26B

1

2

High-throughput

0.479

High

564300

NUG1
Nuclear GTP-binding protein NUG1

1

6

Small-scale

0.479

High

564305

RL13B
Large ribosomal subunit protein eL13B

1

3

High-throughput

0.479

High

564313

NOP2
25S rRNA

1

2

Small-scale

0.479

High

564318

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

564319

RL17B
Large ribosomal subunit protein uL22B

1

3

High-throughput

0.479

High

564324

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

564325

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

564326

RL4B
Large ribosomal subunit protein uL4B

1

6

High-throughput

0.479

High

564327

RL9B
Large ribosomal subunit protein uL6B

1

4

High-throughput

0.479

High

564331

RL26B
Large ribosomal subunit protein uL24B

1

7

High-throughput

0.479

High

564340

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

Small-scale

0.479

High

564344

JJJ1
J protein JJJ1

1

7

High-throughput

0.479

High

564347

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

564349

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

564353

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

564355

RL6A
Large ribosomal subunit protein eL6A

1

4

High-throughput

0.479

High

564357

RL21A
Large ribosomal subunit protein eL21A

1

2

High-throughput

0.479

High

564361

HAS1
ATP-dependent RNA helicase HAS1

1

15

High-throughput

0.479

High

564362

CLU
Clustered mitochondria protein 1

1

2

High-throughput

0.479

High

564367

HMO1
High mobility group protein 1

1

5

High-throughput

0.479

High

564369

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

564372

LTN1
E3 ubiquitin-protein ligase listerin

1

1

Small-scale

0.479

High

564378

RRP15
Ribosomal RNA-processing protein 15

1

1

Small-scale

0.479

High

564381

ELP1
Elongator complex protein 1

1

1

High-throughput

0.479

High

564391

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

564397

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

564363

USA1
U1 SNP1-associating protein 1

1

1

High-throughput

0.464

High

479311

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.458

High

564243

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.458

High

564265

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

564288

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

564302

THO1
Protein THO1

1

0

High-throughput

0.458

High

564341

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

515162

SCH9
Serine/threonine-protein kinase SCH9

1

2

High-throughput

0.457

High

564299

RSP5
E3 ubiquitin-protein ligase RSP5

1

12

High-throughput

0.457

High

564386

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.457

High

493125

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

564249

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

564285

RPF1
Ribosome production factor 1

1

3

High-throughput

0.445

High

564360

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.445

High

564373

RRP5
rRNA biogenesis protein RRP5

1

2

Small-scale

0.445

High

564345

RHO5
GTP-binding protein RHO5

1

1

Small-scale

0.439

High

532762

ACOX
Acyl-coenzyme A oxidase

1

2

High-throughput

0.437

High

557854

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.437

High

564228

DBP2
ATP-dependent RNA helicase DBP2

1

4

High-throughput

0.437

High

564250

PP12
Serine/threonine-protein phosphatase PP1-2

1

3

Small-scale

0.437

High

564252

CHD1
Chromo domain-containing protein 1

1

5

High-throughput

0.437

High

564257

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.437

High

564258

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.437

High

564262

EAP1
Protein EAP1

1

2

High-throughput

0.437

High

564267

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.437

High

564276

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.437

High

564279

ECM29
Proteasome component ECM29

1

4

High-throughput

0.437

High

564281

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.437

High

564292

ECM1
Shuttling pre-60S factor ECM1

1

1

High-throughput

0.437

High

564297

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

4

High-throughput

0.437

High

564307

TM108
Protein TMA108

1

1

High-throughput

0.437

High

564309

ULP2
Ubiquitin-like-specific protease 2

1

1

Small-scale

0.437

High

564310

SNL1
HSP70 co-chaperone SNL1

1

1

Small-scale

0.437

High

564311

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.437

High

564316

UTP10
U3 small nucleolar RNA-associated protein 10

1

3

High-throughput

0.437

High

564317

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

1

Small-scale

0.437

High

564320

ALB1
Ribosome biogenesis protein ALB1

1

1

High-throughput

0.437

High

564322

URB2
Nucleolar pre-ribosomal-associated protein 2

1

1

High-throughput

0.437

High

564332

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.437

High

564333

SLX9
Ribosome biogenesis protein SLX9

1

1

High-throughput

0.437

High

564334

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.437

High

564336

SDA1
Protein SDA1

1

1

High-throughput

0.437

High

564337

H1
Histone H1

1

1

High-throughput

0.437

High

564343

GIS2
Zinc finger protein GIS2

1

7

High-throughput

0.437

High

564348

SAM50
Sorting assembly machinery 50 kDa subunit

1

3

High-throughput

0.437

High

564351

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

564356

ABF2
ARS-binding factor 2, mitochondrial

1

4

High-throughput

0.437

High

564359

TOM1
E3 ubiquitin-protein ligase TOM1

1

12

High-throughput

0.437

High

564370

PUF6
Pumilio homology domain family member 6

1

2

Small-scale

0.437

High

564371

UTP14
U3 small nucleolar RNA-associated protein 14

1

4

High-throughput

0.437

High

564385

SGO1
Shugoshin

1

3

High-throughput

0.437

High

564389

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

564390

BMS1
Ribosome biogenesis protein BMS1

1

3

High-throughput

0.437

High

564400

RQC2
Ribosome quality control complex subunit 2

1

1

High-throughput

0.437

High

564401

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.437

High

564402

EFG1P
rRNA-processing protein EFG1

1

2

Small-scale

0.437

High

564261

NDK
Nucleoside diphosphate kinase

1

0

High-throughput

0.426

High

564366

CAB5
Dephospho-CoA kinase CAB5

1

0

High-throughput

0.426

High

564244

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

High-throughput

0.407

High

564374

ERP1
Protein ERP1

1

1

High-throughput

0.407

High

564388

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.407

High

564394

THP3
Protein THP3

1

1

Small-scale

0.407

High

564275

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

2

0

Small-scale

0.305

High

564248

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.279

Low

564306

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.261

Low

145859

MBF1
Multiprotein-bridging factor 1

1

0

High-throughput

0.249

Low

564245

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

564247

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

564254

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

564321

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

564358

SHR3
Secretory component protein SHR3

1

0

High-throughput

0.249

Low

564365

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

564368

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.249

Low

564376

YL278
Uncharacterized transcriptional regulatory protein YLR278C

1

0

High-throughput

0.249

Low

564392

MDN1
Midasin

1

0

High-throughput

0.249

Low

564227

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.232

Low

564230

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

564253

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.232

Low

564268

CCL1
Cyclin CCL1

1

0

High-throughput

0.232

Low

564290

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

564377

YP114
Uncharacterized TLC domain-containing protein YPR114W

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024