Protein: DBP4
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)

Gene: DBP4, HCA4
Organism: Saccharomyces cerevisiae S288C
Interactions: 198
UniProt ID: P20448

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

593690

HAS1
ATP-dependent RNA helicase HAS1

4

18

High-throughput

0.904

High

593593

PWP2
Periodic tryptophan protein 2

3

19

High-throughput

0.855

High

593578

DBP4
ATP-dependent RNA helicase HCA4

2

17

High-throughput

0.830

High

593696

DHR1
Probable ATP-dependent RNA helicase DHR1

2

12

High-throughput

0.754

High

593703

UTP21
U3 small nucleolar RNA-associated protein 21

2

17

Small-scale

0.754

High

593707

ESF1
Pre-rRNA-processing protein ESF1

4

3

High-throughput

0.705

High

593675

SQS1
Protein SQS1

1

2

High-throughput

0.698

High

593704

SGD1
Suppressor of glycerol defect protein 1

1

5

High-throughput

0.698

High

549326

FBRL
rRNA 2'-O-methyltransferase fibrillarin

4

9

High-throughput

0.696

High

593730

NOP56
Nucleolar protein 56

4

15

High-throughput

0.694

High

593710

BFR2
Protein BFR2

3

2

Small-scale

0.680

High

593674

ESF2
Pre-rRNA-processing protein ESF2

3

7

Small-scale

0.672

High

593732

NOP58
Nucleolar protein 58

3

15

High-throughput

0.662

High

593731

RRP36
rRNA biogenesis protein RRP36

3

2

Small-scale

0.658

High

593629

ENP1
Essential nuclear protein 1

3

9

High-throughput

0.640

High

593658

UTP10
U3 small nucleolar RNA-associated protein 10

3

6

High-throughput

0.640

High

593673

UTP22
U3 small nucleolar RNA-associated protein 22

2

2

High-throughput

0.637

High

593723

SAS10
Something about silencing protein 10

2

2

High-throughput

0.637

High

376628

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

8

High-throughput

0.621

High

593584

RNA14
mRNA 3'-end-processing protein RNA14

2

10

High-throughput

0.621

High

593591

SRO9
RNA-binding protein SRO9

2

6

High-throughput

0.621

High

593611

PP12
Serine/threonine-protein phosphatase PP1-2

2

5

High-throughput

0.621

High

593614

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

4

High-throughput

0.621

High

593657

PFS2
Polyadenylation factor subunit 2

2

18

High-throughput

0.621

High

593662

FIP1
Pre-mRNA polyadenylation factor FIP1

2

1

High-throughput

0.621

High

593682

PTA1
Pre-tRNA-processing protein PTA1

2

1

High-throughput

0.621

High

593705

YSH1
Endoribonuclease YSH1

2

3

High-throughput

0.621

High

593714

NOP12
Nucleolar protein 12

2

19

High-throughput

0.621

High

593722

CFT2
Cleavage factor two protein 2

2

1

High-throughput

0.621

High

593665

NOL10
Ribosome biogenesis protein ENP2

2

2

Small-scale

0.618

High

593624

RL1D1
Ribosome biogenesis protein UTP30

1

6

High-throughput

0.618

High

593632

DBP8
ATP-dependent RNA helicase DBP8

1

18

High-throughput

0.618

High

593661

ROK1
ATP-dependent RNA helicase ROK1

1

13

High-throughput

0.618

High

593699

UTP14
U3 small nucleolar RNA-associated protein 14

2

4

High-throughput

0.614

High

593596

RS7A
Small ribosomal subunit protein eS7A

2

9

High-throughput

0.611

High

593700

RRP5
rRNA biogenesis protein RRP5

2

10

High-throughput

0.611

High

593677

NAT10
RNA cytidine acetyltransferase

2

6

High-throughput

0.601

High

593602

PAP
Poly(A) polymerase

2

0

High-throughput

0.595

High

593644

PTI1
Protein PTI1

2

0

High-throughput

0.595

High

593656

REF2
RNA end formation protein 2

2

0

High-throughput

0.595

High

593650

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

593608

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

2

16

High-throughput

0.588

High

593625

RPF2
Ribosome biogenesis protein RPF2

2

3

High-throughput

0.588

High

593592

KRR1
KRR1 small subunit processome component

2

11

High-throughput

0.584

High

593634

UTP9
U3 small nucleolar RNA-associated protein 9

2

1

High-throughput

0.584

High

593709

NOC4
Nucleolar complex protein 4

2

18

High-throughput

0.584

High

549949

CSK21
Casein kinase II subunit alpha

1

13

High-throughput

0.582

High

490310

HSP71
Heat shock protein SSA1

2

16

High-throughput

0.571

High

593583

SIS1
Protein SIS1

2

10

High-throughput

0.571

High

510231

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.552

High

593660

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.541

High

404968

RL6B
Large ribosomal subunit protein eL6B

1

8

High-throughput

0.536

High

498789

RL4A
Large ribosomal subunit protein uL4A

1

11

High-throughput

0.536

High

564223

RL8A
Large ribosomal subunit protein eL8A

1

14

High-throughput

0.536

High

593595

RL16B
Large ribosomal subunit protein uL13B

1

16

High-throughput

0.536

High

593603

XPO1
Exportin-1

1

18

High-throughput

0.536

High

593623

SWD2
COMPASS component SWD2

1

17

High-throughput

0.536

High

593648

RL13B
Large ribosomal subunit protein eL13B

1

12

High-throughput

0.536

High

593733

RL13A
Large ribosomal subunit protein eL13A

1

12

High-throughput

0.536

High

524159

CAF20
Cap-associated protein CAF20

2

3

High-throughput

0.533

High

593598

SBA1
Co-chaperone protein SBA1

1

3

Small-scale

0.527

High

341767

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.515

High

392287

H2A2
Histone H2A.2

1

11

High-throughput

0.515

High

593581

BUR1
Serine/threonine-protein kinase BUR1

1

8

High-throughput

0.515

High

593582

DPB2
DNA polymerase epsilon subunit B

1

1

High-throughput

0.515

High

593636

STM1
Suppressor protein STM1

1

2

High-throughput

0.515

High

593694

HMO1
High mobility group protein 1

1

13

High-throughput

0.515

High

593718

RRS1
Regulator of ribosome biosynthesis

1

3

High-throughput

0.515

High

593724

YRA1
RNA annealing protein YRA1

1

11

High-throughput

0.515

High

593725

MAK21
Ribosome biogenesis protein MAK21

1

18

High-throughput

0.515

High

412653

KAPA
cAMP-dependent protein kinase type 1

1

11

High-throughput

0.501

High

419800

SNF1
Carbon catabolite-derepressing protein kinase

1

2

High-throughput

0.501

High

593580

KC11
Casein kinase I homolog 1

1

10

High-throughput

0.501

High

593586

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

6

High-throughput

0.501

High

593670

ATG1
Serine/threonine-protein kinase ATG1

1

5

High-throughput

0.501

High

593691

SKY1
Serine/threonine-protein kinase SKY1

1

20

High-throughput

0.501

High

593721

RTK1
Probable serine/threonine-protein kinase RTK1

1

7

High-throughput

0.501

High

593579

TRX1
Thioredoxin-1

1

0

High-throughput

0.493

High

367730

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.489

High

399327

RLA0
Large ribosomal subunit protein uL10

1

11

High-throughput

0.489

High

593630

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

3

High-throughput

0.489

High

593669

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.489

High

593728

SMT3
Ubiquitin-like protein SMT3

1

3

High-throughput

0.481

High

141149

RS9A
Small ribosomal subunit protein uS4A

1

12

High-throughput

0.479

High

382945

RL25
Large ribosomal subunit protein uL23

1

11

High-throughput

0.479

High

405426

RL26A
Large ribosomal subunit protein uL24A

1

13

High-throughput

0.479

High

406776

RS3
Small ribosomal subunit protein uS3

1

9

High-throughput

0.479

High

407721

RS13
Small ribosomal subunit protein uS15

1

7

High-throughput

0.479

High

413300

RS14A
Small ribosomal subunit protein uS11A

1

12

High-throughput

0.479

High

425760

RS19A
Small ribosomal subunit protein eS19A

1

15

High-throughput

0.479

High

479679

RS4A
Small ribosomal subunit protein eS4A

1

4

High-throughput

0.479

High

479917

RS6A
Small ribosomal subunit protein eS6A

1

11

High-throughput

0.479

High

481279

RL2A
Large ribosomal subunit protein uL2A

1

9

High-throughput

0.479

High

593587

RRP43
Exosome complex component RRP43

1

2

High-throughput

0.479

High

593588

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.479

High

593589

RS2
Small ribosomal subunit protein uS5

1

11

High-throughput

0.479

High

593597

SPT5
Transcription elongation factor SPT5

1

4

High-throughput

0.479

High

593599

TF2B
Transcription initiation factor IIB

1

9

High-throughput

0.479

High

593600

BMH1
Protein BMH1

1

9

High-throughput

0.479

High

593606

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

5

High-throughput

0.479

High

593612

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

9

High-throughput

0.479

High

593617

DCA13
Protein SOF1

1

17

High-throughput

0.479

High

593618

UTP11
U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.479

High

593619

RS27A
Small ribosomal subunit protein eS27A

1

7

High-throughput

0.479

High

593621

DOA1
Protein DOA1

1

19

Small-scale

0.479

High

593622

EAP1
Protein EAP1

1

3

High-throughput

0.479

High

593626

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.479

High

593627

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.479

High

593635

RRP8
25S rRNA

1

2

High-throughput

0.479

High

593645

UTP7
U3 small nucleolar RNA-associated protein 7

1

16

High-throughput

0.479

High

593646

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

2

High-throughput

0.479

High

593651

UTP25
U3 small nucleolar RNA-associated protein 25

1

1

High-throughput

0.479

High

593654

DSN1
Kinetochore-associated protein DSN1

1

5

High-throughput

0.479

High

593664

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

3

Small-scale

0.479

High

593676

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

19

High-throughput

0.479

High

593678

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.479

High

593679

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

8

High-throughput

0.479

High

593680

ORC1
Origin recognition complex subunit 1

1

5

High-throughput

0.479

High

593683

RS15
Small ribosomal subunit protein uS19

1

8

High-throughput

0.479

High

593686

XRN2
5'-3' exoribonuclease 2

1

6

High-throughput

0.479

High

593687

UTP17
NET1-associated nuclear protein 1

1

16

High-throughput

0.479

High

593688

ESP1
Separin

1

2

High-throughput

0.479

High

593689

TOM1
E3 ubiquitin-protein ligase TOM1

1

15

High-throughput

0.479

High

593695

UTP5
U3 small nucleolar RNA-associated protein 5

1

14

High-throughput

0.479

High

593697

UTP15
U3 small nucleolar RNA-associated protein 15

1

16

High-throughput

0.479

High

593698

BUD22
Bud site selection protein 22

1

1

High-throughput

0.479

High

593701

FCF1
rRNA-processing protein FCF1

1

5

High-throughput

0.479

High

593702

UTP13
U3 small nucleolar RNA-associated protein 13

1

20

High-throughput

0.479

High

593712

CMS1
Protein CMS1

1

1

High-throughput

0.479

High

593713

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

1

High-throughput

0.479

High

593715

SGO1
Shugoshin

1

6

High-throughput

0.479

High

593716

ESA1
Histone acetyltransferase ESA1

1

4

Small-scale

0.479

High

593717

RS10A
Small ribosomal subunit protein eS10A

1

11

High-throughput

0.479

High

593719

BMS1
Ribosome biogenesis protein BMS1

1

7

High-throughput

0.479

High

593727

UTP12
U3 small nucleolar RNA-associated protein 12

1

16

High-throughput

0.479

High

593734

EFG1P
rRNA-processing protein EFG1

1

2

High-throughput

0.479

High

593735

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

593605

EF2
Elongation factor 2

1

7

High-throughput

0.470

High

593643

RV167
Reduced viability upon starvation protein 167

1

8

High-throughput

0.470

High

593671

MLC1
Myosin light chain 1

1

3

High-throughput

0.470

High

593708

CORO
Coronin-like protein

1

11

High-throughput

0.470

High

593652

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

593685

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

593706

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

593720

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

365773

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

404491

RL7A
Large ribosomal subunit protein uL30A

1

15

High-throughput

0.445

High

477889

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.445

High

493176

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

534880

RL3
Large ribosomal subunit protein uL3

1

9

High-throughput

0.445

High

543175

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.445

High

560556

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.445

High

587922

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.445

High

593590

MAS5
Mitochondrial protein import protein MAS5

1

11

High-throughput

0.445

High

593594

RL16A
Large ribosomal subunit protein uL13A

1

16

High-throughput

0.445

High

593601

RL8B
Large ribosomal subunit protein eL8B

1

14

High-throughput

0.445

High

593604

HS104
Heat shock protein 104

1

6

High-throughput

0.445

High

593607

ZUO1
Zuotin

1

8

High-throughput

0.445

High

593609

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

593610

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.445

High

593615

HSP78
Heat shock protein 78, mitochondrial

1

8

High-throughput

0.445

High

593620

LHS1
Heat shock protein 70 homolog LHS1

1

17

High-throughput

0.445

High

593628

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

4

High-throughput

0.445

High

593633

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

593637

TCPB
T-complex protein 1 subunit beta

1

6

High-throughput

0.445

High

593638

TCPG
T-complex protein 1 subunit gamma

1

3

High-throughput

0.445

High

593639

TCPD
T-complex protein 1 subunit delta

1

6

High-throughput

0.445

High

593641

CAJ1
Protein CAJ1

1

9

High-throughput

0.445

High

593647

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

593663

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.445

High

593668

RL4B
Large ribosomal subunit protein uL4B

1

11

High-throughput

0.445

High

593681

SEN1
Helicase SEN1

1

8

Small-scale

0.445

High

593684

RL6A
Large ribosomal subunit protein eL6A

1

8

High-throughput

0.445

High

593726

RL7B
Large ribosomal subunit protein uL30B

1

15

High-throughput

0.445

High

357880

RS17A
Small ribosomal subunit protein eS17A

1

8

High-throughput

0.437

High

470859

RS22A
Small ribosomal subunit protein uS8A

1

9

High-throughput

0.437

High

472015

RL31A
Large ribosomal subunit protein eL31A

1

16

High-throughput

0.437

High

480477

RS8A
Small ribosomal subunit protein eS8A

1

11

High-throughput

0.437

High

482078

RS18A
Small ribosomal subunit protein uS13A

1

7

High-throughput

0.437

High

593613

RSSA1
Small ribosomal subunit protein uS2A

1

14

High-throughput

0.437

High

593616

RS3A1
Small ribosomal subunit protein eS1A

1

10

High-throughput

0.437

High

593631

RS20
Small ribosomal subunit protein uS10

1

7

High-throughput

0.437

High

593642

LAA1
AP-1 accessory protein LAA1

1

8

High-throughput

0.437

High

593667

RS12
Small ribosomal subunit protein eS12

1

7

High-throughput

0.437

High

593672

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.437

High

593692

BUL2
Ubiquitin ligase-binding protein BUL2

1

1

Small-scale

0.437

High

593711

VAM6
Vacuolar morphogenesis protein 6

1

6

High-throughput

0.437

High

593640

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.426

High

593585

SCJ1
DnaJ-related protein SCJ1

1

4

High-throughput

0.407

High

593649

JEM1
DnaJ-like chaperone JEM1

1

6

High-throughput

0.407

High

593653

DJP1
DnaJ-like protein 1

1

9

High-throughput

0.407

High

593655

RL10
Large ribosomal subunit protein uL16

1

12

High-throughput

0.407

High

593659

ERJ5
ER-localized J domain-containing protein 5

1

8

High-throughput

0.407

High

593666

HLJ1
Protein HLJ1

1

4

High-throughput

0.407

High

593729

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

576181

FUN14
Protein FUN14

1

0

High-throughput

0.269

Low

593693

ENT5
Epsin-5

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024