Protein: PAT1
Deadenylation-dependent mRNA-decapping factor PAT1 (DNA topoisomerase 2-associated protein PAT1) (Decapping activator and translational repressor PAT1) (Topoisomerase II-associated protein PAT1) (mRNA turnover protein 1)

Gene: PAT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 213
UniProt ID: P25644

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000776 - kinetochore
GO:0000932 - P-body
GO:0001731 - formation of translation preinitiation complex
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635880

LSM1
Sm-like protein LSm1

18

10

Small-scale

0.987

High

635852

LSM2
U6 snRNA-associated Sm-like protein LSm2

11

5

Small-scale

0.979

High

635869

LSM5
U6 snRNA-associated Sm-like protein LSm5

11

1

Small-scale

0.977

High

635868

LSM4
U6 snRNA-associated Sm-like protein LSm4

10

2

Small-scale

0.976

High

635902

LSM7
U6 snRNA-associated Sm-like protein LSm7

10

7

Small-scale

0.975

High

635906

LSM3
U6 snRNA-associated Sm-like protein LSm3

10

10

Small-scale

0.972

High

635927

LSM6
U6 snRNA-associated Sm-like protein LSm6

9

1

Small-scale

0.970

High

635881

LSM8
U6 snRNA-associated Sm-like protein LSm8

3

10

High-throughput

0.835

High

635811

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

2

5

Small-scale

0.768

High

635862

DHH1
ATP-dependent RNA helicase DHH1

16

7

Small-scale

0.763

High

604930

XRN1
5'-3' exoribonuclease 1

11

4

Small-scale

0.756

High

635893

DCP2
m7GpppN-mRNA hydrolase

8

3

Small-scale

0.749

High

543292

HSC82
ATP-dependent molecular chaperone HSC82

4

5

High-throughput

0.678

High

635816

XPO1
Exportin-1

3

6

Small-scale

0.654

High

635953

DCP1
mRNA-decapping enzyme subunit 1

4

0

Small-scale

0.651

High

635877

SCD6
Protein SCD6

3

2

Small-scale

0.645

High

635946

SCM3
Protein SCM3

3

0

Small-scale

0.630

High

493324

HSP72
Heat shock protein SSA2

3

6

Small-scale

0.624

High

365882

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.622

High

635828

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

0

Small-scale

0.614

High

376657

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

1

Small-scale

0.611

High

635814

RENT1
ATP-dependent helicase NAM7

2

2

Small-scale

0.586

High

357914

RS17A
Small ribosomal subunit protein eS17A

2

1

Small-scale

0.584

High

382980

RL25
Large ribosomal subunit protein uL23

2

1

Small-scale

0.584

High

410316

SC160
Protein SCP160

2

5

Small-scale

0.584

High

479956

RS6A
Small ribosomal subunit protein eS6A

2

2

Small-scale

0.584

High

635866

EDC3
Enhancer of mRNA-decapping protein 3

2

1

Small-scale

0.584

High

635870

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

Small-scale

0.571

High

635903

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

Small-scale

0.571

High

635944

RIO1
Serine/threonine-protein kinase RIO1

2

0

Small-scale

0.561

High

635912

RS15
Small ribosomal subunit protein uS19

2

0

Small-scale

0.559

High

477951

HSP77
Import motor subunit, mitochondrial

2

4

High-throughput

0.552

High

510431

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

409823

NOT2
General negative regulator of transcription subunit 2

1

5

High-throughput

0.541

High

635829

NOT4
General negative regulator of transcription subunit 4

1

1

High-throughput

0.541

High

635832

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.541

High

635949

AIR2
Protein AIR2

1

2

High-throughput

0.541

High

635896

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

635910

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

593040

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.529

High

635890

GPG1
Heterotrimeric G protein gamma subunit GPG1

1

0

High-throughput

0.513

High

635886

SF3B1
U2 snRNP component HSH155

1

2

High-throughput

0.508

High

635905

ZDS2
Protein ZDS2

1

2

High-throughput

0.508

High

409608

KAPC
cAMP-dependent protein kinase type 3

1

3

Small-scale

0.501

High

412672

KAPA
cAMP-dependent protein kinase type 1

1

3

Small-scale

0.501

High

412952

KAPB
cAMP-dependent protein kinase type 2

1

3

Small-scale

0.501

High

485466

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.500

High

554574

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

420089

TOP2
DNA topoisomerase 2

1

0

Small-scale

0.486

High

635895

BUD17
Putative pyridoxal kinase BUD17

1

0

High-throughput

0.486

High

635897

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.486

High

635917

MIX17
Mitochondrial intermembrane space cysteine motif-containing protein MIX17

1

0

High-throughput

0.486

High

635919

DOP1
Protein dopey

1

0

High-throughput

0.486

High

409954

NOT3
General negative regulator of transcription subunit 3

1

3

Small-scale

0.481

High

471478

RS28B
Small ribosomal subunit protein eS28B

1

1

Small-scale

0.481

High

635889

KIP3
Kinesin-like protein KIP3

1

2

High-throughput

0.481

High

635952

NOT5
General negative regulator of transcription subunit 5

1

3

Small-scale

0.481

High

635955

RS28A
Small ribosomal subunit protein eS28A

1

1

Small-scale

0.481

High

141188

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

404512

RL7A
Large ribosomal subunit protein uL30A

1

2

Small-scale

0.479

High

404979

RL6B
Large ribosomal subunit protein eL6B

1

2

Small-scale

0.479

High

405465

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

406829

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

407479

RS9B
Small ribosomal subunit protein uS4B

1

2

Small-scale

0.479

High

407762

RS13
Small ribosomal subunit protein uS15

1

1

Small-scale

0.479

High

408288

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

413338

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

425801

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

449934

HSP73
Heat shock protein SSA3

1

6

Small-scale

0.479

High

482114

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

490485

HSP71
Heat shock protein SSA1

1

6

Small-scale

0.479

High

498814

RL4A
Large ribosomal subunit protein uL4A

1

3

Small-scale

0.479

High

548361

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

2

High-throughput

0.479

High

605306

HSP74
Heat shock protein SSA4

1

6

Small-scale

0.479

High

613642

RS3A2
Small ribosomal subunit protein eS1B

1

2

Small-scale

0.479

High

621984

SSD1
Protein SSD1

1

2

Small-scale

0.479

High

631706

RS2
Small ribosomal subunit protein uS5

1

1

Small-scale

0.479

High

635812

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

635813

HRR25
Casein kinase I homolog HRR25

1

1

Small-scale

0.479

High

635827

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

635830

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.479

High

635831

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

635834

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

635835

CENPA
Histone H3-like centromeric protein CSE4

1

1

Small-scale

0.479

High

635839

RM07
Large ribosomal subunit protein uL5m

1

1

High-throughput

0.479

High

635856

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

635857

RL14B
Large ribosomal subunit protein eL14B

1

1

Small-scale

0.479

High

635874

RL10
Large ribosomal subunit protein uL16

1

1

Small-scale

0.479

High

635884

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

635899

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.479

High

635909

NAM8
Protein NAM8

1

3

High-throughput

0.479

High

635914

RL6A
Large ribosomal subunit protein eL6A

1

2

Small-scale

0.479

High

635915

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

635924

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.479

High

635930

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

4

Small-scale

0.479

High

635937

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

635941

YRA1
RNA annealing protein YRA1

1

1

Small-scale

0.479

High

635942

PSH1
RING finger protein PSH1

1

2

Small-scale

0.479

High

635943

BBP
Branchpoint-bridging protein

1

1

Small-scale

0.479

High

565217

SAC7
GTPase-activating protein SAC7

1

1

High-throughput

0.464

High

539702

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.460

High

561111

CDC23
Anaphase-promoting complex subunit CDC23

1

0

High-throughput

0.460

High

565260

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.460

High

635867

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

635908

DAD4
DASH complex subunit DAD4

1

0

High-throughput

0.460

High

635922

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.460

High

479694

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

480516

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

481475

RS11B
Small ribosomal subunit protein uS17B

1

0

Small-scale

0.458

High

481743

RS16B
Small ribosomal subunit protein uS9B

1

0

Small-scale

0.458

High

482672

RL19B
Large ribosomal subunit protein eL19

1

0

Small-scale

0.458

High

482833

RL35A
Large ribosomal subunit protein uL29A

1

0

Small-scale

0.458

High

634508

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

635820

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

635822

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

635823

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

635825

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

635836

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

635854

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

635859

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.458

High

635871

TM108
Protein TMA108

1

0

High-throughput

0.458

High

635872

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

635883

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

635891

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.458

High

635892

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

635907

ACT
Actin

1

0

Small-scale

0.458

High

635918

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

635920

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

635921

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

635923

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

635929

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

635931

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

635934

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

635935

SGO1
Shugoshin

1

0

High-throughput

0.458

High

635936

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

635938

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

635939

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

635940

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

635950

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.458

High

635954

RS25A
Small ribosomal subunit protein eS25A

1

0

Small-scale

0.458

High

635853

SIF2
SIR4-interacting protein SIF2

1

1

High-throughput

0.457

High

635925

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

1

High-throughput

0.457

High

635948

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.457

High

367789

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

635821

PRP19
Pre-mRNA-processing factor 19

1

2

Small-scale

0.445

High

635826

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

635861

CAJ1
Protein CAJ1

1

4

High-throughput

0.445

High

635864

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

3

High-throughput

0.445

High

635865

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

5

High-throughput

0.445

High

635885

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.445

High

635887

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.445

High

635945

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

635858

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

635860

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

635878

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.438

High

635928

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

635951

PSF1
DNA replication complex GINS protein PSF1

1

0

High-throughput

0.438

High

405959

RL33A
Large ribosomal subunit protein eL33A

1

1

Small-scale

0.437

High

635817

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.437

High

635863

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

635879

RL17B
Large ribosomal subunit protein uL22B

1

1

Small-scale

0.437

High

635901

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.437

High

635875

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

635898

FOL1
Folic acid synthesis protein FOL1 [Includes: Dihydroneopterin aldolase

1

0

High-throughput

0.426

High

635837

RM03
Large ribosomal subunit protein mL44

2

0

Small-scale

0.305

High

635933

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.279

Low

635815

RF1M
Peptide chain release factor 1, mitochondrial

1

0

High-throughput

0.265

Low

635911

SPR6
Sporulation-specific protein

1

0

High-throughput

0.265

Low

343546

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

378301

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

587960

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

471743

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.249

Low

478847

RL20B
Large ribosomal subunit protein eL20B

1

0

Small-scale

0.249

Low

520476

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.249

Low

534455

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.249

Low

589350

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

607386

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low

607455

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.249

Low

615579

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.249

Low

629828

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.249

Low

635334

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

635749

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

635818

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

635819

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

635824

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

635833

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.249

Low

635838

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.249

Low

635840

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

635841

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

635842

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

635843

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

635844

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

635845

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

635846

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

635847

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.249

Low

635848

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

635849

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

635850

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.249

Low

635851

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

635873

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.249

Low

635876

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

635888

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

635894

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

635900

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

635904

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.249

Low

635913

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

635916

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

635926

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

635932

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low

635947

UTP23
rRNA-processing protein UTP23

1

0

High-throughput

0.249

Low

635855

BIT2
Probable target of rapamycin complex 2 subunit BIT2

1

0

High-throughput

0.238

Low

635882

YJZ3
Putative uncharacterized protein YJR023C

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024