Protein: DPYL2
Dihydropyrimidinase-related protein 2 (DRP-2) (Unc-33-like phosphoprotein 2) (ULIP-2)

Gene: DPYL2, Dpysl2
Organism: Mus musculus
Interactions: 146
UniProt ID: O08553

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005929 - cilium
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

147582

DPYL5
Dihydropyrimidinase-related protein 5

1

18

Small-scale

0.713

High

104433

SYGP1
Ras/Rap GTPase-activating protein SynGAP

3

1

High-throughput

0.667

High

147494

DPYL1
Dihydropyrimidinase-related protein 1

1

18

Small-scale

0.621

High

147455

DPYL2
Dihydropyrimidinase-related protein 2

1

18

High-throughput

0.618

High

147578

DLGP1
Disks large-associated protein 1

2

0

High-throughput

0.585

High

147518

SCN9A
Sodium channel protein type 9 subunit alpha

2

3

Small-scale

0.584

High

147524

NEB2
Neurabin-2

2

6

High-throughput

0.584

High

147464

MT3
Metallothionein-3

2

0

Small-scale

0.559

High

147572

MIC19
MICOS complex subunit Mic19

2

0

Small-scale

0.559

High

147491

TNIK
Traf2 and NCK-interacting protein kinase

1

6

High-throughput

0.536

High

147497

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

4

High-throughput

0.536

High

147503

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.536

High

147506

HERC2
E3 ubiquitin-protein ligase HERC2

1

10

High-throughput

0.536

High

147527

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.536

High

147493

VPS45
Vacuolar protein sorting-associated protein 45

2

1

Small-scale

0.533

High

147516

DLG4
Disks large homolog 4

1

0

High-throughput

0.513

High

147526

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

3

High-throughput

0.489

High

147534

MYOME
Myomegalin

1

2

High-throughput

0.489

High

59320

CKAP5
Cytoskeleton-associated protein 5

1

1

Small-scale

0.479

High

108333

G3X9H5
Huntingtin

1

6

High-throughput

0.479

High

147458

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

Small-scale

0.479

High

147460

PRIO
Major prion protein

1

1

Small-scale

0.479

High

147463

CD72
B-cell differentiation antigen CD72

1

1

Small-scale

0.479

High

147472

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

3

Small-scale

0.479

High

147474

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

147477

RUVB1
RuvB-like 1

1

3

High-throughput

0.479

High

147478

RS18
Small ribosomal subunit protein uS13

1

1

Small-scale

0.479

High

147481

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

147482

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

147483

RS17
Small ribosomal subunit protein eS17

1

1

Small-scale

0.479

High

147486

ROCK2
Rho-associated protein kinase 2

1

5

Small-scale

0.479

High

147489

TCPH
T-complex protein 1 subunit eta

1

2

Small-scale

0.479

High

147490

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.479

High

147496

TERA
Transitional endoplasmic reticulum ATPase

1

10

High-throughput

0.479

High

147504

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

8

High-throughput

0.479

High

147507

BRSK1
Serine/threonine-protein kinase BRSK1

1

2

Small-scale

0.479

High

147509

KLRA4
Killer cell lectin-like receptor 4

1

1

Small-scale

0.479

High

147510

CSK21
Casein kinase II subunit alpha

1

9

Small-scale

0.479

High

147513

PRDX2
Peroxiredoxin-2

1

3

Small-scale

0.479

High

147521

LAR4B
La-related protein 4B

1

1

Small-scale

0.479

High

147522

CLCB
Clathrin light chain B

1

1

Small-scale

0.479

High

147533

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

147538

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

3

Small-scale

0.479

High

147543

LIPA2
Liprin-alpha-2

1

1

Small-scale

0.479

High

147544

APH1A
Gamma-secretase subunit APH-1A

1

1

Small-scale

0.479

High

147545

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

12

Small-scale

0.479

High

147546

APH1B
Gamma-secretase subunit APH-1B

1

1

Small-scale

0.479

High

147547

ITCH
E3 ubiquitin-protein ligase Itchy

1

9

Small-scale

0.479

High

147550

SYN3
Synapsin-3

1

2

Small-scale

0.479

High

147551

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

147556

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

2

Small-scale

0.479

High

147557

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

2

Small-scale

0.479

High

147567

CHMP3
Charged multivesicular body protein 3

1

1

Small-scale

0.479

High

147571

ATG12
Ubiquitin-like protein ATG12

1

1

Small-scale

0.479

High

147574

RS19
Small ribosomal subunit protein eS19

1

1

Small-scale

0.479

High

147575

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

2

High-throughput

0.479

High

147579

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

Small-scale

0.479

High

147583

RBCC1
RB1-inducible coiled-coil protein 1

1

3

Small-scale

0.479

High

147587

DREB
Drebrin

1

4

High-throughput

0.479

High

147588

MAP1A
Microtubule-associated protein 1A

1

1

Small-scale

0.479

High

147589

NUMB
Protein numb homolog

1

2

Small-scale

0.479

High

147590

TRIM3
Tripartite motif-containing protein 3

1

5

Small-scale

0.479

High

147591

SEPT6
Septin-6

1

2

Small-scale

0.479

High

147592

RUVB2
RuvB-like 2

1

3

High-throughput

0.479

High

59004

DHX8
ATP-dependent RNA helicase DHX8

1

0

Small-scale

0.458

High

147462

GLNA
Glutamine synthetase

1

0

High-throughput

0.458

High

147468

RL12
Large ribosomal subunit protein uL11

1

0

Small-scale

0.458

High

147469

EPS15
Epidermal growth factor receptor substrate 15

1

0

Small-scale

0.458

High

147470

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

147473

STMN1
Stathmin

1

0

High-throughput

0.458

High

147475

DSC2
Desmocollin-2

1

0

Small-scale

0.458

High

147479

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

Small-scale

0.458

High

147485

STIM1
Stromal interaction molecule 1

1

0

Small-scale

0.458

High

147498

MYO3B
Myosin-IIIb

1

0

Small-scale

0.458

High

147499

MAP9
Microtubule-associated protein 9

1

0

Small-scale

0.458

High

147514

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.458

High

147519

CBPC1
Cytosolic carboxypeptidase 1

1

0

Small-scale

0.458

High

147532

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

Small-scale

0.458

High

147549

PEO1
Twinkle mtDNA helicase

1

0

Small-scale

0.458

High

147553

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.458

High

147555

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.458

High

147559

CAVN3
Caveolae-associated protein 3

1

0

Small-scale

0.458

High

147560

Q91XH5
Sepiapterin reductase

1

0

Small-scale

0.458

High

147561

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.458

High

147562

KAD5
Adenylate kinase isoenzyme 5

1

0

Small-scale

0.458

High

147565

CAD23
Cadherin-23

1

0

Small-scale

0.458

High

147566

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

0

High-throughput

0.458

High

147568

NDUC2
NADH dehydrogenase [ubiquinone] 1 subunit C2

1

0

Small-scale

0.458

High

147569

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

Small-scale

0.458

High

147584

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.458

High

147585

FZD2
Frizzled-2

1

0

Small-scale

0.458

High

147586

ITA2B
Integrin alpha-IIb

1

1

High-throughput

0.457

High

147456

KCNH2
Voltage-gated inwardly rectifying potassium channel KCNH2

1

1

High-throughput

0.445

High

147467

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.445

High

147471

CAV3
Caveolin-3

1

1

High-throughput

0.445

High

147484

1433F
14-3-3 protein eta

1

7

High-throughput

0.445

High

147495

THIOM
Thioredoxin, mitochondrial

1

2

High-throughput

0.445

High

147505

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

High-throughput

0.445

High

147548

FTM
Protein fantom

1

4

High-throughput

0.445

High

73058

B1AWE1
Clathrin light chain

1

1

Small-scale

0.437

High

97725

E9PXB7
E3 ubiquitin-protein ligase

1

9

Small-scale

0.437

High

147457

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

Small-scale

0.437

High

147466

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

2

High-throughput

0.437

High

147476

VP33B
Vacuolar protein sorting-associated protein 33B

1

3

Small-scale

0.437

High

147480

AP2S1
AP-2 complex subunit sigma

1

1

Small-scale

0.437

High

147487

EVL
Ena/VASP-like protein

1

1

Small-scale

0.437

High

147492

SRSF3
Serine/arginine-rich splicing factor 3

1

3

Small-scale

0.437

High

147512

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

2

High-throughput

0.437

High

147517

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

Small-scale

0.437

High

147520

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

1

7

Small-scale

0.437

High

147525

SPOP
Speckle-type POZ protein

1

1

High-throughput

0.437

High

147528

Q7TNI3
Voltage-dependent L-type calcium channel subunit alpha

1

3

Small-scale

0.437

High

147531

SEPT9
Septin-9

1

2

Small-scale

0.437

High

147537

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

7

High-throughput

0.437

High

147540

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.437

High

147552

Q8K1M3
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

1

High-throughput

0.437

High

147563

COA7
Cytochrome c oxidase assembly factor 7

1

1

Small-scale

0.437

High

147570

BT3L4
Transcription factor BTF3 homolog 4

1

1

High-throughput

0.437

High

147576

Q9D031
Ras suppressor protein 1

1

1

Small-scale

0.437

High

147577

VP33A
Vacuolar protein sorting-associated protein 33A

1

3

Small-scale

0.437

High

147593

SEPT3
Neuronal-specific septin-3

1

2

Small-scale

0.437

High

147461

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.426

High

147541

BICD1
Protein bicaudal D homolog 1

1

5

High-throughput

0.407

High

147558

SATB2
DNA-binding protein SATB2

1

1

Small-scale

0.407

High

147581

XPO7
Exportin-7

1

1

High-throughput

0.407

High

147465

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.279

Low

147459

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

147488

LDB1
LIM domain-binding protein 1

1

0

Small-scale

0.249

Low

147500

Q3TYU3
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

Small-scale

0.249

Low

147501

TPPC9
Trafficking protein particle complex subunit 9

1

0

Small-scale

0.249

Low

147502

LIPN
Lipase member N

1

0

Small-scale

0.249

Low

147508

SPG17
Sperm-associated antigen 17

1

0

Small-scale

0.249

Low

147511

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.249

Low

147515

RAI1
Retinoic acid-induced protein 1

1

0

Small-scale

0.249

Low

147523

DCLK2
Serine/threonine-protein kinase DCLK2

1

0

High-throughput

0.249

Low

147529

DPOLN
DNA polymerase nu

1

0

Small-scale

0.249

Low

147530

PKHH1
Pleckstrin homology domain-containing family H member 1

1

0

Small-scale

0.249

Low

147535

ZBT41
Zinc finger and BTB domain-containing protein 41

1

0

Small-scale

0.249

Low

147536

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

Small-scale

0.249

Low

147539

CA216
UPF0500 protein C1orf216 homolog

1

0

Small-scale

0.249

Low

147554

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

0

Small-scale

0.249

Low

147564

NEUA
N-acylneuraminate cytidylyltransferase

1

0

Small-scale

0.249

Low

147573

NSF1C
NSFL1 cofactor p47

1

0

High-throughput

0.249

Low

147580

CB39L
Calcium-binding protein 39-like

1

0

Small-scale

0.249

Low

147542

RD3
Protein RD3

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025