Protein: PSA5
Proteasome subunit alpha type-5 (Macropain subunit PUP2) (Multicatalytic endopeptidase complex subunit PUP2) (Proteasome component PUP2) (Proteinase YSCE subunit PUP2)

Gene: PSA5, PUP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P32379

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0034515 - proteasome storage granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604767

PSB4
Proteasome subunit beta type-4

14

20

Small-scale

0.981

High

597214

PSA7
Probable proteasome subunit alpha type-7

7

20

Small-scale

0.963

High

619428

PSA2
Proteasome subunit alpha type-2

6

19

Small-scale

0.941

High

675397

PSB5
Proteasome subunit beta type-5

5

20

Small-scale

0.912

High

689186

PSA4
Proteasome subunit alpha type-4

5

19

Small-scale

0.912

High

689174

UMP1
Proteasome maturation factor UMP1

4

2

Small-scale

0.881

High

689185

PSA6
Proteasome subunit alpha type-6

3

18

Small-scale

0.839

High

597299

PSA1
Proteasome subunit alpha type-1

2

19

High-throughput

0.776

High

619338

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.776

High

619958

PSB6
Proteasome subunit beta type-6

2

17

High-throughput

0.776

High

625917

PSB2
Proteasome subunit beta type-2

2

20

High-throughput

0.776

High

675449

PSB7
Proteasome subunit beta type-7

2

18

High-throughput

0.776

High

689175

PSB1
Proteasome subunit beta type-1

2

20

High-throughput

0.776

High

689217

POC4
Proteasome chaperone 4

1

1

Small-scale

0.770

High

689165

PRS6A
26S proteasome regulatory subunit 6A

2

20

High-throughput

0.754

High

689167

PRS7
26S proteasome regulatory subunit 7 homolog

2

20

Small-scale

0.754

High

689189

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.751

High

689213

POC3
Proteasome chaperone 3

2

1

Small-scale

0.737

High

689188

BLM10
Proteasome activator BLM10

2

6

Small-scale

0.727

High

632473

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.618

High

689166

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

689172

POC2
Proteasome assembly chaperone 2

1

1

High-throughput

0.618

High

689187

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

689194

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

689203

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

689219

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

689159

RPN2
26S proteasome regulatory subunit RPN2

2

20

Small-scale

0.595

High

689177

ECM29
Proteasome component ECM29

2

8

High-throughput

0.584

High

689178

RPN1
26S proteasome regulatory subunit RPN1

2

20

Small-scale

0.584

High

689214

RPN8
26S proteasome regulatory subunit RPN8

2

16

Small-scale

0.584

High

689218

RPN5
26S proteasome regulatory subunit RPN5

2

19

Small-scale

0.584

High

689208

POC1
Proteasome chaperone 1

1

1

High-throughput

0.553

High

636215

FUB1
Silencing boundary-establishment protein FUB1

2

1

Small-scale

0.533

High

618821

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

655013

CIN8
Kinesin-like protein CIN8

1

5

High-throughput

0.515

High

610953

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.513

High

420247

CALM
Calmodulin

1

1

Small-scale

0.512

High

689169

NOT4
General negative regulator of transcription subunit 4

1

2

High-throughput

0.501

High

689191

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

6

High-throughput

0.501

High

689195

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.489

High

141834

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

406877

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

627805

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

657124

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

5

High-throughput

0.479

High

661608

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

689158

RPN12
26S proteasome regulatory subunit RPN12

1

3

High-throughput

0.479

High

689162

RAD23
UV excision repair protein RAD23

1

20

High-throughput

0.479

High

689163

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

689171

CENPA
Histone H3-like centromeric protein CSE4

1

3

High-throughput

0.479

High

689180

RPN10
26S proteasome regulatory subunit RPN10

1

10

High-throughput

0.479

High

689184

RPN3
26S proteasome regulatory subunit RPN3

1

7

High-throughput

0.479

High

689190

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

1

8

High-throughput

0.479

High

689199

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

689201

H3
Histone H3

1

3

High-throughput

0.479

High

689205

TOM1
E3 ubiquitin-protein ligase TOM1

1

9

High-throughput

0.479

High

689206

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

689207

RPN9
26S proteasome regulatory subunit RPN9

1

10

High-throughput

0.479

High

689209

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

689220

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

689221

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.479

High

689182

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.470

High

550528

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

633834

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.458

High

689168

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

689181

CENPN
Inner kinetochore subunit CHL4

1

0

High-throughput

0.458

High

689193

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.458

High

689196

CWC24
Pre-mRNA-splicing factor CWC24

1

0

High-throughput

0.458

High

689197

CAF40
Protein CAF40

1

0

High-throughput

0.458

High

689210

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

689216

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

689160

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

689161

HSP79
Heat shock protein homolog SSE2

1

8

High-throughput

0.445

High

413372

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

543379

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.437

High

638676

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

689164

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

689173

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

689183

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

689202

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

689212

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.437

High

689215

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

689204

SPP2
Pre-mRNA-splicing factor SPP2

1

0

High-throughput

0.269

Low

689211

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.265

Low

141217

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

357231

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

407796

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

425823

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

479983

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480546

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

631736

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

645319

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

689170

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

689176

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

689179

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

689192

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

689200

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

689198

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024