Protein: EI2BE
Translation initiation factor eIF2B subunit epsilon (GCD complex subunit GCD6) (Guanine nucleotide exchange factor subunit GCD6) (eIF2B GDP-GTP exchange factor subunit epsilon)

Gene: EI2BE, GCD6
Organism: Saccharomyces cerevisiae S288C
Interactions: 84
UniProt ID: P32501

Gene Ontology (top 5):
GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691728

EI2BB
Translation initiation factor eIF2B subunit beta

14

14

Small-scale

0.983

High

521177

EI2BD
Translation initiation factor eIF2B subunit delta

12

14

Small-scale

0.981

High

539961

EI2BA
Translation initiation factor eIF2B subunit alpha

10

14

Small-scale

0.973

High

691740

IF5
Eukaryotic translation initiation factor 5

2

11

Small-scale

0.768

High

446977

EI2BG
Translation initiation factor eIF2B subunit gamma

16

15

Small-scale

0.763

High

447170

IF2B
Eukaryotic translation initiation factor 2 subunit beta

12

4

Small-scale

0.758

High

593828

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

11

1

Small-scale

0.757

High

690896

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

9

8

Small-scale

0.752

High

691727

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

17

High-throughput

0.665

High

410339

SC160
Protein SCP160

2

1

High-throughput

0.588

High

691752

IST1
Vacuolar protein sorting-associated protein IST1

2

1

High-throughput

0.588

High

627824

SIS1
Protein SIS1

2

5

High-throughput

0.571

High

691738

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

2

1

Small-scale

0.560

High

675892

XPO1
Exportin-1

1

7

High-throughput

0.536

High

691220

MKK2
MAP kinase kinase MKK2/SSP33

1

4

High-throughput

0.536

High

691751

FMP48
Probable serine/threonine-protein kinase FMP48

1

1

High-throughput

0.536

High

691758

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

691762

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.536

High

691770

YGK3
Glycogen synthase kinase-3 homolog YGK3

1

2

High-throughput

0.536

High

691767

CYK3
Cytokinesis protein 3

1

0

High-throughput

0.518

High

624280

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

1

0

High-throughput

0.513

High

604519

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

3

High-throughput

0.489

High

615130

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.489

High

691737

TAF5
Transcription initiation factor TFIID subunit 5

1

4

High-throughput

0.489

High

691755

MPS1
Serine/threonine-protein kinase MPS1

1

3

High-throughput

0.489

High

691734

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.481

High

691732

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

Small-scale

0.480

High

141222

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

383018

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

402910

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

4

Small-scale

0.479

High

405502

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

406889

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

407802

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

408305

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.479

High

413381

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

425829

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

470933

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

472084

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

479989

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

480552

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

482148

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

631743

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

645325

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

664704

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

691731

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.479

High

691733

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

691735

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

691736

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

691741

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

691744

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

691746

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

691749

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

691754

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

691759

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

691761

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

691763

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

691766

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

691768

MCA1
Metacaspase-1

1

1

High-throughput

0.479

High

691769

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

691760

ESP1
Separin

1

0

High-throughput

0.458

High

367861

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

490656

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

633046

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

691729

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

691745

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

691730

TOR2
Serine/threonine-protein kinase TOR2

1

4

High-throughput

0.439

High

356331

H4
Histone H4

1

1

High-throughput

0.437

High

606587

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.437

High

638682

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

661651

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

691757

H3
Histone H3

1

1

High-throughput

0.437

High

691765

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.437

High

691743

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

691747

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

691742

SPT8
Transcription factor SPT8

1

1

High-throughput

0.407

High

691764

TAF9
Transcription initiation factor TFIID subunit 9

1

1

High-throughput

0.407

High

691771

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.407

High

576170

SPO7
Sporulation-specific protein SPO7

2

0

High-throughput

0.307

High

691748

NOP9
Nucleolar protein 9

1

0

High-throughput

0.279

Low

691756

ACT
Actin

1

0

High-throughput

0.269

Low

691753

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

691739

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low

691750

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024