Protein: DRS1
ATP-dependent RNA helicase DRS1 (EC 3.6.4.13) (Deficiency of ribosomal subunits protein 1)

Gene: DRS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 155
UniProt ID: P32892

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

699752

DBP10
ATP-dependent RNA helicase DBP10

4

16

High-throughput

0.899

High

699678

CIC1
Proteasome-interacting protein CIC1

4

3

High-throughput

0.886

High

699654

DRS1
ATP-dependent RNA helicase DRS1

3

16

High-throughput

0.834

High

699721

HAS1
ATP-dependent RNA helicase HAS1

3

15

High-throughput

0.827

High

638694

SPB4
ATP-dependent rRNA helicase SPB4

2

19

High-throughput

0.754

High

699671

NOP4
Nucleolar protein 4

6

13

Small-scale

0.737

High

699703

NSA1
Ribosome biogenesis protein NSA1

7

1

Small-scale

0.736

High

699691

RLP7
Ribosome biogenesis protein RLP7

5

11

Small-scale

0.716

High

699706

PESC
Pescadillo homolog

5

5

Small-scale

0.714

High

699670

RPF2
Ribosome biogenesis protein RPF2

5

1

Small-scale

0.709

High

699745

YTM1
Ribosome biogenesis protein YTM1

5

20

Small-scale

0.709

High

699684

NOC2
Nucleolar complex protein 2

5

2

Small-scale

0.704

High

699679

SSF1
Ribosome biogenesis protein SSF1

5

7

Small-scale

0.703

High

699695

LOC1
60S ribosomal subunit assembly/export protein LOC1

4

1

High-throughput

0.702

High

699727

ERB1
Ribosome biogenesis protein ERB1

4

18

High-throughput

0.699

High

699753

IF6
Eukaryotic translation initiation factor 6

4

2

Small-scale

0.694

High

699692

NOP2
25S rRNA

4

10

Small-scale

0.691

High

699710

NOP15
Ribosome biogenesis protein 15

4

20

High-throughput

0.691

High

699750

MAK21
Ribosome biogenesis protein MAK21

4

14

High-throughput

0.680

High

699666

EBP2
rRNA-processing protein EBP2

3

3

High-throughput

0.646

High

699687

NSA2
Ribosome biogenesis protein NSA2

3

2

High-throughput

0.646

High

699738

NOP12
Nucleolar protein 12

3

20

High-throughput

0.646

High

699717

NOG1
Nucleolar GTP-binding protein 1

3

9

Small-scale

0.640

High

699713

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

2

3

High-throughput

0.619

High

420105

TOP2
DNA topoisomerase 2

1

2

High-throughput

0.618

High

699669

DBP7
ATP-dependent RNA helicase DBP7

1

16

High-throughput

0.618

High

699673

MAK5
ATP-dependent RNA helicase MAK5

1

14

High-throughput

0.618

High

699697

MTR4
ATP-dependent RNA helicase DOB1

1

17

Small-scale

0.618

High

699724

DHR1
Probable ATP-dependent RNA helicase DHR1

1

16

High-throughput

0.618

High

699731

DBP9
ATP-dependent RNA helicase DBP9

1

16

High-throughput

0.618

High

699680

RPF1
Ribosome production factor 1

2

3

High-throughput

0.611

High

699709

NOP13
Nucleolar protein 13

2

19

High-throughput

0.611

High

699725

PUF6
Pumilio homology domain family member 6

2

5

High-throughput

0.611

High

699739

BRX1
Ribosome biogenesis protein BRX1

2

16

High-throughput

0.611

High

594025

MAK11
Protein MAK11

2

20

Small-scale

0.584

High

630853

NLE1
Ribosome assembly protein 4

2

20

Small-scale

0.584

High

699664

RRP1
Ribosomal RNA-processing protein 1

2

8

Small-scale

0.584

High

699675

ENP1
Essential nuclear protein 1

2

7

High-throughput

0.584

High

699707

NOG2
Nucleolar GTP-binding protein 2

2

14

Small-scale

0.584

High

699746

NOP53
Ribosome biogenesis protein NOP53

2

4

High-throughput

0.584

High

490736

HSP71
Heat shock protein SSA1

2

15

High-throughput

0.571

High

699748

SSF2
Ribosome biogenesis protein SSF2

2

7

High-throughput

0.571

High

356360

H4
Histone H4

1

10

High-throughput

0.553

High

557967

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.553

High

604524

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

5

High-throughput

0.553

High

699656

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.553

High

699715

KIN4
Serine/threonine-protein kinase KIN4

1

6

High-throughput

0.536

High

699735

NOP6
Nucleolar protein 6

1

2

High-throughput

0.536

High

699741

HRK1
Serine/threonine-protein kinase HRK1

1

6

High-throughput

0.536

High

339539

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.501

High

412454

KIN28
Serine/threonine-protein kinase KIN28

1

7

High-throughput

0.501

High

412698

KAPA
cAMP-dependent protein kinase type 1

1

12

High-throughput

0.501

High

539330

KSS1
Mitogen-activated protein kinase KSS1

1

6

High-throughput

0.501

High

549991

CSK21
Casein kinase II subunit alpha

1

14

High-throughput

0.501

High

565512

PHO85
Cyclin-dependent protein kinase PHO85

1

9

High-throughput

0.501

High

605507

DBF2
Cell cycle protein kinase DBF2

1

13

High-throughput

0.501

High

614592

KC11
Casein kinase I homolog 1

1

10

High-throughput

0.501

High

664411

HRR25
Casein kinase I homolog HRR25

1

5

High-throughput

0.501

High

691185

MKK1
MAP kinase kinase MKK1/SSP32

1

14

High-throughput

0.501

High

698341

ELM1
Serine/threonine-protein kinase ELM1

1

1

High-throughput

0.501

High

699657

SWE1
Mitosis inhibitor protein kinase SWE1

1

14

High-throughput

0.501

High

699663

HSL1
Probable serine/threonine-protein kinase HSL1

1

7

High-throughput

0.501

High

699676

RCK1
Serine/threonine-protein kinase RCK1

1

10

High-throughput

0.501

High

699682

IPL1
Spindle assembly checkpoint kinase

1

15

High-throughput

0.501

High

699694

CAK1
Serine/threonine-protein kinase CAK1

1

17

High-throughput

0.501

High

699699

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

9

High-throughput

0.501

High

699702

ATG1
Serine/threonine-protein kinase ATG1

1

4

High-throughput

0.501

High

699718

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

17

High-throughput

0.501

High

699719

PKH3
Serine/threonine-protein kinase PKH3

1

16

High-throughput

0.501

High

699720

STE20
Serine/threonine-protein kinase STE20

1

8

High-throughput

0.501

High

699722

SKY1
Serine/threonine-protein kinase SKY1

1

20

High-throughput

0.501

High

699747

YP150
Putative serine/threonine-protein kinase YPL150W

1

4

High-throughput

0.501

High

699751

PKH2
Serine/threonine-protein kinase PKH2

1

18

High-throughput

0.501

High

509411

CDC24
Cell division control protein 24

1

3

High-throughput

0.489

High

699659

DOM34
Protein DOM34

1

1

High-throughput

0.489

High

699696

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.480

High

141236

RS9A
Small ribosomal subunit protein uS4A

1

10

High-throughput

0.479

High

383037

RL25
Large ribosomal subunit protein uL23

1

8

High-throughput

0.479

High

404535

RL7A
Large ribosomal subunit protein uL30A

1

11

High-throughput

0.479

High

405522

RL26A
Large ribosomal subunit protein uL24A

1

9

High-throughput

0.479

High

406916

RS3
Small ribosomal subunit protein uS3

1

9

High-throughput

0.479

High

407817

RS13
Small ribosomal subunit protein uS15

1

7

High-throughput

0.479

High

413402

RS14A
Small ribosomal subunit protein uS11A

1

10

High-throughput

0.479

High

425848

RS19A
Small ribosomal subunit protein eS19A

1

11

High-throughput

0.479

High

480004

RS6A
Small ribosomal subunit protein eS6A

1

10

High-throughput

0.479

High

501198

MAK16
Protein MAK16

1

2

High-throughput

0.479

High

631766

RS2
Small ribosomal subunit protein uS5

1

12

High-throughput

0.479

High

634387

SPB1
27S pre-rRNA

1

10

High-throughput

0.479

High

634535

KRR1
KRR1 small subunit processome component

1

8

High-throughput

0.479

High

644985

RL16A
Large ribosomal subunit protein uL13A

1

10

High-throughput

0.479

High

645340

RS7A
Small ribosomal subunit protein eS7A

1

6

High-throughput

0.479

High

699658

MRT4
Ribosome assembly factor MRT4

1

8

High-throughput

0.479

High

699660

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

2

High-throughput

0.479

High

699662

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

Small-scale

0.479

High

699665

RS27A
Small ribosomal subunit protein eS27A

1

7

High-throughput

0.479

High

699667

RRP14
Ribosomal RNA-processing protein 14

1

1

High-throughput

0.479

High

699668

RL14A
Large ribosomal subunit protein eL14A

1

6

High-throughput

0.479

High

699674

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

699681

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

6

High-throughput

0.479

High

699685

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

699686

NUG1
Nuclear GTP-binding protein NUG1

1

14

High-throughput

0.479

High

699688

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.479

High

699693

UTP10
U3 small nucleolar RNA-associated protein 10

1

5

High-throughput

0.479

High

699701

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.479

High

699708

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

19

High-throughput

0.479

High

699711

RCM1
25S rRNA

1

10

High-throughput

0.479

High

699714

RS15
Small ribosomal subunit protein uS19

1

7

High-throughput

0.479

High

699716

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

699723

RRP17
Ribosomal RNA-processing protein 17

1

1

High-throughput

0.479

High

699726

UTP14
U3 small nucleolar RNA-associated protein 14

1

4

High-throughput

0.479

High

699728

RRP5
rRNA biogenesis protein RRP5

1

16

High-throughput

0.479

High

699730

FKBP4
FK506-binding protein 4

1

6

High-throughput

0.479

High

699732

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

699733

NOC4
Nucleolar complex protein 4

1

14

High-throughput

0.479

High

699736

NOC3
Nucleolar complex-associated protein 3

1

11

High-throughput

0.479

High

699737

RLP24
Ribosome biogenesis protein RLP24

1

5

High-throughput

0.479

High

699742

RS10A
Small ribosomal subunit protein eS10A

1

8

High-throughput

0.479

High

699743

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.479

High

699744

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

699749

YRA1
RNA annealing protein YRA1

1

12

High-throughput

0.479

High

685430

SYKM
Lysine--tRNA ligase, mitochondrial

1

0

Small-scale

0.460

High

446134

MYO1
Myosin-1

1

0

Small-scale

0.458

High

699698

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

687784

MSB2
Signaling mucin MSB2

1

5

Small-scale

0.457

High

478041

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.445

High

493538

HSP72
Heat shock protein SSA2

1

16

High-throughput

0.445

High

510727

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

694369

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

355419

H2B1
Histone H2B.1

1

8

High-throughput

0.437

High

355844

H2B2
Histone H2B.2

1

8

High-throughput

0.437

High

357965

RS17A
Small ribosomal subunit protein eS17A

1

6

High-throughput

0.437

High

392365

H2A2
Histone H2A.2

1

8

High-throughput

0.437

High

408309

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.437

High

470954

RS22A
Small ribosomal subunit protein uS8A

1

9

High-throughput

0.437

High

472102

RL31A
Large ribosomal subunit protein eL31A

1

13

High-throughput

0.437

High

480569

RS8A
Small ribosomal subunit protein eS8A

1

8

High-throughput

0.437

High

482167

RS18A
Small ribosomal subunit protein uS13A

1

8

High-throughput

0.437

High

627858

SIS1
Protein SIS1

1

7

High-throughput

0.437

High

661743

TF2B
Transcription initiation factor IIB

1

7

High-throughput

0.437

High

688169

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

4

High-throughput

0.437

High

699655

RSSA1
Small ribosomal subunit protein uS2A

1

15

High-throughput

0.437

High

699661

RS3A1
Small ribosomal subunit protein eS1A

1

8

High-throughput

0.437

High

699672

GBLP
Small ribosomal subunit protein RACK1

1

20

High-throughput

0.437

High

699677

RS20
Small ribosomal subunit protein uS10

1

11

High-throughput

0.437

High

699683

LAA1
AP-1 accessory protein LAA1

1

6

High-throughput

0.437

High

699689

ULP2
Ubiquitin-like-specific protease 2

1

6

High-throughput

0.437

High

699690

DSN1
Kinetochore-associated protein DSN1

1

5

High-throughput

0.437

High

699700

RS12
Small ribosomal subunit protein eS12

1

6

High-throughput

0.437

High

699705

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.437

High

699712

H3
Histone H3

1

16

High-throughput

0.437

High

699729

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

3

High-throughput

0.437

High

699734

VAM6
Vacuolar morphogenesis protein 6

1

5

High-throughput

0.437

High

699740

SGO1
Shugoshin

1

4

High-throughput

0.437

High

699704

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024