Protein: PRS7
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)

Gene: PRS7, RPT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 203
UniProt ID: P33299

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703894

RPN1
26S proteasome regulatory subunit RPN1

24

20

Small-scale

0.991

High

703948

PRS8
26S proteasome regulatory subunit 8 homolog

18

19

Small-scale

0.987

High

703910

PRS4
26S proteasome regulatory subunit 4 homolog

15

20

Small-scale

0.986

High

703884

HSM3
DNA mismatch repair protein HSM3

14

2

Small-scale

0.986

High

703773

PRS6B
26S proteasome regulatory subunit 6B homolog

15

20

Small-scale

0.984

High

604775

PSB4
Proteasome subunit beta type-4

16

20

Small-scale

0.982

High

703929

PSD10
Probable 26S proteasome regulatory subunit p28

13

11

Small-scale

0.981

High

703566

PRS6A
26S proteasome regulatory subunit 6A

13

20

Small-scale

0.980

High

697067

RAD23
UV excision repair protein RAD23

11

20

Small-scale

0.980

High

703936

PRS10
26S proteasome subunit RPT4

11

19

Small-scale

0.976

High

703961

RPN7
26S proteasome regulatory subunit RPN7

7

20

Small-scale

0.962

High

703926

DSK2
Ubiquitin domain-containing protein DSK2

5

20

Small-scale

0.927

High

703888

PSB1
Proteasome subunit beta type-1

3

20

Small-scale

0.847

High

703908

PSA4
Proteasome subunit alpha type-4

3

20

Small-scale

0.847

High

477201

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

20

Small-scale

0.845

High

703920

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

29

20

Small-scale

0.768

High

447791

CDC6
Cell division control protein 6

2

0

High-throughput

0.761

High

703933

RPN14
26S proteasome regulatory subunit RPN14

10

17

Small-scale

0.756

High

693271

RPN2
26S proteasome regulatory subunit RPN2

11

20

Small-scale

0.755

High

597221

PSA7
Probable proteasome subunit alpha type-7

2

20

Small-scale

0.754

High

597306

PSA1
Proteasome subunit alpha type-1

2

20

Small-scale

0.754

High

619440

PSA2
Proteasome subunit alpha type-2

2

20

High-throughput

0.754

High

625924

PSB2
Proteasome subunit beta type-2

2

20

Small-scale

0.754

High

689167

PSA5
Proteasome subunit alpha type-5

2

20

Small-scale

0.754

High

703897

RPN10
26S proteasome regulatory subunit RPN10

10

12

Small-scale

0.753

High

691456

RPN12
26S proteasome regulatory subunit RPN12

9

6

Small-scale

0.752

High

703921

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

8

14

Small-scale

0.749

High

703971

RPN8
26S proteasome regulatory subunit RPN8

8

15

Small-scale

0.747

High

703976

RPN6
26S proteasome regulatory subunit RPN6

8

20

Small-scale

0.747

High

703974

RPN5
26S proteasome regulatory subunit RPN5

7

20

Small-scale

0.745

High

141843

RPN13
26S proteasome regulatory subunit RPN13

7

2

Small-scale

0.744

High

703978

RUVB2
RuvB-like protein 2

2

7

High-throughput

0.737

High

703958

RPN9
26S proteasome regulatory subunit RPN9

6

13

Small-scale

0.729

High

703905

RPN3
26S proteasome regulatory subunit RPN3

5

13

Small-scale

0.712

High

294112

SEM1
26S proteasome complex subunit SEM1

5

2

Small-scale

0.709

High

703893

ECM29
Proteasome component ECM29

4

9

High-throughput

0.691

High

490761

HSP71
Heat shock protein SSA1

3

9

Small-scale

0.640

High

703913

PSMD9
Probable 26S proteasome regulatory subunit p27

1

9

Small-scale

0.621

High

578522

SEC18
Vesicular-fusion protein SEC18

1

17

High-throughput

0.618

High

619347

PSA3
Proteasome subunit alpha type-3

1

20

High-throughput

0.618

High

619964

PSB6
Proteasome subunit beta type-6

1

20

High-throughput

0.618

High

632478

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.618

High

636575

CDC48
Cell division control protein 48

1

16

Small-scale

0.618

High

675407

PSB5
Proteasome subunit beta type-5

1

20

High-throughput

0.618

High

675456

PSB7
Proteasome subunit beta type-7

1

20

High-throughput

0.618

High

680575

HS104
Heat shock protein 104

1

5

High-throughput

0.618

High

703871

PRS7
26S proteasome regulatory subunit 7 homolog

1

17

Small-scale

0.618

High

703907

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.618

High

703957

RUVB1
RuvB-like protein 1

1

7

High-throughput

0.618

High

339546

CDK1
Cyclin-dependent kinase 1

2

6

Small-scale

0.601

High

526984

TBP
TATA-box-binding protein

2

5

Small-scale

0.585

High

543463

HSC82
ATP-dependent molecular chaperone HSC82

2

11

High-throughput

0.584

High

627874

SIS1
Protein SIS1

2

10

High-throughput

0.584

High

703880

UMP1
Proteasome maturation factor UMP1

2

1

Small-scale

0.584

High

703953

RPN4
Protein RPN4

2

1

Small-scale

0.584

High

703966

RIX7
Ribosome biogenesis ATPase RIX7

1

16

High-throughput

0.575

High

493558

HSP72
Heat shock protein SSA2

2

9

Small-scale

0.571

High

520323

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

2

2

Small-scale

0.571

High

416771

CDC31
Cell division control protein 31

1

7

Small-scale

0.561

High

425324

PHO4
Phosphate system positive regulatory protein PHO4

1

2

Small-scale

0.561

High

587302

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

Small-scale

0.561

High

701353

SC61A
Protein transport protein SEC61

2

2

Small-scale

0.543

High

703931

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.537

High

440876

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

1

High-throughput

0.536

High

675919

XPO1
Exportin-1

1

2

High-throughput

0.536

High

693092

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

5

Small-scale

0.536

High

703935

BUD32
EKC/KEOPS complex subunit BUD32

1

1

High-throughput

0.536

High

703979

YO098
Uncharacterized protein YOL098C

1

1

High-throughput

0.536

High

703954

ESC1
Silent chromatin protein ESC1

2

5

High-throughput

0.533

High

700308

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.521

High

703887

LEO1
RNA polymerase-associated protein LEO1

1

1

Small-scale

0.515

High

703945

CTR9
RNA polymerase-associated protein CTR9

1

5

Small-scale

0.515

High

703895

CIC1
Proteasome-interacting protein CIC1

1

0

Small-scale

0.513

High

703917

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

703969

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

Small-scale

0.513

High

381538

GAL4
Regulatory protein GAL4

1

2

Small-scale

0.501

High

703885

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.493

High

703883

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.489

High

703922

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.489

High

594121

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

Small-scale

0.480

High

141241

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

366045

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.479

High

367908

EF1A
Elongation factor 1-alpha

1

4

Small-scale

0.479

High

406925

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

454904

CDC16
Anaphase-promoting complex subunit CDC16

1

8

Small-scale

0.479

High

560616

BIP
Endoplasmic reticulum chaperone BiP

1

8

Small-scale

0.479

High

566154

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

606606

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.479

High

624679

CG22
G2/mitotic-specific cyclin-2

1

2

Small-scale

0.479

High

631772

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

636120

NOT1
General negative regulator of transcription subunit 1

1

1

Small-scale

0.479

High

661770

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

688175

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

3

High-throughput

0.479

High

691010

HOG1
Mitogen-activated protein kinase HOG1

1

9

High-throughput

0.479

High

691956

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

2

High-throughput

0.479

High

694386

HSP7F
Heat shock protein homolog SSE1

1

16

Small-scale

0.479

High

700820

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

703876

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

703877

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.479

High

703878

POC2
Proteasome assembly chaperone 2

1

1

High-throughput

0.479

High

703879

GBLP
Small ribosomal subunit protein RACK1

1

13

High-throughput

0.479

High

703890

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

703896

WSS1
DNA-dependent metalloprotease WSS1

1

1

Small-scale

0.479

High

703903

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

High-throughput

0.479

High

703904

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

1

High-throughput

0.479

High

703919

BLM10
Proteasome activator BLM10

1

5

High-throughput

0.479

High

703923

MPS3
Spindle pole body assembly component MPS3

1

2

High-throughput

0.479

High

703925

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

703927

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

703928

VATG
V-type proton ATPase subunit G

1

2

High-throughput

0.479

High

703932

INO80
Chromatin-remodeling ATPase INO80

1

5

Small-scale

0.479

High

703938

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

11

High-throughput

0.479

High

703940

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.479

High

703944

H3
Histone H3

1

7

High-throughput

0.479

High

703946

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

9

Small-scale

0.479

High

703947

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

703949

PNG1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

2

Small-scale

0.479

High

703951

ESP1
Separin

1

1

High-throughput

0.479

High

703952

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

703956

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

2

High-throughput

0.479

High

703960

POC1
Proteasome chaperone 1

1

1

High-throughput

0.479

High

703962

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

703963

TFC6
Transcription factor tau 91 kDa subunit

1

2

High-throughput

0.479

High

703965

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

703967

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

12

Small-scale

0.479

High

703970

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.479

High

703875

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

703881

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

703889

STS1
Tethering factor for nuclear proteasome STS1

1

0

Small-scale

0.458

High

703942

UBX4
UBX domain-containing protein 4

1

0

Small-scale

0.458

High

703955

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

703964

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

703968

CUE5
Ubiquitin-binding protein CUE5

1

0

Small-scale

0.458

High

703975

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.458

High

389071

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

412545

CDC7
Cell division control protein 7

1

20

Small-scale

0.445

High

420481

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

1

1

High-throughput

0.445

High

510752

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

555939

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

579411

GBB
Guanine nucleotide-binding protein subunit beta

1

12

High-throughput

0.445

High

608686

UBA1
Ubiquitin-activating enzyme E1 1

1

2

High-throughput

0.445

High

632559

RAD51
DNA repair protein RAD51

1

1

High-throughput

0.445

High

648126

KCC1
Calcium/calmodulin-dependent protein kinase I

1

4

High-throughput

0.445

High

657220

URA7
CTP synthase 1

1

4

High-throughput

0.445

High

687914

IMB3
Importin subunit beta-3

1

3

High-throughput

0.445

High

690069

APE2
Aminopeptidase 2, mitochondrial

1

1

High-throughput

0.445

High

691518

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.445

High

693386

SMI1
Cell wall assembly regulator SMI1

1

1

High-throughput

0.445

High

693618

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

11

Small-scale

0.445

High

703891

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

703899

TCPD
T-complex protein 1 subunit delta

1

7

High-throughput

0.445

High

703906

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

703914

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

703924

GPN1
GPN-loop GTPase 1

1

1

High-throughput

0.445

High

703959

PDR15
ATP-dependent permease PDR15

1

1

High-throughput

0.445

High

703977

AHA1
Hsp90 co-chaperone AHA1

1

3

High-throughput

0.445

High

703939

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

357971

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

383044

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405529

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

413409

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

425856

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

470958

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

472109

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

480011

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

480576

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

541657

SEC63
Protein translocation protein SEC63

1

1

Small-scale

0.437

High

561116

CDC23
Anaphase-promoting complex subunit CDC23

1

7

Small-scale

0.437

High

634539

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

636219

FUB1
Silencing boundary-establishment protein FUB1

1

1

High-throughput

0.437

High

703873

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

703901

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

703909

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

2

Small-scale

0.437

High

703912

MLP2
Protein MLP2

1

7

High-throughput

0.437

High

703918

UTP10
U3 small nucleolar RNA-associated protein 10

1

3

High-throughput

0.437

High

703972

RS10A
Small ribosomal subunit protein eS10A

1

5

High-throughput

0.437

High

592858

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

625803

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.426

High

703900

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

703911

DLS1
Protein DLS1

1

0

High-throughput

0.426

High

703934

RAGCD
GTP-binding protein GTR2

1

0

High-throughput

0.426

High

520241

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

2

High-throughput

0.407

High

691777

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.407

High

703872

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

1

High-throughput

0.407

High

703898

GGC1
Mitochondrial GTP/GDP carrier protein 1

1

2

High-throughput

0.407

High

703916

COPB
Coatomer subunit beta

1

4

High-throughput

0.407

High

703937

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.407

High

703941

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.407

High

703943

TMEDA
Endoplasmic reticulum vesicle protein 25

1

4

High-throughput

0.407

High

703950

TFB2
General transcription and DNA repair factor IIH subunit TFB2

1

0

Small-scale

0.261

Low

601685

SEC62
Translocation protein SEC62

1

0

Small-scale

0.249

Low

703874

SC61G
Protein transport protein SSS1

1

0

Small-scale

0.249

Low

703886

CUE1
Coupling of ubiquitin conjugation to ER degradation protein 1

1

0

Small-scale

0.249

Low

703892

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.249

Low

703902

SEC72
Translocation protein SEC72

1

0

Small-scale

0.249

Low

703930

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.249

Low

703980

OS9
Protein OS-9 homolog

1

0

Small-scale

0.249

Low

427220

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

659140

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.232

Low

703882

FTH1
Iron transporter FTH1

1

0

High-throughput

0.232

Low

703915

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.232

Low

703973

FSF1
Sideroflexin FSF1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024