Protein: ISW1
ISWI chromatin-remodeling complex ATPase ISW1 (EC 3.6.4.-)

Gene: ISW1
Organism: Saccharomyces cerevisiae S288C
Interactions: 164
UniProt ID: P38144

Gene Ontology (top 5):
GO:0000182 - rDNA binding
GO:0000976 - transcription cis-regulatory region binding
GO:0001178 - regulation of transcriptional start site selection at RNA polymerase II promoter
GO:0004386 - helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744878

IOC3
ISWI one complex protein 3

12

1

Small-scale

0.983

High

356424

H4
Histone H4

6

16

Small-scale

0.937

High

744893

H3
Histone H3

6

20

Small-scale

0.935

High

355460

H2B1
Histone H2B.1

5

20

Small-scale

0.915

High

392403

H2A2
Histone H2A.2

5

20

Small-scale

0.912

High

697384

CHD1
Chromo domain-containing protein 1

4

17

Small-scale

0.892

High

355873

H2B2
Histone H2B.2

4

20

Small-scale

0.875

High

687690

BTAF1
TATA-binding protein-associated factor MOT1

3

18

Small-scale

0.855

High

744923

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

3

17

Small-scale

0.855

High

744936

H2AZ
Histone H2A.Z

3

20

High-throughput

0.817

High

744933

ARP7
Actin-related protein 7

2

20

High-throughput

0.789

High

429689

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

3

High-throughput

0.759

High

744924

IOC2
ISWI one complex protein 2

6

1

Small-scale

0.733

High

744908

IOC4
ISWI one complex protein 4

5

1

Small-scale

0.714

High

744904

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.691

High

744919

RSC58
Chromatin structure-remodeling complex protein RSC58

4

1

High-throughput

0.687

High

744920

ESC8
Protein ESC8

4

1

High-throughput

0.683

High

744888

ITC1
Imitation switch two complex protein 1

3

17

High-throughput

0.667

High

744913

SGD1
Suppressor of glycerol defect protein 1

1

8

High-throughput

0.665

High

635505

RSC6
Chromatin structure-remodeling complex protein RSC6

3

18

High-throughput

0.662

High

609080

SIN3
Transcriptional regulatory protein SIN3

3

15

High-throughput

0.657

High

744895

RSC4
Chromatin structure-remodeling complex subunit RSC4

3

20

High-throughput

0.657

High

392106

H2A1
Histone H2A.1

1

20

Small-scale

0.647

High

744875

ATAD2
ATPase histone chaperone YTA7

3

5

High-throughput

0.633

High

698650

RSC7
Chromatin structure-remodeling complex subunit RSC7

2

2

High-throughput

0.621

High

744879

RSC8
Chromatin structure-remodeling complex protein RSC8

2

20

High-throughput

0.621

High

744916

RSC2
Chromatin structure-remodeling complex subunit RSC2

2

20

High-throughput

0.621

High

558022

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.618

High

606622

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.618

High

696200

STH1
Nuclear protein STH1/NPS1

1

17

High-throughput

0.618

High

744926

RRP6
Exosome complex exonuclease RRP6

1

1

Small-scale

0.618

High

514251

NHP6B
Non-histone chromosomal protein 6B

2

20

High-throughput

0.588

High

744885

RFX1
RFX-like DNA-binding protein RFX1

2

6

High-throughput

0.588

High

744902

NHP10
Non-histone protein 10

2

20

High-throughput

0.588

High

744935

CMR1
DNA damage-binding protein CMR1

2

18

High-throughput

0.584

High

744912

SWR1
Helicase SWR1

1

16

High-throughput

0.575

High

710437

SAS3
Histone acetyltransferase SAS3

2

7

High-throughput

0.571

High

716227

SPT10
Protein SPT10

2

3

High-throughput

0.571

High

744874

RT106
Histone chaperone RTT106

2

2

High-throughput

0.571

High

744880

TAF1
Transcription initiation factor TFIID subunit 1

2

3

High-throughput

0.571

High

744891

APJ1
J domain-containing protein APJ1

2

7

High-throughput

0.571

High

744899

HOS3
Histone deacetylase HOS3

2

20

High-throughput

0.571

High

744910

POB3
FACT complex subunit POB3

2

9

High-throughput

0.571

High

599454

VPS1
Vacuolar protein sorting-associated protein 1

2

3

High-throughput

0.567

High

493764

HSP72
Heat shock protein SSA2

2

18

High-throughput

0.552

High

511033

SSB1
Ribosome-associated molecular chaperone SSB1

2

18

High-throughput

0.552

High

667853

MCM5
Minichromosome maintenance protein 5

2

4

High-throughput

0.552

High

744873

SSB2
Ribosome-associated molecular chaperone SSB2

2

18

High-throughput

0.552

High

489671

MPPB
Mitochondrial-processing peptidase subunit beta

2

1

High-throughput

0.537

High

744896

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.536

High

744905

HMO1
High mobility group protein 1

1

20

High-throughput

0.536

High

744872

SCC4
MAU2 chromatid cohesion factor homolog

2

3

Small-scale

0.533

High

701397

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.517

High

744864

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

High-throughput

0.517

High

388099

TOP1
DNA topoisomerase 1

1

7

High-throughput

0.515

High

744917

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.513

High

488489

PRI1
DNA primase small subunit

1

0

High-throughput

0.493

High

530008

STE12
Protein STE12

1

0

High-throughput

0.493

High

744897

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.493

High

605632

KIN3
Serine/threonine-protein kinase KIN3

1

3

High-throughput

0.481

High

688876

SMY1
Kinesin-related protein SMY1

1

7

High-throughput

0.481

High

702656

TYE7
Transcription factor TYE7

1

1

High-throughput

0.481

High

705985

NIP80
Protein NIP100

1

11

High-throughput

0.481

High

707987

NUF2
Kinetochore protein NUF2

1

2

High-throughput

0.481

High

731298

DYHC
Dynein heavy chain, cytoplasmic

1

4

High-throughput

0.481

High

406996

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

420115

TOP2
DNA topoisomerase 2

1

9

High-throughput

0.479

High

565156

CBF1
Centromere-binding protein 1

1

10

Small-scale

0.479

High

607262

RFA1
Replication factor A protein 1

1

11

Small-scale

0.479

High

627952

SIS1
Protein SIS1

1

5

High-throughput

0.479

High

662012

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

664787

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

688208

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

692762

SPT16
FACT complex subunit SPT16

1

5

High-throughput

0.479

High

698777

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

11

High-throughput

0.479

High

715673

TAF14
Transcription initiation factor TFIID subunit 14

1

3

Small-scale

0.479

High

716410

SPT21
Protein SPT21

1

2

High-throughput

0.479

High

742752

GBLP
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.479

High

744860

LDB7
Chromatin structure-remodeling complex protein RSC14

1

1

High-throughput

0.479

High

744861

RFC1
Replication factor C subunit 1

1

6

High-throughput

0.479

High

744876

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

744898

IMA1
Importin subunit alpha

1

20

Small-scale

0.479

High

744900

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

1

High-throughput

0.479

High

744906

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

744914

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

10

High-throughput

0.479

High

744921

SGO1
Shugoshin

1

1

High-throughput

0.479

High

744925

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

744927

SCC1
Sister chromatid cohesion protein 1

1

6

High-throughput

0.479

High

744928

RIO1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.479

High

744929

SMT3
Ubiquitin-like protein SMT3

1

13

High-throughput

0.479

High

744937

MEX67
mRNA export factor MEX67

1

2

Small-scale

0.479

High

744938

HTL1
High temperature lethal protein 1

1

1

High-throughput

0.479

High

744882

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

612168

APN1
Apurinic-apyrimidinic endonuclease 1

1

0

High-throughput

0.458

High

744889

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.458

High

744907

LRS4
Monopolin complex subunit LRS4

1

0

Small-scale

0.458

High

744915

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

366171

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.445

High

419332

HAP2
Transcriptional activator HAP2

1

3

High-throughput

0.445

High

450019

HSP73
Heat shock protein SSA3

1

18

High-throughput

0.445

High

457021

SWI6
Regulatory protein SWI6

1

11

High-throughput

0.445

High

490987

HSP71
Heat shock protein SSA1

1

18

High-throughput

0.445

High

514173

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.445

High

515056

MCM1
Pheromone receptor transcription factor

1

7

High-throughput

0.445

High

597828

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.445

High

605227

AFT1
Iron-regulated transcriptional activator AFT1

1

1

High-throughput

0.445

High

628861

SWI4
Regulatory protein SWI4

1

11

High-throughput

0.445

High

633157

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.445

High

640918

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.445

High

689869

ASF1
Histone chaperone ASF1

1

9

High-throughput

0.445

High

694548

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

705091

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

705878

IXR1
Intrastrand cross-link recognition protein

1

20

High-throughput

0.445

High

706958

MSN2
Zinc finger protein MSN2

1

12

High-throughput

0.445

High

733239

SET3
SET domain-containing protein 3

1

16

High-throughput

0.445

High

744863

SSZ1
Ribosome-associated complex subunit SSZ1

1

14

High-throughput

0.445

High

744865

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

20

High-throughput

0.445

High

744867

CAJ1
Protein CAJ1

1

4

High-throughput

0.445

High

744868

XDJ1
DnaJ protein homolog XDJ1

1

7

High-throughput

0.445

High

744870

MBP1
Transcription factor MBP1

1

12

High-throughput

0.445

High

744871

HSP7E
Heat shock protein SSC3, mitochondrial

1

17

High-throughput

0.445

High

744881

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

20

High-throughput

0.445

High

744887

HOS2
Probable histone deacetylase HOS2

1

20

High-throughput

0.445

High

744901

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.445

High

744903

GIS1
Transcriptional activator/repressor GIS1

1

8

High-throughput

0.445

High

744911

RCO1
Transcriptional regulatory protein RCO1

1

20

High-throughput

0.445

High

744918

BRE1
E3 ubiquitin-protein ligase BRE1

1

15

High-throughput

0.445

High

744930

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

744934

RLF2
Chromatin assembly factor 1 subunit p90

1

12

High-throughput

0.445

High

744866

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.439

High

141288

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.437

High

358027

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

383097

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

405578

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.437

High

425910

RS19A
Small ribosomal subunit protein eS19A

1

6

High-throughput

0.437

High

471014

RS22A
Small ribosomal subunit protein uS8A

1

5

High-throughput

0.437

High

472154

RL31A
Large ribosomal subunit protein eL31A

1

4

High-throughput

0.437

High

480063

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.437

High

480628

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

482227

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.437

High

631831

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.437

High

700365

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

700854

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

706229

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.437

High

729868

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.437

High

744862

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.437

High

744869

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

744884

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.437

High

744894

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

744922

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

612228

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

691898

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

744892

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.426

High

367980

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

399225

FUR4
Uracil permease

1

1

High-throughput

0.407

High

541690

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.407

High

693623

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.407

High

744883

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.407

High

744886

CCH1
Calcium-channel protein CCH1

1

2

High-throughput

0.407

High

744932

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

744877

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

744890

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.232

Low

744909

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

744931

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024