Protein: CYFP2
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)

Gene: CYFP2, Cyfip2
Organism: Mus musculus
Interactions: 187
UniProt ID: Q5SQX6

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0030833 - regulation of actin filament polymerization
GO:0031175 - neuron projection development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1210215

ABI1
Abl interactor 1

3

11

High-throughput

0.861

High

704280

NCKP1
Nck-associated protein 1

2

6

High-throughput

0.789

High

1210178

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

1

High-throughput

0.789

High

1210231

WASF1
Actin-binding protein WASF1

2

13

High-throughput

0.789

High

976080

ABI2
Abl interactor 2

2

18

High-throughput

0.705

High

1190132

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.691

High

1210154

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

1

High-throughput

0.618

High

1210193

WASF2
Actin-binding protein WASF2

1

12

High-throughput

0.618

High

1193725

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

7

High-throughput

0.611

High

1210253

DLGP1
Disks large-associated protein 1

2

2

High-throughput

0.611

High

1210161

DLG4
Disks large homolog 4

2

3

High-throughput

0.601

High

1208427

COBL
Protein cordon-bleu

1

0

High-throughput

0.586

High

104535

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

2

High-throughput

0.558

High

92678

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

5

High-throughput

0.536

High

236976

CNTP1
Contactin-associated protein 1

1

1

High-throughput

0.536

High

548948

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

5

High-throughput

0.536

High

580365

CADH2
Cadherin-2

1

1

High-throughput

0.536

High

1000383

CAD10
Cadherin-10

1

1

High-throughput

0.536

High

1013583

TNIK
Traf2 and NCK-interacting protein kinase

1

3

High-throughput

0.536

High

1036061

CTNB1
Catenin beta-1

1

3

High-throughput

0.536

High

1210163

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

High-throughput

0.536

High

1210173

CSKI1
Caskin-1

1

1

High-throughput

0.536

High

1210188

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

3

High-throughput

0.536

High

1210220

NEK9
Serine/threonine-protein kinase Nek9

1

2

High-throughput

0.536

High

1210223

DP13A
DCC-interacting protein 13-alpha

1

1

High-throughput

0.536

High

1210239

MYO5A
Unconventional myosin-Va

1

1

High-throughput

0.536

High

1210260

TSC1
Hamartin

1

1

High-throughput

0.536

High

59742

SKT
Sickle tail protein

1

0

High-throughput

0.513

High

1210179

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

1210207

NLGN3
Neuroligin-3

1

0

High-throughput

0.513

High

1210212

PEX5R
PEX5-related protein

1

0

High-throughput

0.513

High

73122

NHSL2
NHS-like protein 2

1

4

High-throughput

0.489

High

86308

CTTB2
Cortactin-binding protein 2

1

4

High-throughput

0.489

High

204228

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

5

High-throughput

0.489

High

604458

AP2A1
AP-2 complex subunit alpha-1

1

3

High-throughput

0.489

High

704214

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

5

High-throughput

0.489

High

810521

DYN1
Dynamin-1

1

5

High-throughput

0.489

High

858168

AINX
Alpha-internexin

1

4

High-throughput

0.489

High

1064107

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

2

High-throughput

0.489

High

1210166

Q68FG2
Spectrin beta chain

1

8

High-throughput

0.489

High

73164

DLGP4
Disks large-associated protein 4

1

2

High-throughput

0.479

High

97789

PRR12
Proline-rich protein 12

1

1

High-throughput

0.479

High

530815

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.479

High

704265

CELF1
CUGBP Elav-like family member 1

1

1

High-throughput

0.479

High

834256

MATK
Megakaryocyte-associated tyrosine-protein kinase

1

9

High-throughput

0.479

High

977631

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

2

High-throughput

0.479

High

1022013

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

3

High-throughput

0.479

High

1190585

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

7

High-throughput

0.479

High

1204106

MYO16
Unconventional myosin-XVI

1

5

High-throughput

0.479

High

1210156

SRC8
Src substrate cortactin

1

5

High-throughput

0.479

High

1210164

SRBS1
Sorbin and SH3 domain-containing protein 1

1

11

High-throughput

0.479

High

1210169

NIPBL
Nipped-B-like protein

1

3

High-throughput

0.479

High

1210172

NEST
Nestin

1

4

High-throughput

0.479

High

1210176

NEB2
Neurabin-2

1

5

High-throughput

0.479

High

1210182

MFN2
Mitofusin-2

1

1

High-throughput

0.479

High

1210184

DGKZ
Diacylglycerol kinase zeta

1

1

High-throughput

0.479

High

1210187

RHG33
Rho GTPase-activating protein 33

1

5

High-throughput

0.479

High

1210192

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

3

High-throughput

0.479

High

1210199

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

9

High-throughput

0.479

High

1210202

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

High-throughput

0.479

High

1210205

TAOK3
Serine/threonine-protein kinase TAO3

1

1

High-throughput

0.479

High

1210208

MAP1S
Microtubule-associated protein 1S

1

1

High-throughput

0.479

High

1210209

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

1210210

MYO9A
Unconventional myosin-IXa

1

2

High-throughput

0.479

High

1210218

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1210219

AGO1
Protein argonaute-1

1

1

High-throughput

0.479

High

1210235

BRK1
Protein BRICK1

1

3

High-throughput

0.479

High

1210241

TARA
TRIO and F-actin-binding protein

1

2

High-throughput

0.479

High

1210267

SPAST
Spastin

1

1

High-throughput

0.479

High

59102

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

0

High-throughput

0.458

High

205036

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.458

High

236348

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

237302

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.458

High

267220

DIAP2
Protein diaphanous homolog 2

1

0

High-throughput

0.458

High

571214

CALR
Calreticulin

1

0

High-throughput

0.458

High

571262

AT1B2
Sodium/potassium-transporting ATPase subunit beta-2

1

0

High-throughput

0.458

High

615465

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.458

High

655046

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

878730

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.458

High

946298

STRN4
Striatin-4

1

0

High-throughput

0.458

High

947849

IF5
Eukaryotic translation initiation factor 5

1

0

High-throughput

0.458

High

992435

GBG3

1

0

High-throughput

0.458

High

999805

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.458

High

1178520

CYTSA
Cytospin-A

1

0

High-throughput

0.458

High

1189399

ZC3HF
Zinc finger CCCH domain-containing protein 15

1

0

High-throughput

0.458

High

1191333

CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2

1

0

High-throughput

0.458

High

1210160

ZN148
Zinc finger protein 148

1

0

High-throughput

0.458

High

1210168

ABLM3
Actin-binding LIM protein 3

1

0

High-throughput

0.458

High

1210170

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.458

High

1210183

PUM1
Pumilio homolog 1

1

0

High-throughput

0.458

High

1210190

SPE39
Spermatogenesis-defective protein 39 homolog

1

0

High-throughput

0.458

High

1210196

ZN787
Zinc finger protein 787

1

0

High-throughput

0.458

High

1210204

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.458

High

1210211

VASH1
Tubulinyl-Tyr carboxypeptidase 1

1

0

High-throughput

0.458

High

1210214

SCAI
Protein SCAI

1

0

High-throughput

0.458

High

1210216

PABP2
Polyadenylate-binding protein 2

1

0

High-throughput

0.458

High

1210221

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

1210222

PLCL2
Inactive phospholipase C-like protein 2

1

0

High-throughput

0.458

High

1210225

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.458

High

1210226

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

1210230

TCF25
Ribosome quality control complex subunit TCF25

1

0

High-throughput

0.458

High

1210234

5MP1
eIF5-mimic protein 1

1

0

High-throughput

0.458

High

1210236

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1210238

MTA3
Metastasis-associated protein MTA3

1

0

High-throughput

0.458

High

1210243

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.458

High

1210244

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.458

High

1210254

PHF6
PHD finger protein 6

1

0

High-throughput

0.458

High

1210255

SUN1
SUN domain-containing protein 1

1

0

High-throughput

0.458

High

1210257

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

High-throughput

0.458

High

1210262

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.458

High

1210264

SEM7A
Semaphorin-7A

1

0

High-throughput

0.458

High

1210268

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.458

High

1210269

MBD3
Methyl-CpG-binding domain protein 3

1

0

High-throughput

0.458

High

777888

FMR1
Fragile X messenger ribonucleoprotein 1

1

9

High-throughput

0.445

High

86348

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

9

High-throughput

0.437

High

616119

KS6A3
Ribosomal protein S6 kinase alpha-3

1

1

High-throughput

0.437

High

932613

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

4

High-throughput

0.437

High

940741

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

1

High-throughput

0.437

High

1197949

KCTD8
BTB/POZ domain-containing protein KCTD8

1

3

High-throughput

0.437

High

1210159

ARHG1
Rho guanine nucleotide exchange factor 1

1

2

High-throughput

0.437

High

1210162

DAG1
Dystroglycan 1

1

2

High-throughput

0.437

High

1210175

RUN3B
RUN domain-containing protein 3B

1

2

High-throughput

0.437

High

1210181

AMPH
Amphiphysin

1

2

High-throughput

0.437

High

1210195

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.437

High

1210240

Q99JZ4
small monomeric GTPase

1

6

High-throughput

0.437

High

1210266

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.437

High

896018

VATA
V-type proton ATPase catalytic subunit A

1

0

High-throughput

0.426

High

1210200

DMXL2
DmX-like protein 2

1

0

High-throughput

0.426

High

597653

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

9

High-throughput

0.407

High

1210165

TPP2
Tripeptidyl-peptidase 2

1

0

High-throughput

0.279

Low

1210233

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

0

High-throughput

0.279

Low

59246

A2ACC6
Ral GTPase-activating protein subunit beta

1

0

High-throughput

0.249

Low

109316

G5E8N7
Bifunctional polynucleotide phosphatase/kinase

1

0

High-throughput

0.249

Low

204693

IMA3
Importin subunit alpha-3

1

0

High-throughput

0.249

Low

266636

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

0

High-throughput

0.249

Low

398441

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

420095

PRIO
Major prion protein

1

0

High-throughput

0.249

Low

932831

HMCS2
Hydroxymethylglutaryl-CoA synthase, mitochondrial

1

0

High-throughput

0.249

Low

1000552

PYRG1
CTP synthase 1

1

0

High-throughput

0.249

Low

1021830

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.249

Low

1189603

Q3TTC8
Y-box-binding protein 2

1

0

High-throughput

0.249

Low

1189899

F117B
Protein FAM117B

1

0

High-throughput

0.249

Low

1210155

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.249

Low

1210157

S27A1
Long-chain fatty acid transport protein 1

1

0

High-throughput

0.249

Low

1210158

ELAV3
ELAV-like protein 3

1

0

High-throughput

0.249

Low

1210167

KAZRN
Kazrin

1

0

High-throughput

0.249

Low

1210171

TTYH3
Protein tweety homolog 3

1

0

High-throughput

0.249

Low

1210174

ATLA2
Atlastin-2

1

0

High-throughput

0.249

Low

1210177

MIC27
MICOS complex subunit Mic27

1

0

High-throughput

0.249

Low

1210180

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

1210185

FBLL1
RNA 2'-O-methyltransferase FBLL1

1

0

High-throughput

0.249

Low

1210186

C2C2L
Phospholipid transfer protein C2CD2L

1

0

High-throughput

0.249

Low

1210189

Q8BG33
Neurotrimin

1

0

High-throughput

0.249

Low

1210191

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.249

Low

1210194

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.249

Low

1210197

NUP93
Nuclear pore complex protein Nup93

1

0

High-throughput

0.249

Low

1210198

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.249

Low

1210201

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

1210203

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.249

Low

1210206

TENR
Tenascin-R

1

0

High-throughput

0.249

Low

1210213

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.249

Low

1210217

PDLI5
PDZ and LIM domain protein 5

1

0

High-throughput

0.249

Low

1210224

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low

1210227

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.249

Low

1210228

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.249

Low

1210229

BPHL
Serine hydrolase BPHL

1

0

High-throughput

0.249

Low

1210232

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.249

Low

1210237

FACR1
Fatty acyl-CoA reductase 1

1

0

High-throughput

0.249

Low

1210242

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.249

Low

1210245

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

0

High-throughput

0.249

Low

1210246

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.249

Low

1210247

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.249

Low

1210248

MPC2
Mitochondrial pyruvate carrier 2

1

0

High-throughput

0.249

Low

1210249

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.249

Low

1210250

RM28
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

1210251

DPM3
Dolichol-phosphate mannosyltransferase subunit 3

1

0

High-throughput

0.249

Low

1210252

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1210256

SPP
Signal peptide peptidase

1

0

High-throughput

0.249

Low

1210258

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

0

High-throughput

0.249

Low

1210259

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.249

Low

1210261

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.249

Low

1210263

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.249

Low

1210265

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.249

Low

1210270

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.249

Low

1210271

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.249

Low

1210272

GRIA3
Glutamate receptor 3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025