Protein: FKBP3
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8) (FK506-binding nuclear protein) (FKBP-70) (Nucleolar proline isomerase) (Proline rotamase)

Gene: FKBP3, FPR3
Organism: Saccharomyces cerevisiae S288C
Interactions: 188
UniProt ID: P38911

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005527 - macrolide binding
GO:0005730 - nucleolus
GO:0006334 - nucleosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

696326

PP12
Serine/threonine-protein phosphatase PP1-2

5

3

Small-scale

0.919

High

550032

CSK21
Casein kinase II subunit alpha

3

10

Small-scale

0.847

High

757349

FKBP4
FK506-binding protein 4

3

11

High-throughput

0.812

High

366281

HSP82
ATP-dependent molecular chaperone HSP82

4

15

High-throughput

0.776

High

584732

CSK22
Casein kinase II subunit alpha'

2

11

Small-scale

0.755

High

757267

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

13

High-throughput

0.726

High

757371

NOP53
Ribosome biogenesis protein NOP53

5

1

Small-scale

0.702

High

664456

HRR25
Casein kinase I homolog HRR25

1

4

High-throughput

0.691

High

757302

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

9

High-throughput

0.691

High

543720

HSC82
ATP-dependent molecular chaperone HSC82

2

15

High-throughput

0.675

High

757292

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

1

High-throughput

0.670

High

634409

SPB1
27S pre-rRNA

3

2

High-throughput

0.646

High

731810

EBP2
rRNA-processing protein EBP2

3

2

High-throughput

0.646

High

732214

RRP14
Ribosomal RNA-processing protein 14

3

1

High-throughput

0.646

High

757379

DBP10
ATP-dependent RNA helicase DBP10

3

4

High-throughput

0.646

High

757326

NOG1
Nucleolar GTP-binding protein 1

3

5

Small-scale

0.640

High

757331

RRP17
Ribosomal RNA-processing protein 17

3

1

High-throughput

0.640

High

757322

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

10

High-throughput

0.618

High

757329

PKH1
Serine/threonine-protein kinase PKH1

1

11

High-throughput

0.618

High

757365

HRK1
Serine/threonine-protein kinase HRK1

1

6

High-throughput

0.618

High

733823

RPF2
Ribosome biogenesis protein RPF2

2

4

High-throughput

0.611

High

491206

HSP71
Heat shock protein SSA1

4

16

High-throughput

0.608

High

594040

MAK11
Protein MAK11

2

8

Small-scale

0.584

High

757289

RLP7
Ribosome biogenesis protein RLP7

2

3

High-throughput

0.584

High

757308

PESC
Pescadillo homolog

2

3

High-throughput

0.584

High

757313

NOP15
Ribosome biogenesis protein 15

2

5

High-throughput

0.584

High

757330

HAS1
ATP-dependent RNA helicase HAS1

2

9

High-throughput

0.584

High

757357

RLP24
Ribosome biogenesis protein RLP24

2

1

Small-scale

0.584

High

757268

IPL1
Spindle assembly checkpoint kinase

1

11

High-throughput

0.579

High

757361

BRX1
Ribosome biogenesis protein BRX1

2

13

High-throughput

0.576

High

757318

H3
Histone H3

3

7

High-throughput

0.574

High

755285

RPF1
Ribosome production factor 1

2

2

High-throughput

0.571

High

757281

ATAD2
ATPase histone chaperone YTA7

2

6

High-throughput

0.571

High

757335

RRB1
Ribosome assembly protein RRB1

2

4

High-throughput

0.571

High

757367

RRS1
Regulator of ribosome biosynthesis

2

1

High-throughput

0.571

High

757382

H2AZ
Histone H2A.Z

2

7

High-throughput

0.571

High

339627

CDK1
Cyclin-dependent kinase 1

1

6

High-throughput

0.553

High

757378

SMT3
Ubiquitin-like protein SMT3

1

6

High-throughput

0.553

High

757306

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

2

High-throughput

0.536

High

757286

ULP2
Ubiquitin-like-specific protease 2

2

3

High-throughput

0.535

High

471053

RS22A
Small ribosomal subunit protein uS8A

2

3

High-throughput

0.533

High

355481

H2B1
Histone H2B.1

2

4

Small-scale

0.521

High

392428

H2A2
Histone H2A.2

2

3

High-throughput

0.521

High

628040

SIS1
Protein SIS1

2

3

High-throughput

0.521

High

493951

HSP72
Heat shock protein SSA2

2

16

High-throughput

0.504

High

757279

SSB2
Ribosome-associated molecular chaperone SSB2

2

16

High-throughput

0.504

High

511291

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.489

High

757295

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

1

Small-scale

0.489

High

757309

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.489

High

757323

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

High-throughput

0.489

High

757325

ULP1
Ubiquitin-like-specific protease 1

1

3

High-throughput

0.481

High

757364

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.480

High

141328

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

480100

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

501216

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

638749

SPB4
ATP-dependent rRNA helicase SPB4

1

8

High-throughput

0.479

High

645442

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

699681

DRS1
ATP-dependent RNA helicase DRS1

1

6

High-throughput

0.479

High

703051

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.479

High

715439

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.479

High

746239

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

748607

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

754117

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

754858

SSF1
Ribosome biogenesis protein SSF1

1

1

High-throughput

0.479

High

757273

NOC2
Nucleolar complex protein 2

1

3

High-throughput

0.479

High

757275

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

757276

NUG1
Nuclear GTP-binding protein NUG1

1

2

High-throughput

0.479

High

757278

NSA2
Ribosome biogenesis protein NSA2

1

2

High-throughput

0.479

High

757290

NOP2
25S rRNA

1

5

High-throughput

0.479

High

757291

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.479

High

757307

NSA1
Ribosome biogenesis protein NSA1

1

1

High-throughput

0.479

High

757310

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.479

High

757311

NOP13
Nucleolar protein 13

1

1

High-throughput

0.479

High

757328

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

757334

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

757339

PUF6
Pumilio homology domain family member 6

1

3

High-throughput

0.479

High

757342

ERB1
Ribosome biogenesis protein ERB1

1

9

High-throughput

0.479

High

757344

RRP5
rRNA biogenesis protein RRP5

1

5

High-throughput

0.479

High

757347

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

757350

JIP5
WD repeat-containing protein JIP5

1

4

High-throughput

0.479

High

757352

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

757353

NOC4
Nucleolar complex protein 4

1

6

High-throughput

0.479

High

757356

NOC3
Nucleolar complex-associated protein 3

1

4

High-throughput

0.479

High

757360

NOP12
Nucleolar protein 12

1

5

High-throughput

0.479

High

757368

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

757369

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.479

High

757370

YTM1
Ribosome biogenesis protein YTM1

1

11

High-throughput

0.479

High

757375

MAK21
Ribosome biogenesis protein MAK21

1

6

High-throughput

0.479

High

757381

IF6
Eukaryotic translation initiation factor 6

1

3

High-throughput

0.479

High

710882

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

625973

PTP1
Tyrosine-protein phosphatase 1

1

2

Small-scale

0.457

High

356474

H4
Histone H4

1

5

High-throughput

0.445

High

416304

SIR3
Regulatory protein SIR3

1

2

High-throughput

0.445

High

501367

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

1

Small-scale

0.445

High

610979

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

1

High-throughput

0.445

High

757277

UTP7
U3 small nucleolar RNA-associated protein 7

1

6

High-throughput

0.445

High

757294

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.445

High

757299

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

3

High-throughput

0.445

High

757300

NET1
Nucleolar protein NET1

1

1

High-throughput

0.445

High

757301

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.445

High

757320

SEN1
Helicase SEN1

1

3

Small-scale

0.445

High

757355

RIX7
Ribosome biogenesis ATPase RIX7

1

4

High-throughput

0.445

High

355892

H2B2
Histone H2B.2

1

4

High-throughput

0.437

High

383142

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

402947

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

2

Small-scale

0.437

High

405619

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

407046

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.437

High

425949

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

480669

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

482261

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

558051

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

604554

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

4

High-throughput

0.437

High

645030

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

662205

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

663863

TF3B
Transcription factor IIIB 70 kDa subunit

1

5

High-throughput

0.437

High

688239

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.437

High

706269

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

742790

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.437

High

752452

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

757271

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.437

High

757272

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

757284

MLP2
Protein MLP2

1

5

High-throughput

0.437

High

757303

MOG1
Nuclear import protein MOG1

1

3

High-throughput

0.437

High

757305

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

3

High-throughput

0.437

High

757314

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.437

High

757315

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

757317

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.437

High

757319

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

757324

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.437

High

757345

HRQ1
ATP-dependent helicase HRQ1

1

2

Small-scale

0.437

High

757348

YL455
PWWP domain-containing protein YLR455W

1

2

High-throughput

0.437

High

757351

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

757354

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

757362

SGO1
Shugoshin

1

1

High-throughput

0.437

High

757366

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

757373

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.437

High

757383

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.437

High

609085

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

757283

PTPA1
Serine/threonine-protein phosphatase 2A activator 1

1

0

High-throughput

0.426

High

757293

ECO1
N-acetyltransferase ECO1

1

0

High-throughput

0.426

High

757332

DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.426

High

757338

BUD22
Bud site selection protein 22

1

0

High-throughput

0.426

High

757358

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

757312

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.417

High

605348

HSP74
Heat shock protein SSA4

1

16

High-throughput

0.407

High

633219

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.407

High

636620

CDC48
Cell division control protein 48

1

4

Small-scale

0.407

High

650291

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.407

High

694690

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.407

High

705170

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.407

High

733247

SET3
SET domain-containing protein 3

1

2

High-throughput

0.407

High

741333

STT4
Phosphatidylinositol 4-kinase STT4

1

4

High-throughput

0.407

High

756160

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

1

High-throughput

0.407

High

757280

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

Small-scale

0.407

High

757296

STU2
Protein STU2

1

1

High-throughput

0.407

High

757297

YPP1
Cargo-transport protein YPP1

1

1

High-throughput

0.407

High

757304

HLJ1
Protein HLJ1

1

4

High-throughput

0.407

High

757316

HDA1
Histone deacetylase HDA1

1

3

High-throughput

0.407

High

757327

HOS3
Histone deacetylase HOS3

1

4

High-throughput

0.407

High

757343

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.407

High

757359

BUD20
Bud site selection protein 20

1

1

High-throughput

0.407

High

757376

RLM1
Transcription factor RLM1

1

1

High-throughput

0.407

High

757282

PPAL
Low molecular weight phosphotyrosine protein phosphatase

1

0

Small-scale

0.301

High

757287

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

0

High-throughput

0.279

Low

757321

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

0

High-throughput

0.279

Low

757333

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

757346

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.279

Low

757363

DIA2
Protein DIA2

1

0

High-throughput

0.279

Low

472189

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

605029

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.249

Low

664818

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

699068

VATL2
V-type proton ATPase subunit c'

1

0

High-throughput

0.249

Low

700403

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

757274

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.249

Low

757285

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

757288

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

757372

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

757374

YRA1
RNA annealing protein YRA1

1

0

Small-scale

0.249

Low

757380

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.249

Low

757269

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

757270

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

757298

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

757336

UBX2
UBX domain-containing protein 2

1

0

Small-scale

0.232

Low

757337

SEG1
Eisosome protein SEG1

1

0

High-throughput

0.232

Low

757340

HSP31
Glutathione-independent glyoxalase HSP31

1

0

High-throughput

0.232

Low

757341

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.232

Low

757377

YO093
Uncharacterized protein YOR093C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024