Protein: FBX32
F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)

Gene: FBX32, Fbxo32
Organism: Mus musculus
Interactions: 153
UniProt ID: Q9CPU7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0014894 - response to denervation involved in regulation of muscle adaptation
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518526

MYOD1
Myoblast determination protein 1

4

3

Small-scale

0.692

High

1298427

UB2R1
Ubiquitin-conjugating enzyme E2 R1

2

2

Small-scale

0.602

High

1423580

SKP1
S-phase kinase-associated protein 1

2

3

Small-scale

0.584

High

1423581

CUL1
Cullin-1

2

4

Small-scale

0.584

High

1423582

IKBA
NF-kappa-B inhibitor alpha

1

1

Small-scale

0.561

High

558943

MYOG
Myogenin

1

3

Small-scale

0.554

High

1354148

MYCD
Myocardin

1

0

Small-scale

0.537

High

1423573

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

2

Small-scale

0.533

High

312622

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.479

High

312786

PRS6A
26S proteasome regulatory subunit 6A

1

5

High-throughput

0.479

High

373707

MYC
Myc proto-oncogene protein

1

1

Small-scale

0.479

High

421238

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.479

High

439047

LDHA
L-lactate dehydrogenase A chain

1

1

High-throughput

0.479

High

456925

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

462145

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

518556

ANXA1
Annexin A1

1

1

High-throughput

0.479

High

518698

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

602938

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

616484

COF1
Cofilin-1

1

3

High-throughput

0.479

High

628520

VIME
Vimentin

1

4

High-throughput

0.479

High

638874

ENOB
Beta-enolase

1

2

High-throughput

0.479

High

665769

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

688205

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

High-throughput

0.479

High

723766

DESM
Desmin

1

6

High-throughput

0.479

High

839131

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.479

High

881014

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

945981

EF2
Elongation factor 2

1

1

High-throughput

0.479

High

949836

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.479

High

953285

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.479

High

966079

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.479

High

967124

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

2

High-throughput

0.479

High

969115

PRS8
26S proteasome regulatory subunit 8

1

3

High-throughput

0.479

High

987314

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

High-throughput

0.479

High

989278

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

989461

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

990046

1433Z
14-3-3 protein zeta/delta

1

2

High-throughput

0.479

High

993112

ACTG
Actin, cytoplasmic 2

1

6

High-throughput

0.479

High

997268

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.479

High

1021201

PKP1
Plakophilin-1

1

2

High-throughput

0.479

High

1036162

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

1037845

MYH6
Myosin-6

1

7

High-throughput

0.479

High

1042174

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

1223332

K1C14
Keratin, type I cytoskeletal 14

1

1

High-throughput

0.479

High

1253429

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.479

High

1253450

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

2

High-throughput

0.479

High

1297234

Q8BQ46
TAF15 RNA polymerase II, TATA box binding protein

1

1

High-throughput

0.479

High

1408881

SYK
Lysine--tRNA ligase

1

1

High-throughput

0.479

High

1423564

1433B
14-3-3 protein beta/alpha

1

2

High-throughput

0.479

High

1423568

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

3

High-throughput

0.479

High

1423569

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

3

High-throughput

0.479

High

1423574

SYNCI
Syncoilin

1

6

High-throughput

0.479

High

1423575

LDB3
LIM domain-binding protein 3

1

1

High-throughput

0.479

High

1423577

UBQL2
Ubiquilin-2

1

4

High-throughput

0.479

High

59165

PRD16
Histone-lysine N-methyltransferase PRDM16

1

0

High-throughput

0.458

High

109295

G5E8K8
AHNAK nucleoprotein

1

0

High-throughput

0.458

High

204628

PURB
Transcriptional regulator protein Pur-beta

1

0

High-throughput

0.458

High

236351

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

266718

PGAM2
Phosphoglycerate mutase 2

1

0

High-throughput

0.458

High

267292

RTN2
Reticulon-2

1

0

High-throughput

0.458

High

467769

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

570752

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

576869

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

590778

CAH3
Carbonic anhydrase 3

1

0

High-throughput

0.458

High

598679

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.458

High

746082

PRVA
Parvalbumin alpha

1

0

High-throughput

0.458

High

778152

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

852101

ALDR
Aldo-keto reductase family 1 member B1

1

0

High-throughput

0.458

High

868421

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

912310

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

949484

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.458

High

954058

IF4A1
Eukaryotic initiation factor 4A-I

1

0

High-throughput

0.458

High

973674

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

984688

CYC
Cytochrome c, somatic

1

0

High-throughput

0.458

High

995526

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

1021219

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.458

High

1023504

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.458

High

1033497

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1221577

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

1224097

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

1243802

ARMD3
Armadillo-like helical domain-containing protein 3

1

0

High-throughput

0.458

High

1295951

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.458

High

1296862

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.458

High

1298038

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.458

High

1298563

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

High-throughput

0.458

High

1341501

H2AJ
Histone H2A.J

1

0

High-throughput

0.458

High

1408995

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

1423565

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

1423567

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

1423572

TELO2
Telomere length regulation protein TEL2 homolog

1

0

High-throughput

0.458

High

1423576

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

High-throughput

0.458

High

1423584

HDAC6
Protein deacetylase HDAC6

1

0

Small-scale

0.458

High

67316

A6ZI47
Fructose-bisphosphate aldolase

1

2

High-throughput

0.437

High

98076

DESP
Desmoplakin

1

6

High-throughput

0.437

High

312557

CSN4
COP9 signalosome complex subunit 4

1

2

High-throughput

0.437

High

380798

HBB1
Hemoglobin subunit beta-1

1

2

High-throughput

0.437

High

380804

HBB2
Hemoglobin subunit beta-2

1

2

High-throughput

0.437

High

403104

K2C1
Keratin, type II cytoskeletal 1

1

3

High-throughput

0.437

High

421213

ALDOC
Fructose-bisphosphate aldolase C

1

2

High-throughput

0.437

High

437615

MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

2

High-throughput

0.437

High

459397

ALBU
Albumin

1

1

High-throughput

0.437

High

469628

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

563087

MYH3
Myosin-3

1

7

High-throughput

0.437

High

563090

MYH8
Myosin-8

1

7

High-throughput

0.437

High

801652

HSPA9
Stress-70 protein, mitochondrial

1

5

High-throughput

0.437

High

940854

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

1

3

High-throughput

0.437

High

996582

ACTS
Actin, alpha skeletal muscle

1

5

High-throughput

0.437

High

1000369

MYBPH
Myosin-binding protein H

1

2

High-throughput

0.437

High

1009930

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.437

High

1009946

TCPB
T-complex protein 1 subunit beta

1

4

High-throughput

0.437

High

1021467

MYL11
Myosin regulatory light chain 11

1

2

High-throughput

0.437

High

1197943

LRC47
Leucine-rich repeat-containing protein 47

1

1

High-throughput

0.437

High

1211235

MYH4
Myosin-4

1

7

High-throughput

0.437

High

1211238

MYH1
Myosin-1

1

8

High-throughput

0.437

High

1221211

MYL6
Myosin light polypeptide 6

1

2

High-throughput

0.437

High

1234249

Q6IFZ8
Predicted gene 5414

1

3

High-throughput

0.437

High

1261009

Q792Z0
trypsin

1

1

High-throughput

0.437

High

1274142

ASAP2
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

1

1

High-throughput

0.437

High

1274513

SRCA
Sarcalumenin

1

1

High-throughput

0.437

High

1295884

ACTBL
Beta-actin-like protein 2

1

6

High-throughput

0.437

High

1296699

Q8BIS2
IF rod domain-containing protein

1

3

High-throughput

0.437

High

1296831

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

1298717

MYL6B
Myosin light chain 6B

1

2

High-throughput

0.437

High

1317158

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.437

High

1353976

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.437

High

1362195

Q91VB8
Alpha globin 1

1

2

High-throughput

0.437

High

1362362

SIG12
Sialic acid-binding Ig-like lectin 12

1

1

High-throughput

0.437

High

1362917

TBB6
Tubulin beta-6 chain

1

8

High-throughput

0.437

High

1423566

TBB2B
Tubulin beta-2B chain

1

8

High-throughput

0.437

High

1423578

AFAD
Afadin

1

1

High-throughput

0.437

High

1423583

Q9Z1R9
trypsin

1

1

High-throughput

0.437

High

148331

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

266732

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.249

Low

312801

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

456043

KCRM
Creatine kinase M-type

1

0

High-throughput

0.249

Low

536210

CO1A1
Collagen alpha-1(I) chain

1

0

High-throughput

0.249

Low

609262

LYZ1
Lysozyme C-1

1

0

High-throughput

0.249

Low

635057

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.249

Low

693439

MAP4
Microtubule-associated protein 4

1

0

High-throughput

0.249

Low

791895

FBLN2
Fibulin-2

1

0

High-throughput

0.249

Low

946700

TPM1
Tropomyosin alpha-1 chain

1

0

High-throughput

0.249

Low

981232

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

1048819

CO6A1

1

0

High-throughput

0.249

Low

1070190

INF2
Inverted formin-2

1

0

High-throughput

0.249

Low

1191027

Q3UZL8
Signal recognition particle subunit SRP72

1

0

High-throughput

0.249

Low

1200633

Q542V3
Serine and arginine-rich splicing factor 4

1

0

High-throughput

0.249

Low

1225832

VINC
Vinculin

1

0

High-throughput

0.249

Low

1282897

UBP2L
Ubiquitin-associated protein 2-like

1

0

High-throughput

0.249

Low

1297991

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.249

Low

1362937

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.249

Low

1408928

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.249

Low

1423570

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.249

Low

1423571

EF1G
Elongation factor 1-gamma

1

0

High-throughput

0.249

Low

1423579

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025