Protein: IF2P
Eukaryotic translation initiation factor 5B (eIF-5B) (EC 3.6.5.3) (Translation initiation factor IF-2)

Gene: IF2P, FUN12
Organism: Saccharomyces cerevisiae S288C
Interactions: 224
UniProt ID: P39730

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0001732 - formation of cytoplasmic translation initiation complex
GO:0003743 - translation initiation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757386

IF1A
Eukaryotic translation initiation factor 1A

5

6

Small-scale

0.936

High

750126

IF5
Eukaryotic translation initiation factor 5

3

4

High-throughput

0.855

High

399477

RLA0
Large ribosomal subunit protein uL10

2

2

High-throughput

0.789

High

690931

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

2

14

Small-scale

0.776

High

447190

IF2B
Eukaryotic translation initiation factor 2 subunit beta

2

4

Small-scale

0.754

High

410127

EIF3B
Eukaryotic translation initiation factor 3 subunit B

6

3

Small-scale

0.730

High

691547

EIF3C
Eukaryotic translation initiation factor 3 subunit C

4

1

Small-scale

0.691

High

450441

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

3

4

High-throughput

0.662

High

763847

ARB1
ABC transporter ATP-binding protein ARB1

3

8

Small-scale

0.662

High

763900

EIF3G
Eukaryotic translation initiation factor 3 subunit G

3

6

Small-scale

0.656

High

481340

RL2A
Large ribosomal subunit protein uL2A

3

4

High-throughput

0.640

High

746988

EIF3A
Eukaryotic translation initiation factor 3 subunit A

3

8

Small-scale

0.640

High

543772

HSC82
ATP-dependent molecular chaperone HSC82

3

9

High-throughput

0.633

High

704342

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

1

High-throughput

0.628

High

404845

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.618

High

593853

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

5

Small-scale

0.618

High

704172

DOM34
Protein DOM34

1

2

High-throughput

0.618

High

763801

RBG1
Ribosome-interacting GTPase 1

1

9

High-throughput

0.618

High

763876

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.618

High

404593

RL7A
Large ribosomal subunit protein uL30A

2

4

High-throughput

0.611

High

406137

RL36A
Large ribosomal subunit protein eL36A

2

2

High-throughput

0.611

High

407065

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.611

High

471068

RS22A
Small ribosomal subunit protein uS8A

2

3

High-throughput

0.611

High

534771

RL30
Large ribosomal subunit protein eL30

2

1

High-throughput

0.611

High

534997

RL3
Large ribosomal subunit protein uL3

2

1

High-throughput

0.611

High

564294

RL8A
Large ribosomal subunit protein eL8A

2

6

High-throughput

0.611

High

667186

RL8B
Large ribosomal subunit protein eL8B

2

6

High-throughput

0.611

High

763850

RL13B
Large ribosomal subunit protein eL13B

2

2

High-throughput

0.611

High

763858

RL10
Large ribosomal subunit protein uL16

2

1

High-throughput

0.611

High

763929

RL13A
Large ribosomal subunit protein eL13A

2

2

High-throughput

0.611

High

763887

MCE1
mRNA-capping enzyme subunit alpha

2

0

High-throughput

0.595

High

141345

RS9A
Small ribosomal subunit protein uS4A

2

2

High-throughput

0.584

High

383160

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.584

High

405634

RL26A
Large ribosomal subunit protein uL24A

2

2

High-throughput

0.584

High

472202

RL31A
Large ribosomal subunit protein eL31A

2

2

High-throughput

0.584

High

478901

RL20B
Large ribosomal subunit protein eL20B

2

1

High-throughput

0.584

High

479747

RS4A
Small ribosomal subunit protein eS4A

2

1

High-throughput

0.584

High

481921

RL12B
Large ribosomal subunit protein uL11B

2

1

High-throughput

0.584

High

628080

SIS1
Protein SIS1

2

14

High-throughput

0.584

High

645037

RL16A
Large ribosomal subunit protein uL13A

2

7

High-throughput

0.584

High

763845

IF4F1
Eukaryotic initiation factor 4F subunit p150

2

4

Small-scale

0.584

High

763846

IF4F2
Eukaryotic initiation factor 4F subunit p130

2

4

Small-scale

0.584

High

763860

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

6

High-throughput

0.584

High

763889

RS15
Small ribosomal subunit protein uS19

2

1

Small-scale

0.584

High

368085

EF1A
Elongation factor 1-alpha

1

6

High-throughput

0.575

High

498938

RL4A
Large ribosomal subunit protein uL4A

2

2

High-throughput

0.571

High

763872

RL4B
Large ribosomal subunit protein uL4B

2

2

High-throughput

0.571

High

763883

JJJ1
J protein JJJ1

2

11

High-throughput

0.571

High

763925

RIO1
Serine/threonine-protein kinase RIO1

2

2

High-throughput

0.571

High

549399

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

2

High-throughput

0.567

High

763880

GATF
Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial

2

0

High-throughput

0.563

High

399755

RLA1
Large ribosomal subunit protein P1A

2

2

Small-scale

0.558

High

491291

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.552

High

511390

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.552

High

763849

SSB2
Ribosome-associated molecular chaperone SSB2

2

9

High-throughput

0.552

High

704030

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

1

High-throughput

0.541

High

356486

H4
Histone H4

2

1

High-throughput

0.537

High

644895

RS5
Small ribosomal subunit protein uS7

1

7

High-throughput

0.536

High

676067

XPO1
Exportin-1

1

2

High-throughput

0.536

High

752366

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

6

High-throughput

0.536

High

763855

SGN1
RNA-binding protein SGN1

1

3

High-throughput

0.536

High

763874

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

6

High-throughput

0.536

High

763882

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

763888

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

763932

RS22B
Small ribosomal subunit protein uS8B

1

3

High-throughput

0.536

High

425344

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

604297

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

763910

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.513

High

763864

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.493

High

763903

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.489

High

763904

RRP5
rRNA biogenesis protein RRP5

1

10

High-throughput

0.489

High

763933

AP2M
AP-2 complex subunit mu

1

7

Small-scale

0.481

High

145736

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.479

High

339647

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.479

High

357504

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.479

High

358076

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

366323

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

382750

RL24A
Large ribosomal subunit protein eL24A

1

2

High-throughput

0.479

High

405016

RL6B
Large ribosomal subunit protein eL6B

1

2

High-throughput

0.479

High

405196

RL17A
Large ribosomal subunit protein uL22A

1

4

High-throughput

0.479

High

406003

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

406345

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.479

High

406538

RL22A
Large ribosomal subunit protein eL22A

1

3

High-throughput

0.479

High

407527

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.479

High

407930

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

408366

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

10

High-throughput

0.479

High

410386

SC160
Protein SCP160

1

4

High-throughput

0.479

High

413515

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425963

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

471781

RL27A
Large ribosomal subunit protein eL27A

1

2

High-throughput

0.479

High

471900

RL27B
Large ribosomal subunit protein eL27B

1

2

High-throughput

0.479

High

472505

RL31B
Large ribosomal subunit protein eL31B

1

2

High-throughput

0.479

High

480115

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

480683

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

481643

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.479

High

482272

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

482723

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.479

High

482875

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

558063

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

560977

EF3A
Elongation factor 3A

1

7

High-throughput

0.479

High

621473

RL24B
Large ribosomal subunit protein eL24B

1

2

High-throughput

0.479

High

624096

DBP2
ATP-dependent RNA helicase DBP2

1

3

High-throughput

0.479

High

631891

RS2
Small ribosomal subunit protein uS5

1

9

High-throughput

0.479

High

640956

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

645215

RL16B
Large ribosomal subunit protein uL13B

1

7

High-throughput

0.479

High

645458

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

662286

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

664839

BMH1
Protein BMH1

1

3

High-throughput

0.479

High

680725

HS104
Heat shock protein 104

1

18

High-throughput

0.479

High

698812

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

700422

RSSA1
Small ribosomal subunit protein uS2A

1

8

High-throughput

0.479

High

701439

SC61A
Protein transport protein SEC61

1

2

High-throughput

0.479

High

706284

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

729923

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

732725

RL14A
Large ribosomal subunit protein eL14A

1

2

High-throughput

0.479

High

741230

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

3

High-throughput

0.479

High

742808

GBLP
Small ribosomal subunit protein RACK1

1

6

High-throughput

0.479

High

743264

RL32
Large ribosomal subunit protein eL32

1

2

High-throughput

0.479

High

752036

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.479

High

752468

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

753665

RL14B
Large ribosomal subunit protein eL14B

1

2

High-throughput

0.479

High

761939

DHH1
ATP-dependent RNA helicase DHH1

1

8

High-throughput

0.479

High

762212

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

763851

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

6

High-throughput

0.479

High

763854

RL34B
Large ribosomal subunit protein eL34B

1

2

High-throughput

0.479

High

763857

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.479

High

763859

ELP2
Elongator complex protein 2

1

5

High-throughput

0.479

High

763862

RSSA2
Small ribosomal subunit protein uS2B

1

8

High-throughput

0.479

High

763863

RL17B
Large ribosomal subunit protein uL22B

1

4

High-throughput

0.479

High

763866

RS7B
Small ribosomal subunit protein eS7B

1

2

High-throughput

0.479

High

763868

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

763870

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

763871

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.479

High

763877

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

763878

RL26B
Large ribosomal subunit protein uL24B

1

2

High-throughput

0.479

High

763879

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.479

High

763881

TR112
Multifunctional methyltransferase subunit TRM112

1

1

Small-scale

0.479

High

763884

FAP1
FKBP12-associated protein 1

1

2

High-throughput

0.479

High

763885

RL22B
Large ribosomal subunit protein eL22B

1

3

High-throughput

0.479

High

763886

RL34A
Large ribosomal subunit protein eL34A

1

2

High-throughput

0.479

High

763890

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.479

High

763891

ABF2
ARS-binding factor 2, mitochondrial

1

7

High-throughput

0.479

High

763892

RL21A
Large ribosomal subunit protein eL21A

1

2

High-throughput

0.479

High

763893

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

763895

ELP3
Elongator complex protein 3

1

1

High-throughput

0.479

High

763896

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

763897

CLU
Clustered mitochondria protein 1

1

2

High-throughput

0.479

High

763898

HMO1
High mobility group protein 1

1

6

High-throughput

0.479

High

763899

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

763901

DHR1
Probable ATP-dependent RNA helicase DHR1

1

9

High-throughput

0.479

High

763908

LCB5
Sphingoid long chain base kinase 5

1

1

High-throughput

0.479

High

763913

ELP1
Elongator complex protein 1

1

1

High-throughput

0.479

High

763914

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

763915

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

1

Small-scale

0.479

High

763917

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

763919

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

763922

CHS5
Chitin biosynthesis protein CHS5

1

1

High-throughput

0.479

High

763928

RL21B
Large ribosomal subunit protein eL21B

1

2

High-throughput

0.479

High

763930

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.479

High

763931

RS25A
Small ribosomal subunit protein eS25A

1

1

High-throughput

0.479

High

733130

DBP7
ATP-dependent RNA helicase DBP7

1

8

High-throughput

0.470

High

763924

MAK21
Ribosome biogenesis protein MAK21

1

1

High-throughput

0.470

High

387905

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.458

High

406223

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

479116

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

482979

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

519520

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

524314

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

624269

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.458

High

733659

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

747344

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

748137

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

756162

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

High-throughput

0.458

High

756925

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

759349

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

763563

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

763853

TM108
Protein TMA108

1

0

High-throughput

0.458

High

763875

PSP2
Protein PSP2

1

0

High-throughput

0.458

High

763894

ELP4
Elongator complex protein 4

1

0

High-throughput

0.458

High

763905

RQC1
Ribosome quality control complex subunit 1

1

0

High-throughput

0.458

High

763907

EFM7
Protein N-terminal and lysine N-methyltransferase EFM7

1

0

High-throughput

0.458

High

763916

SGO1
Shugoshin

1

0

High-throughput

0.458

High

763921

AEP3
ATPase expression protein 3

1

0

Small-scale

0.458

High

763927

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.458

High

761119

PCF11
Protein PCF11

1

1

High-throughput

0.457

High

360887

TBB
Tubulin beta chain

1

4

High-throughput

0.445

High

478217

HSP77
Import motor subunit, mitochondrial

1

11

High-throughput

0.445

High

494023

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

605042

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.445

High

633241

MAS5
Mitochondrial protein import protein MAS5

1

12

High-throughput

0.445

High

694741

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

705202

HSP78
Heat shock protein 78, mitochondrial

1

13

High-throughput

0.445

High

754429

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

761230

CAJ1
Protein CAJ1

1

19

High-throughput

0.445

High

763873

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

6

High-throughput

0.445

High

763926

RL7B
Large ribosomal subunit protein uL30B

1

4

High-throughput

0.445

High

514559

BIK1
Nuclear fusion protein BIK1

1

1

High-throughput

0.439

High

496050

RLA3
Large ribosomal subunit protein P1B

1

2

High-throughput

0.437

High

532782

ACOX
Acyl-coenzyme A oxidase

1

4

High-throughput

0.437

High

634611

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.437

High

638759

SPB4
ATP-dependent rRNA helicase SPB4

1

8

High-throughput

0.437

High

730806

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

745665

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

751025

RCK1
Serine/threonine-protein kinase RCK1

1

2

High-throughput

0.437

High

754119

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.437

High

763906

HRQ1
ATP-dependent helicase HRQ1

1

9

Small-scale

0.437

High

763918

AP3D
AP-3 complex subunit delta

1

8

High-throughput

0.437

High

763923

YRA1
RNA annealing protein YRA1

1

3

High-throughput

0.437

High

763861

ERJ5
ER-localized J domain-containing protein 5

1

15

High-throughput

0.407

High

763867

HLJ1
Protein HLJ1

1

14

High-throughput

0.407

High

763902

PUF6
Pumilio homology domain family member 6

3

0

Small-scale

0.353

High

698263

CDC13
Cell division control protein 13

1

0

Small-scale

0.265

Low

763920

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.251

Low

600302

DAL82
Protein DAL82

1

0

High-throughput

0.249

Low

688085

SRP21
Signal recognition particle subunit SRP21

1

0

High-throughput

0.249

Low

763848

THO1
Protein THO1

1

0

High-throughput

0.249

Low

763852

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.249

Low

763856

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

763865

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

763869

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

763909

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.249

Low

763911

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

763934

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

763912

CSC1
Calcium permeable stress-gated cation channel 1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024