Protein: NOC2
Nucleolar complex protein 2

Gene: NOC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 200
UniProt ID: P39744

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

764274

MAK21
Ribosome biogenesis protein MAK21

17

6

Small-scale

0.764

High

764257

NOC3
Nucleolar complex-associated protein 3

11

2

Small-scale

0.757

High

764242

RRP5
rRNA biogenesis protein RRP5

11

1

Small-scale

0.755

High

742016

NOP4
Nucleolar protein 4

8

1

Small-scale

0.753

High

764240

ERB1
Ribosome biogenesis protein ERB1

7

1

Small-scale

0.750

High

764186

NUG1
Nuclear GTP-binding protein NUG1

9

1

Small-scale

0.748

High

764208

PESC
Pescadillo homolog

9

1

Small-scale

0.747

High

764193

NOP2
25S rRNA

7

2

Small-scale

0.745

High

764192

RLP7
Ribosome biogenesis protein RLP7

7

2

Small-scale

0.741

High

764233

HAS1
ATP-dependent RNA helicase HAS1

7

3

Small-scale

0.741

High

638760

SPB4
ATP-dependent rRNA helicase SPB4

7

3

Small-scale

0.740

High

754860

SSF1
Ribosome biogenesis protein SSF1

7

1

Small-scale

0.739

High

764276

DBP10
ATP-dependent RNA helicase DBP10

6

1

High-throughput

0.735

High

764270

YTM1
Ribosome biogenesis protein YTM1

6

1

Small-scale

0.726

High

764218

NOP15
Ribosome biogenesis protein 15

6

3

Small-scale

0.726

High

715444

RRP1
Ribosomal RNA-processing protein 1

6

1

Small-scale

0.723

High

733827

RPF2
Ribosome biogenesis protein RPF2

9

0

Small-scale

0.720

High

764196

LOC1
60S ribosomal subunit assembly/export protein LOC1

7

0

Small-scale

0.718

High

764187

NSA2
Ribosome biogenesis protein NSA2

7

0

Small-scale

0.712

High

764259

NOP12
Nucleolar protein 12

5

2

Small-scale

0.711

High

764260

BRX1
Ribosome biogenesis protein BRX1

5

4

Small-scale

0.707

High

634411

SPB1
27S pre-rRNA

5

1

Small-scale

0.704

High

699684

DRS1
ATP-dependent RNA helicase DRS1

5

2

Small-scale

0.704

High

754120

CIC1
Proteasome-interacting protein CIC1

6

0

Small-scale

0.699

High

764205

NSA1
Ribosome biogenesis protein NSA1

6

0

Small-scale

0.695

High

764232

NOG1
Nucleolar GTP-binding protein 1

6

0

Small-scale

0.695

High

755287

RPF1
Ribosome production factor 1

6

0

High-throughput

0.695

High

703054

MRT4
Ribosome assembly factor MRT4

4

2

Small-scale

0.686

High

731814

EBP2
rRNA-processing protein EBP2

5

0

Small-scale

0.681

High

501218

MAK16
Protein MAK16

4

1

Small-scale

0.680

High

744193

MAK5
ATP-dependent RNA helicase MAK5

4

3

Small-scale

0.680

High

764267

RRS1
Regulator of ribosome biosynthesis

5

0

Small-scale

0.678

High

764258

RLP24
Ribosome biogenesis protein RLP24

4

1

Small-scale

0.676

High

764246

FKBP4
FK506-binding protein 4

3

3

High-throughput

0.669

High

597841

PWP1
Periodic tryptophan protein 1

3

2

High-throughput

0.666

High

764279

IF6
Eukaryotic translation initiation factor 6

4

0

Small-scale

0.657

High

732216

RRP14
Ribosomal RNA-processing protein 14

4

0

Small-scale

0.651

High

549401

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

1

High-throughput

0.650

High

733131

DBP7
ATP-dependent RNA helicase DBP7

3

3

High-throughput

0.650

High

481029

RL23B
Large ribosomal subunit protein uL14B

4

0

Small-scale

0.648

High

764185

NOP16
Nucleolar protein 16

4

0

Small-scale

0.648

High

764183

NOC2
Nucleolar complex protein 2

3

1

High-throughput

0.646

High

691376

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

3

2

High-throughput

0.643

High

640958

RL5
Large ribosomal subunit protein uL18

3

0

Small-scale

0.628

High

764207

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.622

High

764262

NOP8
60S ribosome subunit biogenesis protein NOP8

3

0

High-throughput

0.618

High

764271

NOP53
Ribosome biogenesis protein NOP53

3

0

High-throughput

0.618

High

564295

RL8A
Large ribosomal subunit protein eL8A

4

2

Small-scale

0.617

High

764216

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

2

2

High-throughput

0.614

High

764235

RRP17
Ribosomal RNA-processing protein 17

3

0

High-throughput

0.613

High

764237

PUF6
Pumilio homology domain family member 6

3

0

Small-scale

0.613

High

764261

REXO4
RNA exonuclease 4

3

0

High-throughput

0.613

High

645038

RL16A
Large ribosomal subunit protein uL13A

2

2

Small-scale

0.611

High

764256

RIX7
Ribosome biogenesis ATPase RIX7

2

1

Small-scale

0.611

High

534998

RL3
Large ribosomal subunit protein uL3

3

1

Small-scale

0.599

High

764215

NOG2
Nucleolar GTP-binding protein 2

2

1

High-throughput

0.594

High

764211

H1
Histone H1

2

0

High-throughput

0.587

High

764217

NOP13
Nucleolar protein 13

2

0

Small-scale

0.585

High

405197

RL17A
Large ribosomal subunit protein uL22A

2

1

Small-scale

0.584

High

405637

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.584

High

594043

MAK11
Protein MAK11

2

1

Small-scale

0.584

High

764210

YG5X
Putative methyltransferase YGR283C

2

1

High-throughput

0.584

High

764239

UTP14
U3 small nucleolar RNA-associated protein 14

2

1

High-throughput

0.584

High

764241

YM91
Putative methyltransferase YMR310C

2

1

High-throughput

0.584

High

764248

DBP9
ATP-dependent RNA helicase DBP9

2

2

High-throughput

0.584

High

764272

SSF2
Ribosome biogenesis protein SSF2

2

1

High-throughput

0.584

High

764277

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

764236

DHR1
Probable ATP-dependent RNA helicase DHR1

2

0

High-throughput

0.576

High

543777

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

383163

RL25
Large ribosomal subunit protein uL23

2

0

Small-scale

0.559

High

634612

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

710885

URB1
Nucleolar pre-ribosomal-associated protein 1

2

0

Small-scale

0.559

High

748612

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

764195

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

764199

URB2
Nucleolar pre-ribosomal-associated protein 2

2

0

High-throughput

0.559

High

764251

RRP15
Ribosomal RNA-processing protein 15

2

0

High-throughput

0.559

High

764268

NIP7
60S ribosome subunit biogenesis protein NIP7

2

0

Small-scale

0.559

High

494028

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

511396

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

704343

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

High-throughput

0.547

High

404594

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.536

High

676070

XPO1
Exportin-1

1

1

High-throughput

0.536

High

764202

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.536

High

764226

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

478902

RL20B
Large ribosomal subunit protein eL20B

2

1

Small-scale

0.533

High

399479

RLA0
Large ribosomal subunit protein uL10

2

2

Small-scale

0.521

High

624097

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.518

High

655845

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.518

High

764204

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.515

High

764273

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.515

High

764200

YMR1
Phosphoinositide 3-phosphatase

1

0

High-throughput

0.513

High

764214

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

764255

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

571897

SKI3
Superkiller protein 3

1

0

High-throughput

0.493

High

697641

FADH
S-(hydroxymethyl)glutathione dehydrogenase

1

0

High-throughput

0.493

High

759350

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

764245

YL455
PWWP domain-containing protein YLR455W

1

0

High-throughput

0.493

High

382751

RL24A
Large ribosomal subunit protein eL24A

1

1

Small-scale

0.479

High

392437

H2A2
Histone H2A.2

1

3

High-throughput

0.479

High

407934

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

413518

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

471400

RL11A
Large ribosomal subunit protein uL5A

1

1

Small-scale

0.479

High

480116

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

482876

RL35A
Large ribosomal subunit protein uL29A

1

1

High-throughput

0.479

High

498939

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.479

High

645216

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

662289

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

757273

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.479

High

764189

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

764197

MTR4
ATP-dependent RNA helicase DOB1

1

1

Small-scale

0.479

High

764213

DBP6
ATP-dependent RNA helicase DBP6

1

3

High-throughput

0.479

High

764219

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

764220

RCM1
25S rRNA

1

2

High-throughput

0.479

High

764221

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

764222

H3
Histone H3

1

4

High-throughput

0.479

High

764224

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

764243

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

764247

JIP5
WD repeat-containing protein JIP5

1

2

High-throughput

0.479

High

764252

NOC4
Nucleolar complex protein 4

1

6

High-throughput

0.479

High

764238

SPC24
Kinetochore protein SPC24

1

0

Small-scale

0.460

High

764275

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

141346

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

376795

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

406004

RL33A
Large ribosomal subunit protein eL33A

1

0

Small-scale

0.458

High

407068

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408367

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

628083

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

630491

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

631894

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

635124

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

664842

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

688255

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

732726

RL14A
Large ribosomal subunit protein eL14A

1

0

Small-scale

0.458

High

746240

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

752470

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

754362

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

High-throughput

0.458

High

756348

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.458

High

756823

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.458

High

764184

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.458

High

764191

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

764203

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

764206

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

764209

SDA1
Protein SDA1

1

0

High-throughput

0.458

High

764212

PAP2
Poly(A) RNA polymerase protein 2

1

0

Small-scale

0.458

High

764223

RL34A
Large ribosomal subunit protein eL34A

1

0

Small-scale

0.458

High

764231

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

764244

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

764263

SGO1
Shugoshin

1

0

High-throughput

0.458

High

764269

MDN1
Midasin

1

0

Small-scale

0.458

High

764278

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

764281

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

764282

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.458

High

366327

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

491297

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

694747

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

705203

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

764188

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

357505

RLA4
Large ribosomal subunit protein P2B

1

1

Small-scale

0.437

High

399756

RLA1
Large ribosomal subunit protein P1A

1

1

Small-scale

0.437

High

399880

RLA2
Large ribosomal subunit protein P2A

1

1

Small-scale

0.437

High

406138

RL36A
Large ribosomal subunit protein eL36A

1

1

Small-scale

0.437

High

406346

RL15A
Large ribosomal subunit protein eL15A

1

1

Small-scale

0.437

High

472205

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

481644

RL18B
Large ribosomal subunit protein eL18B

1

1

Small-scale

0.437

High

482725

RL19B
Large ribosomal subunit protein eL19

1

1

Small-scale

0.437

High

496051

RLA3
Large ribosomal subunit protein P1B

1

1

Small-scale

0.437

High

764280

RL13A
Large ribosomal subunit protein eL13A

1

1

Small-scale

0.437

High

754432

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

764190

DJP1
DnaJ-like protein 1

1

0

High-throughput

0.426

High

764225

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

764264

FOLE
Folylpolyglutamate synthase

1

0

High-throughput

0.426

High

750063

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

0

High-throughput

0.279

Low

764249

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.279

Low

764265

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.279

Low

764250

NAT3
N-terminal acetyltransferase B complex catalytic subunit NAT3

1

0

High-throughput

0.269

Low

387906

RL39
Large ribosomal subunit protein eL39

1

0

Small-scale

0.249

Low

404846

RL9A
Large ribosomal subunit protein uL6A

1

0

Small-scale

0.249

Low

479117

RL43B
Large ribosomal subunit protein eL43B

1

0

Small-scale

0.249

Low

480684

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

481922

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.249

Low

524316

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

701443

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

706287

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

729926

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

743265

RL32
Large ribosomal subunit protein eL32

1

0

Small-scale

0.249

Low

762215

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

764194

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.249

Low

764201

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

764227

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

764228

RL6A
Large ribosomal subunit protein eL6A

1

0

Small-scale

0.249

Low

764230

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

764234

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

764254

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

764266

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

519946

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

628980

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

764198

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

764229

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.232

Low

764253

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024