Protein: 1433Z
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)

Gene: 1433Z, Ywhaz
Organism: Mus musculus
Interactions: 205
UniProt ID: P63101

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0003016 - respiratory system process
GO:0005634 - nucleus
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

700339

BRAF
Serine/threonine-protein kinase B-raf

3

20

Small-scale

0.829

High

989971

KSR1
Kinase suppressor of Ras 1

2

20

Small-scale

0.726

High

989963

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

5

11

High-throughput

0.712

High

104500

SYGP1
Ras/Rap GTPase-activating protein SynGAP

4

20

High-throughput

0.694

High

990061

MLF1
Myeloid leukemia factor 1

2

1

Small-scale

0.626

High

967094

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

19

High-throughput

0.618

High

972199

1433E
14-3-3 protein epsilon

1

19

High-throughput

0.618

High

989944

1433F
14-3-3 protein eta

1

18

High-throughput

0.618

High

990045

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

Small-scale

0.618

High

990047

1433B
14-3-3 protein beta/alpha

1

18

High-throughput

0.618

High

989966

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

20

Small-scale

0.612

High

990073

HOME1
Homer protein homolog 1

2

20

High-throughput

0.611

High

989992

NEB2
Neurabin-2

2

20

High-throughput

0.584

High

990055

NDEL1
Nuclear distribution protein nudE-like 1

3

20

Small-scale

0.581

High

989948

ARG28
Rho guanine nucleotide exchange factor 28

1

20

Small-scale

0.579

High

205690

REM1
GTP-binding protein REM 1

1

15

Small-scale

0.561

High

990051

DLGP1
Disks large-associated protein 1

2

6

High-throughput

0.558

High

989964

HERC2
E3 ubiquitin-protein ligase HERC2

1

20

High-throughput

0.536

High

989977

DLG4
Disks large homolog 4

1

18

High-throughput

0.536

High

989980

CRK
Adapter molecule crk

1

20

High-throughput

0.536

High

989997

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

20

High-throughput

0.536

High

990004

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

20

High-throughput

0.536

High

990017

FTM
Protein fantom

1

20

High-throughput

0.536

High

990054

TSC1
Hamartin

1

20

High-throughput

0.536

High

399479

GFAP
Glial fibrillary acidic protein

2

20

Small-scale

0.521

High

591112

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.514

High

59599

A2AM57
Inversin

1

20

High-throughput

0.489

High

989955

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

15

High-throughput

0.489

High

990038

RIN1
Ras and Rab interactor 1

1

20

Small-scale

0.481

High

60001

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

108603

G3X9H5
Huntingtin

1

8

High-throughput

0.479

High

109182

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

10

High-throughput

0.479

High

266763

LNX1
E3 ubiquitin-protein ligase LNX

1

20

High-throughput

0.479

High

313174

SYN1
Synapsin-1

1

20

High-throughput

0.479

High

420087

PRIO
Major prion protein

1

1

Small-scale

0.479

High

470769

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.479

High

518669

EF1A1
Elongation factor 1-alpha 1

1

10

High-throughput

0.479

High

530775

TAU
Microtubule-associated protein tau

1

20

Small-scale

0.479

High

542846

RARA
Retinoic acid receptor alpha

1

18

Small-scale

0.479

High

548939

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

19

High-throughput

0.479

High

549492

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

2

High-throughput

0.479

High

553488

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

6

High-throughput

0.479

High

559565

GELS
Gelsolin

1

10

High-throughput

0.479

High

593884

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

1

High-throughput

0.479

High

602286

HSP72
Heat shock-related 70 kDa protein 2

1

14

High-throughput

0.479

High

602916

ENOA
Alpha-enolase

1

4

High-throughput

0.479

High

607872

TPIS
Triosephosphate isomerase

1

3

High-throughput

0.479

High

627463

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.479

High

704208

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

19

High-throughput

0.479

High

723724

CTND1
Catenin delta-1

1

20

Small-scale

0.479

High

725575

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

3

High-throughput

0.479

High

801611

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

857215

NSF
Vesicle-fusing ATPase

1

14

High-throughput

0.479

High

866590

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.479

High

867572

CAPZB
F-actin-capping protein subunit beta

1

7

High-throughput

0.479

High

867925

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

6

High-throughput

0.479

High

873439

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

16

High-throughput

0.479

High

873498

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

1

16

High-throughput

0.479

High

927686

ATX1
Ataxin-1

1

16

High-throughput

0.479

High

951558

LIPA3
Liprin-alpha-3

1

20

High-throughput

0.479

High

968068

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

15

High-throughput

0.479

High

976064

KCAB2
Voltage-gated potassium channel subunit beta-2

1

3

High-throughput

0.479

High

977626

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

13

High-throughput

0.479

High

989678

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

16

High-throughput

0.479

High

989939

ACTG
Actin, cytoplasmic 2

1

17

High-throughput

0.479

High

989940

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

16

High-throughput

0.479

High

989942

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

12

High-throughput

0.479

High

989943

TBA1A
Tubulin alpha-1A chain

1

20

High-throughput

0.479

High

989945

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

1

20

High-throughput

0.479

High

989947

LDB1
LIM domain-binding protein 1

1

1

High-throughput

0.479

High

989949

C1QA
Complement C1q subcomponent subunit A

1

4

High-throughput

0.479

High

989950

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

20

High-throughput

0.479

High

989951

PDE1B
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

1

20

High-throughput

0.479

High

989952

MARK3
MAP/microtubule affinity-regulating kinase 3

1

20

High-throughput

0.479

High

989953

ENAH
Protein enabled homolog

1

20

High-throughput

0.479

High

989954

NF1
Neurofibromin

1

20

High-throughput

0.479

High

989957

PSD3
PH and SEC7 domain-containing protein 3

1

20

High-throughput

0.479

High

989959

Q3TQ10
TSC complex subunit 2

1

20

Small-scale

0.479

High

989960

CAMKV
CaM kinase-like vesicle-associated protein

1

20

High-throughput

0.479

High

989961

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

20

High-throughput

0.479

High

989967

GRDN
Girdin

1

20

High-throughput

0.479

High

989973

PDE1A
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

1

20

High-throughput

0.479

High

989974

CBX5
Chromobox protein homolog 5

1

8

High-throughput

0.479

High

989975

KINH
Kinesin-1 heavy chain

1

20

High-throughput

0.479

High

989976

MYH10
Myosin-10

1

17

High-throughput

0.479

High

989978

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

High-throughput

0.479

High

989981

TFE3
Transcription factor E3

1

20

High-throughput

0.479

High

989982

SYN2
Synapsin-2

1

17

High-throughput

0.479

High

989984

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.479

High

989985

GIT1
ARF GTPase-activating protein GIT1

1

20

High-throughput

0.479

High

989986

Q68FG2
Spectrin beta chain

1

20

High-throughput

0.479

High

989988

SIK3
Serine/threonine-protein kinase SIK3

1

20

High-throughput

0.479

High

989990

BCR
Breakpoint cluster region protein

1

20

High-throughput

0.479

High

989991

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

19

High-throughput

0.479

High

989995

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

15

High-throughput

0.479

High

990001

RIMS3
Regulating synaptic membrane exocytosis protein 3

1

20

High-throughput

0.479

High

990002

FACD2
Fanconi anemia group D2 protein homolog

1

12

High-throughput

0.479

High

990005

EFTU
Elongation factor Tu, mitochondrial

1

11

High-throughput

0.479

High

990006

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

20

High-throughput

0.479

High

990007

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

10

High-throughput

0.479

High

990008

LIPA2
Liprin-alpha-2

1

20

High-throughput

0.479

High

990010

KS6A5
Ribosomal protein S6 kinase alpha-5

1

20

Small-scale

0.479

High

990011

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.479

High

990016

WDR37
WD repeat-containing protein 37

1

20

High-throughput

0.479

High

990019

Q8K1M3
cAMP-dependent protein kinase type II-alpha regulatory subunit

1

5

High-throughput

0.479

High

990021

PACS1
Phosphofurin acidic cluster sorting protein 1

1

10

High-throughput

0.479

High

990023

MATR3
Matrin-3

1

16

High-throughput

0.479

High

990026

IP3KA
Inositol-trisphosphate 3-kinase A

1

2

High-throughput

0.479

High

990027

RFIP5
Rab11 family-interacting protein 5

1

20

High-throughput

0.479

High

990028

MYH9
Myosin-9

1

17

High-throughput

0.479

High

990030

SFPQ
Splicing factor, proline- and glutamine-rich

1

20

High-throughput

0.479

High

990031

Q91VA7
Isocitrate dehydrogenase [NAD] subunit, mitochondrial

1

4

High-throughput

0.479

High

990034

KAD5
Adenylate kinase isoenzyme 5

1

3

High-throughput

0.479

High

990035

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

990037

RHEB
GTP-binding protein Rheb

1

8

High-throughput

0.479

High

990040

ATD3A
ATPase family AAA domain-containing protein 3A

1

11

High-throughput

0.479

High

990041

MYO5A
Unconventional myosin-Va

1

8

High-throughput

0.479

High

990042

HOME3
Homer protein homolog 3

1

20

High-throughput

0.479

High

990044

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

20

High-throughput

0.479

High

990046

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

990048

NRX1A
Neurexin-1

1

4

High-throughput

0.479

High

990049

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

6

High-throughput

0.479

High

990053

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.479

High

990056

ARHG7
Rho guanine nucleotide exchange factor 7

1

20

High-throughput

0.479

High

990058

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

17

High-throughput

0.479

High

990062

PLEC
Plectin

1

20

High-throughput

0.479

High

990063

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

10

High-throughput

0.479

High

990065

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

6

High-throughput

0.479

High

990066

DEMA
Dematin

1

20

High-throughput

0.479

High

990067

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.479

High

990069

NOS1
Nitric oxide synthase 1

1

4

High-throughput

0.479

High

990070

Q9Z1A1
TFG protein

1

7

High-throughput

0.479

High

408245

MBP
Myelin basic protein

1

0

High-throughput

0.458

High

989958

ROGDI
Protein rogdi homolog

1

0

High-throughput

0.458

High

312773

RAD
GTP-binding protein RAD

1

18

Small-scale

0.457

High

990060

ITA2B
Integrin alpha-IIb

1

6

High-throughput

0.457

High

990036

SH3B4
SH3 domain-binding protein 4

1

14

Small-scale

0.457

High

59470

A2AKD7
Alpha-1-syntrophin

1

14

High-throughput

0.445

High

97950

RYR2
Ryanodine receptor 2

1

15

High-throughput

0.445

High

148167

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

11

High-throughput

0.445

High

437052

K1C18
Keratin, type I cytoskeletal 18

1

20

Small-scale

0.445

High

467753

SODC
Superoxide dismutase [Cu-Zn]

1

9

High-throughput

0.445

High

651506

CBL
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.445

High

905809

CAV3
Caveolin-3

1

4

High-throughput

0.445

High

933922

GEM
GTP-binding protein GEM

1

18

Small-scale

0.445

High

989968

LCP2
Lymphocyte cytosolic protein 2

1

20

High-throughput

0.445

High

989970

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

7

High-throughput

0.445

High

989983

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

1

High-throughput

0.445

High

990020

DNM1L
Dynamin-1-like protein

1

12

High-throughput

0.445

High

990022

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

10

High-throughput

0.445

High

990043

PARK7
Parkinson disease protein 7 homolog

1

7

High-throughput

0.445

High

990050

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

10

High-throughput

0.445

High

990071

GAB2
GRB2-associated-binding protein 2

1

20

High-throughput

0.445

High

59041

TANC2
Protein TANC2

1

20

High-throughput

0.437

High

59182

A2A9M5
Dedicator of cytokinesis 7

1

20

High-throughput

0.437

High

72848

B0V2P5
Dmx-like 2

1

13

High-throughput

0.437

High

86340

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

20

High-throughput

0.437

High

237139

STRN
Striatin

1

17

High-throughput

0.437

High

266724

EF1B
Elongation factor 1-beta

1

4

High-throughput

0.437

High

398293

CFAD
Complement factor D

1

4

High-throughput

0.437

High

464660

SPTA1
Spectrin alpha chain, erythrocytic 1

1

20

High-throughput

0.437

High

470795

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.437

High

631782

MTAP2
Microtubule-associated protein 2

1

20

High-throughput

0.437

High

704810

KIF5C
Kinesin heavy chain isoform 5C

1

20

High-throughput

0.437

High

704828

KIF2A
Kinesin-like protein KIF2A

1

20

High-throughput

0.437

High

858162

AINX
Alpha-internexin

1

20

High-throughput

0.437

High

939589

GOGA3
Golgin subfamily A member 3

1

20

High-throughput

0.437

High

941867

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.437

High

989941

ACTS
Actin, alpha skeletal muscle

1

18

High-throughput

0.437

High

989946

EVL
Ena/VASP-like protein

1

20

High-throughput

0.437

High

989962

Q3ZB59
Growth factor receptor bound protein 2-associated protein 2

1

20

High-throughput

0.437

High

989965

KCD16
BTB/POZ domain-containing protein KCTD16

1

18

High-throughput

0.437

High

989969

ARHG2
Rho guanine nucleotide exchange factor 2

1

20

High-throughput

0.437

High

989979

VAT1
Synaptic vesicle membrane protein VAT-1 homolog

1

6

High-throughput

0.437

High

989989

ARHGI
Rho guanine nucleotide exchange factor 18

1

20

High-throughput

0.437

High

989993

MTMR5
Myotubularin-related protein 5

1

20

High-throughput

0.437

High

989994

Q6ZWQ9
Myosin, light chain 12A, regulatory, non-sarcomeric

1

8

High-throughput

0.437

High

989996

TBB2A
Tubulin beta-2A chain

1

16

High-throughput

0.437

High

989998

MAP6
Microtubule-associated protein 6

1

20

High-throughput

0.437

High

989999

ASTRB
Protein Aster-B

1

1

High-throughput

0.437

High

990000

MADD
MAP kinase-activating death domain protein

1

20

High-throughput

0.437

High

990003

Q80W01
AU042671 protein

1

20

High-throughput

0.437

High

990009

APH1A
Gamma-secretase subunit APH-1A

1

3

Small-scale

0.437

High

990012

COR2A
Coronin-2A

1

9

High-throughput

0.437

High

990013

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

20

High-throughput

0.437

High

990014

APH1B
Gamma-secretase subunit APH-1B

1

3

Small-scale

0.437

High

990015

Q8C8C0
Multiple C2 and transmembrane domain-containing protein 1

1

14

High-throughput

0.437

High

990018

RPGF2
Rap guanine nucleotide exchange factor 2

1

20

High-throughput

0.437

High

990024

ARHG6
Rho guanine nucleotide exchange factor 6

1

20

High-throughput

0.437

High

990025

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.437

High

990032

LNX2
Ligand of Numb protein X 2

1

20

High-throughput

0.437

High

990033

WDR7
WD repeat-containing protein 7

1

15

High-throughput

0.437

High

990039

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

20

High-throughput

0.437

High

990052

EF1G
Elongation factor 1-gamma

1

10

High-throughput

0.437

High

990057

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

7

High-throughput

0.437

High

990059

MY18A
Unconventional myosin-XVIIIa

1

20

High-throughput

0.437

High

990064

TRIM3
Tripartite motif-containing protein 3

1

20

High-throughput

0.437

High

990068

CLIP2
CAP-Gly domain-containing linker protein 2

1

20

High-throughput

0.437

High

990072

MTMR1
Phosphatidylinositol-3-phosphate phosphatase MTMR1

1

20

High-throughput

0.437

High

236366

O54737
BCA protein

1

20

High-throughput

0.417

High

989972

SOAT1
Sterol O-acyltransferase 1

1

7

High-throughput

0.407

High

990029

REM2
GTP-binding protein REM 2

1

20

Small-scale

0.407

High

989956

PADI2
Protein-arginine deiminase type-2

1

0

High-throughput

0.249

Low

989987

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.249

Low

963609

SNN
Stannin

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025