Protein: DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3 (D-2HG--pyruvate transhydrogenase DLD3) (EC 1.1.99.40) ((R)-2-hydroxyglutarate--pyruvate transhydrogenase) (D-lactate dehydrogenase [cytochrome] 3) (EC 1.1.2.4) (D-lactate ferricytochrome C oxidoreductase) (D-LCR)

Gene: DLD3
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P39976

Gene Ontology (top 5):
GO:0004458 - D-lactate dehydrogenase (cytochrome) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0019249 - lactate biosynthetic process
GO:0019516 - lactate oxidation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680732

HS104
Heat shock protein 104

3

3

Small-scale

0.633

High

765894

DLD2
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2

1

6

High-throughput

0.618

High

765893

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

765914

HRT3
F-box protein HRT3

1

0

Small-scale

0.549

High

765912

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.541

High

491322

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.536

High

511423

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.536

High

765901

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

541552

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.513

High

765915

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.479

High

419701

RHO1
GTP-binding protein RHO1

1

1

High-throughput

0.479

High

543794

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

692531

ZUO1
Zuotin

1

1

Small-scale

0.479

High

700916

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

703904

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.479

High

753817

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

764950

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

765899

HST2
NAD-dependent protein deacetylase HST2

1

3

High-throughput

0.479

High

765908

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

1

Small-scale

0.479

High

141352

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

407076

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

589023

PYRC
Dihydroorotase

1

0

High-throughput

0.458

High

630199

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

631900

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

690020

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

High-throughput

0.458

High

703630

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

729931

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

752476

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

765892

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

765895

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

765897

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

765898

COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

1

0

Small-scale

0.458

High

765900

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.458

High

765902

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

765904

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

Small-scale

0.458

High

765905

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

494048

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

611735

TRX2
Thioredoxin-2

1

1

Small-scale

0.445

High

694759

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

695976

HSP79
Heat shock protein homolog SSE2

1

6

High-throughput

0.445

High

754439

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

765891

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

765913

HSP42
Heat shock protein 42

1

1

High-throughput

0.445

High

628091

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

662310

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

745670

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

765903

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

High-throughput

0.437

High

765906

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

765910

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

561239

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.426

High

765896

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

358083

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383167

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405642

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

413524

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

425970

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471075

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472210

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

645466

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

700431

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

757984

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

765907

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

765909

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

765911

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024