Protein: CEBPA
CCAAT/enhancer-binding protein alpha (C/EBP alpha)

Gene: CEBPA
Organism: Mus musculus
Interactions: 144
UniProt ID: P53566

Gene Ontology (top 5):
GO:0000050 - urea cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

700391

CEBPB
CCAAT/enhancer-binding protein beta

4

19

Small-scale

0.878

High

921236

JDP2
Jun dimerization protein 2

1

20

High-throughput

0.698

High

718970

CDK4
Cyclin-dependent kinase 4

3

6

Small-scale

0.680

High

921235

CDK2
Cyclin-dependent kinase 2

2

5

Small-scale

0.624

High

921220

CEBPA
CCAAT/enhancer-binding protein alpha

1

19

Small-scale

0.618

High

775486

DDIT3
DNA damage-inducible transcript 3 protein

2

15

Small-scale

0.614

High

148666

HDAC1
Histone deacetylase 1

2

10

Small-scale

0.594

High

921223

WDR5
WD repeat-containing protein 5

2

14

Small-scale

0.594

High

522154

BCL2
Apoptosis regulator Bcl-2

2

4

Small-scale

0.584

High

604507

SPI1
Transcription factor PU.1

2

14

Small-scale

0.584

High

921326

PSD10
26S proteasome non-ATPase regulatory subunit 10

2

7

Small-scale

0.584

High

921231

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

Small-scale

0.561

High

921321

FOXO1
Forkhead box protein O1

1

14

Small-scale

0.534

High

561628

RB
Retinoblastoma-associated protein

1

9

Small-scale

0.501

High

921286

TRIB1
Tribbles homolog 1

1

11

Small-scale

0.501

High

921266

KDM1A
Lysine-specific histone demethylase 1A

1

3

Small-scale

0.500

High

921279

RBBP5
Retinoblastoma-binding protein 5

1

9

Small-scale

0.500

High

921298

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

9

Small-scale

0.500

High

921306

DPY30
Protein dpy-30 homolog

1

1

Small-scale

0.500

High

63096

A5D6Q2
Nuclear receptor coactivator 3

1

16

Small-scale

0.479

High

74265

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.479

High

148559

NCOA3
Nuclear receptor coactivator 3

1

16

Small-scale

0.479

High

205397

PININ
Pinin

1

3

Small-scale

0.479

High

237171

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

312527

ZFR
Zinc finger RNA-binding protein

1

12

Small-scale

0.479

High

373670

MYC
Myc proto-oncogene protein

1

20

Small-scale

0.479

High

465706

TRFL
Lactotransferrin

1

4

Small-scale

0.479

High

476216

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

502198

H2AZ
Histone H2A.Z

1

9

Small-scale

0.479

High

539934

PERM
Myeloperoxidase

1

3

Small-scale

0.479

High

543021

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.479

High

575060

LMNB1
Lamin-B1

1

12

Small-scale

0.479

High

594813

DDX3L
Putative ATP-dependent RNA helicase Pl10

1

7

Small-scale

0.479

High

644270

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

3

High-throughput

0.479

High

718922

CCND3
G1/S-specific cyclin-D3

1

2

Small-scale

0.479

High

832478

LEP
Leptin

1

2

Small-scale

0.479

High

838267

STAT3
Signal transducer and activator of transcription 3

1

8

Small-scale

0.479

High

887484

MCM4
DNA replication licensing factor MCM4

1

9

Small-scale

0.479

High

907002

CCR2
C-C chemokine receptor type 2

1

2

Small-scale

0.479

High

921224

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

3

Small-scale

0.479

High

921225

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

4

Small-scale

0.479

High

921226

RS14
Small ribosomal subunit protein uS11

1

1

Small-scale

0.479

High

921227

RS4X
Small ribosomal subunit protein eS4

1

1

Small-scale

0.479

High

921228

RS25
Small ribosomal subunit protein eS25

1

1

Small-scale

0.479

High

921229

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

10

Small-scale

0.479

High

921230

RS3
Small ribosomal subunit protein uS3

1

1

Small-scale

0.479

High

921232

IMB1
Importin subunit beta-1

1

7

Small-scale

0.479

High

921233

HDAC2
Histone deacetylase 2

1

10

Small-scale

0.479

High

921237

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

9

Small-scale

0.479

High

921238

TOP2A
DNA topoisomerase 2-alpha

1

4

Small-scale

0.479

High

921239

TERA
Transitional endoplasmic reticulum ATPase

1

2

Small-scale

0.479

High

921240

TOP1
DNA topoisomerase 1

1

2

Small-scale

0.479

High

921241

SOX8
Transcription factor SOX-8

1

18

Small-scale

0.479

High

921242

COE1
Transcription factor COE1

1

2

Small-scale

0.479

High

921243

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

Small-scale

0.479

High

921244

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

4

Small-scale

0.479

High

921245

LBR
Delta(14)-sterol reductase LBR

1

1

Small-scale

0.479

High

921246

SMU1
WD40 repeat-containing protein SMU1

1

13

Small-scale

0.479

High

921247

HDGR2
Hepatoma-derived growth factor-related protein 2

1

15

Small-scale

0.479

High

921248

ELNE
Neutrophil elastase

1

8

Small-scale

0.479

High

921251

SIN3A
Paired amphipathic helix protein Sin3a

1

4

Small-scale

0.479

High

921253

KLF3
Krueppel-like factor 3

1

17

Small-scale

0.479

High

921254

ADIPO
Adiponectin

1

2

Small-scale

0.479

High

921255

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

5

Small-scale

0.479

High

921256

EWS
RNA-binding protein EWS

1

6

Small-scale

0.479

High

921257

RAD21
Double-strand-break repair protein rad21 homolog

1

1

Small-scale

0.479

High

921258

MCM7
DNA replication licensing factor MCM7

1

9

Small-scale

0.479

High

921259

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

Small-scale

0.479

High

921260

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

10

Small-scale

0.479

High

921261

RBL1
Retinoblastoma-like protein 1

1

9

Small-scale

0.479

High

921262

NOP58
Nucleolar protein 58

1

5

Small-scale

0.479

High

921263

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

14

Small-scale

0.479

High

921264

RRP5
Protein RRP5 homolog

1

9

Small-scale

0.479

High

921268

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

3

Small-scale

0.479

High

921269

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

Small-scale

0.479

High

921272

MED23
Mediator of RNA polymerase II transcription subunit 23

1

2

Small-scale

0.479

High

921273

SAFB2
Scaffold attachment factor B2

1

10

Small-scale

0.479

High

921274

Q80ZH7
DNA ligase

1

2

Small-scale

0.479

High

921277

PUM3
Pumilio homolog 3

1

2

Small-scale

0.479

High

921278

THOC5
THO complex subunit 5 homolog

1

1

Small-scale

0.479

High

921280

TCRG1
Transcription elongation regulator 1

1

16

Small-scale

0.479

High

921281

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

10

Small-scale

0.479

High

921282

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.479

High

921283

MATR3
Matrin-3

1

7

Small-scale

0.479

High

921284

DDX18
ATP-dependent RNA helicase DDX18

1

12

Small-scale

0.479

High

921287

DDX54
ATP-dependent RNA helicase DDX54

1

14

Small-scale

0.479

High

921289

RFC3
Replication factor C subunit 3

1

8

Small-scale

0.479

High

921290

THOC1
THO complex subunit 1

1

1

Small-scale

0.479

High

921292

MYH9
Myosin-9

1

1

Small-scale

0.479

High

921293

RBM39
RNA-binding protein 39

1

13

Small-scale

0.479

High

921294

IF4A3
Eukaryotic initiation factor 4A-III

1

13

Small-scale

0.479

High

921295

DDX1
ATP-dependent RNA helicase DDX1

1

13

Small-scale

0.479

High

921297

SHRPN
Sharpin

1

1

Small-scale

0.479

High

921299

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

Small-scale

0.479

High

921303

RFC4
Replication factor C subunit 4

1

8

Small-scale

0.479

High

921304

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

6

Small-scale

0.479

High

921305

NXF1
Nuclear RNA export factor 1

1

1

Small-scale

0.479

High

921309

BHE41
Class E basic helix-loop-helix protein 41

1

5

Small-scale

0.479

High

921310

DDX47
Probable ATP-dependent RNA helicase DDX47

1

15

Small-scale

0.479

High

921311

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

6

Small-scale

0.479

High

921312

STAG1
Cohesin subunit SA-1

1

1

Small-scale

0.479

High

921313

NOP56
Nucleolar protein 56

1

5

Small-scale

0.479

High

921315

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

1

Small-scale

0.479

High

921317

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

Small-scale

0.479

High

921318

BRD4
Bromodomain-containing protein 4

1

12

Small-scale

0.479

High

921319

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

4

Small-scale

0.479

High

921320

MTA2
Metastasis-associated protein MTA2

1

9

Small-scale

0.479

High

921322

SRBP1
Sterol regulatory element-binding protein 1

1

20

Small-scale

0.479

High

921323

RFC2
Replication factor C subunit 2

1

9

Small-scale

0.479

High

921324

BUB3
Mitotic checkpoint protein BUB3

1

11

Small-scale

0.479

High

117072

J3QK52
NOC2 like nucleolar associated transcriptional repressor

1

0

Small-scale

0.458

High

921222

RL27
Large ribosomal subunit protein eL27

1

0

Small-scale

0.458

High

921249

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

Small-scale

0.458

High

921250

NOL10
Nucleolar protein 10

1

0

Small-scale

0.458

High

921265

RRP12
RRP12-like protein

1

0

Small-scale

0.458

High

921267

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.458

High

921270

INT7
Integrator complex subunit 7

1

0

Small-scale

0.458

High

921288

INT13
Integrator complex subunit 13

1

0

Small-scale

0.458

High

921291

NOL6
Nucleolar protein 6

1

0

Small-scale

0.458

High

921296

NCOA5
Nuclear receptor coactivator 5

1

0

Small-scale

0.458

High

921302

STEA4
Metalloreductase STEAP4

1

0

Small-scale

0.458

High

921285

TRIB2
Tribbles homolog 2

1

10

Small-scale

0.457

High

59133

PRD16
Histone-lysine N-methyltransferase PRDM16

1

8

Small-scale

0.445

High

86338

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

9

Small-scale

0.437

High

107972

G3UWZ0
Bromodomain adjacent to zinc finger domain protein 1A

1

20

Small-scale

0.437

High

204680

SRSF5
Serine/arginine-rich splicing factor 5

1

12

Small-scale

0.437

High

405584

GRAB
Granzyme B(G,H)

1

4

Small-scale

0.437

High

627459

BIP
Endoplasmic reticulum chaperone BiP

1

6

Small-scale

0.437

High

821231

CSF3R
Granulocyte colony-stimulating factor receptor

1

5

Small-scale

0.437

High

921221

CEBPZ
CCAAT/enhancer-binding protein zeta

1

1

Small-scale

0.437

High

921234

SRSF3
Serine/arginine-rich splicing factor 3

1

17

Small-scale

0.437

High

921252

MYL6
Myosin light polypeptide 6

1

4

Small-scale

0.437

High

921276

NUP93
Nuclear pore complex protein Nup93

1

2

Small-scale

0.437

High

921300

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

Small-scale

0.437

High

921307

RNPS1
RNA-binding protein with serine-rich domain 1

1

8

Small-scale

0.437

High

921308

RETN
Resistin

1

1

Small-scale

0.437

High

921314

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

14

Small-scale

0.437

High

921316

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

Small-scale

0.437

High

920756

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

Small-scale

0.249

Low

921271

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

Small-scale

0.249

Low

921275

NU107
Nuclear pore complex protein Nup107

1

0

Small-scale

0.249

Low

921301

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

Small-scale

0.249

Low

921325

NU160
Nuclear pore complex protein Nup160

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025