Protein: IMDH4
Inosine-5'-monophosphate dehydrogenase 4 (IMP dehydrogenase 4) (IMPD 4) (IMPDH 4) (EC 1.1.1.205)

Gene: IMDH4, IMD4
Organism: Saccharomyces cerevisiae S288C
Interactions: 156
UniProt ID: P50094

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0003729 - mRNA binding
GO:0003938 - IMP dehydrogenase activity
GO:0005737 - cytoplasm
GO:0006177 - GMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

837262

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

8

14

High-throughput

0.970

High

752383

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

3

14

High-throughput

0.855

High

837261

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

3

14

High-throughput

0.843

High

837267

BUD32
EKC/KEOPS complex subunit BUD32

2

2

Small-scale

0.625

High

419922

SNF1
Carbon catabolite-derepressing protein kinase

1

3

Small-scale

0.618

High

762877

IMDH1
Putative inosine-5'-monophosphate dehydrogenase 1

1

14

High-throughput

0.618

High

837310

YRA1
RNA annealing protein YRA1

2

4

Small-scale

0.584

High

705411

HSP78
Heat shock protein 78, mitochondrial

2

1

High-throughput

0.571

High

837271

GIS2
Zinc finger protein GIS2

2

4

High-throughput

0.571

High

491800

HSP71
Heat shock protein SSA1

2

6

High-throughput

0.552

High

768905

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

334503

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.536

High

376851

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.536

High

424885

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.536

High

425362

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.536

High

604301

MAG
DNA-3-methyladenine glycosylase

1

2

High-throughput

0.536

High

605085

XRN1
5'-3' exoribonuclease 1

1

4

High-throughput

0.536

High

628765

RNA14
mRNA 3'-end-processing protein RNA14

1

3

High-throughput

0.536

High

676204

XPO1
Exportin-1

1

1

High-throughput

0.536

High

690811

GSH1
Glutamate--cysteine ligase

1

1

High-throughput

0.536

High

691270

MYO4
Myosin-4

1

2

High-throughput

0.536

High

774809

AIR1
Protein AIR1

1

4

High-throughput

0.536

High

837264

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

High-throughput

0.536

High

837266

YG5B
Uncharacterized RNA-binding protein YGR250C

1

2

High-throughput

0.536

High

837268

PAP2
Poly(A) RNA polymerase protein 2

1

2

High-throughput

0.536

High

837269

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

837272

ELOA1
Elongin-A

1

1

High-throughput

0.536

High

837278

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

837296

MAG2
E3 ubiquitin-protein ligase MAG2

1

2

High-throughput

0.536

High

837302

PUS7
Multisubstrate pseudouridine synthase 7

1

1

High-throughput

0.536

High

837312

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.536

High

480772

RS8A
Small ribosomal subunit protein eS8A

2

2

High-throughput

0.533

High

341818

IPYR
Inorganic pyrophosphatase

1

2

High-throughput

0.515

High

419485

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

1

High-throughput

0.515

High

716196

SKI2
Antiviral helicase SKI2

1

2

High-throughput

0.515

High

837225

YG51
Uncharacterized protein YGR237C

1

1

High-throughput

0.515

High

690549

CDC12
Cell division control protein 12

1

0

High-throughput

0.513

High

732095

SHE2
SWI5-dependent HO expression protein 2

1

0

High-throughput

0.513

High

837292

NKP2
Inner kinetochore subunit NKP2

1

1

High-throughput

0.494

High

334956

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.489

High

550564

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.489

High

615165

BUR1
Serine/threonine-protein kinase BUR1

1

2

High-throughput

0.489

High

791251

KRI1
Protein KRI1

1

1

High-throughput

0.489

High

837300

BRX1
Ribosome biogenesis protein BRX1

1

2

High-throughput

0.489

High

837313

SMC6
Structural maintenance of chromosomes protein 6

1

3

High-throughput

0.489

High

141427

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

407182

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408011

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

410423

SC160
Protein SCP160

1

3

High-throughput

0.479

High

413609

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

479781

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

482351

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

524387

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

535047

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

558147

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

Small-scale

0.479

High

631977

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

645075

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

650336

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

662743

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

692035

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

694124

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

5

High-throughput

0.479

High

730013

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

731595

EAP1
Protein EAP1

1

1

High-throughput

0.479

High

742889

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

748158

AIM4
Altered inheritance of mitochondria protein 4

1

2

High-throughput

0.479

High

752556

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

761985

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.479

High

774122

TM108
Protein TMA108

1

3

High-throughput

0.479

High

797477

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

820062

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

837276

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

837279

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

837281

XRN2
5'-3' exoribonuclease 2

1

4

High-throughput

0.479

High

837282

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

837299

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

837301

SGO1
Shugoshin

1

1

High-throughput

0.479

High

837306

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.479

High

837309

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

628260

SIS1
Protein SIS1

1

3

High-throughput

0.470

High

837308

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

399545

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

450108

HSP73
Heat shock protein SSA3

1

6

High-throughput

0.445

High

494419

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

511963

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

544071

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

560728

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

657748

YJU2
Splicing factor YJU2

1

1

High-throughput

0.445

High

692319

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.445

High

695074

HSP7F
Heat shock protein homolog SSE1

1

8

High-throughput

0.445

High

745013

PBP2
PAB1-binding protein 2

1

2

High-throughput

0.445

High

746405

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

1

High-throughput

0.445

High

757179

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.445

High

763873

IF2P
Eukaryotic translation initiation factor 5B

1

6

High-throughput

0.445

High

766105

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

810388

JJJ2
J protein JJJ2

1

2

High-throughput

0.445

High

837288

RRP5
rRNA biogenesis protein RRP5

1

4

High-throughput

0.445

High

837307

CWC2
Pre-mRNA-splicing factor CWC2

1

2

High-throughput

0.445

High

837311

PUS1
tRNA pseudouridine synthase 1

1

2

High-throughput

0.445

High

356589

H4
Histone H4

1

3

High-throughput

0.437

High

358156

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

383243

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405719

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

426046

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

471152

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

472291

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

480204

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

481183

RL1A
Large ribosomal subunit protein uL1A

1

1

High-throughput

0.437

High

634684

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.437

High

645543

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

700517

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

706373

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

749075

YB8A
Putative uncharacterized protein YBR285W

1

2

Small-scale

0.437

High

762376

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

775778

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.437

High

792501

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.437

High

837273

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

High-throughput

0.437

High

837277

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

837284

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

837286

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.437

High

837289

FAR8
Factor arrest protein 8

1

1

High-throughput

0.437

High

837293

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.437

High

837295

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

837297

URN1
Pre-mRNA-splicing factor URN1

1

2

High-throughput

0.437

High

837303

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

837305

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

423625

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.426

High

700987

SMY2
Protein SMY2

1

0

High-throughput

0.426

High

837270

IST1
Vacuolar protein sorting-associated protein IST1

1

0

High-throughput

0.426

High

837274

IGO1
mRNA stability protein IGO1

1

0

High-throughput

0.426

High

837291

YTH1
mRNA 3'-end-processing protein YTH1

1

0

High-throughput

0.426

High

588149

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.407

High

691391

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

2

High-throughput

0.407

High

744209

MAK5
ATP-dependent RNA helicase MAK5

1

4

High-throughput

0.407

High

761262

CAJ1
Protein CAJ1

1

1

High-throughput

0.407

High

772257

RFC4
Replication factor C subunit 4

1

2

High-throughput

0.407

High

772566

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

809563

RRP41
Exosome complex component SKI6

1

3

High-throughput

0.407

High

810762

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.407

High

837283

GCN5
Histone acetyltransferase GCN5

1

5

High-throughput

0.407

High

837285

CAB5
Dephospho-CoA kinase CAB5

1

2

High-throughput

0.407

High

837290

RRP45
Exosome complex component RRP45

1

3

High-throughput

0.407

High

837298

MHR1
Large ribosomal subunit protein mL67

1

1

High-throughput

0.407

High

837304

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.407

High

757144

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

0

High-throughput

0.282

High

470677

RS25B
Small ribosomal subunit protein eS25B

1

0

High-throughput

0.269

Low

837265

COX18
Cytochrome c oxidase assembly protein COX18, mitochondrial

1

0

High-throughput

0.269

Low

481047

RL23B
Large ribosomal subunit protein uL14B

1

0

High-throughput

0.249

Low

837275

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.249

Low

837294

PEX30
Peroxisomal membrane protein PEX30

1

0

High-throughput

0.249

Low

533769

RSR1
Ras-related protein RSR1

1

0

High-throughput

0.232

Low

778914

RMRP
Ribonuclease MRP protein subunit SNM1

1

0

High-throughput

0.232

Low

816955

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.232

Low

837263

RTF1
RNA polymerase-associated protein RTF1

1

0

High-throughput

0.232

Low

837280

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.232

Low

837287

BUD22
Bud site selection protein 22

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024