Protein: ACS2
Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acyl-activating enzyme 2)

Gene: ACS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P52910

Gene Ontology (top 5):
GO:0003987 - acetate-CoA ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

366597

HSP82
ATP-dependent molecular chaperone HSP82

3

5

High-throughput

0.640

High

491846

HSP71
Heat shock protein SSA1

3

4

High-throughput

0.633

High

695100

HSP7F
Heat shock protein homolog SSE1

2

5

High-throughput

0.628

High

512011

SSB1
Ribosome-associated molecular chaperone SSB1

3

4

High-throughput

0.624

High

340209

KPYK1
Pyruvate kinase 1

2

1

Small-scale

0.611

High

498552

METK1
S-adenosylmethionine synthase 1

2

2

Small-scale

0.611

High

583242

METK2
S-adenosylmethionine synthase 2

2

2

Small-scale

0.611

High

588156

HSP60
Heat shock protein 60, mitochondrial

2

6

High-throughput

0.611

High

700522

RSSA1
Small ribosomal subunit protein uS2A

2

1

High-throughput

0.611

High

857291

SMC6
Structural maintenance of chromosomes protein 6

2

1

High-throughput

0.594

High

407187

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.585

High

753887

RPN1
26S proteasome regulatory subunit RPN1

2

0

High-throughput

0.585

High

857275

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.575

High

544089

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.571

High

857276

RUVB1
RuvB-like protein 1

2

1

High-throughput

0.571

High

558155

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.559

High

797480

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

494459

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

768936

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.552

High

454403

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.536

High

454635

TBA3
Tubulin alpha-3 chain

1

1

High-throughput

0.536

High

746581

OLA1
Obg-like ATPase 1

1

2

High-throughput

0.536

High

753157

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.536

High

857271

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

857285

MDN1
Midasin

1

1

High-throughput

0.536

High

343653

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.513

High

368227

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.513

High

561021

EF3A
Elongation factor 3A

1

0

High-throughput

0.513

High

586427

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.513

High

599189

RIR1
Ribonucleoside-diphosphate reductase large chain 1

1

0

High-throughput

0.513

High

687433

EF2
Elongation factor 2

1

0

High-throughput

0.513

High

837440

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.513

High

857266

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

857270

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

1

High-throughput

0.508

High

477375

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

613827

TKT1
Transketolase 1

1

0

High-throughput

0.493

High

784389

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.489

High

857273

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

419717

RHO1
GTP-binding protein RHO1

1

12

High-throughput

0.479

High

485775

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

606703

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

628272

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

662777

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

680861

HS104
Heat shock protein 104

1

2

High-throughput

0.479

High

688329

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

700991

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

761987

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

857267

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

2

High-throughput

0.479

High

857278

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

857279

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

857289

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

857290

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.479

High

857281

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

3

High-throughput

0.470

High

784172

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.460

High

141430

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

339747

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

358160

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

383248

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

408014

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

426050

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

472295

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

482356

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

631981

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

638810

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

703692

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

730017

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

733667

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

762387

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

775783

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

777124

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.458

High

857269

H3
Histone H3

1

0

High-throughput

0.458

High

857272

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

857274

ESP1
Separin

1

0

High-throughput

0.458

High

857282

SGO1
Shugoshin

1

0

High-throughput

0.458

High

857283

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

857286

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

857287

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

334754

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

High-throughput

0.445

High

424611

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.445

High

440067

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.445

High

478364

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.445

High

560734

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.445

High

705428

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

731125

LHS1
Heat shock protein 70 homolog LHS1

1

5

High-throughput

0.445

High

742894

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.445

High

761269

CAJ1
Protein CAJ1

1

2

High-throughput

0.445

High

857277

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

6

High-throughput

0.445

High

745773

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

857280

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

519975

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.426

High

556169

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

595790

VPS33
Vacuolar protein sorting-associated protein 33

1

0

High-throughput

0.426

High

641004

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

648213

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.426

High

767688

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

629004

SCJ1
DnaJ-related protein SCJ1

1

2

High-throughput

0.407

High

857265

COPA
Coatomer subunit alpha

1

5

High-throughput

0.407

High

701229

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.279

Low

785105

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.279

Low

516894

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.249

Low

524390

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

741198

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

Small-scale

0.249

Low

758004

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

774989

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

857284

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

857268

ZDS2
Protein ZDS2

1

0

High-throughput

0.238

Low

360957

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

399552

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

857288

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024