HitPredict - High confidence protein-protein interactions

Protein: NKG2D
NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)

Gene: NKG2D, Klrk1
Organism: Mus musculus
Interactions: 7
UniProt ID: O54709

Gene Ontology (top 5):
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0006809 - nitric oxide biosynthetic process
GO:0009897 - external side of plasma membrane

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
236332	HCST Hematopoietic cell signal transducer	4	1	Small-scale	0.683	High
236327	TYOBP TYRO protein tyrosine kinase-binding protein	3	2	Small-scale	0.650	High
147987	RAE1B Retinoic acid early-inducible protein 1-beta	1	20	Small-scale	0.647	High
236331	Q3TDZ7 Histocompatibility antigen 60a	1	20	Small-scale	0.501	High
236328	P85A Phosphatidylinositol 3-kinase regulatory subunit alpha	1	4	Small-scale	0.479	High
236329	IL2RG Cytokine receptor common subunit gamma	1	8	Small-scale	0.479	High
236330	FYN Tyrosine-protein kinase Fyn	1	4	Small-scale	0.479	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025