Protein: HSL1
Probable serine/threonine-protein kinase HSL1 (EC 2.7.11.1)

Gene: HSL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: P34244

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000144 - cellular bud neck septin ring
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710950

HSL1
Probable serine/threonine-protein kinase HSL1

2

17

Small-scale

0.821

High

711010

GIN4
Serine/threonine-protein kinase GIN4

2

17

High-throughput

0.793

High

691016

HOG1
Mitogen-activated protein kinase HOG1

1

7

Small-scale

0.785

High

710979

CDH1
APC/C activator protein CDH1

13

8

Small-scale

0.763

High

627899

SIS1
Protein SIS1

2

8

High-throughput

0.755

High

640836

CDC20
APC/C activator protein CDC20

4

7

Small-scale

0.713

High

710957

HSL7
Protein arginine N-methyltransferase HSL7

3

2

Small-scale

0.695

High

627595

NAP1
Nucleosome assembly protein

4

3

High-throughput

0.690

High

412967

KAPB
cAMP-dependent protein kinase type 2

1

9

High-throughput

0.665

High

548526

GCN2
eIF-2-alpha kinase GCN2

1

17

High-throughput

0.665

High

710974

DOHH
Deoxyhypusine hydroxylase

1

0

High-throughput

0.663

High

602651

MCK1
Protein kinase MCK1

1

8

Small-scale

0.647

High

633106

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.647

High

710985

CUS2
Cold sensitive U2 snRNA suppressor 2

1

2

High-throughput

0.647

High

710988

APJ1
J domain-containing protein APJ1

1

10

High-throughput

0.647

High

711014

ARP8
Actin-like protein ARP8

1

10

High-throughput

0.647

High

710987

NAT10
RNA cytidine acetyltransferase

2

1

High-throughput

0.621

High

630992

KCC4
Probable serine/threonine-protein kinase KCC4

1

17

High-throughput

0.621

High

710952

PP2C1
Protein phosphatase 2C homolog 1

1

20

High-throughput

0.621

High

710990

CDC14
Tyrosine-protein phosphatase CDC14

1

12

Small-scale

0.618

High

690177

CDC3
Cell division control protein 3

2

5

Small-scale

0.601

High

690301

CDC11
Cell division control protein 11

2

14

Small-scale

0.594

High

690519

CDC12
Cell division control protein 12

2

5

Small-scale

0.586

High

493609

HSP72
Heat shock protein SSA2

2

14

High-throughput

0.585

High

710999

RRP5
rRNA biogenesis protein RRP5

1

2

High-throughput

0.579

High

628661

CANB
Calcineurin subunit B

1

20

Small-scale

0.553

High

711000

CYK2
Cytokinesis protein 2

1

1

High-throughput

0.541

High

668186

EF1G1
Elongation factor 1-gamma 1

1

2

High-throughput

0.536

High

710983

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.513

High

367927

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.501

High

388962

SYTC
Threonine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.501

High

409977

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.501

High

424843

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.501

High

426441

SYSC
Serine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.501

High

482562

YA11A
Transposon Ty1-A Gag polyprotein

1

3

High-throughput

0.501

High

482619

YE11A
Transposon Ty1-ER1 Gag polyprotein

1

3

High-throughput

0.501

High

526332

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.501

High

563945

SEC2
Rab guanine nucleotide exchange factor SEC2

1

3

High-throughput

0.501

High

693429

PAH1
Phosphatidic acid phosphohydrolase 1

1

1

High-throughput

0.501

High

695936

HSP79
Heat shock protein homolog SSE2

1

20

High-throughput

0.501

High

699663

DRS1
ATP-dependent RNA helicase DRS1

1

7

High-throughput

0.501

High

704205

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

5

High-throughput

0.501

High

710953

DRE2
Fe-S cluster assembly protein DRE2

1

2

High-throughput

0.501

High

710956

SHE3
SWI5-dependent HO expression protein 3

1

1

High-throughput

0.501

High

710963

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

8

High-throughput

0.501

High

710969

SYA
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.501

High

710971

YG4I
Uncharacterized GTP-binding protein YGR210C

1

2

High-throughput

0.501

High

710976

YJ66
Uncharacterized oxidoreductase YJR096W

1

1

High-throughput

0.501

High

710980

YG1B
Uncharacterized protein YGR017W

1

1

High-throughput

0.501

High

710982

SUCB
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.501

High

710991

RNT1
Ribonuclease 3

1

1

High-throughput

0.501

High

710994

NHP10
Non-histone protein 10

1

5

High-throughput

0.501

High

711001

BRE1
E3 ubiquitin-protein ligase BRE1

1

18

High-throughput

0.501

High

711015

YD21A
Transposon Ty2-DR1 Gag polyprotein

1

3

High-throughput

0.501

High

711018

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.501

High

710968

MOB1
DBF2 kinase activator protein MOB1

1

2

High-throughput

0.481

High

711008

NBP2
NAP1-binding protein 2

1

2

High-throughput

0.481

High

711009

RIO1
Serine/threonine-protein kinase RIO1

1

1

Small-scale

0.481

High

711012

MSB4
GTPase-activating protein MSB4

1

2

High-throughput

0.481

High

540192

NMT
Glycylpeptide N-tetradecanoyltransferase

1

0

High-throughput

0.480

High

546521

AMPD
AMP deaminase

1

0

High-throughput

0.480

High

698537

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.480

High

710955

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

0

High-throughput

0.480

High

710961

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.480

High

710964

ARB1
ABC transporter ATP-binding protein ARB1

1

0

High-throughput

0.480

High

710965

RGI2
Respiratory growth induced protein 2

1

0

High-throughput

0.480

High

710972

BUD27
Bud site selection protein 27

1

0

High-throughput

0.480

High

710973

ARC1
tRNA-aminoacylation cofactor ARC1

1

0

High-throughput

0.480

High

710975

BIR1
Protein BIR1

1

0

High-throughput

0.480

High

710977

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.480

High

710978

HGH1
Protein HGH1

1

0

High-throughput

0.480

High

710984

REXO1
RNA exonuclease 1

1

0

High-throughput

0.480

High

710986

EAF7
Chromatin modification-related protein EAF7

1

0

High-throughput

0.480

High

710992

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

0

High-throughput

0.480

High

710993

NGL2
RNA exonuclease NGL2

1

0

High-throughput

0.480

High

710998

MGR3
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3

1

0

High-throughput

0.480

High

711003

HBT1
Protein HBT1

1

0

High-throughput

0.480

High

711004

LOT6
NAD(P)H-dependent FMN reductase LOT6

1

0

High-throughput

0.480

High

711005

AB140
tRNA(Thr)

1

0

High-throughput

0.480

High

711006

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.480

High

711007

YIG1
Protein YIG1

1

0

High-throughput

0.480

High

711013

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.480

High

629549

CDC10
Cell division control protein 10

1

9

High-throughput

0.479

High

661838

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

664750

BMH1
Protein BMH1

1

20

High-throughput

0.479

High

705010

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.479

High

710951

BMH2
Protein BMH2

1

20

High-throughput

0.479

High

710989

H3
Histone H3

1

5

High-throughput

0.479

High

710996

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

711002

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

711016

LAS17
Proline-rich protein LAS17

1

1

Small-scale

0.479

High

711017

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.479

High

566160

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

581101

IF5A2
Eukaryotic translation initiation factor 5A-2

1

1

High-throughput

0.457

High

692737

SPT16
FACT complex subunit SPT16

1

3

High-throughput

0.457

High

698228

CACP
Carnitine O-acetyltransferase, mitochondrial

1

1

High-throughput

0.457

High

698253

CDC13
Cell division control protein 13

1

1

High-throughput

0.457

High

710629

PRX1
Peroxiredoxin PRX1, mitochondrial

1

4

High-throughput

0.457

High

710958

UBX7
UBX domain-containing protein 7

1

1

High-throughput

0.457

High

710960

GLO3
ADP-ribosylation factor GTPase-activating protein GLO3

1

6

High-throughput

0.457

High

710967

VPS27
Vacuolar protein sorting-associated protein 27

1

2

High-throughput

0.457

High

710997

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.457

High

490814

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

694421

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

343581

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

612937

AIM17
Probable oxidoreductase AIM17

1

0

High-throughput

0.261

Low

693646

SPS19
Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]

1

0

High-throughput

0.261

Low

710954

PANB
3-methyl-2-oxobutanoate hydroxymethyltransferase

1

0

High-throughput

0.261

Low

710959

YB8A
Putative uncharacterized protein YBR285W

1

0

High-throughput

0.261

Low

710962

REV7
DNA polymerase zeta processivity subunit

1

0

High-throughput

0.261

Low

710966

MEP1
Ammonium transporter MEP1

1

0

High-throughput

0.261

Low

710970

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.261

Low

710981

YG3W
Uncharacterized protein YGR168C

1

0

High-throughput

0.261

Low

710995

YM30
Uncharacterized membrane protein YMR155W

1

0

High-throughput

0.261

Low

711011

RBD2
Rhomboid-type serine protease 2

1

0

High-throughput

0.261

Low

141638

COQ4
Ubiquinone biosynthesis protein COQ4, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024