HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: S4A7 (Q9Y6M7)
Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7)
Gene: SLC4A7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1214
+	Hs
		564763 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		545733 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		1331018 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		892709 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		951507 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		894643 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		901109 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		436601 RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45		S4A7_HUMAN (1-1214): 0: 1851: 100.00
+	Hs
		392671 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392646 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392728 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392666 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392673 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392667 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74
+	Hs
		392669 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		B3A2_HUMAN (54-258): 1.11e-58: 223: 34.74