Protein: DCP2
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Protein PSU1) (mRNA-decapping enzyme subunit 2)

Gene: DCP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P53550

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 - P-body
GO:0003682 - chromatin binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862717

DCP1
mRNA-decapping enzyme subunit 1

12

1

Small-scale

0.981

High

862695

DCP2
m7GpppN-mRNA hydrolase

2

1

Small-scale

0.793

High

766466

EDC3
Enhancer of mRNA-decapping protein 3

16

4

Small-scale

0.764

High

635893

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

8

3

Small-scale

0.749

High

675762

RENT1
ATP-dependent helicase NAM7

8

1

Small-scale

0.744

High

800702

SCD6
Protein SCD6

7

2

Small-scale

0.741

High

761995

DHH1
ATP-dependent RNA helicase DHH1

5

2

Small-scale

0.716

High

605098

XRN1
5'-3' exoribonuclease 1

5

2

Small-scale

0.713

High

810521

LSM1
Sm-like protein LSm1

4

2

Small-scale

0.694

High

862699

LSM3
U6 snRNA-associated Sm-like protein LSm3

3

1

High-throughput

0.647

High

747142

TTL
Probable tubulin--tyrosine ligase PBY1

1

0

Small-scale

0.645

High

862702

RPM2
Ribonuclease P protein component, mitochondrial

3

0

Small-scale

0.637

High

728289

DEF1
RNA polymerase II degradation factor 1

3

0

Small-scale

0.630

High

811651

LSM8
U6 snRNA-associated Sm-like protein LSm8

2

2

High-throughput

0.603

High

756545

KOG1
Target of rapamycin complex 1 subunit KOG1

2

0

High-throughput

0.600

High

676244

XPO1
Exportin-1

2

0

Small-scale

0.598

High

767802

LSM4
U6 snRNA-associated Sm-like protein LSm4

2

0

High-throughput

0.594

High

664516

HRR25
Casein kinase I homolog HRR25

2

0

Small-scale

0.585

High

410432

SC160
Protein SCP160

2

1

Small-scale

0.584

High

512184

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.576

High

862712

MAK21
Ribosome biogenesis protein MAK21

2

0

High-throughput

0.563

High

758083

BFR1
Nuclear segregation protein BFR1

2

0

Small-scale

0.559

High

494575

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

767044

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.518

High

862696

CAF40
Protein CAF40

1

0

High-throughput

0.518

High

509441

CDC24
Cell division control protein 24

1

0

High-throughput

0.513

High

733354

SPO14
Phospholipase D1

1

1

High-throughput

0.508

High

746321

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.508

High

859748

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.493

High

862714

RLM1
Transcription factor RLM1

1

0

High-throughput

0.493

High

141669

YA11B
Truncated transposon Ty1-A Gag-Pol polyprotein

1

0

High-throughput

0.486

High

396186

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.486

High

417593

PHSG
Glycogen phosphorylase

1

0

High-throughput

0.486

High

442932

LEUR
Regulatory protein LEU3

1

0

High-throughput

0.486

High

619157

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.486

High

629436

PUF4
Pumilio homology domain family member 4

1

0

High-throughput

0.486

High

710469

TOD6
Transcriptional regulatory protein TOD6

1

0

High-throughput

0.486

High

731340

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.486

High

746175

STU1
Protein STU1

1

0

High-throughput

0.486

High

765145

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.486

High

809752

CTK3
CTD kinase subunit gamma

1

0

High-throughput

0.486

High

862698

DNM1
Dynamin-related protein DNM1

1

0

High-throughput

0.486

High

862701

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

High-throughput

0.486

High

862710

GRE2
NADPH-dependent methylglyoxal reductase GRE2

1

0

High-throughput

0.486

High

862716

AHC1
Protein AHC1

1

0

High-throughput

0.486

High

696522

TOR2
Serine/threonine-protein kinase TOR2

1

3

High-throughput

0.481

High

715225

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.481

High

862706

STE20
Serine/threonine-protein kinase STE20

1

0

Small-scale

0.480

High

366665

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

424115

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

High-throughput

0.464

High

376875

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

392168

H2A1
Histone H2A.1

1

0

Small-scale

0.458

High

540614

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.458

High

549754

STI1
Heat shock protein STI1

1

0

Small-scale

0.458

High

554705

HSP26
Heat shock protein 26

1

0

Small-scale

0.458

High

622056

SSD1
Protein SSD1

1

0

Small-scale

0.458

High

632001

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.458

High

636695

CDC48
Cell division control protein 48

1

0

Small-scale

0.458

High

662903

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

730657

EF1G2
Elongation factor 1-gamma 2

1

0

Small-scale

0.458

High

730871

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.458

High

731513

DOA1
Protein DOA1

1

0

Small-scale

0.458

High

774129

TM108
Protein TMA108

1

0

High-throughput

0.458

High

775799

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

797500

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

858933

EDC1
Enhancer of mRNA-decapping protein 1

1

0

Small-scale

0.458

High

860332

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

862697

NST1
Stress response protein NST1

1

0

Small-scale

0.458

High

862703

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.458

High

862705

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

Small-scale

0.458

High

862707

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

862709

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

862711

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

862713

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

491977

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

423884

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

Small-scale

0.437

High

424634

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

854646

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

862708

NEW1
[NU+] prion formation protein 1

1

0

High-throughput

0.426

High

636233

FUB1
Silencing boundary-establishment protein FUB1

1

0

High-throughput

0.265

Low

732083

MGR3L
Protein MRG3-like

1

0

High-throughput

0.265

Low

743399

AP2A
AP-2 complex subunit alpha

1

0

High-throughput

0.265

Low

775922

VLD1
Vacuole localized DSC protein 1

1

0

High-throughput

0.265

Low

775952

INA22
Inner membrane assembly complex subunit 22

1

0

High-throughput

0.265

Low

857034

NUP84
Nucleoporin NUP84

1

0

High-throughput

0.265

Low

862715

YO093
Uncharacterized protein YOR093C

1

0

High-throughput

0.265

Low

862704

TRS31
Trafficking protein particle complex subunit 31

1

0

High-throughput

0.251

Low

710860

ZRT3
Zinc-regulated transporter 3

1

0

High-throughput

0.249

Low

744331

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

762422

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

784278

VATH
V-type proton ATPase subunit H

1

0

Small-scale

0.249

Low

862700

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

811684

YJZ3
Putative uncharacterized protein YJR023C

1

0

High-throughput

0.238

Low

760782

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024