Protein: SPC25
Kinetochore protein SPC25

Gene: SPC25
Organism: Saccharomyces cerevisiae S288C
Interactions: 114
UniProt ID: P40014

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0031262 - Ndc80 complex
GO:0051301 - cell division

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

766823

SPC24
Kinetochore protein SPC24

27

0

Small-scale

0.737

High

766787

NDC80
Kinetochore protein NDC80

14

0

Small-scale

0.730

High

766797

CENPT
Inner kinetochore subunit CNN1

7

0

Small-scale

0.721

High

766790

DSN1
Kinetochore-associated protein DSN1

10

0

Small-scale

0.720

High

708001

NUF2
Kinetochore protein NUF2

6

0

Small-scale

0.706

High

763936

MTW1
Kinetochore-associated protein MTW1

4

0

Small-scale

0.669

High

766807

SP105
Spindle pole body component SPC105

3

0

Small-scale

0.633

High

766815

MPS1
Serine/threonine-protein kinase MPS1

2

0

Small-scale

0.592

High

766801

NNF1
Kinetochore-associated protein NNF1

2

0

High-throughput

0.576

High

766784

SPC25
Kinetochore protein SPC25

2

0

Small-scale

0.570

High

766819

ADA2
Transcriptional adapter 2

2

0

High-throughput

0.570

High

766841

NSL1
Kinetochore-associated protein NSL1

2

0

Small-scale

0.569

High

766792

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.486

High

641131

DAL80
Nitrogen regulatory protein DAL80

1

1

High-throughput

0.481

High

757068

SKN7
Transcription factor SKN7

1

1

High-throughput

0.481

High

766793

GZF3
Protein GZF3

1

1

High-throughput

0.481

High

766802

HMS2
Probable transcription factor HMS2

1

1

High-throughput

0.481

High

766798

STU2
Protein STU2

1

0

Small-scale

0.480

High

409842

NOT2
General negative regulator of transcription subunit 2

1

0

High-throughput

0.460

High

424955

GCR1
Glycolytic genes transcriptional activator GCR1

1

0

High-throughput

0.460

High

436836

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.460

High

452102

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.460

High

542126

CYC8
General transcriptional corepressor CYC8

1

0

High-throughput

0.460

High

549816

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

High-throughput

0.460

High

579795

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.460

High

585870

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.460

High

586491

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.460

High

605651

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

622029

SSD1
Protein SSD1

1

0

High-throughput

0.460

High

627623

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.460

High

635867

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.460

High

680084

DEP1
Transcriptional regulatory protein DEP1

1

0

High-throughput

0.460

High

690021

AROG
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited

1

0

High-throughput

0.460

High

698547

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.460

High

702669

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

703219

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.460

High

703631

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

706006

NIP80
Protein NIP100

1

0

High-throughput

0.460

High

728694

BDF1
Bromodomain-containing factor 1

1

0

High-throughput

0.460

High

733404

SPC34
DASH complex subunit SPC34

1

0

High-throughput

0.460

High

754238

RSC30
Chromatin structure-remodeling complex protein RSC30

1

0

High-throughput

0.460

High

754275

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.460

High

756474

SSP1
Sporulation-specific protein 1

1

0

High-throughput

0.460

High

763207

MBP1
Transcription factor MBP1

1

0

High-throughput

0.460

High

763667

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.460

High

765466

LIS1
Nuclear distribution protein PAC1

1

0

High-throughput

0.460

High

766786

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.460

High

766788

FKH1
Fork head protein homolog 1

1

0

High-throughput

0.460

High

766789

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.460

High

766791

MND2
Anaphase-promoting complex subunit MND2

1

0

High-throughput

0.460

High

766794

EPL1
Enhancer of polycomb-like protein 1

1

0

High-throughput

0.460

High

766805

PHO23
Transcriptional regulatory protein PHO23

1

0

High-throughput

0.460

High

766806

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

766808

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.460

High

766812

SOK2
Protein SOK2

1

0

High-throughput

0.460

High

766816

DAD4
DASH complex subunit DAD4

1

0

High-throughput

0.460

High

766817

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.460

High

766818

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

766820

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

766827

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

766828

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

766829

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.460

High

766834

MFG1
Morphogenetic regulator of filamentous growth protein 1

1

0

High-throughput

0.460

High

766839

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

766840

YP022
Zinc finger protein YPR022C

1

0

High-throughput

0.460

High

766842

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.460

High

766844

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.460

High

766845

RLF2
Chromatin assembly factor 1 subunit p90

1

0

High-throughput

0.460

High

662326

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

748276

CENPU
Inner kinetochore subunit AME1

1

0

Small-scale

0.458

High

766809

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

766822

KRE28
Spindle pole body component KRE28

1

0

High-throughput

0.458

High

766837

SGO1
Shugoshin

1

0

High-throughput

0.458

High

766826

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

689259

SP110
Spindle pole body component 110

1

0

Small-scale

0.426

High

694773

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.426

High

731317

DYHC
Dynein heavy chain, cytoplasmic

2

0

High-throughput

0.310

High

746728

FL2D
Protein MUM2

2

0

High-throughput

0.310

High

766795

FAR7
Factor arrest protein 7

2

0

High-throughput

0.306

High

734308

JNM1
Nuclear migration protein JNM1

2

0

High-throughput

0.304

High

766832

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.269

Low

732621

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

High-throughput

0.265

Low

141740

THP2
THO complex subunit THP2

1

0

High-throughput

0.251

Low

629729

STE50
Protein STE50

1

0

High-throughput

0.251

Low

634951

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

752794

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

753564

ETP1
RING finger protein ETP1

1

0

High-throughput

0.251

Low

755138

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

756501

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.251

Low

759224

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

764732

VPS52
Vacuolar protein sorting-associated protein 52

1

0

High-throughput

0.251

Low

766785

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

766796

KEG1
Beta-1,6-glucan synthesis-associated protein KEG1

1

0

High-throughput

0.251

Low

766799

STB2
Protein STB2

1

0

High-throughput

0.251

Low

766800

ATG36
Autophagy-related protein 36

1

0

High-throughput

0.251

Low

766803

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.251

Low

766804

ASE1
Anaphase spindle elongation protein

1

0

High-throughput

0.251

Low

766810

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

766811

PXR1
Protein PXR1

1

0

High-throughput

0.251

Low

766813

BSC5
Bypass of stop codon protein 5

1

0

High-throughput

0.251

Low

766821

CEF1
Pre-mRNA-splicing factor CEF1

1

0

High-throughput

0.251

Low

766830

IRC3
Putative ATP-dependent helicase IRC3

1

0

High-throughput

0.251

Low

766831

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.251

Low

766833

ATG20
Autophagy-related protein 20

1

0

High-throughput

0.251

Low

766836

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.251

Low

766838

YP257
Uncharacterized membrane protein YPL257W

1

0

High-throughput

0.251

Low

766843

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.251

Low

766846

HPH1
Protein HPH1

1

0

High-throughput

0.251

Low

766814

FAR11
Factor arrest protein 11

1

0

High-throughput

0.249

Low

766824

FAR8
Factor arrest protein 8

1

0

High-throughput

0.249

Low

766825

FAR10
Factor arrest protein 10

1

0

High-throughput

0.249

Low

766835

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low

592912

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024