Protein: NCBP1
Nuclear cap-binding protein complex subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) (Glycolysis regulation protein 3) (Protein SUT1) (Suppressor of TOP1 protein)

Gene: NCBP1, STO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 146
UniProt ID: P34160

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000243 - commitment complex
GO:0000339 - RNA cap binding
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710232

NCBP2
Nuclear cap-binding protein subunit 2

20

8

Small-scale

0.988

High

710199

NOP3
Serine/arginine

7

11

Small-scale

0.951

High

710197

NAM8
Protein NAM8

5

4

Small-scale

0.919

High

696629

RU1A
U1 small nuclear ribonucleoprotein A

6

0

Small-scale

0.894

High

710175

IF4F2
Eukaryotic initiation factor 4F subunit p130

4

6

High-throughput

0.892

High

710198

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

4

6

High-throughput

0.892

High

710158

YRA2
RNA annealing protein YRA2

6

0

Small-scale

0.887

High

376713

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

4

3

Small-scale

0.886

High

710174

IF4F1
Eukaryotic initiation factor 4F subunit p150

3

4

High-throughput

0.855

High

710193

NRD1
Protein NRD1

4

0

Small-scale

0.853

High

697196

BRR2
Pre-mRNA-splicing helicase BRR2

3

7

High-throughput

0.847

High

710168

NAB3
Nuclear polyadenylated RNA-binding protein 3

3

0

High-throughput

0.811

High

415939

DED1
ATP-dependent RNA helicase DED1

2

3

Small-scale

0.806

High

710235

CWC2
Pre-mRNA-splicing factor CWC2

2

1

High-throughput

0.789

High

693981

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

2

6

High-throughput

0.759

High

598570

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

2

4

High-throughput

0.754

High

710155

NCBP1
Nuclear cap-binding protein complex subunit 1

2

1

High-throughput

0.754

High

710228

SUB2
ATP-dependent RNA helicase SUB2

2

4

Small-scale

0.754

High

710237

YRA1
RNA annealing protein YRA1

2

6

Small-scale

0.754

High

710205

IMA1
Importin subunit alpha

7

5

High-throughput

0.742

High

485490

SSBP1
Single-stranded nucleic acid-binding protein

1

7

High-throughput

0.691

High

703190

PRP40
Pre-mRNA-processing protein PRP40

4

1

High-throughput

0.691

High

710182

SMD3
Small nuclear ribonucleoprotein Sm D3

4

1

High-throughput

0.691

High

710212

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

5

High-throughput

0.691

High

710223

SMD2
Small nuclear ribonucleoprotein Sm D2

4

2

High-throughput

0.691

High

710229

LUC7
Protein LUC7

4

2

High-throughput

0.691

High

710177

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

1

High-throughput

0.686

High

710218

RU1C
U1 small nuclear ribonucleoprotein C

5

0

High-throughput

0.684

High

710192

THO2
THO complex subunit 2

4

2

Small-scale

0.678

High

710195

RUXF
Small nuclear ribonucleoprotein F

4

1

High-throughput

0.678

High

710222

IMB1
Importin subunit beta-1

4

1

High-throughput

0.678

High

424842

IF4E
Eukaryotic translation initiation factor 4E

3

1

High-throughput

0.667

High

710217

RSE1
Pre-mRNA-splicing factor RSE1

3

2

High-throughput

0.662

High

615138

BUR1
Serine/threonine-protein kinase BUR1

4

0

Small-scale

0.661

High

710188

SNU71
U1 small nuclear ribonucleoprotein component SNU71

4

0

High-throughput

0.661

High

710202

SMD1
Small nuclear ribonucleoprotein Sm D1

4

0

High-throughput

0.661

High

710213

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

4

0

Small-scale

0.660

High

704651

PRP8
Pre-mRNA-splicing factor 8

3

1

High-throughput

0.656

High

568867

HPR1
THO complex subunit HPR1

4

0

Small-scale

0.648

High

687682

BTAF1
TATA-binding protein-associated factor MOT1

1

2

Small-scale

0.647

High

710247

MEX67
mRNA export factor MEX67

3

2

Small-scale

0.640

High

710219

BUR2
Protein BUR2

3

0

Small-scale

0.634

High

410349

SC160
Protein SCP160

2

3

High-throughput

0.621

High

634119

SRO9
RNA-binding protein SRO9

2

4

High-throughput

0.621

High

710196

SEN1
Helicase SEN1

2

2

High-throughput

0.621

High

710203

CUS1
Cold sensitive U2 snRNA suppressor 1

2

1

High-throughput

0.621

High

554213

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

4

High-throughput

0.618

High

633935

GBP2
Serine/arginine

1

6

Small-scale

0.618

High

697369

CHD1
Chromo domain-containing protein 1

1

1

High-throughput

0.618

High

710167

HRB1
Serine/arginine

1

5

Small-scale

0.618

High

710248

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

7

Small-scale

0.618

High

657725

YJU2
Splicing factor YJU2

3

0

High-throughput

0.616

High

710178

RUXG
Small nuclear ribonucleoprotein G

3

0

High-throughput

0.616

High

557983

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

0

Small-scale

0.613

High

392093

H2A1
Histone H2A.1

2

0

High-throughput

0.595

High

514248

NHP6B
Non-histone chromosomal protein 6B

2

2

High-throughput

0.588

High

710161

HEK2
Heterogeneous nuclear rnp K-like protein 2

2

5

High-throughput

0.588

High

655695

PRP45
Pre-mRNA-processing protein 45

2

1

High-throughput

0.584

High

691962

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

2

1

Small-scale

0.584

High

692281

PRP19
Pre-mRNA-processing factor 19

2

1

High-throughput

0.584

High

710173

PRP39
Pre-mRNA-processing factor 39

2

4

High-throughput

0.584

High

710181

PRP17
Pre-mRNA-processing factor 17

2

1

High-throughput

0.584

High

710215

SYF1
Pre-mRNA-splicing factor SYF1

2

3

High-throughput

0.584

High

710233

RU2A
U2 small nuclear ribonucleoprotein A'

2

2

High-throughput

0.584

High

710241

PRP46
Pre-mRNA-splicing factor PRP46

2

2

High-throughput

0.584

High

710243

AIR2
Protein AIR2

2

1

High-throughput

0.567

High

693001

RPD3
Histone deacetylase RPD3

2

0

High-throughput

0.563

High

710180

MSH4
MutS protein homolog 4

2

0

High-throughput

0.563

High

586478

PRP9
Pre-mRNA-splicing factor PRP9

2

0

High-throughput

0.559

High

710156

MTR2
mRNA transport regulator MTR2

2

0

Small-scale

0.559

High

710220

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.559

High

710240

RUXE
Small nuclear ribonucleoprotein E

2

0

Small-scale

0.559

High

589423

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

4

High-throughput

0.553

High

622309

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

4

High-throughput

0.553

High

493596

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

710194

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.547

High

710185

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.493

High

470969

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.489

High

710245

CMR1
DNA damage-binding protein CMR1

1

3

High-throughput

0.481

High

710160

MUD2
Splicing factor MUD2

1

0

Small-scale

0.480

High

675934

XPO1
Exportin-1

1

2

Small-scale

0.479

High

692389

PRP21
Pre-mRNA-splicing factor PRP21

1

1

High-throughput

0.479

High

710159

SN114
Pre-mRNA-splicing factor SNU114

1

1

High-throughput

0.479

High

710179

MLP2
Protein MLP2

1

2

High-throughput

0.479

High

710184

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.479

High

710187

SF3B1
U2 snRNP component HSH155

1

5

High-throughput

0.479

High

710189

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.479

High

710209

CEF1
Pre-mRNA-splicing factor CEF1

1

1

High-throughput

0.479

High

710221

YTH1
mRNA 3'-end-processing protein YTH1

1

2

Small-scale

0.479

High

710225

CFT1
Protein CFT1

1

2

High-throughput

0.479

High

710227

PRP11
Pre-mRNA-splicing factor PRP11

1

1

High-throughput

0.479

High

710238

BBP
Branchpoint-bridging protein

1

1

Small-scale

0.479

High

710239

CLF1
Pre-mRNA-splicing factor CLF1

1

3

High-throughput

0.479

High

710242

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

595010

NUP1
Nucleoporin NUP1

1

1

High-throughput

0.470

High

692735

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.470

High

710201

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

2

High-throughput

0.470

High

691014

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.460

High

141729

THP2
THO complex subunit THP2

1

0

High-throughput

0.458

High

627893

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

629367

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

661817

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688185

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

704309

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

706132

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.458

High

710162

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

710163

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

710164

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

710166

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

710170

PCF11
Protein PCF11

1

0

Small-scale

0.458

High

710183

SAD1
Pre-mRNA-splicing factor SAD1

1

0

High-throughput

0.458

High

710186

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.458

High

710190

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

710191

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

710207

ESP1
Separin

1

0

High-throughput

0.458

High

710208

CWC21
Pre-mRNA-splicing factor CWC21

1

0

High-throughput

0.458

High

710211

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

710214

CTK1
CTD kinase subunit alpha

1

0

Small-scale

0.458

High

710224

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

710231

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

0

High-throughput

0.458

High

710234

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

710236

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

490798

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

510799

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

560626

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.445

High

710165

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.426

High

710171

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

710200

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

367920

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

478064

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.407

High

710157

LHS1
Heat shock protein 70 homolog LHS1

1

4

High-throughput

0.407

High

710176

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

710226

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

710246

BRR1
Pre-mRNA-splicing factor BRR1

2

0

High-throughput

0.313

High

350864

YPT1
GTP-binding protein YPT1

1

0

Small-scale

0.249

Low

598620

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.249

Low

710172

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

710204

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.249

Low

710206

ELP4
Elongator complex protein 4

1

0

High-throughput

0.249

Low

710210

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

Small-scale

0.249

Low

710230

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.249

Low

705004

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

710169

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

710216

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low

710244

YP064
Uncharacterized protein YPR064W

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024