Protein: NCBP2
Nuclear cap-binding protein subunit 2 (20 kDa nuclear cap-binding protein) (NCBP 20 kDa subunit) (CBP20)

Gene: NCBP2, CBC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 199
UniProt ID: Q08920

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000243 - commitment complex
GO:0000339 - RNA cap binding
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710232

NCBP1
Nuclear cap-binding protein complex subunit 1

20

8

Small-scale

0.988

High

696674

RU1A
U1 small nuclear ribonucleoprotein A

7

1

Small-scale

0.960

High

863174

NRD1
Protein NRD1

6

2

Small-scale

0.947

High

960476

NAM8
Protein NAM8

6

16

Small-scale

0.943

High

996588

YRA1
RNA annealing protein YRA1

6

15

Small-scale

0.931

High

962600

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

5

20

Small-scale

0.922

High

965508

NOP3
Serine/arginine

5

20

Small-scale

0.922

High

980235

RSE1
Pre-mRNA-splicing factor RSE1

5

5

Small-scale

0.922

High

376958

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

5

19

Small-scale

0.915

High

977616

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

6

0

Small-scale

0.894

High

586535

PRP9
Pre-mRNA-splicing factor PRP9

4

2

Small-scale

0.873

High

758930

NAB3
Nuclear polyadenylated RNA-binding protein 3

4

0

High-throughput

0.849

High

731492

YRA2
RNA annealing protein YRA2

4

0

High-throughput

0.836

High

775728

MSL1
U2 small nuclear ribonucleoprotein B''

3

20

Small-scale

0.827

High

996583

RU2A
U2 small nuclear ribonucleoprotein A'

3

5

Small-scale

0.827

High

996584

CWC2
Pre-mRNA-splicing factor CWC2

3

9

High-throughput

0.827

High

861434

YG5B
Uncharacterized RNA-binding protein YGR250C

2

18

High-throughput

0.775

High

633997

GBP2
Serine/arginine

2

19

High-throughput

0.754

High

971699

CUS1
Cold sensitive U2 snRNA suppressor 1

2

2

Small-scale

0.754

High

991151

PRP11
Pre-mRNA-splicing factor PRP11

2

4

Small-scale

0.754

High

996602

HSH49
Protein HSH49

2

18

High-throughput

0.754

High

972930

IMA1
Importin subunit alpha

8

5

Small-scale

0.742

High

996604

MEX67
mRNA export factor MEX67

7

3

Small-scale

0.736

High

991484

LUC7
Protein LUC7

6

2

Small-scale

0.730

High

986150

IMB1
Importin subunit beta-1

6

4

High-throughput

0.727

High

692091

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

6

1

Small-scale

0.723

High

986604

SMD2
Small nuclear ribonucleoprotein Sm D2

5

2

High-throughput

0.714

High

704730

PRP8
Pre-mRNA-splicing factor 8

4

3

High-throughput

0.686

High

766970

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

4

High-throughput

0.686

High

860159

SNU71
U1 small nuclear ribonucleoprotein component SNU71

5

0

Small-scale

0.684

High

703283

PRP40
Pre-mRNA-processing protein PRP40

4

5

Small-scale

0.676

High

763253

PRP39
Pre-mRNA-processing factor 39

4

16

Small-scale

0.676

High

977593

PRP42
U1 small nuclear ribonucleoprotein component PRP42

4

20

Small-scale

0.676

High

765166

IF4F2
Eukaryotic initiation factor 4F subunit p130

6

14

Small-scale

0.668

High

416100

DED1
ATP-dependent RNA helicase DED1

3

12

Small-scale

0.664

High

985136

RU1C
U1 small nuclear ribonucleoprotein C

4

0

Small-scale

0.648

High

558302

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

1

Small-scale

0.640

High

657774

YJU2
Splicing factor YJU2

3

1

High-throughput

0.640

High

692369

PRP19
Pre-mRNA-processing factor 19

3

8

High-throughput

0.640

High

697273

BRR2
Pre-mRNA-splicing helicase BRR2

3

16

High-throughput

0.640

High

731782

SN114
Pre-mRNA-splicing factor SNU114

3

9

High-throughput

0.640

High

778642

PRP17
Pre-mRNA-processing factor 17

3

5

High-throughput

0.640

High

795429

SMD3
Small nuclear ribonucleoprotein Sm D3

3

3

High-throughput

0.640

High

866185

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

3

1

High-throughput

0.640

High

977084

CEF1
Pre-mRNA-splicing factor CEF1

3

3

High-throughput

0.640

High

977577

CWC15
Pre-mRNA-splicing factor CWC15

3

1

High-throughput

0.640

High

985861

SN309
Pre-mRNA-splicing factor SNT309

3

1

High-throughput

0.640

High

996591

CLF1
Pre-mRNA-splicing factor CLF1

3

20

High-throughput

0.640

High

996594

PRP46
Pre-mRNA-splicing factor PRP46

3

8

High-throughput

0.640

High

765089

IF4F1
Eukaryotic initiation factor 4F subunit p150

4

10

Small-scale

0.621

High

485602

SSBP1
Single-stranded nucleic acid-binding protein

1

18

High-throughput

0.618

High

615191

BUR1
Serine/threonine-protein kinase BUR1

1

7

Small-scale

0.618

High

634203

SRO9
RNA-binding protein SRO9

1

20

High-throughput

0.618

High

648449

NSR1
Nuclear localization sequence-binding protein

1

19

High-throughput

0.618

High

704917

LHP1
La protein homolog

1

20

High-throughput

0.618

High

757875

HRB1
Serine/arginine

1

18

High-throughput

0.618

High

775556

SGN1
RNA-binding protein SGN1

1

18

High-throughput

0.618

High

809552

CWC26
Pre-mRNA-splicing factor CWC26

1

1

High-throughput

0.618

High

978109

CTK1
CTD kinase subunit alpha

1

5

Small-scale

0.618

High

985910

MRD1
Multiple RNA-binding domain-containing protein 1

1

18

High-throughput

0.618

High

996582

NCBP2
Nuclear cap-binding protein subunit 2

1

17

High-throughput

0.618

High

141761

THP2
THO complex subunit THP2

3

0

Small-scale

0.613

High

568915

HPR1
THO complex subunit HPR1

3

0

Small-scale

0.613

High

976132

CWC21
Pre-mRNA-splicing factor CWC21

3

0

High-throughput

0.613

High

424930

IF4E
Eukaryotic translation initiation factor 4E

2

1

Small-scale

0.584

High

586448

PRP6
Pre-mRNA-splicing factor 6

2

15

High-throughput

0.584

High

692436

PRP21
Pre-mRNA-splicing factor PRP21

2

2

Small-scale

0.584

High

732402

MUD2
Splicing factor MUD2

2

1

High-throughput

0.584

High

746884

SLT11
Pre-mRNA-splicing factor SLT11

2

2

High-throughput

0.584

High

836945

SF3B1
U2 snRNP component HSH155

2

10

High-throughput

0.584

High

861300

PBP1
PAB1-binding protein 1

2

9

High-throughput

0.584

High

862772

THO2
THO complex subunit 2

2

4

Small-scale

0.584

High

960028

SEN1
Helicase SEN1

2

13

High-throughput

0.584

High

965061

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

6

High-throughput

0.584

High

978483

SYF1
Pre-mRNA-splicing factor SYF1

2

20

High-throughput

0.584

High

687761

BTAF1
TATA-binding protein-associated factor MOT1

1

11

Small-scale

0.561

High

706174

MFT1
THO complex subunit MFT1

2

0

Small-scale

0.559

High

865375

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.559

High

970248

SMD1
Small nuclear ribonucleoprotein Sm D1

2

0

High-throughput

0.559

High

996593

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.559

High

628800

RNA15
mRNA 3'-end-processing protein RNA15

1

18

High-throughput

0.553

High

996589

PUF2
mRNA-binding protein PUF2

1

8

High-throughput

0.553

High

492705

HSP71
Heat shock protein SSA1

2

6

High-throughput

0.552

High

513046

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

598654

ISY1
Pre-mRNA-splicing factor ISY1

2

2

High-throughput

0.533

High

622345

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

2

7

High-throughput

0.533

High

811808

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.493

High

697312

RAD24
Checkpoint protein RAD24

1

0

Small-scale

0.486

High

775588

MPH1
ATP-dependent DNA helicase MPH1

1

17

Small-scale

0.481

High

554251

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

9

High-throughput

0.479

High

577184

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

1

High-throughput

0.479

High

589102

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

4

High-throughput

0.479

High

598585

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

10

Small-scale

0.479

High

603345

SNF2
Transcription regulatory protein SNF2

1

10

High-throughput

0.479

High

605174

XRN1
5'-3' exoribonuclease 1

1

6

High-throughput

0.479

High

624191

DBP2
ATP-dependent RNA helicase DBP2

1

9

High-throughput

0.479

High

628773

RNA14
mRNA 3'-end-processing protein RNA14

1

18

High-throughput

0.479

High

629402

BUD31
Pre-mRNA-splicing factor BUD31

1

1

High-throughput

0.479

High

635937

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.479

High

655765

PRP45
Pre-mRNA-processing protein 45

1

3

High-throughput

0.479

High

663564

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

696176

SWI3
SWI/SNF complex subunit SWI3

1

2

High-throughput

0.479

High

710935

URB1
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.479

High

715246

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.479

High

745555

MAP2
Methionine aminopeptidase 2

1

2

High-throughput

0.479

High

746212

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

20

Small-scale

0.479

High

755875

LSM12
Protein LSM12

1

2

High-throughput

0.479

High

767842

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

2

High-throughput

0.479

High

800692

FIP1
Pre-mRNA polyadenylation factor FIP1

1

6

High-throughput

0.479

High

810941

MTR4
ATP-dependent RNA helicase DOB1

1

20

High-throughput

0.479

High

830830

PRP31
Pre-mRNA-processing factor 31

1

8

High-throughput

0.479

High

861583

CWC22
Pre-mRNA-splicing factor CWC22

1

1

High-throughput

0.479

High

863700

PAP2
Poly(A) RNA polymerase protein 2

1

3

High-throughput

0.479

High

865347

TEX1
Protein TEX1

1

4

High-throughput

0.479

High

873675

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.479

High

976428

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

1

High-throughput

0.479

High

991284

BRE1
E3 ubiquitin-protein ligase BRE1

1

9

High-throughput

0.479

High

994483

REXO4
RNA exonuclease 4

1

3

High-throughput

0.479

High

996586

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.479

High

996587

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

996595

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

996596

NOP56
Nucleolar protein 56

1

8

High-throughput

0.479

High

996603

NOP14
Nucleolar complex protein 14

1

1

High-throughput

0.479

High

996590

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

579821

SNF6
Transcription regulatory protein SNF6

1

0

High-throughput

0.458

High

593096

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

630442

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.458

High

704972

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.458

High

710724

MTR2
mRNA transport regulator MTR2

1

0

Small-scale

0.458

High

747728

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

748094

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

749012

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

755989

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

756806

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

797014

SWP82
SWI/SNF global transcription activator complex subunit SWP82

1

0

High-throughput

0.458

High

805139

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

861080

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

861414

SDA1
Protein SDA1

1

0

High-throughput

0.458

High

865598

SWT21
Protein SWT21

1

0

High-throughput

0.458

High

961607

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

976052

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.458

High

981511

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.458

High

985455

BUR2
Protein BUR2

1

0

Small-scale

0.458

High

987198

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.458

High

994595

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

996585

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.458

High

743725

HMT1
Protein arginine N-methyltransferase 1

1

16

High-throughput

0.457

High

495192

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

769693

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

975986

GCN5
Histone acetyltransferase GCN5

1

9

High-throughput

0.445

High

778707

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.438

High

521068

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.437

High

549524

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.437

High

589462

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

9

High-throughput

0.437

High

593569

DBP3
ATP-dependent RNA helicase DBP3

1

11

High-throughput

0.437

High

593881

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

1

High-throughput

0.437

High

595079

NUP1
Nucleoporin NUP1

1

8

High-throughput

0.437

High

599533

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.437

High

634809

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.437

High

655911

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

1

High-throughput

0.437

High

688727

AAR2
A1 cistron-splicing factor AAR2

1

1

High-throughput

0.437

High

691438

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

3

High-throughput

0.437

High

704442

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

2

High-throughput

0.437

High

762033

DHH1
ATP-dependent RNA helicase DHH1

1

18

High-throughput

0.437

High

778536

PHB1
Prohibitin-1

1

10

High-throughput

0.437

High

856942

CWC23
Pre-mRNA-splicing factor CWC23

1

3

High-throughput

0.437

High

859451

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

8

High-throughput

0.437

High

864626

BRE5
UBP3-associated protein BRE5

1

12

High-throughput

0.437

High

866076

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.437

High

979065

DHR1
Probable ATP-dependent RNA helicase DHR1

1

9

High-throughput

0.437

High

982907

RRP5
rRNA biogenesis protein RRP5

1

11

High-throughput

0.437

High

985435

UTP13
U3 small nucleolar RNA-associated protein 13

1

9

High-throughput

0.437

High

992627

RLP24
Ribosome biogenesis protein RLP24

1

2

High-throughput

0.437

High

996597

AIR2
Protein AIR2

1

6

High-throughput

0.437

High

996598

NOP58
Nucleolar protein 58

1

8

High-throughput

0.437

High

996599

EFG1P
rRNA-processing protein EFG1

1

1

High-throughput

0.437

High

478588

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.407

High

520007

TCPA
T-complex protein 1 subunit alpha

1

1

High-throughput

0.407

High

629069

SCJ1
DnaJ-related protein SCJ1

1

3

High-throughput

0.407

High

760703

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

760975

TCPD
T-complex protein 1 subunit delta

1

2

High-throughput

0.407

High

766257

HSP7E
Heat shock protein SSC3, mitochondrial

1

7

High-throughput

0.407

High

837304

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.407

High

837375

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.407

High

996592

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

977445

NAB6
RNA-binding protein NAB6

2

0

High-throughput

0.328

High

972431

SLU7
Pre-mRNA-splicing factor SLU7

2

0

High-throughput

0.305

High

996601

BRR1
Pre-mRNA-splicing factor BRR1

2

0

High-throughput

0.305

High

500631

TIR1
Cold shock-induced protein TIR1

1

0

Small-scale

0.269

Low

580592

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.249

Low

744816

FAT2
Oxalate--CoA ligase

1

0

High-throughput

0.249

Low

775461

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.249

Low

809680

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.249

Low

974463

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.249

Low

977050

TCB3
Tricalbin-3

1

0

High-throughput

0.249

Low

991544

NOP6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

996600

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.249

Low

996605

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024