Protein: LSM8
U6 snRNA-associated Sm-like protein LSm8

Gene: LSM8
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: P47093

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005688 - U6 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767791

LSM4
U6 snRNA-associated Sm-like protein LSm4

8

20

Small-scale

0.974

High

746309

LSM2
U6 snRNA-associated Sm-like protein LSm2

9

20

Small-scale

0.974

High

811668

LSM6
U6 snRNA-associated Sm-like protein LSm6

8

20

Small-scale

0.970

High

811647

PRP24
U4/U6 snRNA-associated-splicing factor PRP24

8

10

Small-scale

0.967

High

811659

LSM3
U6 snRNA-associated Sm-like protein LSm3

6

20

Small-scale

0.945

High

811655

LSM7
U6 snRNA-associated Sm-like protein LSm7

6

20

Small-scale

0.942

High

768232

LSM5
U6 snRNA-associated Sm-like protein LSm5

5

14

Small-scale

0.924

High

704683

PRP8
Pre-mRNA-splicing factor 8

5

9

Small-scale

0.916

High

795393

SMD3
Small nuclear ribonucleoprotein Sm D3

5

20

Small-scale

0.912

High

811664

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

4

9

Small-scale

0.896

High

731740

SN114
Pre-mRNA-splicing factor SNU114

4

15

Small-scale

0.887

High

766917

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

14

High-throughput

0.881

High

635881

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

3

10

High-throughput

0.835

High

811663

SMD1
Small nuclear ribonucleoprotein Sm D1

3

11

High-throughput

0.830

High

811667

SMD2
Small nuclear ribonucleoprotein Sm D2

3

12

High-throughput

0.830

High

811671

SKI7
Superkiller protein 7

2

3

High-throughput

0.778

High

697225

BRR2
Pre-mRNA-splicing helicase BRR2

10

20

Small-scale

0.750

High

586500

PRP9
Pre-mRNA-splicing factor PRP9

2

6

High-throughput

0.737

High

589085

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

5

15

Small-scale

0.715

High

586420

PRP6
Pre-mRNA-splicing factor 6

4

20

Small-scale

0.687

High

811676

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

8

Small-scale

0.678

High

605081

XRN1
5'-3' exoribonuclease 1

3

4

High-throughput

0.666

High

810515

LSM1
Sm-like protein LSm1

1

18

Small-scale

0.656

High

766462

EDC3
Enhancer of mRNA-decapping protein 3

3

2

High-throughput

0.652

High

811645

MTR3
Exosome complex component MTR3

3

1

High-throughput

0.652

High

811681

HSH49
Protein HSH49

3

9

High-throughput

0.652

High

811646

PRP31
Pre-mRNA-processing factor 31

3

8

Small-scale

0.643

High

612518

NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

0

High-throughput

0.622

High

770313

RUXG
Small nuclear ribonucleoprotein G

1

17

High-throughput

0.618

High

811658

RUXF
Small nuclear ribonucleoprotein F

1

20

High-throughput

0.618

High

811673

RU2A
U2 small nuclear ribonucleoprotein A'

1

10

High-throughput

0.618

High

761129

PCF11
Protein PCF11

2

1

High-throughput

0.603

High

811651

DCP2
m7GpppN-mRNA hydrolase

2

2

High-throughput

0.603

High

754030

PIH1
Protein interacting with Hsp90 1

2

0

High-throughput

0.577

High

754049

NEL1
GTPase-activating protein NEL1

2

0

High-throughput

0.577

High

758954

LYS9
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]

2

0

High-throughput

0.577

High

811649

TOS8
Homeobox protein TOS8

2

0

High-throughput

0.577

High

811652

NOG2
Nucleolar GTP-binding protein 2

2

0

High-throughput

0.577

High

811669

DIB1
Spliceosomal protein DIB1

2

7

High-throughput

0.571

High

811675

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

3

High-throughput

0.571

High

511857

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

636155

NOT1
General negative regulator of transcription subunit 1

1

1

High-throughput

0.541

High

691486

RPN12
26S proteasome regulatory subunit RPN12

1

1

High-throughput

0.536

High

811674

RRP42
Exosome complex component RRP42

1

4

High-throughput

0.536

High

561251

APA1
Protein APA1 [Includes: Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 1

1

0

High-throughput

0.513

High

655860

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.513

High

811679

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

562408

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.508

High

743587

HMT1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.508

High

811116

BBC1
Myosin tail region-interacting protein MTI1

1

3

High-throughput

0.508

High

811654

JJJ1
J protein JJJ1

1

2

High-throughput

0.508

High

811660

SEN1
Helicase SEN1

1

11

High-throughput

0.508

High

811678

DCP1
mRNA-decapping enzyme subunit 1

1

3

High-throughput

0.508

High

785091

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.500

High

811672

RPN8
26S proteasome regulatory subunit RPN8

1

2

High-throughput

0.489

High

440901

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.486

High

594102

KICH
Choline kinase

1

0

High-throughput

0.486

High

733051

ALY1
Arrestin-related trafficking adapter 6

1

0

High-throughput

0.486

High

811653

ATG2
Autophagy-related protein 2

1

0

High-throughput

0.486

High

811666

LIC4
Protein ATC1/LIC4

1

0

High-throughput

0.486

High

811677

DPH6
Diphthine--ammonia ligase

1

0

High-throughput

0.486

High

811662

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.481

High

544013

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

747713

SP381
Pre-mRNA-splicing factor SPP381

1

1

High-throughput

0.479

High

811661

PRP38
Pre-mRNA-splicing factor 38

1

2

High-throughput

0.479

High

811665

CWC21
Pre-mRNA-splicing factor CWC21

1

1

Small-scale

0.479

High

471515

RS28B
Small ribosomal subunit protein eS28B

1

1

High-throughput

0.464

High

540371

BPT1
Bile pigment transporter 1

1

1

High-throughput

0.464

High

746668

TCM62
Mitochondrial chaperone TCM62

1

2

High-throughput

0.464

High

761536

YCFI
Metal resistance protein YCF1

1

1

High-throughput

0.464

High

811650

SCW11
Probable family 17 glucosidase SCW11

1

4

High-throughput

0.464

High

549677

BGL2
Glucan 1,3-beta-glucosidase

1

1

High-throughput

0.457

High

376838

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

6

High-throughput

0.445

High

491696

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

494336

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

628228

SIS1
Protein SIS1

1

3

High-throughput

0.445

High

692315

PRP19
Pre-mRNA-processing factor 19

1

14

Small-scale

0.445

High

695009

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

474287

YK104
Putative uncharacterized protein YKR104W

1

2

High-throughput

0.439

High

811680

RS28A
Small ribosomal subunit protein eS28A

1

1

High-throughput

0.439

High

811656

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

692831

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

579878

COQ1
Hexaprenyl pyrophosphate synthase, mitochondrial

2

0

High-throughput

0.314

High

716068

MTH1
Protein MTH1

2

0

High-throughput

0.314

High

773818

VTH1
VPS10 homolog 1

2

0

High-throughput

0.314

High

811657

YNF0
Uncharacterized protein YNL050C

2

0

High-throughput

0.314

High

424214

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

0

High-throughput

0.279

Low

811648

YGL7
Uncharacterized protein YGL117W

1

0

High-throughput

0.279

Low

577537

ARGD
Acetylornithine aminotransferase, mitochondrial

1

0

High-throughput

0.265

Low

635061

AAD3
Putative aryl-alcohol dehydrogenase AAD3

1

0

High-throughput

0.265

Low

696549

DSS4
Protein DSS4

1

0

High-throughput

0.265

Low

707337

PEX6
Peroxisomal ATPase PEX6

1

0

High-throughput

0.265

Low

766384

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.265

Low

783550

SYS1
Protein SYS1

1

0

High-throughput

0.265

Low

811670

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.265

Low

378366

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

619604

MPCP
Mitochondrial phosphate carrier protein

1

0

High-throughput

0.261

Low

630812

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.261

Low

141789

YL269
Putative uncharacterized protein YLR269C

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024