Protein: SP110
Spindle pole body component 110 (Extragenic suppressor of CMD1-1 mutant protein 1) (Nuclear filament-related protein 1) (Spindle pole body spacer protein SPC110)

Gene: SP110, SPC110
Organism: Saccharomyces cerevisiae S288C
Interactions: 127
UniProt ID: P32380

Gene Ontology (top 5):
GO:0000022 - mitotic spindle elongation
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0005200 - structural constituent of cytoskeleton
GO:0005516 - calmodulin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420248

CALM
Calmodulin

11

4

Small-scale

0.976

High

689250

SPC97
Spindle pole body component SPC97

8

1

Small-scale

0.753

High

689277

TBG
Tubulin gamma chain

8

8

Small-scale

0.752

High

689278

SPC98
Spindle pole body component SPC98

7

1

Small-scale

0.750

High

689222

SP110
Spindle pole body component 110

7

17

Small-scale

0.742

High

416764

CDC31
Cell division control protein 31

1

5

Small-scale

0.724

High

689237

SPC42
Spindle pole body component SPC42

11

0

Small-scale

0.724

High

689281

CNM67
Chaotic nuclear migration protein 67

6

18

Small-scale

0.721

High

689234

SPC29
Spindle pole component 29

8

0

Small-scale

0.719

High

339509

CDK1
Cyclin-dependent kinase 1

5

15

Small-scale

0.718

High

689284

MPS1
Serine/threonine-protein kinase MPS1

3

20

Small-scale

0.664

High

687862

NUD1
Protein NUD1

3

9

Small-scale

0.633

High

689262

MLP2
Protein MLP2

4

18

Small-scale

0.627

High

689285

CDC14
Tyrosine-protein phosphatase CDC14

2

13

Small-scale

0.619

High

490621

HSP71
Heat shock protein SSA1

3

12

Small-scale

0.611

High

510588

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

Small-scale

0.552

High

689288

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.547

High

420017

STE7
Serine/threonine-protein kinase STE7

1

20

High-throughput

0.536

High

689230

SWE1
Mitosis inhibitor protein kinase SWE1

1

20

High-throughput

0.536

High

689246

MSG5
Tyrosine-protein phosphatase MSG5

1

10

High-throughput

0.536

High

689255

MBO1
Gamma tubulin complex adapter SPC72

2

0

Small-scale

0.528

High

689293

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.528

High

689252

SAK1
SNF1-activating kinase 1

1

0

High-throughput

0.513

High

689275

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.513

High

689296

SSK1
Osmolarity two-component system protein SSK1

1

0

High-throughput

0.513

High

689268

STU2
Protein STU2

2

6

Small-scale

0.504

High

675884

XPO1
Exportin-1

1

5

Small-scale

0.481

High

689282

AF9
Protein AF-9 homolog

1

1

High-throughput

0.481

High

689306

GYP5
GTPase-activating protein GYP5

1

2

High-throughput

0.481

High

389061

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

389869

VDAC1
Mitochondrial outer membrane protein porin 1

1

4

High-throughput

0.479

High

440238

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

5

Small-scale

0.479

High

525772

TOP3
DNA topoisomerase 3

1

1

High-throughput

0.479

High

546152

SYKC
Lysine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

661609

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

689225

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

12

Small-scale

0.479

High

689247

RCK2
Serine/threonine-protein kinase RCK2

1

3

High-throughput

0.479

High

689248

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.479

High

689279

PDR16
Phosphatidylinositol transfer protein PDR16

1

2

High-throughput

0.479

High

689283

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

689299

LAM6
Membrane-anchored lipid-binding protein LAM6

1

3

High-throughput

0.479

High

689302

ESA1
Histone acetyltransferase ESA1

1

2

Small-scale

0.479

High

689305

SCC1
Sister chromatid cohesion protein 1

1

2

High-throughput

0.479

High

629696

STE50
Protein STE50

1

0

High-throughput

0.460

High

689231

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

689243

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

689270

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

141835

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.458

High

541531

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.458

High

629237

RBSK
Ribokinase

1

0

High-throughput

0.458

High

689229

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

689256

SS120
Protein SSP120

1

0

High-throughput

0.458

High

689260

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

689264

RTS2
Zinc finger protein RTS2

1

0

High-throughput

0.458

High

689292

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.458

High

689294

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

689295

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.458

High

689301

SGO1
Shugoshin

1

0

High-throughput

0.458

High

689308

SFI1
Protein SFI1

1

0

Small-scale

0.458

High

689309

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

0

High-throughput

0.458

High

689312

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.458

High

356319

H4
Histone H4

1

12

Small-scale

0.445

High

360794

TBB
Tubulin beta chain

1

3

Small-scale

0.445

High

365966

HSP82
ATP-dependent molecular chaperone HSP82

1

12

High-throughput

0.445

High

375315

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.445

High

449957

HSP73
Heat shock protein SSA3

1

12

High-throughput

0.445

High

454235

TBA1
Tubulin alpha-1 chain

1

3

Small-scale

0.445

High

493439

HSP72
Heat shock protein SSA2

1

12

High-throughput

0.445

High

540543

CYPH
Peptidyl-prolyl cis-trans isomerase

1

6

High-throughput

0.445

High

565184

KAR3
Kinesin-like protein KAR3

1

9

Small-scale

0.445

High

615128

BUR1
Serine/threonine-protein kinase BUR1

1

20

Small-scale

0.445

High

633033

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.445

High

643006

BUB2
Mitotic check point protein BUB2

1

3

High-throughput

0.445

High

660038

KIP1
Kinesin-like protein KIP1

1

4

Small-scale

0.445

High

689224

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

4

High-throughput

0.445

High

689233

DOM34
Protein DOM34

1

2

Small-scale

0.445

High

689235

NUF2
Kinetochore protein NUF2

1

13

Small-scale

0.445

High

689242

STU1
Protein STU1

1

3

Small-scale

0.445

High

689251

SET5
Histone-lysine N-methyltransferase SET5

1

3

High-throughput

0.445

High

689257

HSP7E
Heat shock protein SSC3, mitochondrial

1

13

High-throughput

0.445

High

689261

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

689263

NDC80
Kinetochore protein NDC80

1

17

Small-scale

0.445

High

689280

JJJ1
J protein JJJ1

1

9

High-throughput

0.445

High

689289

HOS3
Histone deacetylase HOS3

1

20

High-throughput

0.445

High

689297

BRE1
E3 ubiquitin-protein ligase BRE1

1

17

High-throughput

0.445

High

689311

APC2
Anaphase-promoting complex subunit 2

1

15

Small-scale

0.445

High

526327

SYQ
Glutamine--tRNA ligase

1

2

High-throughput

0.437

High

689226

SNQ2
Protein SNQ2

1

2

High-throughput

0.437

High

689232

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

2

High-throughput

0.437

High

689241

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

2

High-throughput

0.437

High

689253

ATU2
Copper-transporting ATPase

1

3

High-throughput

0.437

High

689266

EMP47
Protein EMP47

1

1

High-throughput

0.437

High

689274

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.437

High

689276

MTM1
Mitochondrial carrier protein MTM1

1

6

High-throughput

0.437

High

689287

KIN4
Serine/threonine-protein kinase KIN4

1

10

Small-scale

0.437

High

689310

EMP46
Protein EMP46

1

4

High-throughput

0.437

High

689223

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

689238

SPC34
DASH complex subunit SPC34

1

0

Small-scale

0.426

High

689244

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

689259

SPC25
Kinetochore protein SPC25

1

0

Small-scale

0.426

High

689291

SPC19
DASH complex subunit SPC19

1

0

Small-scale

0.426

High

689298

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

689307

BBP1
Spindle pole component BBP1

1

0

Small-scale

0.426

High

689236

NIC96
Nucleoporin NIC96

1

1

Small-scale

0.407

High

689249

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

2

Small-scale

0.407

High

689258

BIM1
Protein BIM1

1

5

Small-scale

0.407

High

689304

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.279

Low

689269

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

420047

TYSY
Thymidylate synthase

1

0

High-throughput

0.249

Low

597933

ATP5E
ATP synthase subunit epsilon, mitochondrial

1

0

High-throughput

0.249

Low

604312

ATP12
Protein ATP12, mitochondrial

1

0

High-throughput

0.249

Low

689228

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

689239

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

689240

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

689245

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

689265

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

High-throughput

0.249

Low

689273

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

689286

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.249

Low

689290

YMC0
Uncharacterized protein YML020W

1

0

High-throughput

0.249

Low

689300

ENB1
Siderophore iron transporter ENB1

1

0

High-throughput

0.249

Low

689303

TIM18
Mitochondrial import inner membrane translocase subunit TIM18

1

0

High-throughput

0.249

Low

689227

CDC13
Cell division control protein 13

1

0

Small-scale

0.232

Low

689254

PO152
Nucleoporin POM152

1

0

Small-scale

0.232

Low

689267

NUP85
Nucleoporin NUP85

1

0

Small-scale

0.232

Low

689271

SP105
Spindle pole body component SPC105

1

0

Small-scale

0.232

Low

689272

MPS2
Monopolar spindle protein 2

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024