Protein: ECM29
Proteasome component ECM29 (Extracellular mutant protein 29)

Gene: ECM29
Organism: Saccharomyces cerevisiae S288C
Interactions: 209
UniProt ID: P38737

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0036503 - ERAD pathway
GO:0043248 - proteasome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

753415

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

7

10

Small-scale

0.742

High

619463

PSA2
Proteasome subunit alpha type-2

5

9

High-throughput

0.712

High

753453

RPN5
26S proteasome regulatory subunit RPN5

5

3

Small-scale

0.712

High

703608

PRS6A
26S proteasome regulatory subunit 6A

5

9

Small-scale

0.711

High

703893

PRS7
26S proteasome regulatory subunit 7 homolog

4

9

High-throughput

0.691

High

753398

RPN3
26S proteasome regulatory subunit RPN3

4

1

High-throughput

0.691

High

753446

RPN8
26S proteasome regulatory subunit RPN8

4

2

High-throughput

0.691

High

753455

RPN6
26S proteasome regulatory subunit RPN6

4

2

High-throughput

0.691

High

753416

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

4

8

Small-scale

0.687

High

753403

PSA4
Proteasome subunit alpha type-4

4

10

Small-scale

0.686

High

691466

RPN12
26S proteasome regulatory subunit RPN12

3

1

High-throughput

0.662

High

753386

RPN10
26S proteasome regulatory subunit RPN10

3

2

High-throughput

0.662

High

693296

RPN2
26S proteasome regulatory subunit RPN2

3

5

High-throughput

0.656

High

703794

PRS6B
26S proteasome regulatory subunit 6B homolog

3

6

High-throughput

0.656

High

751158

PSB1
Proteasome subunit beta type-1

3

11

High-throughput

0.656

High

753383

RPN1
26S proteasome regulatory subunit RPN1

3

5

High-throughput

0.656

High

753404

PRS4
26S proteasome regulatory subunit 4 homolog

3

7

High-throughput

0.656

High

753427

PRS10
26S proteasome subunit RPT4

3

9

High-throughput

0.656

High

753435

PRS8
26S proteasome regulatory subunit 8 homolog

3

9

High-throughput

0.656

High

753439

RPN9
26S proteasome regulatory subunit RPN9

3

1

High-throughput

0.656

High

753441

RPN7
26S proteasome regulatory subunit RPN7

3

3

High-throughput

0.656

High

697079

RAD23
UV excision repair protein RAD23

3

7

High-throughput

0.643

High

604793

PSB4
Proteasome subunit beta type-4

3

9

Small-scale

0.640

High

366241

HSP82
ATP-dependent molecular chaperone HSP82

3

9

High-throughput

0.633

High

680679

HS104
Heat shock protein 104

3

4

High-throughput

0.633

High

675414

PSB5
Proteasome subunit beta type-5

3

11

Small-scale

0.624

High

746493

IMB2
Importin subunit beta-2

2

12

High-throughput

0.621

High

511190

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.601

High

753393

RV167
Reduced viability upon starvation protein 167

2

1

High-throughput

0.601

High

420493

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

2

1

High-throughput

0.588

High

519587

ERF1
Eukaryotic peptide chain release factor subunit 1

2

1

High-throughput

0.588

High

141847

RPN13
26S proteasome regulatory subunit RPN13

2

0

High-throughput

0.585

High

407027

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.584

High

407895

RS13
Small ribosomal subunit protein uS15

2

3

High-throughput

0.584

High

543679

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

597232

PSA7
Probable proteasome subunit alpha type-7

2

9

High-throughput

0.584

High

597316

PSA1
Proteasome subunit alpha type-1

2

8

High-throughput

0.584

High

619356

PSA3
Proteasome subunit alpha type-3

2

9

High-throughput

0.584

High

619970

PSB6
Proteasome subunit beta type-6

2

12

High-throughput

0.584

High

689177

PSA5
Proteasome subunit alpha type-5

2

8

High-throughput

0.584

High

753402

PSA6
Proteasome subunit alpha type-6

2

9

High-throughput

0.584

High

694630

HSP7F
Heat shock protein homolog SSE1

2

16

High-throughput

0.571

High

753430

APJ1
J domain-containing protein APJ1

2

6

High-throughput

0.571

High

753414

BLM10
Proteasome activator BLM10

2

0

High-throughput

0.559

High

493882

HSP72
Heat shock protein SSA2

2

13

High-throughput

0.552

High

704625

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

2

4

High-throughput

0.537

High

753429

NAT10
RNA cytidine acetyltransferase

2

2

High-throughput

0.537

High

429697

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

2

High-throughput

0.536

High

710507

PP2C3
Protein phosphatase 2C homolog 3

1

4

High-throughput

0.536

High

752821

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

753444

RBX1
RING-box protein HRT1

1

6

High-throughput

0.536

High

753456

AHA1
Hsp90 co-chaperone AHA1

1

2

High-throughput

0.536

High

358048

RS17A
Small ribosomal subunit protein eS17A

2

2

High-throughput

0.533

High

425932

RS19A
Small ribosomal subunit protein eS19A

2

2

High-throughput

0.533

High

619571

MPCP
Mitochondrial phosphate carrier protein

1

8

High-throughput

0.489

High

730973

MAOM
NAD-dependent malic enzyme, mitochondrial

1

2

High-throughput

0.489

High

523378

SRS2
ATP-dependent DNA helicase SRS2

1

3

Small-scale

0.481

High

753406

PRK1
Actin-regulating kinase PRK1

1

0

Small-scale

0.480

High

333778

ADH1
Alcohol dehydrogenase 1

1

2

High-throughput

0.479

High

334676

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.479

High

340127

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.479

High

360869

TBB
Tubulin beta chain

1

7

High-throughput

0.479

High

368025

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.479

High

399451

RLA0
Large ribosomal subunit protein uL10

1

4

High-throughput

0.479

High

404569

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.479

High

405179

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

410990

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.479

High

421631

FAS1
Fatty acid synthase subunit beta

1

1

High-throughput

0.479

High

424501

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.479

High

446154

MYO1
Myosin-1

1

2

High-throughput

0.479

High

478165

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.479

High

479736

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

482246

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

485722

IF4A
ATP-dependent RNA helicase eIF4A

1

12

High-throughput

0.479

High

491113

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.479

High

498913

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.479

High

524288

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

534975

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

556027

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.479

High

558041

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

604551

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

3

High-throughput

0.479

High

607267

RFA1
Replication factor A protein 1

1

9

High-throughput

0.479

High

608693

UBA1
Ubiquitin-activating enzyme E1 1

1

1

High-throughput

0.479

High

625930

PSB2
Proteasome subunit beta type-2

1

8

High-throughput

0.479

High

631857

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.479

High

632485

PSB3
Proteasome subunit beta type-3

1

8

High-throughput

0.479

High

636614

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

640932

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

644881

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.479

High

662135

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

675463

PSB7
Proteasome subunit beta type-7

1

11

High-throughput

0.479

High

688224

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

692224

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

4

High-throughput

0.479

High

710374

EDE1
EH domain-containing and endocytosis protein 1

1

3

High-throughput

0.479

High

729894

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

742775

GBLP
Small ribosomal subunit protein RACK1

1

11

High-throughput

0.479

High

746824

TRM7
tRNA

1

2

High-throughput

0.479

High

752431

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

753389

END3
Actin cytoskeleton-regulatory complex protein END3

1

3

High-throughput

0.479

High

753394

SNF7
Vacuolar-sorting protein SNF7

1

6

High-throughput

0.479

High

753410

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.479

High

753413

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.479

High

753423

RPN14
26S proteasome regulatory subunit RPN14

1

12

High-throughput

0.479

High

753424

CDH1
APC/C activator protein CDH1

1

14

Small-scale

0.479

High

753428

CAF40
Protein CAF40

1

1

High-throughput

0.479

High

753431

ACT
Actin

1

6

High-throughput

0.479

High

753432

H3
Histone H3

1

6

High-throughput

0.479

High

753434

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

753438

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.479

High

753445

MCA1
Metacaspase-1

1

1

High-throughput

0.479

High

753448

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

753451

SGT2
Small glutamine-rich tetratricopeptide repeat-containing protein 2

1

8

High-throughput

0.479

High

753452

RIO1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.479

High

294119

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.458

High

340668

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.458

High

341713

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.458

High

429571

LYS2
L-2-aminoadipate reductase

1

0

High-throughput

0.458

High

551363

ABP1
Actin-binding protein

1

0

High-throughput

0.458

High

566172

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

713690

NOT4
General negative regulator of transcription subunit 4

1

0

High-throughput

0.458

High

731543

POC2
Proteasome assembly chaperone 2

1

0

High-throughput

0.458

High

747925

UMP1
Proteasome maturation factor UMP1

1

0

High-throughput

0.458

High

753385

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

753421

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

High-throughput

0.458

High

753442

VPS74
Vacuolar protein sorting-associated protein 74

1

0

High-throughput

0.458

High

753443

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.458

High

753449

RCN2
Regulator of calcineurin 2

1

0

High-throughput

0.458

High

753450

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

450034

HSP73
Heat shock protein SSA3

1

13

High-throughput

0.445

High

612229

HSP12
12 kDa heat shock protein

1

1

High-throughput

0.445

High

628016

SIS1
Protein SIS1

1

4

High-throughput

0.445

High

633199

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

705133

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

715792

MDJ1
DnaJ homolog 1, mitochondrial

1

9

High-throughput

0.445

High

753384

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

753391

XDJ1
DnaJ protein homolog XDJ1

1

6

High-throughput

0.445

High

753392

FHP
Flavohemoprotein

1

3

High-throughput

0.445

High

753396

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

753400

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

753419

HLJ1
Protein HLJ1

1

3

High-throughput

0.445

High

342921

ENO2
Enolase 2

1

2

High-throughput

0.437

High

383124

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.437

High

393564

PMA1
Plasma membrane ATPase 1

1

5

High-throughput

0.437

High

405008

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

405989

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.437

High

406129

RL36A
Large ribosomal subunit protein eL36A

1

1

High-throughput

0.437

High

406331

RL15A
Large ribosomal subunit protein eL15A

1

3

High-throughput

0.437

High

406522

RL22A
Large ribosomal subunit protein eL22A

1

2

High-throughput

0.437

High

407516

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.437

High

413487

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

471770

RL27A
Large ribosomal subunit protein eL27A

1

3

High-throughput

0.437

High

472172

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

478886

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.437

High

479101

RL43B
Large ribosomal subunit protein eL43B

1

1

High-throughput

0.437

High

479466

RS24A
Small ribosomal subunit protein eS24A

1

3

High-throughput

0.437

High

480084

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

480652

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

481329

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.437

High

481505

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.437

High

481632

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.437

High

481908

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.437

High

482710

RL19B
Large ribosomal subunit protein eL19

1

3

High-throughput

0.437

High

482864

RL35A
Large ribosomal subunit protein uL29A

1

3

High-throughput

0.437

High

546729

SEC23
Protein transport protein SEC23

1

3

High-throughput

0.437

High

560967

EF3A
Elongation factor 3A

1

3

High-throughput

0.437

High

564279

RL8A
Large ribosomal subunit protein eL8A

1

4

High-throughput

0.437

High

578532

SEC18
Vesicular-fusion protein SEC18

1

4

High-throughput

0.437

High

580547

FAS2
Fatty acid synthase subunit alpha

1

1

High-throughput

0.437

High

604402

CLH
Clathrin heavy chain

1

3

High-throughput

0.437

High

613689

RS3A2
Small ribosomal subunit protein eS1B

1

4

High-throughput

0.437

High

645202

RL16B
Large ribosomal subunit protein uL13B

1

3

High-throughput

0.437

High

645424

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

685519

COPG
Coatomer subunit gamma

1

2

High-throughput

0.437

High

687371

EF2
Elongation factor 2

1

6

High-throughput

0.437

High

689337

ARP2
Actin-related protein 2

1

6

High-throughput

0.437

High

700390

RSSA1
Small ribosomal subunit protein uS2A

1

7

High-throughput

0.437

High

706253

RS3A1
Small ribosomal subunit protein eS1A

1

4

High-throughput

0.437

High

732708

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.437

High

745639

NU170
Nucleoporin NUP170

1

4

High-throughput

0.437

High

753382

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

4

High-throughput

0.437

High

753388

SEC31
Protein transport protein SEC31

1

7

High-throughput

0.437

High

753395

RS26A
Small ribosomal subunit protein eS26A

1

1

High-throughput

0.437

High

753401

RL13B
Large ribosomal subunit protein eL13B

1

2

High-throughput

0.437

High

753405

SEC24
Protein transport protein SEC24

1

3

High-throughput

0.437

High

753407

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.437

High

753411

COPB
Coatomer subunit beta

1

1

High-throughput

0.437

High

753412

COPB2
Coatomer subunit beta'

1

4

High-throughput

0.437

High

753418

RS7B
Small ribosomal subunit protein eS7B

1

2

High-throughput

0.437

High

753425

RL26B
Large ribosomal subunit protein uL24B

1

4

High-throughput

0.437

High

753433

ACAC
Acetyl-CoA carboxylase

1

2

High-throughput

0.437

High

753436

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.437

High

753437

ESC1
Silent chromatin protein ESC1

1

1

High-throughput

0.437

High

753447

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

753397

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

753417

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

753420

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

753454

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

541702

SEC63
Protein translocation protein SEC63

1

5

High-throughput

0.407

High

753399

PIC2
Mitochondrial phosphate carrier protein 2

1

5

High-throughput

0.407

High

753408

DJP1
DnaJ-like protein 1

1

4

High-throughput

0.407

High

753422

PHB2
Prohibitin-2

1

8

High-throughput

0.407

High

753409

LCB2
Serine palmitoyltransferase 2

2

0

High-throughput

0.324

High

450306

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

636223

FUB1
Silencing boundary-establishment protein FUB1

1

0

High-throughput

0.249

Low

687094

VPS10
Vacuolar protein sorting/targeting protein VPS10

1

0

High-throughput

0.249

Low

753387

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

753426

SHY1
Cytochrome oxidase assembly protein SHY1

1

0

Small-scale

0.249

Low

753440

RTN1
Reticulon-like protein 1

1

0

High-throughput

0.249

Low

753390

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024