Protein: ERB1
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)

Gene: ERB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 223
UniProt ID: Q04660

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

860879

PESC
Pescadillo homolog

20

4

Small-scale

0.989

High

980177

YTM1
Ribosome biogenesis protein YTM1

13

18

Small-scale

0.985

High

976852

HAS1
ATP-dependent RNA helicase HAS1

8

19

High-throughput

0.967

High

638853

SPB4
ATP-dependent rRNA helicase SPB4

7

17

High-throughput

0.960

High

594068

MAK11
Protein MAK11

3

16

Small-scale

0.847

High

691419

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

3

7

High-throughput

0.839

High

980149

ERB1
Ribosome biogenesis protein ERB1

2

16

High-throughput

0.776

High

859506

NSA1
Ribosome biogenesis protein NSA1

9

3

Small-scale

0.751

High

764240

NOC2
Nucleolar complex protein 2

7

1

Small-scale

0.750

High

766699

NUG1
Nuclear GTP-binding protein NUG1

9

11

Small-scale

0.750

High

766595

NOP16
Nucleolar protein 16

2

0

High-throughput

0.748

High

733932

RPF2
Ribosome biogenesis protein RPF2

8

2

Small-scale

0.747

High

776509

RLP7
Ribosome biogenesis protein RLP7

7

7

Small-scale

0.747

High

973455

NOG1
Nucleolar GTP-binding protein 1

7

7

Small-scale

0.745

High

634447

SPB1
27S pre-rRNA

2

8

High-throughput

0.737

High

778857

NOP2
25S rRNA

6

4

Small-scale

0.732

High

754188

CIC1
Proteasome-interacting protein CIC1

6

4

Small-scale

0.729

High

864684

NOG2
Nucleolar GTP-binding protein 2

6

11

Small-scale

0.723

High

754908

SSF1
Ribosome biogenesis protein SSF1

6

2

Small-scale

0.722

High

980185

IF6
Eukaryotic translation initiation factor 6

5

1

Small-scale

0.718

High

866262

NOP15
Ribosome biogenesis protein 15

5

10

High-throughput

0.716

High

980181

MAK21
Ribosome biogenesis protein MAK21

5

6

High-throughput

0.712

High

699727

DRS1
ATP-dependent RNA helicase DRS1

4

18

High-throughput

0.699

High

980169

BRX1
Ribosome biogenesis protein BRX1

4

9

High-throughput

0.697

High

744691

TAF5
Transcription initiation factor TFIID subunit 5

1

18

High-throughput

0.691

High

965037

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

12

High-throughput

0.691

High

975963

GCN5
Histone acetyltransferase GCN5

1

17

High-throughput

0.691

High

979233

UTP15
U3 small nucleolar RNA-associated protein 15

1

17

High-throughput

0.691

High

742064

NOP4
Nucleolar protein 4

4

6

High-throughput

0.691

High

768046

NSA2
Ribosome biogenesis protein NSA2

4

3

Small-scale

0.691

High

978432

RRP17
Ribosomal RNA-processing protein 17

4

1

High-throughput

0.686

High

980183

DBP10
ATP-dependent RNA helicase DBP10

4

14

High-throughput

0.680

High

410178

EIF3B
Eukaryotic translation initiation factor 3 subunit B

2

2

High-throughput

0.679

High

980157

FKBP4
FK506-binding protein 4

3

7

High-throughput

0.667

High

744241

MAK5
ATP-dependent RNA helicase MAK5

3

19

High-throughput

0.662

High

703114

MRT4
Ribosome assembly factor MRT4

3

6

Small-scale

0.656

High

980151

RRP5
rRNA biogenesis protein RRP5

3

9

High-throughput

0.656

High

731863

EBP2
rRNA-processing protein EBP2

3

2

Small-scale

0.650

High

979444

PUF6
Pumilio homology domain family member 6

3

2

Small-scale

0.650

High

710922

URB1
Nucleolar pre-ribosomal-associated protein 1

3

0

Small-scale

0.642

High

756867

RIX1
Pre-rRNA-processing protein RIX1

3

1

Small-scale

0.640

High

980184

NOP58
Nucleolar protein 58

3

6

High-throughput

0.633

High

625843

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.631

High

696401

PP12
Serine/threonine-protein phosphatase PP1-2

2

6

High-throughput

0.628

High

859427

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

8

High-throughput

0.628

High

797394

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.622

High

630890

NLE1
Ribosome assembly protein 4

1

17

Small-scale

0.618

High

733158

DBP7
ATP-dependent RNA helicase DBP7

1

15

Small-scale

0.618

High

742991

GBLP
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

810914

MTR4
ATP-dependent RNA helicase DOB1

1

12

Small-scale

0.618

High

841433

UBC9
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.618

High

535114

RL3
Large ribosomal subunit protein uL3

2

6

High-throughput

0.611

High

865755

NOP13
Nucleolar protein 13

2

8

High-throughput

0.611

High

980165

NOC3
Nucleolar complex-associated protein 3

2

3

High-throughput

0.611

High

427388

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

1

1

High-throughput

0.595

High

715484

RRP1
Ribosomal RNA-processing protein 1

2

6

Small-scale

0.584

High

748697

ENP1
Essential nuclear protein 1

2

1

High-throughput

0.584

High

792572

UTP10
U3 small nucleolar RNA-associated protein 10

2

3

High-throughput

0.584

High

980166

RLP24
Ribosome biogenesis protein RLP24

2

3

Small-scale

0.584

High

980152

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.575

High

628453

SIS1
Protein SIS1

2

10

High-throughput

0.571

High

704419

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

3

High-throughput

0.571

High

755329

RPF1
Ribosome production factor 1

2

1

High-throughput

0.571

High

358257

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.553

High

820168

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.553

High

860373

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.553

High

492385

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.552

High

769430

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

866147

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

Small-scale

0.551

High

416249

SIR2
NAD-dependent histone deacetylase SIR2

1

7

High-throughput

0.536

High

499073

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.536

High

512672

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.536

High

550118

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.536

High

584794

CSK22
Casein kinase II subunit alpha'

1

17

High-throughput

0.536

High

633896

SGF29
SAGA-associated factor 29

1

2

High-throughput

0.536

High

676362

XPO1
Exportin-1

1

11

High-throughput

0.536

High

715389

SPT7
Transcriptional activator SPT7

1

15

High-throughput

0.536

High

756713

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.536

High

760589

SSN3
Meiotic mRNA stability protein kinase SSN3

1

10

High-throughput

0.536

High

961487

CDC14
Tyrosine-protein phosphatase CDC14

1

7

High-throughput

0.536

High

970194

PVH1
Tyrosine-protein phosphatase YVH1

1

2

High-throughput

0.536

High

974186

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

10

High-throughput

0.536

High

811458

TCPQ
T-complex protein 1 subunit theta

2

20

High-throughput

0.533

High

980182

HSP42
Heat shock protein 42

2

2

High-throughput

0.533

High

549491

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

High-throughput

0.515

High

976587

STE20
Serine/threonine-protein kinase STE20

1

15

High-throughput

0.515

High

865464

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

978588

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

980164

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

478509

HSP77
Import motor subunit, mitochondrial

2

12

High-throughput

0.504

High

614799

KC11
Casein kinase I homolog 1

1

7

High-throughput

0.501

High

701925

SWE1
Mitosis inhibitor protein kinase SWE1

1

8

High-throughput

0.501

High

554741

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

560793

BIP
Endoplasmic reticulum chaperone BiP

1

9

High-throughput

0.500

High

636743

CDC48
Cell division control protein 48

1

4

High-throughput

0.500

High

703851

PRS6B
26S proteasome regulatory subunit 6B homolog

1

6

High-throughput

0.500

High

980187

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.493

High

584191

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.489

High

753248

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

1

High-throughput

0.489

High

761076

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

765568

SAHH
Adenosylhomocysteinase

1

3

High-throughput

0.489

High

767973

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

High-throughput

0.489

High

804906

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.489

High

812405

YMR1
Phosphoinositide 3-phosphatase

1

3

High-throughput

0.489

High

817350

ASK10
Activator of SKN7 protein 10

1

1

High-throughput

0.489

High

864606

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.489

High

968055

KIN4
Serine/threonine-protein kinase KIN4

1

6

High-throughput

0.489

High

975913

PKH3
Serine/threonine-protein kinase PKH3

1

5

High-throughput

0.489

High

980154

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

13

High-throughput

0.489

High

980155

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.489

High

980171

HRK1
Serine/threonine-protein kinase HRK1

1

4

High-throughput

0.489

High

980179

RTK1
Probable serine/threonine-protein kinase RTK1

1

5

High-throughput

0.489

High

141521

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

383349

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

392565

H2A2
Histone H2A.2

1

7

High-throughput

0.479

High

405825

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.479

High

407313

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

408123

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

408460

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

5

High-throughput

0.479

High

413704

RS14A
Small ribosomal subunit protein uS11A

1

4

High-throughput

0.479

High

480310

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

501247

MAK16
Protein MAK16

1

2

High-throughput

0.479

High

604615

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.479

High

632088

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

634763

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

645645

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

663272

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

665043

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

733679

LAS1
Protein LAS1

1

1

Small-scale

0.479

High

744990

PPS1
Dual specificity protein phosphatase PPS1

1

2

High-throughput

0.479

High

746266

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

757342

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

9

High-throughput

0.479

High

772332

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.479

High

775255

ULP2
Ubiquitin-like-specific protease 2

1

5

High-throughput

0.479

High

811349

NOP9
Nucleolar protein 9

1

1

Small-scale

0.479

High

861406

SDA1
Protein SDA1

1

2

High-throughput

0.479

High

861620

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.479

High

864544

TR112
Multifunctional methyltransferase subunit TRM112

1

1

Small-scale

0.479

High

866460

APJ1
J domain-containing protein APJ1

1

12

High-throughput

0.479

High

866860

RCM1
25S rRNA

1

4

High-throughput

0.479

High

872805

ORC1
Origin recognition complex subunit 1

1

3

High-throughput

0.479

High

972631

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.479

High

975822

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.479

High

979015

DHR1
Probable ATP-dependent RNA helicase DHR1

1

9

High-throughput

0.479

High

979708

UTP14
U3 small nucleolar RNA-associated protein 14

1

11

High-throughput

0.479

High

980150

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.479

High

980153

HRQ1
ATP-dependent helicase HRQ1

1

15

Small-scale

0.479

High

980156

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

980158

JIP5
WD repeat-containing protein JIP5

1

18

High-throughput

0.479

High

980159

DBP9
ATP-dependent RNA helicase DBP9

1

10

High-throughput

0.479

High

980162

NOC4
Nucleolar complex protein 4

1

6

High-throughput

0.479

High

980168

NOP12
Nucleolar protein 12

1

11

High-throughput

0.479

High

980173

RRS1
Regulator of ribosome biosynthesis

1

2

High-throughput

0.479

High

980174

NIP7
60S ribosome subunit biogenesis protein NIP7

1

1

High-throughput

0.479

High

980176

MDN1
Midasin

1

18

High-throughput

0.479

High

980178

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.479

High

980180

SSF2
Ribosome biogenesis protein SSF2

1

2

High-throughput

0.479

High

980186

H2AZ
Histone H2A.Z

1

6

High-throughput

0.479

High

692922

SPT16
FACT complex subunit SPT16

1

4

High-throughput

0.470

High

411088

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

688421

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

732245

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

775855

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

811795

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

977851

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

980160

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

980161

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

980170

SGO1
Shugoshin

1

0

High-throughput

0.458

High

859118

ATG1
Serine/threonine-protein kinase ATG1

1

7

High-throughput

0.457

High

334986

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.457

High

342109

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.457

High

342776

ENO1
Enolase 1

1

3

High-throughput

0.457

High

378399

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

381721

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.457

High

521056

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

588221

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.457

High

494921

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

695490

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

746343

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

9

High-throughput

0.445

High

754692

SSZ1
Ribosome-associated complex subunit SSZ1

1

8

High-throughput

0.445

High

761305

CAJ1
Protein CAJ1

1

12

High-throughput

0.445

High

810399

JJJ2
J protein JJJ2

1

9

High-throughput

0.445

High

426144

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

471249

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472389

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

478984

RL20B
Large ribosomal subunit protein eL20B

1

2

High-throughput

0.437

High

480877

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.437

High

482457

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

628683

CANB
Calcineurin subunit B

1

3

High-throughput

0.437

High

700620

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

706486

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

730110

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

752665

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

762542

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

959869

NUM1
Nuclear migration protein NUM1

1

14

High-throughput

0.437

High

967754

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

980172

RS10A
Small ribosomal subunit protein eS10A

1

5

High-throughput

0.437

High

757467

SPT8
Transcription factor SPT8

1

0

High-throughput

0.426

High

758395

SNF11
Transcription regulatory protein SNF11

1

0

High-throughput

0.426

High

792362

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.426

High

368394

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

544388

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.407

High

629044

SCJ1
DnaJ-related protein SCJ1

1

9

High-throughput

0.407

High

705634

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

773752

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.407

High

404373

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.279

Low

426404

PMM
Phosphomannomutase

1

0

High-throughput

0.279

Low

620624

EXG1
Glucan 1,3-beta-glucosidase I/II

1

0

High-throughput

0.279

Low

759039

HXT7
High-affinity hexose transporter HXT7

1

0

High-throughput

0.279

Low

860007

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.279

Low

975222

MUB1
MYND-type zinc finger protein MUB1

1

0

High-throughput

0.279

Low

980167

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.279

Low

980175

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

0

High-throughput

0.279

Low

756101

YHT8
Uncharacterized protein YHR138C

1

0

High-throughput

0.269

Low

648241

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

977557

ENT5
Epsin-5

1

0

Small-scale

0.261

Low

343689

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

537482

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

570723

HXKG
Glucokinase-1

1

0

High-throughput

0.261

Low

701080

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

758020

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

980163

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024