Protein: DUN1
DNA damage response protein kinase DUN1 (EC 2.7.11.1)

Gene: DUN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 94
UniProt ID: P39009

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

606007

RAD53
Serine/threonine-protein kinase RAD53

8

19

Small-scale

0.969

High

759137

SML1
Ribonucleotide reductase inhibitor protein SML1

7

1

Small-scale

0.751

High

759131

CDC14
Tyrosine-protein phosphatase CDC14

1

7

High-throughput

0.691

High

759147

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

6

High-throughput

0.691

High

614651

KC11
Casein kinase I homolog 1

1

18

High-throughput

0.656

High

439655

SPS1
Sporulation-specific protein 1

1

17

High-throughput

0.647

High

649892

CDC15
Cell division control protein 15

1

17

High-throughput

0.647

High

752116

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.646

High

759130

ACT
Actin

1

6

High-throughput

0.646

High

412752

KAPA
cAMP-dependent protein kinase type 1

1

13

Small-scale

0.618

High

336680

SODC
Superoxide dismutase [Cu-Zn]

2

0

Small-scale

0.612

High

732620

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

0

Small-scale

0.589

High

511329

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.584

High

759111

AKR1
Palmitoyltransferase AKR1

1

2

High-throughput

0.579

High

366293

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.575

High

692455

KAR9
Karyogamy protein KAR9

2

0

High-throughput

0.565

High

743538

HMT1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.541

High

419548

RAD1
DNA repair protein RAD1

1

1

High-throughput

0.536

High

420125

TOP2
DNA topoisomerase 2

1

1

High-throughput

0.536

High

424864

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.536

High

521131

RAD50
DNA repair protein RAD50

1

16

High-throughput

0.536

High

539926

RAD9
DNA repair protein RAD9

1

1

High-throughput

0.536

High

540581

CYPH
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.536

High

640315

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

1

High-throughput

0.536

High

697292

RAD24
Checkpoint protein RAD24

1

1

High-throughput

0.536

High

759112

RSP5
E3 ubiquitin-protein ligase RSP5

1

12

High-throughput

0.536

High

759141

RAD28
Radiation-sensitive protein 28

1

14

High-throughput

0.536

High

759122

COM1
DNA endonuclease SAE2

1

1

Small-scale

0.527

High

759126

CWC23
Pre-mRNA-splicing factor CWC23

1

8

High-throughput

0.514

High

759129

JJJ1
J protein JJJ1

1

9

High-throughput

0.514

High

523385

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.513

High

531679

DHAS
Aspartate-semialdehyde dehydrogenase

1

0

High-throughput

0.513

High

657733

YJU2
Splicing factor YJU2

1

0

High-throughput

0.513

High

759138

YM71
NADP-dependent 3-hydroxy acid dehydrogenase

1

0

High-throughput

0.513

High

744118

ATM
Serine/threonine-protein kinase TEL1

1

20

Small-scale

0.501

High

744136

ATR
Serine/threonine-protein kinase MEC1

1

20

Small-scale

0.501

High

759114

VHR2
Transcription factor VHR2

1

1

High-throughput

0.501

High

759119

TCPH
T-complex protein 1 subunit eta

1

17

High-throughput

0.501

High

389283

HXKA
Hexokinase-1

1

5

High-throughput

0.500

High

389391

HXKB
Hexokinase-2

1

5

High-throughput

0.500

High

554646

HSP26
Heat shock protein 26

1

1

High-throughput

0.500

High

588082

HSP60
Heat shock protein 60, mitochondrial

1

9

High-throughput

0.500

High

759132

OYE2
NADPH dehydrogenase 2

1

1

High-throughput

0.500

High

715682

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.493

High

629898

YCP4
Flavoprotein-like protein YCP4

1

2

High-throughput

0.489

High

715891

ATG19
Autophagy-related protein 19

1

1

High-throughput

0.489

High

739487

PGM2
Phosphoglucomutase 2

1

1

High-throughput

0.489

High

743767

PDX3
Pyridoxamine 5'-phosphate oxidase

1

1

High-throughput

0.489

High

759120

AGX1
Alanine--glyoxylate aminotransferase 1

1

3

High-throughput

0.489

High

759123

NET1
Nucleolar protein NET1

1

2

High-throughput

0.489

High

759128

YG3A
Uncharacterized protein YGR130C

1

15

High-throughput

0.489

High

759139

EIS1
Eisosome protein 1

1

8

High-throughput

0.489

High

759143

PST2
Protoplast secreted protein 2

1

2

High-throughput

0.489

High

759144

AHA1
Hsp90 co-chaperone AHA1

1

2

High-throughput

0.489

High

141899

DIF1
Damage-regulated import facilitator 1

1

0

Small-scale

0.480

High

501289

PCKA
Phosphoenolpyruvate carboxykinase

1

0

High-throughput

0.480

High

756479

ADY1
Prospore formation at selected spindle poles protein 1

1

0

High-throughput

0.480

High

759115

YEQ9
Uncharacterized protein YER079W

1

0

High-throughput

0.480

High

759118

CUP9
Homeobox protein CUP9

1

0

High-throughput

0.480

High

759121

CHA4
Activatory protein CHA4

1

0

High-throughput

0.480

High

759124

YJ26
Uncharacterized protein YJR056C

1

0

High-throughput

0.480

High

759135

PANK
Pantothenate kinase CAB1

1

0

High-throughput

0.480

High

410999

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.479

High

558059

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

653065

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.458

High

662235

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

759133

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

759142

HSP42
Heat shock protein 42

1

1

High-throughput

0.457

High

759145

YG12A
Transposon Ty1-GR2 Gag polyprotein

1

3

High-throughput

0.457

High

525778

TOP3
DNA topoisomerase 3

1

1

High-throughput

0.457

High

732609

TCD2
tRNA threonylcarbamoyladenosine dehydratase 2

1

1

Small-scale

0.457

High

360879

TBB
Tubulin beta chain

1

11

High-throughput

0.457

High

378346

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.457

High

540094

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.457

High

759117

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.457

High

478197

HSP77
Import motor subunit, mitochondrial

1

16

High-throughput

0.445

High

491239

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

705181

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.445

High

759116

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

744730

KTR3
Probable mannosyltransferase KTR3

1

0

High-throughput

0.438

High

759146

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.438

High

592903

SRP54
Signal recognition particle subunit SRP54

1

1

High-throughput

0.407

High

486139

ADH4
Alcohol dehydrogenase 4

1

0

High-throughput

0.279

Low

605429

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.279

Low

759134

SEG1
Eisosome protein SEG1

1

0

High-throughput

0.279

Low

759127

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.269

Low

697791

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

754945

HTD2
Hydroxyacyl-thioester dehydratase type 2, mitochondrial

1

0

High-throughput

0.261

Low

759113

GTT3
Glutathione transferase 3

1

0

High-throughput

0.261

Low

759136

YMI3
Putative uncharacterized protein YML083C

1

0

High-throughput

0.261

Low

759140

YL001
FAS1 domain-containing protein YLR001C

1

0

High-throughput

0.261

Low

410797

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

537418

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

759125

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024