Protein: CYK2
Cytokinesis protein 2 (Homolog of CDC15 protein 1)

Gene: CYK2, HOF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: Q05080

Gene Ontology (top 5):
GO:0000142 - cellular bud neck contractile ring
GO:0000144 - cellular bud neck septin ring
GO:0000281 - mitotic cytokinesis
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748821

RGD1
RHO GTPase-activating protein RGD1

2

7

High-throughput

0.801

High

983047

CYK2
Cytokinesis protein 2

2

17

Small-scale

0.783

High

865964

INN1
Ingression protein 1

14

2

Small-scale

0.762

High

983048

CYK3
Cytokinesis protein 3

6

1

Small-scale

0.741

High

773875

BNR1
BNI1-related protein 1

4

11

Small-scale

0.708

High

629585

CDC10
Cell division control protein 10

4

1

Small-scale

0.690

High

741559

VRP1
Verprolin

3

5

Small-scale

0.677

High

983058

LAS17
Proline-rich protein LAS17

3

20

Small-scale

0.660

High

765593

SAP1
Protein SAP1

2

3

High-throughput

0.643

High

765456

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

2

4

High-throughput

0.632

High

811146

BBC1
Myosin tail region-interacting protein MTI1

2

11

High-throughput

0.620

High

767918

SHO1
High osmolarity signaling protein SHO1

2

0

Small-scale

0.616

High

983056

IQG1
Ras GTPase-activating-like protein IQG1

2

4

Small-scale

0.614

High

743189

BOB1
Protein BOB1

2

4

Small-scale

0.613

High

767018

FIR1
Factor interacting with REF2

2

2

Small-scale

0.613

High

624316

GRR1
SCF E3 ubiquitin ligase complex F-box protein GRR1

2

3

Small-scale

0.611

High

704936

PACC
pH-response transcription factor pacC/RIM101

2

0

High-throughput

0.605

High

983051

NBA1
Protein NBA1

2

0

Small-scale

0.605

High

446234

MYO1
Myosin-1

2

5

Small-scale

0.595

High

983061

AIM44
Altered inheritance of mitochondria protein 44

2

0

Small-scale

0.588

High

690560

CDC12
Cell division control protein 12

2

1

Small-scale

0.584

High

613081

SPA2
Protein SPA2

1

5

Small-scale

0.573

High

492423

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.571

High

535993

CHS2
Chitin synthase 2

2

0

Small-scale

0.569

High

773906

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.568

High

859861

YBP2
YAP1-binding protein 2

1

0

High-throughput

0.543

High

710623

SKT5
Chitin synthase regulator SKT5

1

2

Small-scale

0.543

High

690270

CDC3
Cell division control protein 3

1

1

Small-scale

0.541

High

691243

MKK2
MAP kinase kinase MKK2/SSP33

1

6

High-throughput

0.541

High

699567

BEM3
GTPase-activating protein BEM3

1

7

High-throughput

0.541

High

711000

HSL1
Probable serine/threonine-protein kinase HSL1

1

1

High-throughput

0.541

High

810676

ALY2
Arrestin-related trafficking adapter 3

1

3

High-throughput

0.541

High

820025

BRO1
Vacuolar-sorting protein BRO1

1

2

High-throughput

0.541

High

859020

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.541

High

859632

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.541

High

866383

NIS1
Protein NIS1

1

1

High-throughput

0.541

High

979568

MYO5
Myosin-5

1

6

High-throughput

0.541

High

983053

ULS1
ATP-dependent helicase ULS1

1

3

High-throughput

0.541

High

983059

ATC8
Probable phospholipid-transporting ATPase DNF3

1

2

High-throughput

0.541

High

774499

MOB1
DBF2 kinase activator protein MOB1

1

0

Small-scale

0.529

High

690342

CDC11
Cell division control protein 11

1

2

Small-scale

0.527

High

693159

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

3

Small-scale

0.527

High

634972

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

3

High-throughput

0.518

High

866343

APP1
Phosphatidate phosphatase APP1

1

2

High-throughput

0.518

High

562285

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.518

High

812301

BUD4
Bud site selection protein 4

1

0

High-throughput

0.518

High

983054

DSE3
Protein DSE3

1

0

High-throughput

0.518

High

859578

MLC1
Myosin light chain 1

1

1

Small-scale

0.516

High

784659

BNI1
Protein BNI1

1

11

Small-scale

0.508

High

434780

PBS2
MAP kinase kinase PBS2

1

6

High-throughput

0.501

High

605586

DBF2
Cell cycle protein kinase DBF2

1

2

Small-scale

0.501

High

744097

AGP2
General amino acid permease AGP2

1

1

High-throughput

0.501

High

887677

ACT
Actin

1

4

Small-scale

0.501

High

747566

AIM3
Altered inheritance of mitochondria protein 3

1

5

High-throughput

0.494

High

983050

YO036
Uncharacterized protein YOL036W

1

1

High-throughput

0.494

High

754351

GIC1
GTPase-interacting component 1

1

0

High-throughput

0.486

High

539411

KSS1
Mitogen-activated protein kinase KSS1

1

2

High-throughput

0.481

High

624721

CG22
G2/mitotic-specific cyclin-2

1

1

Small-scale

0.481

High

730594

MYO3
Myosin-3

1

6

Small-scale

0.481

High

983049

SHS1
Seventh homolog of septin 1

1

5

Small-scale

0.481

High

339836

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

752272

KIC1
Serine/threonine-protein kinase KIC1

1

0

High-throughput

0.480

High

767038

ZRG8
Zinc-regulated protein 8

1

0

High-throughput

0.480

High

758902

ATU2
Copper-transporting ATPase

1

1

High-throughput

0.479

High

860473

VHT1
Vitamin H transporter

1

1

High-throughput

0.479

High

978689

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

983052

ENB1
Siderophore iron transporter ENB1

1

2

High-throughput

0.479

High

546217

SYKC
Lysine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

664539

HRR25
Casein kinase I homolog HRR25

1

0

Small-scale

0.458

High

704182

DOM34
Protein DOM34

1

0

High-throughput

0.458

High

778769

FET4
Low-affinity Fe(2+) transport protein

1

0

High-throughput

0.458

High

811713

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

864765

FRE4
Ferric reductase transmembrane component 4

1

0

High-throughput

0.458

High

759324

MET30
F-box protein MET30

1

2

High-throughput

0.457

High

983055

SOG2
Leucine-rich repeat-containing protein SOG2

1

1

High-throughput

0.457

High

494947

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

512711

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

633567

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

695510

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

696066

HSP79
Heat shock protein homolog SSE2

1

12

High-throughput

0.445

High

754703

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

766208

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

979535

HSP31
Glutathione-independent glyoxalase HSP31

1

1

High-throughput

0.445

High

482790

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.439

High

629933

ATX10
Ataxin-10 homolog

1

0

High-throughput

0.438

High

743675

HMT1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

765934

SIT1
Siderophore iron transporter 1

1

3

High-throughput

0.437

High

612274

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

773754

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

811461

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

983057

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

595071

NUP1
Nucleoporin NUP1

1

1

High-throughput

0.417

High

796958

YFG3
Putative UPF0320 protein YFL063W

1

1

High-throughput

0.417

High

812683

YJ9Z
Putative UPF0320 protein YJR162C

1

1

High-throughput

0.417

High

628468

SIS1
Protein SIS1

1

4

High-throughput

0.407

High

741365

DHSD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

1

0

High-throughput

0.282

High

966347

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

High-throughput

0.282

High

977795

SPO71
Prospore membrane adapter protein SPO71

1

0

High-throughput

0.282

High

691856

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.265

Low

983060

SRN2
Protein SRN2

1

0

High-throughput

0.265

Low

762869

YAN8
Uncharacterized protein YAR068W

1

0

High-throughput

0.261

Low

581120

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.249

Low

819990

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

High-throughput

0.249

Low

841435

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

979157

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

141959

YA069
Putative uncharacterized protein YAL069W

1

0

High-throughput

0.238

Low

748388

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

760954

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024