Protein: LEU3
3-isopropylmalate dehydrogenase (3-IPM-DH) (IMDH) (EC 1.1.1.85) (Beta-IPM dehydrogenase)

Gene: LEU3, leu1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 11
UniProt ID: P18869

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003862 - 3-isopropylmalate dehydrogenase activity
GO:0005829 - cytosol
GO:0009098 - L-leucine biosynthetic process
GO:0051287 - NAD binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

617629

LEU3
3-isopropylmalate dehydrogenase

1

17

High-throughput

0.621

High

153950

NC2B
Negative cofactor 2 complex subunit beta

1

1

High-throughput

0.481

High

149010

PHD1
Histone deacetylase phd1

1

1

High-throughput

0.479

High

150572

ANM3
Ribosomal protein arginine N-methyltransferase rmt3

1

3

High-throughput

0.479

High

153095

SEM1
26S proteasome complex subunit rpn15

1

2

High-throughput

0.479

High

617632

DJ1
Glutathione-independent glyoxalase DJ-1

1

0

High-throughput

0.458

High

206391

FFT3
ATP-dependent helicase fft3

1

3

High-throughput

0.437

High

617631

TEA1
Tip elongation aberrant protein 1

1

1

High-throughput

0.437

High

617630

DIS3
Exosome complex exonuclease dis3

1

0

High-throughput

0.249

Low

153523

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025