Protein: DYHC
Dynein heavy chain, cytoplasmic (Dynein heavy chain, cytosolic) (DYHC)

Gene: DYHC, DYN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P36022

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000132 - establishment of mitotic spindle orientation
GO:0000235 - astral microtubule
GO:0000741 - karyogamy
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

731315

LIS1
Nuclear distribution protein PAC1

7

9

Small-scale

0.961

High

731295

DYHC
Dynein heavy chain, cytoplasmic

4

5

Small-scale

0.884

High

360839

TBB
Tubulin beta chain

3

2

Small-scale

0.845

High

454279

TBA1
Tubulin alpha-1 chain

3

2

Small-scale

0.845

High

731358

DYN3
Cytoplasmic dynein intermediate light chain DYN3

4

0

Small-scale

0.837

High

731348

DYL1
Dynein light chain 1, cytoplasmic

5

6

Small-scale

0.704

High

731345

NUM1
Nuclear migration protein NUM1

2

9

Small-scale

0.611

High

731307

KEL1
Kelch repeat-containing protein 1

2

1

High-throughput

0.595

High

731324

PAC11
WD repeat-containing protein PAC11

2

0

Small-scale

0.592

High

731369

RIO1
Serine/threonine-protein kinase RIO1

2

1

Small-scale

0.586

High

731325

BNI1
Protein BNI1

2

1

Small-scale

0.584

High

585299

MYO2
Myosin-2

2

0

Small-scale

0.559

High

561866

TUP1
General transcriptional corepressor TUP1

1

7

High-throughput

0.555

High

345238

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

2

1

High-throughput

0.543

High

356403

H4
Histone H4

2

3

High-throughput

0.537

High

731366

KEL3
Kelch repeat-containing protein 3

1

1

High-throughput

0.515

High

700760

SMC1
Structural maintenance of chromosomes protein 1

1

2

High-throughput

0.508

High

731300

SHE1
Mitotic spindle-associated protein SHE1

1

0

Small-scale

0.504

High

731304

UMP1
Proteasome maturation factor UMP1

1

0

High-throughput

0.493

High

731335

SP105
Spindle pole body component SPC105

1

0

High-throughput

0.493

High

731340

DCP2
m7GpppN-mRNA hydrolase

1

0

High-throughput

0.486

High

436832

SWI5
Transcriptional factor SWI5

1

1

High-throughput

0.481

High

514551

BIK1
Nuclear fusion protein BIK1

1

5

High-throughput

0.481

High

623459

KPC1
Protein kinase C-like 1

1

1

High-throughput

0.481

High

688872

SMY1
Kinesin-related protein SMY1

1

4

High-throughput

0.481

High

731298

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

4

High-throughput

0.481

High

731305

ETP1
RING finger protein ETP1

1

1

High-throughput

0.481

High

731309

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.481

High

731311

RGA1
Rho-type GTPase-activating protein 1

1

1

High-throughput

0.481

High

731314

SNF7
Vacuolar-sorting protein SNF7

1

1

High-throughput

0.481

High

731320

TBP6
Probable 26S proteasome subunit YTA6

1

4

High-throughput

0.481

High

731332

HMS2
Probable transcription factor HMS2

1

1

High-throughput

0.481

High

731338

YG3A
Uncharacterized protein YGR130C

1

7

High-throughput

0.481

High

731341

CNM67
Chaotic nuclear migration protein 67

1

5

High-throughput

0.481

High

731342

CBK1
Serine/threonine-protein kinase CBK1

1

4

High-throughput

0.481

High

731354

VPS20
Vacuolar protein sorting-associated protein 20

1

1

High-throughput

0.481

High

731364

IRC3
Putative ATP-dependent helicase IRC3

1

1

High-throughput

0.481

High

660068

KIP2
Kinesin-like protein KIP2

1

0

Small-scale

0.480

High

731346

CDC14
Tyrosine-protein phosphatase CDC14

1

4

Small-scale

0.479

High

145907

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.460

High

446146

MYO1
Myosin-1

1

0

High-throughput

0.460

High

629710

STE50
Protein STE50

1

0

High-throughput

0.460

High

703584

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

731296

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

731301

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

731316

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

731319

VFA1
VPS4-associated protein 1

1

0

High-throughput

0.460

High

731328

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.460

High

731334

PSP1
Protein PSP1

1

0

High-throughput

0.460

High

731336

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.460

High

731343

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.460

High

731344

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

731347

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.460

High

731362

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

731310

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.458

High

731368

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

345262

STF1
F(1)-ATPase inhibitor STF1, mitochondrial

1

1

High-throughput

0.439

High

655697

PRP45
Pre-mRNA-processing protein 45

1

2

Small-scale

0.439

High

728678

BDF1
Bromodomain-containing factor 1

1

2

High-throughput

0.439

High

731308

SKN7
Transcription factor SKN7

1

1

High-throughput

0.439

High

731313

HPH2
Protein HPH2

1

1

High-throughput

0.439

High

731318

TSC11
Target of rapamycin complex 2 subunit TSC11

1

1

High-throughput

0.439

High

731321

BNR1
BNI1-related protein 1

1

1

High-throughput

0.439

High

731322

NDC80
Kinetochore protein NDC80

1

9

High-throughput

0.439

High

731323

MAD1
Spindle assembly checkpoint component MAD1

1

5

High-throughput

0.439

High

731339

AP18B
Clathrin coat assembly protein AP180B

1

1

High-throughput

0.439

High

731373

RLF2
Chromatin assembly factor 1 subunit p90

1

3

High-throughput

0.439

High

731375

HPH1
Protein HPH1

1

1

High-throughput

0.439

High

731350

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.417

High

626429

ERG6
Sterol 24-C-methyltransferase ERG6

2

0

Small-scale

0.326

High

731355

SPC24
Kinetochore protein SPC24

2

0

High-throughput

0.319

High

731317

SPC25
Kinetochore protein SPC25

2

0

High-throughput

0.310

High

561946

SEN2
tRNA-splicing endonuclease subunit SEN2

1

0

High-throughput

0.251

Low

599908

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

634945

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

679784

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.251

Low

702651

TYE7
Transcription factor TYE7

1

0

High-throughput

0.251

Low

731297

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low

731302

RXT2
Transcriptional regulatory protein RXT2

1

0

High-throughput

0.251

Low

731303

EXO84
Exocyst complex component EXO84

1

0

High-throughput

0.251

Low

731306

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

731312

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.251

Low

731326

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.251

Low

731327

BLM10
Proteasome activator BLM10

1

0

High-throughput

0.251

Low

731329

STB2
Protein STB2

1

0

High-throughput

0.251

Low

731330

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.251

Low

731331

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

731333

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

731337

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

731349

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

731351

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

731353

SHE9
Sensitive to high expression protein 9, mitochondrial

1

0

High-throughput

0.251

Low

731356

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

731357

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

731359

HOB2
Protein YPR117W

1

0

High-throughput

0.251

Low

731360

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.251

Low

731361

SEC10
Exocyst complex component SEC10

1

0

High-throughput

0.251

Low

731363

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

731365

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.251

Low

731367

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.251

Low

731370

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

731371

NCA2
Nuclear control of ATPase protein 2

1

0

High-throughput

0.251

Low

731372

ERP3
Protein ERP3

1

0

High-throughput

0.251

Low

731374

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.251

Low

619447

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

661893

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

731299

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

731352

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024