Protein: SIN3B
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)

Gene: SIN3B
Organism: Homo sapiens
Interactions: 132
UniProt ID: O75182

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000805 - X chromosome
GO:0000806 - Y chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

257821

PHF12
PHD finger protein 12

4

17

High-throughput

0.895

High

257729

SAP30
Histone deacetylase complex subunit SAP30

4

4

Small-scale

0.892

High

257779

HDAC1
Histone deacetylase 1

12

18

Small-scale

0.758

High

257843

MO4L1
Mortality factor 4-like protein 1

7

5

Small-scale

0.746

High

257788

RBBP7
Histone-binding protein RBBP7

6

9

High-throughput

0.736

High

257834

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

5

9

Small-scale

0.723

High

257811

GATD1
GATA zinc finger domain-containing protein 1

5

1

High-throughput

0.714

High

257815

HDAC2
Histone deacetylase 2

5

19

Small-scale

0.703

High

257744

KDM5A
Lysine-specific demethylase 5A

4

2

Small-scale

0.699

High

257800

EMSY
BRCA2-interacting transcriptional repressor EMSY

4

4

High-throughput

0.694

High

257771

RBBP4
Histone-binding protein RBBP4

3

10

High-throughput

0.675

High

257829

SP130
Histone deacetylase complex subunit SAP130

3

6

High-throughput

0.667

High

257837

SHCAF
SIN3-HDAC complex-associated factor

3

1

Small-scale

0.667

High

257785

MO4L2
Mortality factor 4-like protein 2

3

5

Small-scale

0.640

High

257735

ESR1
Estrogen receptor

3

6

Small-scale

0.633

High

179003

TNC18
Trinucleotide repeat-containing gene 18 protein

2

4

High-throughput

0.628

High

257823

SIN3A
Paired amphipathic helix protein Sin3a

2

3

High-throughput

0.628

High

257825

PHF23
PHD finger protein 23

2

2

High-throughput

0.628

High

257831

ING2
Inhibitor of growth protein 2

2

10

High-throughput

0.628

High

257810

SAP25
Histone deacetylase complex subunit SAP25

1

2

Small-scale

0.618

High

257775

REST
RE1-silencing transcription factor

2

1

Small-scale

0.611

High

257734

MYC
Myc proto-oncogene protein

2

19

Small-scale

0.611

High

257743

ARI4A
AT-rich interactive domain-containing protein 4A

2

9

Small-scale

0.611

High

257792

ARI4B
AT-rich interactive domain-containing protein 4B

2

8

High-throughput

0.611

High

257740

ANDR
Androgen receptor

2

6

Small-scale

0.584

High

257778

IKZF1
DNA-binding protein Ikaros

2

7

Small-scale

0.584

High

257795

RN220
E3 ubiquitin-protein ligase RNF220

1

1

Small-scale

0.578

High

257769

ZBT16
Zinc finger and BTB domain-containing protein 16

1

1

Small-scale

0.573

High

257840

MRGBP
MRG/MORF4L-binding protein

2

0

Small-scale

0.559

High

257736

P53
Cellular tumor antigen p53

1

2

Small-scale

0.552

High

257748

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

2

0

Small-scale

0.551

High

257753

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.536

High

257765

FOXK2
Forkhead box protein K2

1

6

High-throughput

0.536

High

257768

AKA12
A-kinase anchor protein 12

1

2

High-throughput

0.536

High

257781

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

257796

TASO2
Protein TASOR 2

1

1

High-throughput

0.536

High

257805

TF2LX
Homeobox protein TGIF2LX

1

4

High-throughput

0.536

High

257813

BBX
HMG box transcription factor BBX

1

7

High-throughput

0.536

High

257844

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

257846

ING1
Inhibitor of growth protein 1

1

11

High-throughput

0.536

High

257852

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.536

High

257758

HCFC1
Host cell factor 1

1

3

Small-scale

0.515

High

211439

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.513

High

257776

STX3
Syntaxin-3

1

0

High-throughput

0.513

High

257791

RN151
RING finger protein 151

1

0

High-throughput

0.513

High

257839

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.513

High

160282

AURKA
Aurora kinase A

1

3

Small-scale

0.501

High

257756

SMCA2
Probable global transcription activator SNF2L2

1

16

Small-scale

0.501

High

257757

SMCA4
Transcription activator BRG1

1

17

Small-scale

0.501

High

257761

CSN2
COP9 signalosome complex subunit 2

1

1

Small-scale

0.501

High

257772

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

2

Small-scale

0.501

High

257783

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

5

Small-scale

0.501

High

257816

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

1

Small-scale

0.501

High

257850

HDAC9
Histone deacetylase 9

1

20

Small-scale

0.501

High

257747

SCN4A
Sodium channel protein type 4 subunit alpha

1

1

High-throughput

0.489

High

257806

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.489

High

146779

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.479

High

231905

KDM1A
Lysine-specific histone demethylase 1A

1

3

High-throughput

0.479

High

232743

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

253956

MTG16
Protein CBFA2T3

1

2

Small-scale

0.479

High

257730

E2F6
Transcription factor E2F6

1

3

Small-scale

0.479

High

257731

MTA2
Metastasis-associated protein MTA2

1

7

High-throughput

0.479

High

257732

MBD3
Methyl-CpG-binding domain protein 3

1

4

High-throughput

0.479

High

257733

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

Small-scale

0.479

High

257739

MYBB
Myb-related protein B

1

5

High-throughput

0.479

High

257741

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

257742

SMCA1
Probable global transcription activator SNF2L1

1

17

High-throughput

0.479

High

257749

PBX1
Pre-B-cell leukemia transcription factor 1

1

6

Small-scale

0.479

High

257751

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

257754

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

257755

MXI1
Max-interacting protein 1

1

17

Small-scale

0.479

High

257759

ZN131
Zinc finger protein 131

1

2

High-throughput

0.479

High

257760

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

2

High-throughput

0.479

High

257762

H4
Histone H4

1

2

High-throughput

0.479

High

257763

H31
Histone H3.1

1

5

High-throughput

0.479

High

257764

RED1
Double-stranded RNA-specific editase 1

1

2

High-throughput

0.479

High

257766

MYT1
Myelin transcription factor 1

1

2

Small-scale

0.479

High

257767

TFAP4
Transcription factor AP-4

1

2

Small-scale

0.479

High

257773

BPTF
Nucleosome-remodeling factor subunit BPTF

1

8

High-throughput

0.479

High

257774

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

12

High-throughput

0.479

High

257777

MTA1
Metastasis-associated protein MTA1

1

7

High-throughput

0.479

High

257780

KLF9
Krueppel-like factor 9

1

10

High-throughput

0.479

High

257782

MDC1
Mediator of DNA damage checkpoint protein 1

1

3

High-throughput

0.479

High

257784

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

18

High-throughput

0.479

High

257786

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

Small-scale

0.479

High

257787

ELF2
ETS-related transcription factor Elf-2

1

4

High-throughput

0.479

High

257789

SMN
Survival motor neuron protein

1

1

Small-scale

0.479

High

257793

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

9

High-throughput

0.479

High

257794

LIN9
Protein lin-9 homolog

1

3

High-throughput

0.479

High

257797

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

257799

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

257801

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.479

High

257802

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

257804

P66A
Transcriptional repressor p66-alpha

1

5

High-throughput

0.479

High

257807

BAP18
Chromatin complexes subunit BAP18

1

1

High-throughput

0.479

High

257808

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

257809

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

11

High-throughput

0.479

High

257812

P66B
Transcriptional repressor p66-beta

1

5

High-throughput

0.479

High

257814

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

257817

PF21A
PHD finger protein 21A

1

17

High-throughput

0.479

High

257818

LIN37
Protein lin-37 homolog

1

1

High-throughput

0.479

High

257819

Z512B
Zinc finger protein 512B

1

3

High-throughput

0.479

High

257820

PWP2A
PWWP domain-containing protein 2A

1

4

High-throughput

0.479

High

257822

CIC
Protein capicua homolog

1

9

High-throughput

0.479

High

257824

MTA3
Metastasis-associated protein MTA3

1

10

High-throughput

0.479

High

257826

KLF16
Krueppel-like factor 16

1

10

Small-scale

0.479

High

257828

WWTR1
WW domain-containing transcription regulator protein 1

1

3

High-throughput

0.479

High

257830

BRD8
Bromodomain-containing protein 8

1

7

High-throughput

0.479

High

257832

BC11A
B-cell lymphoma/leukemia 11A

1

1

High-throughput

0.479

High

257833

IKZF4
Zinc finger protein Eos

1

7

Small-scale

0.479

High

257836

BRMS1
Breast cancer metastasis-suppressor 1

1

9

Small-scale

0.479

High

257841

ZBTB4
Zinc finger and BTB domain-containing protein 4

1

1

Small-scale

0.479

High

257842

MBD2
Methyl-CpG-binding domain protein 2

1

4

High-throughput

0.479

High

257847

RCOR1
REST corepressor 1

1

10

High-throughput

0.479

High

257848

IKZF2
Zinc finger protein Helios

1

7

Small-scale

0.479

High

257849

IKZF3
Zinc finger protein Aiolos

1

7

Small-scale

0.479

High

257851

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

9

Small-scale

0.479

High

257738

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

257745

C2TA
MHC class II transactivator

1

0

Small-scale

0.458

High

257746

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.458

High

257750

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

257803

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.458

High

257827

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.458

High

257853

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.458

High

257770

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.437

High

257845

HMGX4
HMG domain-containing protein 4

1

8

High-throughput

0.437

High

257752

RFX5
DNA-binding protein RFX5

1

0

Small-scale

0.426

High

257835

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

257790

H31T
Histone H3.1t

1

5

High-throughput

0.408

High

257838

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.279

Low

257737

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

257798

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024