Protein: SDS3
Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog)

Gene: SDS3, SUDS3
Organism: Homo sapiens
Interactions: 116
UniProt ID: Q9H7L9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006338 - chromatin remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038717

HDAC1
Histone deacetylase 1

9

9

Small-scale

0.756

High

1302448

SIN3A
Paired amphipathic helix protein Sin3a

7

9

Small-scale

0.749

High

257834

SIN3B
Paired amphipathic helix protein Sin3b

5

9

Small-scale

0.723

High

1270447

HDAC2
Histone deacetylase 2

5

9

Small-scale

0.712

High

997905

RBBP4
Histone-binding protein RBBP4

3

5

High-throughput

0.675

High

265261

SAP30
Histone deacetylase complex subunit SAP30

3

3

High-throughput

0.667

High

983445

MAD1
Max dimerization protein 1

3

9

High-throughput

0.667

High

1083392

RBBP7
Histone-binding protein RBBP7

3

5

High-throughput

0.667

High

1217197

LACC1
Purine nucleoside phosphorylase LACC1

3

1

High-throughput

0.667

High

1328463

ING2
Inhibitor of growth protein 2

3

11

Small-scale

0.667

High

1333157

SHCAF
SIN3-HDAC complex-associated factor

3

2

Small-scale

0.667

High

934482

CSK21
Casein kinase II subunit alpha

2

3

High-throughput

0.643

High

1333156

BRMS1
Breast cancer metastasis-suppressor 1

2

6

Small-scale

0.633

High

1169251

ZN704
Zinc finger protein 704

2

2

High-throughput

0.628

High

1312991

PHF23
PHD finger protein 23

2

1

High-throughput

0.628

High

1117703

ARI4B
AT-rich interactive domain-containing protein 4B

2

4

Small-scale

0.584

High

1260543

GATD1
GATA zinc finger domain-containing protein 1

2

2

High-throughput

0.584

High

1327624

SP130
Histone deacetylase complex subunit SAP130

2

5

Small-scale

0.584

High

320733

LDOC1
Protein LDOC1

2

0

High-throughput

0.580

High

1314322

MAD3
Max dimerization protein 3

2

9

High-throughput

0.574

High

1302047

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.569

High

228713

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1163946

U17L2
Ubiquitin carboxyl-terminal hydrolase 17

1

0

Small-scale

0.537

High

470161

H2AZ
Histone H2A.Z

1

2

High-throughput

0.536

High

586987

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

666508

ARI4A
AT-rich interactive domain-containing protein 4A

1

4

High-throughput

0.536

High

898195

MAX
Protein max

1

7

High-throughput

0.536

High

952878

FOXK1
Forkhead box protein K1

1

7

High-throughput

0.536

High

964260

FOXK2
Forkhead box protein K2

1

7

High-throughput

0.536

High

1050788

FHL2
Four and a half LIM domains protein 2

1

2

High-throughput

0.536

High

1216211

TF2LX
Homeobox protein TGIF2LX

1

7

High-throughput

0.536

High

1326061

TGIF2
Homeobox protein TGIF2

1

7

High-throughput

0.536

High

1333162

LHX3
LIM/homeobox protein Lhx3

1

1

High-throughput

0.536

High

1333164

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

1333167

ING1
Inhibitor of growth protein 1

1

13

High-throughput

0.536

High

1333155

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

6

Small-scale

0.527

High

595417

LMNB1
Lamin-B1

1

0

High-throughput

0.513

High

848293

HCFC1
Host cell factor 1

1

0

Small-scale

0.513

High

958770

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

1302732

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

1

0

High-throughput

0.513

High

876275

MANF
Mesencephalic astrocyte-derived neurotrophic factor

1

0

High-throughput

0.493

High

1291295

DYL2
Dynein light chain 2, cytoplasmic

1

0

High-throughput

0.493

High

1333163

DKK2
Dickkopf-related protein 2

1

2

High-throughput

0.489

High

890845

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

1130597

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.480

High

146867

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.479

High

158857

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.479

High

182911

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

198056

PHF1
PHD finger protein 1

1

3

High-throughput

0.479

High

211967

TLX3
T-cell leukemia homeobox protein 3

1

3

High-throughput

0.479

High

229496

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

9

High-throughput

0.479

High

233893

HBP1
HMG box-containing protein 1

1

10

High-throughput

0.479

High

244946

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

268287

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

296140

MTA2
Metastasis-associated protein MTA2

1

6

High-throughput

0.479

High

316996

KLF8
Krueppel-like factor 8

1

12

High-throughput

0.479

High

328657

MBD3
Methyl-CpG-binding domain protein 3

1

3

High-throughput

0.479

High

486969

MYBB
Myb-related protein B

1

1

High-throughput

0.479

High

487767

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

620205

PAX7
Paired box protein Pax-7

1

5

High-throughput

0.479

High

658736

SMCA1
Probable global transcription activator SNF2L1

1

9

High-throughput

0.479

High

727591

HNF1B
Hepatocyte nuclear factor 1-beta

1

6

High-throughput

0.479

High

917930

H4
Histone H4

1

2

High-throughput

0.479

High

981925

RON
Macrophage-stimulating protein receptor

1

1

High-throughput

0.479

High

999097

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

1017352

BPTF
Nucleosome-remodeling factor subunit BPTF

1

10

High-throughput

0.479

High

1018698

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

9

High-throughput

0.479

High

1024522

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

1024880

KLF10
Krueppel-like factor 10

1

9

High-throughput

0.479

High

1031950

MTA1
Metastasis-associated protein MTA1

1

6

High-throughput

0.479

High

1043590

CUL4B
Cullin-4B

1

1

Small-scale

0.479

High

1046665

KLF9
Krueppel-like factor 9

1

12

High-throughput

0.479

High

1059878

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

9

High-throughput

0.479

High

1061785

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

11

High-throughput

0.479

High

1063624

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1077601

ELF2
ETS-related transcription factor Elf-2

1

6

High-throughput

0.479

High

1080351

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.479

High

1129658

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

6

High-throughput

0.479

High

1137050

LIN9
Protein lin-9 homolog

1

1

High-throughput

0.479

High

1205816

P66A
Transcriptional repressor p66-alpha

1

3

High-throughput

0.479

High

1221074

BAP18
Chromatin complexes subunit BAP18

1

1

High-throughput

0.479

High

1254925

SP7
Transcription factor Sp7

1

13

High-throughput

0.479

High

1255046

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

9

High-throughput

0.479

High

1260516

ZN296
Zinc finger protein 296

1

4

High-throughput

0.479

High

1263975

P66B
Transcriptional repressor p66-beta

1

3

High-throughput

0.479

High

1292970

LIN37
Protein lin-37 homolog

1

1

High-throughput

0.479

High

1296249

Z512B
Zinc finger protein 512B

1

1

High-throughput

0.479

High

1298458

PWP2A
PWWP domain-containing protein 2A

1

2

High-throughput

0.479

High

1300613

PHF12
PHD finger protein 12

1

10

High-throughput

0.479

High

1300944

CIC
Protein capicua homolog

1

7

High-throughput

0.479

High

1304699

FEV
Protein FEV

1

7

High-throughput

0.479

High

1312023

MTA3
Metastasis-associated protein MTA3

1

6

High-throughput

0.479

High

1315357

KLF16
Krueppel-like factor 16

1

11

High-throughput

0.479

High

1319436

BC11B
B-cell lymphoma/leukemia 11B

1

4

High-throughput

0.479

High

1328474

BC11A
B-cell lymphoma/leukemia 11A

1

4

High-throughput

0.479

High

1332321

SOX17
Transcription factor SOX-17

1

8

High-throughput

0.479

High

1333161

MBD2
Methyl-CpG-binding domain protein 2

1

3

High-throughput

0.479

High

1333168

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

1333169

MTF2
Metal-response element-binding transcription factor 2

1

3

High-throughput

0.479

High

649160

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

0

Small-scale

0.458

High

931869

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1056990

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

1071702

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

1082395

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.458

High

1161838

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1188870

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1333158

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1333160

ZN219
Zinc finger protein 219

1

0

High-throughput

0.458

High

1333165

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

297677

RHBT1
Rho-related BTB domain-containing protein 1

1

3

High-throughput

0.437

High

1317623

RHBT2
Rho-related BTB domain-containing protein 2

1

3

High-throughput

0.437

High

1333166

HMGX4
HMG domain-containing protein 4

1

8

High-throughput

0.437

High

995226

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1252875

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1333159

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024