Protein: SH22A
SH2 domain-containing protein 2A (SH2 domain-containing adapter protein) (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein)

Gene: SH22A, SH2D2A
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9NP31

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

411870

LCK
Tyrosine-protein kinase Lck

3

19

Small-scale

0.848

High

655475

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

High-throughput

0.819

High

983674

FAK1
Focal adhesion kinase 1

2

20

High-throughput

0.819

High

1267442

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.819

High

1342256

ASB3
Ankyrin repeat and SOCS box protein 3

2

10

High-throughput

0.819

High

339014

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.778

High

383991

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

147448

SOCS3
Suppressor of cytokine signaling 3

2

19

High-throughput

0.767

High

776824

STAT3
Signal transducer and activator of transcription 3

2

16

High-throughput

0.767

High

802738

CRK
Adapter molecule crk

2

19

High-throughput

0.767

High

796654

KSYK
Tyrosine-protein kinase SYK

1

20

High-throughput

0.740

High

441569

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499289

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

1342255

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

12

High-throughput

0.692

High

523160

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.681

High

729692

VGFR2
Vascular endothelial growth factor receptor 2

1

20

Small-scale

0.681

High

1332898

PEAK1
Inactive tyrosine-protein kinase PEAK1

3

20

High-throughput

0.667

High

602006

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

1071018

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

1283000

TET5B
Terminal nucleotidyltransferase 5B

2

2

High-throughput

0.634

High

1294574

TET5A
Terminal nucleotidyltransferase 5A

2

2

High-throughput

0.634

High

1060065

LASP1
LIM and SH3 domain protein 1

2

20

High-throughput

0.628

High

1239582

KDM1B
Lysine-specific histone demethylase 2

3

3

High-throughput

0.609

High

1342252

PKHB1
Pleckstrin homology domain-containing family B member 1

2

0

High-throughput

0.607

High

506844

SPTB1
Spectrin beta chain, erythrocytic

2

20

High-throughput

0.594

High

1103963

LRRF1
Leucine-rich repeat flightless-interacting protein 1

2

1

High-throughput

0.594

High

1252494

LNX1
E3 ubiquitin-protein ligase LNX

2

20

High-throughput

0.594

High

1267550

TSC1
Hamartin

2

20

High-throughput

0.594

High

1331085

ZHX3
Zinc fingers and homeoboxes protein 3

2

3

High-throughput

0.594

High

1342253

DP13A
DCC-interacting protein 13-alpha

2

19

High-throughput

0.594

High

875339

TERA
Transitional endoplasmic reticulum ATPase

1

3

Small-scale

0.586

High

1154524

NAA16
N-alpha-acetyltransferase 16, NatA auxiliary subunit

2

6

High-throughput

0.576

High

1078673

SMAD2
Mothers against decapentaplegic homolog 2

1

6

Small-scale

0.573

High

950296

SMAD3
Mothers against decapentaplegic homolog 3

1

6

Small-scale

0.561

High

1342254

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

14

Small-scale

0.552

High

1239652

ZSCA1
Zinc finger and SCAN domain-containing protein 1

2

9

High-throughput

0.542

High

1026882

MK07
Mitogen-activated protein kinase 7

1

9

High-throughput

0.541

High

487778

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

862106

DAPK1
Death-associated protein kinase 1

1

17

High-throughput

0.536

High

1035411

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.536

High

978245

ARI5A
AT-rich interactive domain-containing protein 5A

2

1

High-throughput

0.526

High

1342257

RA54B
DNA repair and recombination protein RAD54B

1

9

High-throughput

0.504

High

1105491

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

5

High-throughput

0.501

High

1140791

RN123
E3 ubiquitin-protein ligase RNF123

1

7

High-throughput

0.479

High

1044172

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

16

High-throughput

0.445

High

1255264

HAVR2
Hepatitis A virus cellular receptor 2

1

6

Small-scale

0.442

High

1138439

DC121
DDB1- and CUL4-associated factor 12-like protein 1

2

0

High-throughput

0.331

High

1168324

PPR21
Protein phosphatase 1 regulatory subunit 21

2

0

High-throughput

0.310

High

1204127

CQ082
Putative uncharacterized protein LINC02875

2

0

High-throughput

0.300

High

850304

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

304484

FSBP
Fibrinogen silencer-binding protein

1

0

High-throughput

0.272

Low


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Last updated: 15 Jul 2024