Protein: JIP1
C-Jun-amino-terminal kinase-interacting protein 1 (JIP-1) (JNK-interacting protein 1) (Islet-brain 1) (IB-1) (JNK MAP kinase scaffold protein 1) (Mitogen-activated protein kinase 8-interacting protein 1)

Gene: JIP1, MAPK8IP1
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9UQF2

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

396065

A4
Amyloid-beta precursor protein

7

12

Small-scale

0.969

High

1032958

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

3

11

Small-scale

0.879

High

682078

AKT1
RAC-alpha serine/threonine-protein kinase

3

9

Small-scale

0.866

High

201469

M3K7
Mitogen-activated protein kinase kinase kinase 7

3

13

Small-scale

0.847

High

1083525

M3K11
Mitogen-activated protein kinase kinase kinase 11

2

9

Small-scale

0.834

High

384031

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

20

High-throughput

0.828

High

965176

ANK2
Ankyrin-2

2

3

High-throughput

0.811

High

1021475

ANK3
Ankyrin-3

2

3

High-throughput

0.811

High

1356311

FEM1B
Protein fem-1 homolog B

2

4

High-throughput

0.811

High

1357893

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

2

14

Small-scale

0.754

High

800850

MK08
Mitogen-activated protein kinase 8

9

9

Small-scale

0.752

High

800963

MK09
Mitogen-activated protein kinase 9

5

9

Small-scale

0.728

High

972470

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

19

Small-scale

0.724

High

1018215

M3K12
Mitogen-activated protein kinase kinase kinase 12

1

20

Small-scale

0.724

High

1268119

MY18A
Unconventional myosin-XVIIIa

1

4

High-throughput

0.691

High

1302000

NEB2
Neurabin-2

1

16

High-throughput

0.691

High

153189

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

3

10

Small-scale

0.678

High

339153

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

678986

HXC8
Homeobox protein Hox-C8

2

9

High-throughput

0.628

High

1057162

TTLL4
Tubulin monoglutamylase TTLL4

2

1

High-throughput

0.628

High

1293597

SENP5
Sentrin-specific protease 5

2

1

High-throughput

0.628

High

1357751

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

2

9

High-throughput

0.628

High

199562

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

15

Small-scale

0.618

High

1022474

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

8

Small-scale

0.618

High

1256289

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

14

Small-scale

0.618

High

957662

LRP2
Low-density lipoprotein receptor-related protein 2

2

20

Small-scale

0.609

High

992729

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

20

Small-scale

0.609

High

1188077

SETX
Probable helicase senataxin

2

0

High-throughput

0.602

High

1048463

LRP8
Low-density lipoprotein receptor-related protein 8

2

20

Small-scale

0.594

High

412413

FYN
Tyrosine-protein kinase Fyn

1

18

High-throughput

0.590

High

992406

KLC1
Kinesin light chain 1

2

6

Small-scale

0.584

High

1316237

DUS16
Dual specificity protein phosphatase 16

1

2

Small-scale

0.578

High

295571

RECQ5
ATP-dependent DNA helicase Q5

1

3

High-throughput

0.541

High

1264745

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.541

High

808323

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

3

High-throughput

0.536

High

1037440

TBB3
Tubulin beta-3 chain

1

10

High-throughput

0.536

High

1049359

KEAP1
Kelch-like ECH-associated protein 1

1

6

High-throughput

0.536

High

1114264

TBB8
Tubulin beta-8 chain

1

10

High-throughput

0.536

High

1205087

VRK2
Serine/threonine-protein kinase VRK2

1

3

Small-scale

0.536

High

161249

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.518

High

497823

TAU
Microtubule-associated protein tau

1

5

Small-scale

0.515

High

1053457

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.513

High

396599

ITB3
Integrin beta-3

1

11

Small-scale

0.501

High

147453

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.479

High

805491

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

8

Small-scale

0.479

High

895568

RAB10
Ras-related protein Rab-10

1

4

Small-scale

0.479

High

973896

PAX2
Paired box protein Pax-2

1

1

Small-scale

0.479

High

402636

JUN
Transcription factor Jun

1

0

Small-scale

0.458

High


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Last updated: 15 Jul 2024