Protein: ZP3
Zona pellucida sperm-binding protein 3 (Sperm receptor) (ZP3A/ZP3B) (Zona pellucida glycoprotein 3) (Zp-3) (Zona pellucida protein C) [Cleaved into: Processed zona pellucida sperm-binding protein 3]

Gene: ZP3
Organism: Homo sapiens
Interactions: 26
UniProt ID: P21754

Gene Ontology (top 5):
GO:0001809 - positive regulation of type IV hypersensitivity
GO:0001825 - blastocyst formation
GO:0002455 - humoral immune response mediated by circulating immunoglobulin
GO:0002687 - positive regulation of leukocyte migration
GO:0002922 - positive regulation of humoral immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

601023

ZP3
Zona pellucida sperm-binding protein 3

2

10

Small-scale

0.804

High

601028

ZP1
Zona pellucida sperm-binding protein 1

2

10

Small-scale

0.712

High

601029

ZP2
Zona pellucida sperm-binding protein 2

2

10

Small-scale

0.712

High

267323

CLD11
Claudin-11

2

0

High-throughput

0.580

High

601031

MALL
MAL-like protein

2

0

High-throughput

0.580

High

601030

ZP4
Zona pellucida sperm-binding protein 4

1

10

Small-scale

0.575

High

601032

UBP2L
Ubiquitin-associated protein 2-like

1

0

Small-scale

0.518

High

601035

SACA3
Sperm acrosome membrane-associated protein 3

1

0

Small-scale

0.518

High

601025

VDAC2
Voltage-dependent anion-selective channel protein 2

1

2

Small-scale

0.515

High

601026

SPB8
Serpin B8

1

0

High-throughput

0.513

High

488433

ACRO
Acrosin

1

6

Small-scale

0.501

High

417152

ENOA
Alpha-enolase

1

2

Small-scale

0.479

High

537800

KPYM
Pyruvate kinase PKM

1

2

Small-scale

0.479

High

601027

TPIS
Triosephosphate isomerase

1

1

Small-scale

0.479

High

601036

OR2LD
Olfactory receptor 2L13

1

0

Small-scale

0.460

High

147698

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

2

Small-scale

0.437

High

597473

GSTM3
Glutathione S-transferase Mu 3

1

1

Small-scale

0.437

High

601024

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

2

Small-scale

0.437

High

601033

ODFP2
Outer dense fiber protein 2

1

2

Small-scale

0.437

High

158313

PCD17
Protocadherin-17

1

0

Small-scale

0.282

High

601037

MILK1
MICAL-like protein 1

1

0

Small-scale

0.282

High

601034

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.279

Low

601038

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

1

0

High-throughput

0.279

Low

601040

RT16
Small ribosomal subunit protein bS16m

1

0

Small-scale

0.251

Low

601039

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024