Protein: DC1L2
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)

Gene: DC1L2, DYNC1LI2
Organism: Homo sapiens
Interactions: 115
UniProt ID: O43237

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000776 - kinetochore
GO:0005524 - ATP binding
GO:0005770 - late endosome
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

198261

DYHC1
Cytoplasmic dynein 1 heavy chain 1

4

2

High-throughput

0.900

High

198311

NINL
Ninein-like protein

3

3

High-throughput

0.827

High

198314

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

2

2

High-throughput

0.811

High

198252

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

6

8

Small-scale

0.734

High

198244

DYLT1
Dynein light chain Tctex-type 1

4

2

High-throughput

0.694

High

198277

RASEF
Ras and EF-hand domain-containing protein

1

2

High-throughput

0.691

High

198243

DYL1
Dynein light chain 1, cytoplasmic

3

3

High-throughput

0.675

High

148018

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

3

9

High-throughput

0.667

High

198312

C2CD2
C2 domain-containing protein 2

3

1

High-throughput

0.667

High

198260

DCTN1
Dynactin subunit 1

3

3

High-throughput

0.656

High

198207

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

2

High-throughput

0.618

High

198238

ACTZ
Alpha-centractin

2

4

High-throughput

0.611

High

198254

DCTN2
Dynactin subunit 2

2

1

High-throughput

0.611

High

198288

DYL2
Dynein light chain 2, cytoplasmic

2

3

High-throughput

0.611

High

198210

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.584

High

198278

NIN
Ninein

2

3

High-throughput

0.584

High

198232

BRCA2
Breast cancer type 2 susceptibility protein

1

1

Small-scale

0.561

High

198221

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

198226

CLIP1
CAP-Gly domain-containing linker protein 1

1

1

High-throughput

0.536

High

198230

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

2

High-throughput

0.536

High

198231

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

198234

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

198245

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.536

High

198247

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

1

High-throughput

0.536

High

198256

CUL3
Cullin-3

1

2

High-throughput

0.536

High

198264

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

High-throughput

0.536

High

198293

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.536

High

198303

DLRB1
Dynein light chain roadblock-type 1

1

1

High-throughput

0.536

High

198251

DEMA
Dematin

1

0

High-throughput

0.518

High

198223

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

198237

PCBP4
Poly(rC)-binding protein 4

1

0

High-throughput

0.513

High

198275

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

174460

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

198286

GLMN
Glomulin

1

1

High-throughput

0.489

High

198215

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

198209

SYNJ1
Synaptojanin-1

1

2

High-throughput

0.479

High

198214

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

198216

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

198219

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

198229

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

198235

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

1

High-throughput

0.479

High

198236

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

198240

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.479

High

198241

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

198242

RB11A
Ras-related protein Rab-11A

1

2

High-throughput

0.479

High

198249

CALD1
Caldesmon

1

2

High-throughput

0.479

High

198253

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

198257

CUL4B
Cullin-4B

1

2

High-throughput

0.479

High

198259

SEPT6
Septin-6

1

2

High-throughput

0.479

High

198262

CASP8
Caspase-8

1

1

High-throughput

0.479

High

198263

ELOB
Elongin-B

1

1

High-throughput

0.479

High

198265

ITSN1
Intersectin-1

1

1

High-throughput

0.479

High

198273

HOOK3
Protein Hook homolog 3

1

3

High-throughput

0.479

High

198283

BICD2
Protein bicaudal D homolog 2

1

3

High-throughput

0.479

High

198284

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

198292

RUFY1
RUN and FYVE domain-containing protein 1

1

1

High-throughput

0.479

High

198294

SH3G1
Endophilin-A2

1

2

High-throughput

0.479

High

198295

COR1B
Coronin-1B

1

5

High-throughput

0.479

High

198296

SRBS1
Sorbin and SH3 domain-containing protein 1

1

2

High-throughput

0.479

High

198298

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.479

High

198304

ARL8B
ADP-ribosylation factor-like protein 8B

1

1

High-throughput

0.479

High

198305

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

198306

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

1

High-throughput

0.479

High

198307

DBNL
Drebrin-like protein

1

3

High-throughput

0.479

High

198218

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.460

High

155210

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

168304

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.458

High

169740

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

0

High-throughput

0.458

High

196239

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

High-throughput

0.458

High

198220

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.458

High

198224

ICAL
Calpastatin

1

0

High-throughput

0.458

High

198248

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

198250

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.458

High

198258

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

198266

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

198268

TUT7
Terminal uridylyltransferase 7

1

0

High-throughput

0.458

High

198274

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.458

High

198280

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.458

High

198282

TRI58
E3 ubiquitin-protein ligase TRIM58

1

0

Small-scale

0.458

High

198290

CCD43
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.458

High

198291

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.458

High

198297

CEP41
Centrosomal protein of 41 kDa

1

0

High-throughput

0.458

High

198302

JUPI2
Jupiter microtubule associated homolog 2

1

0

High-throughput

0.458

High

198308

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

198211

GGYF1
GRB10-interacting GYF protein 1

1

3

High-throughput

0.445

High

198212

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

3

High-throughput

0.437

High

198213

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

198217

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

198222

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

198228

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

198239

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.437

High

198269

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

198271

MAVS
Mitochondrial antiviral-signaling protein

1

3

High-throughput

0.437

High

198276

PHAR4
Phosphatase and actin regulator 4

1

2

High-throughput

0.437

High

198281

ARL10
ADP-ribosylation factor-like protein 10

1

2

High-throughput

0.437

High

198285

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

198301

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

198309

COR1C
Coronin-1C

1

3

High-throughput

0.437

High

198233

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.279

Low

198255

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

198300

CSTL1
Cystatin-like 1

1

0

High-throughput

0.279

Low

198208

TPD54
Tumor protein D54

1

0

High-throughput

0.249

Low

198225

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

198227

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

198267

ATG2A
Autophagy-related protein 2 homolog A

1

0

High-throughput

0.249

Low

198272

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

198279

RP25L
Ribonuclease P protein subunit p25-like protein

1

0

High-throughput

0.249

Low

198287

EFHD2
EF-hand domain-containing protein D2

1

0

High-throughput

0.249

Low

198289

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.249

Low

198299

TANC1
Protein TANC1

1

0

High-throughput

0.249

Low

198310

PLAK2
PALM2-AKAP2 fusion protein

1

0

High-throughput

0.249

Low

198313

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.249

Low

198270

Q6ZUH1
cDNA FLJ43719 fis, clone TESOP2006060

1

0

High-throughput

0.238

Low

198246

TAGL
Transgelin

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024