Protein: FLP1
Tyrosine-protein phosphatase CDC14 homolog (EC 3.1.3.48) (CDC fourteen-like phosphatase 1)

Gene: FLP1, clp1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 140
UniProt ID: Q9P7H1

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000776 - kinetochore
GO:0000917 - division septum assembly
GO:0000922 - spindle pole
GO:0004721 - phosphoprotein phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

410463

CDK1
Cyclin-dependent kinase 1

2

5

Small-scale

0.778

High

896102

STE20
Serine/threonine-protein kinase shk1/pak1

1

4

High-throughput

0.724

High

840579

RAD24
Checkpoint signal transducer rad24

4

9

Small-scale

0.692

High

444671

MPIP
M-phase inducer phosphatase

4

3

Small-scale

0.683

High

785745

DSK1
Protein kinase dsk1

1

6

High-throughput

0.647

High

1363015

SPM1
Mitogen-activated protein kinase spm1

1

19

Small-scale

0.647

High

1455048

FLP1
Tyrosine-protein phosphatase CDC14 homolog

1

18

Small-scale

0.647

High

1273321

NSK1
Kinetochore protein nsk1

2

2

Small-scale

0.624

High

237726

AURK
Aurora kinase

1

8

Small-scale

0.618

High

268303

RRP5
rRNA biogenesis protein rrp5

1

1

High-throughput

0.618

High

314928

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase bub1

1

9

High-throughput

0.618

High

654010

KIN1
Protein kinase kin1

1

7

High-throughput

0.618

High

834927

RES2
Cell division cycle-related protein res2/pct1

1

17

High-throughput

0.618

High

1066835

RAD53
Serine/threonine-protein kinase cds1

1

8

Small-scale

0.618

High

207233

MDE4
Monopolin complex subunit mde4

2

0

Small-scale

0.598

High

1169065

KLP9
Kinesin-like motor protein 9

2

13

Small-scale

0.595

High

1009054

BUD4
Anillin-related medial ring protein mid1

2

0

Small-scale

0.593

High

1068590

CDC15
Cell division control protein 15

2

2

Small-scale

0.584

High

150899

PCS1
Monopolin complex subunit pcs1

2

0

Small-scale

0.576

High

207216

SEP1
Forkhead protein sep1

1

4

High-throughput

0.561

High

237659

KLP6
Kinesin-like protein 6

1

11

High-throughput

0.561

High

267743

CDC11
Septation initiation network scaffold protein cdc11

1

6

High-throughput

0.561

High

376451

CDC10
Start control protein cdc10

1

20

High-throughput

0.561

High

753777

RES1
Cell division cycle-related protein res1/sct1

1

19

High-throughput

0.561

High

1455058

PUB2
E3 ubiquitin-protein ligase pub2

1

11

Small-scale

0.561

High

1455059

DYLT
Dynein light chain Tctex-type

2

0

Small-scale

0.559

High

206931

NRM1
Transcription factor nrm1

1

0

High-throughput

0.537

High

828290

SAP1
Switch-activating protein 1

1

0

High-throughput

0.537

High

267511

DNT1
Nucleolar protein dnt1

1

4

Small-scale

0.508

High

1439769

ASE1
Anaphase spindle elongation protein 1

1

9

Small-scale

0.501

High

151158

NOP12
Nucleolar protein 12

1

1

High-throughput

0.479

High

151229

CSX1
RNA-binding post-transcriptional regulator csx1

1

2

High-throughput

0.479

High

151683

DRI1
RNA-binding protein involved in heterochromatin assembly dri1

1

10

High-throughput

0.479

High

152469

OLA1
Obg-like ATPase 1

1

2

High-throughput

0.479

High

152697

BIR1
Chromosomal passenger complex protein bir1

1

4

High-throughput

0.479

High

152928

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

153314

MYO3
Myosin type-2 heavy chain 2

1

8

High-throughput

0.479

High

153431

IQG1
Ras GTPase-activating-like protein rng2

1

9

High-throughput

0.479

High

153540

SFC1
Transcription factor tau subunit sfc1

1

1

High-throughput

0.479

High

153569

NOG2
Nucleolar GTP-binding protein 2

1

4

High-throughput

0.479

High

153769

YF19
Putative aldehyde dehydrogenase-like protein C9E9.09c

1

3

High-throughput

0.479

High

153817

YE8A
Probable inositol polyphosphate 5-phosphatase C9G1.10c

1

1

High-throughput

0.479

High

153942

KLP5
Kinesin-like protein 5

1

10

High-throughput

0.479

High

153948

IMDH
Inosine-5'-monophosphate dehydrogenase

1

2

High-throughput

0.479

High

205981

YF82
GRIP and coiled-coil domain-containing protein C27D7.02c

1

10

High-throughput

0.479

High

206152

BUB3
Spindle assembly checkpoint protein bub3

1

8

High-throughput

0.479

High

207155

SRE2
Putative transcription factor sre2

1

2

High-throughput

0.479

High

267377

FKBP4
FK506-binding protein 39 kDa

1

5

High-throughput

0.479

High

267486

DCA13
Protein sof1

1

10

High-throughput

0.479

High

267582

YOCE
Uncharacterized RNA-binding protein C4F6.14

1

3

High-throughput

0.479

High

267640

UBP16
Probable ubiquitin carboxyl-terminal hydrolase 16

1

3

High-throughput

0.479

High

267667

SCW1
Cell wall integrity protein scw1

1

5

High-throughput

0.479

High

267673

STS5
Protein sts5

1

2

High-throughput

0.479

High

267690

SFC4
Transcription factor tau subunit sfc4

1

2

High-throughput

0.479

High

267708

YQC1
Uncharacterized protein C1739.01

1

2

High-throughput

0.479

High

267751

IMB3
Importin subunit beta-3

1

15

High-throughput

0.479

High

267924

POB1
Protein pob1

1

3

High-throughput

0.479

High

268798

YQL5
Uncharacterized RNA-binding protein C1827.05c

1

3

High-throughput

0.479

High

314213

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

314346

ALP14
Spindle pole body component alp14

1

15

High-throughput

0.479

High

314768

NSA1
Ribosome biogenesis protein nsa1

1

2

High-throughput

0.479

High

567154

PP11
Serine/threonine-protein phosphatase PP1-1

1

3

High-throughput

0.479

High

618821

IPYR
Inorganic pyrophosphatase

1

1

High-throughput

0.479

High

785564

ARF1
ADP-ribosylation factor 1

1

6

High-throughput

0.479

High

785775

PMGY
Phosphoglycerate mutase

1

3

High-throughput

0.479

High

789362

DIS3
Exosome complex exonuclease dis3

1

2

High-throughput

0.479

High

823574

XRN1
5'-3' exoribonuclease 1

1

2

High-throughput

0.479

High

836393

PRS8
26S proteasome regulatory subunit 8 homolog

1

9

High-throughput

0.479

High

840593

RAD25
Checkpoint signal transducer rad25

1

8

High-throughput

0.479

High

1017846

RPN1
26S proteasome regulatory subunit rpn1

1

5

High-throughput

0.479

High

1034664

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.479

High

1042334

PRH1
Probable ATP-dependent RNA helicase prh1

1

3

High-throughput

0.479

High

1066868

MLR4
Myosin regulatory light chain cdc4

1

2

High-throughput

0.479

High

1068452

RRP4
Exosome complex component rrp4

1

1

High-throughput

0.479

High

1068494

YA4C
Arrestin domain-containing protein C31A2.12

1

2

High-throughput

0.479

High

1068584

RENT1
ATP-dependent helicase upf1

1

5

High-throughput

0.479

High

1068731

HAS1
ATP-dependent RNA helicase has1

1

6

High-throughput

0.479

High

1082797

SYG
Putative glycine--tRNA ligase

1

1

High-throughput

0.479

High

1082886

GAF1
Transcription factor gaf1

1

1

High-throughput

0.479

High

1197952

SPC19
DASH complex subunit spc19

1

1

High-throughput

0.479

High

1403845

COPA
Putative coatomer subunit alpha

1

4

High-throughput

0.479

High

1421387

VPS5
Vacuolar protein sorting-associated protein vps5

1

5

High-throughput

0.479

High

1454979

RM09
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.479

High

1455005

YN8E
Pumilio domain-containing protein P35G2.14

1

1

High-throughput

0.479

High

1455037

APP1
Protein app1

1

9

High-throughput

0.479

High

1455050

DNA2
DNA replication ATP-dependent helicase/nuclease dna2 [Includes: DNA replication nuclease dna2

1

5

High-throughput

0.479

High

1455052

CLC1
Clathrin light chain

1

2

High-throughput

0.479

High

1455055

MRT4
Ribosome assembly factor mrt4

1

2

High-throughput

0.479

High

1455056

2AAA
Protein phosphatase PP2A regulatory subunit A

1

11

Small-scale

0.479

High

1455057

RL1DB
Putative ribosome biogenesis protein C8F11.04

1

3

High-throughput

0.479

High

1455061

AP1G1
AP-1 complex subunit gamma-1

1

5

High-throughput

0.479

High

1455063

RGF3
Rho1 guanine nucleotide exchange factor 3

1

5

High-throughput

0.479

High

1455064

MYO1
Myosin-1

1

17

High-throughput

0.479

High

150686

SFC9
Putative transcription factor tau subunit sfc9

1

0

High-throughput

0.458

High

151048

MUG61
Meiotically up-regulated gene 61 protein

1

0

High-throughput

0.458

High

152660

PNO1
Pre-rRNA-processing protein pno1

1

0

High-throughput

0.458

High

153811

CYK3
cytokinesis protein 3

1

0

High-throughput

0.458

High

207171

RGA6
Probable Rho-GTPase-activating protein 6

1

0

High-throughput

0.458

High

238053

BAG1A
BAG family molecular chaperone regulator 1A

1

0

High-throughput

0.458

High

267481

BLT1
Mitosis inducer protein blt1

1

0

High-throughput

0.458

High

267597

YJL4
Uncharacterized protein C14G10.04

1

0

High-throughput

0.458

High

267622

COIL
Coilin

1

0

High-throughput

0.458

High

267747

FKS4
1,3-beta-glucan synthase component bgs4

1

0

High-throughput

0.458

High

268095

MMB1
Microtubule-associated protein mmb1

1

0

High-throughput

0.458

High

313897

MU118
Meiotically up-regulated gene 118 protein

1

0

High-throughput

0.458

High

314694

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

828625

YOX1
MBF complex negative regulatory component yox1

1

0

High-throughput

0.458

High

1008977

UGPA1
Probable UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.458

High

1017964

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.458

High

1066572

RNP24
RNA-binding protein rnp24

1

0

High-throughput

0.458

High

1068393

LYS1
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

1

0

High-throughput

0.458

High

1068577

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.458

High

1082909

YD4B
Uncharacterized protein C22H10.11c

1

0

High-throughput

0.458

High

1169057

INCE
Inner centromere protein pic1

1

0

High-throughput

0.458

High

1403850

YNH5
UPF0642 protein C32H8.05

1

0

High-throughput

0.458

High

1455051

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.458

High

1455053

SFC3
Transcription factor tau subunit sfc3

1

0

High-throughput

0.458

High

1455054

ATH1
Ataxin-2 homolog

1

0

High-throughput

0.458

High

1455060

NSA2
Ribosome biogenesis protein nsa2

1

0

High-throughput

0.458

High

1455062

PAL1
Protein pal1

1

0

High-throughput

0.458

High

150468

SAHH
Adenosylhomocysteinase

1

8

High-throughput

0.437

High

152708

ATC4
Endoplasmic reticulum transmembrane helix translocase

1

8

High-throughput

0.437

High

207011

YBP8
Uncharacterized ABC transporter ATP-binding protein C16H5.08c

1

3

High-throughput

0.437

High

207127

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.437

High

238280

UTP10
U3 small nucleolar RNA-associated protein 10

1

3

High-throughput

0.437

High

267603

ENT1
Epsin-1

1

1

High-throughput

0.437

High

267629

YJE9
Uncharacterized mitochondrial carrier C1682.09c

1

5

High-throughput

0.437

High

314284

YN67
Putative enoyl reductase C646.07c

1

3

High-throughput

0.437

High

643595

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.437

High

1082639

GCN1
eIF-2-alpha kinase activator gcn1

1

20

High-throughput

0.437

High

1455049

MPCP
Probable mitochondrial phosphate carrier protein

1

5

High-throughput

0.437

High

207042

MBX1
MADS-box transcription factor 1

2

0

Small-scale

0.333

High

151885

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

Small-scale

0.251

Low

151857

SEL1
Eisosome protein sle1

1

0

High-throughput

0.249

Low

267824

PROD
Probable proline dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

436574

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.249

Low

823543

MAOX
NAD-dependent malic enzyme

1

0

High-throughput

0.249

Low

1018129

CUE4
CUE domain-containing protein 4, mitochondrial

1

0

High-throughput

0.249

Low

1362960

PFL8
Putative cell agglutination protein pfl8

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025